Výsledky vyhledávání - Transcription Factor Networks in Reprogramming

Abstract 2938 Dissecting the Epigenetic and Transcriptional Dynamics of Somatic-to-iPS Reprogramming at Single-Cell Resolution Autor Petenkaya, Aydolun, Menhart, Mary, Leung, Eva, Joves, Ken, Plath, Kathrin, Dror, Iris, Chronis, Constantinos

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The pluripotency transcription factor network at work in reprogramming Autor Niwa, Hitoshi

“…-associated transcription factor network…”
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Single-cell sequencing revealed metabolic reprogramming and its transcription factor regulatory network in prostate cancer Autor Wei, Guojiang, Zhu, Hongcai, Zhou, Yupeng, Pan, Yang, Yi, Bocun, Bai, Yangkai

“…: Insights from Single-Cell Sequencing.•Unlocking Metabolic Variations and Transcription Factor Dynamics Across Distinct Prostate Cancer Subtypes via Single-Cell Sequencing…”
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Lessons from a transcription factor: Alx1 provides insights into gene regulatory networks, cellular reprogramming, and cell type evolution Autor Ettensohn, Charles A, Guerrero-Santoro, Jennifer, Khor, Jian Ming

“… The homeodomain-containing transcription factor, Alx1, was originally shown to be a core component of the skeletogenic GRN of the sea urchin embryo…”
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Diverse reprogramming codes for neuronal identity Autor Tsunemoto, Rachel, Lee, Sohyon, Szűcs, Attila, Chubukov, Pavel, Sokolova, Irina, Blanchard, Joel W., Eade, Kevin T., Bruggemann, Jacob, Wu, Chunlei, Torkamani, Ali, Sanna, Pietro Paolo, Baldwin, Kristin K.

“… The relationship between reprogramming factors and the transcriptional networks that produce neuronal identity and diversity remains largely unknown…”
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Krüppel-like factor 1 is a core cardiomyogenic trigger in zebrafish Autor Ogawa, Masahito, Geng, Fan-Suo, Humphreys, David T, Kristianto, Esther, Sheng, Delicia Z, Hui, Subhra P, Zhang, Yuxi, Sugimoto, Kotaro, Nakayama, Maki, Zheng, Dawei, Hesselson, Daniel, Hodson, Mark P, Bogdanovic, Ozren, Kikuchi, Kazu

“… Transient Klf1 activation is sufficient to expand mature myocardium in uninjured hearts. Klf1 directs epigenetic reprogramming of the cardiac transcription factor network, permitting coordinated cardiomyocyte dedifferentiation and proliferation…”
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Liver-fibrosis-activated transcriptional networks govern hepatocyte reprogramming and intra-hepatic communication Autor Loft, Anne, Alfaro, Ana Jimena, Schmidt, Søren Fisker, Pedersen, Felix Boel, Terkelsen, Mike Krogh, Puglia, Michele, Chow, Kan Kau, Feuchtinger, Annette, Troullinaki, Maria, Maida, Adriano, Wolff, Gretchen, Sakurai, Minako, Berutti, Riccardo, Ekim Üstünel, Bilgen, Nawroth, Peter, Ravnskjaer, Kim, Diaz, Mauricio Berriel, Blagoev, Blagoy, Herzig, Stephan

“… The hepatocyte reprogramming was under tight cooperative control of a network of fibrosis-activated transcription factors, as exemplified by the transcription factor Elf-3 (ELF3…”
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Cellular reprogramming by transcription factor engineering Autor Tsang, Jason CH, Gao, Xuefei, Lu, Liming, Liu, Pentao

“… Recent researches have identified multiple transcription factors as permissible reprogramming factors to pluripotency and lineage switching…”
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In Vivo Cellular Reprogramming: The Next Generation Autor Srivastava, Deepak, DeWitt, Natalie

“… While a combinatorial code was initially found to reprogram somatic cells to pluripotency, a "second generation" of cellular reprogramming involves lineage-restricted transcription factors and micro…”
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A Gene Regulatory Network for Cellular Reprogramming in Plant Regeneration Autor Ikeuchi, Momoko, Shibata, Michitaro, Rymen, Bart, Iwase, Akira, B�gman, Anne-Maarit, Watt, Lewis, Coleman, Duncan, Favero, David S, Takahashi, Tatsuya, Ahnert, Sebastian E, Brady, Siobhan M, Sugimoto, Keiko

