Suchergebnisse - Protein Array Analysis/methods

Retinal pigment epithelium (RPE) exosomes contain signaling phosphoproteins affected by oxidative stress von Biasutto, Lucia, Chiechi, Antonella, Couch, Robin, Liotta, Lance A., Espina, Virginia

“… presence of phosphorylated signaling proteins in the vitreous humour of patients affected by AMD or other retinal diseases …”
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Self-Assembled Peptide Nanoarrays: An Approach to Studying Protein-Protein Interactions von Williams, Berea A. R., Lund, Kyle, Liu, Yan, Yan, Hao, Chaput, John C.

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Randomly oriented ZnO nanorods as advanced substrate for high-performance protein microarrays von Hu, Weihua, Liu, Yingshuai, Zhu, Zhihong, Yang, Hongbin, Li, Chang Ming

“… A nanostructure with randomly oriented ZnO nanorods was prepared on the glass slides using scalable method as a protein microarray substrate …”
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Erkitinib, a novel EGFR tyrosine kinase inhibitor screened using a ProteoChip system from a phytochemical library von Kim, Eung-Yoon, Choi, Young-Jin, Park