“…) associated with plant cellular reprogramming by using an enhanced yeast one-hybrid (eY1H) screen systematically to identify regulatory relationships between 252 transcription factors (TFs) and 48 promoters…”
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Klf4 glutamylation is required for cell reprogramming and early embryonic development in mice Autor Ye, Buqing, Liu, Benyu, Hao, Lu, Zhu, Xiaoxiao, Yang, Liuliu, Wang, Shuo, Xia, Pengyan, Du, Ying, Meng, Shu, Huang, Guanling, Qin, Xiwen, Wang, Yanying, Yan, Xinlong, Li, Chong, Hao, Junfeng, Zhu, Pingping, He, Luyun, Tian, Yong, Fan, Zusen

“…Temporal and spatial-specific regulation of pluripotency networks is largely dependent on the precise modifications of core transcription factors…”
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Network analysis of transcription factors for nuclear reprogramming into induced pluripotent stem cell using bioinformatics Autor Chakraborty, Chiranjib, S Roy, Sanjiban, J Hsu, Minna, Agoramoorthy, Govindasamy

“… As there is a lack of data on intra- and inter-networking among these six different transcription factors, the objective of this study is to analyze the intra- and inter-networks between them using bioinformatic…”
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Transcriptional pause release is a rate-limiting step for somatic cell reprogramming Autor Liu, Longqi, Xu, Yan, He, Minghui, Zhang, Meng, Cui, Fenggong, Lu, Leina, Yao, Mingze, Tian, Weihua, Benda, Christina, Zhuang, Qiang, Huang, Zhijian, Li, Wenjuan, Li, Xiangchun, Zhao, Ping, Fan, Wenxia, Luo, Zhiwei, Li, Yuan, Wu, Yasong, Hutchins, Andrew P, Wang, Dongye, Tse, Hung-Fat, Schambach, Axel, Frampton, Jon, Qin, Baoming, Bao, Xichen, Yao, Hongjie, Zhang, Biliang, Sun, Hao, Pei, Duanqing, Wang, Huating, Wang, Jun, Esteban, Miguel A

“…Reactivation of the pluripotency network during somatic cell reprogramming by exogenous transcription factors involves chromatin remodeling and the recruitment of RNA polymerase II (Pol II) to target loci…”
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NKX3-1 is required for induced pluripotent stem cell reprogramming and can replace OCT4 in mouse and human iPSC induction Autor Mai, Thach, Markov, Glenn J., Brady, Jennifer J., Palla, Adelaida, Zeng, Hong, Sebastiano, Vittorio, Blau, Helen M.

“… Reprogramming somatic cells to induced pluripotent stem cells (iPSCs) is now routinely accomplished by overexpression of the four Yamanaka factors…”
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Reprogramming and remodeling: transcriptional and epigenetic regulation of salicylic acid-mediated plant defense Autor Chen, Jian, Clinton, Michael, Qi, Guang, Wang, Daowen, Liu, Fengquan, Fu, Zheng Qing

“… Plant transcription factors and their co-regulators are critical players in establishing a transcription regulatory network and boosting plant immunity…”
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A single factor elicits multilineage reprogramming of astrocytes in the adult mouse striatum Autor Zhang, Yunjia, Li, Boxun, Cananzi, Sergio, Han, Chuanhui, Wang, Lei-Lei, Zou, Yuhua, Fu, Yang-Xin, Hon, Gary C, Zhang, Chun-Li

“… In this study, we performed a series of in vivo screens and reveal that a single factor can induce resident brain astrocytes to become induced neural progenitor cells (iNPCs…”
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Delineating chromatin accessibility re-patterning at single cell level during early stage of direct cardiac reprogramming Autor Wang, Haofei, Yang, Yuchen, Qian, Yunzhe, Liu, Jiandong, Qian, Li

“…) on early reprogramming iCMs given the known epigenetic changes as early as day 3. This approach unveiled networks of transcription factors (TFs…”
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Transcriptional reprogramming at the intersection of the heat shock response and proteostasis Autor Pessa, Jenny C, Joutsen, Jenny, Sistonen, Lea

“… The dramatic rewiring of gene and enhancer networks is driven by key transcription factors, including heat shock factors (HSFs…”
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DeepNEU: cellular reprogramming comes of age – a machine learning platform with application to rare diseases research Autor Danter, Wayne R.

“… We have developed an unsupervised deep machine learning technology, called DeepNEU that is based on a fully-connected recurrent neural network…”
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Nac1 facilitates pluripotency gene activation for establishing somatic cell reprogramming Autor Choi, Hwan, Park, Hyeok Ju, Kim, Hongwon, Kim, Junyeop, Lee, Yong Kyu, Kim, Jongpil

“…Transcription factors play a central role in pluripotency transcription circuitry for establishing pluripotent reprogramming…”
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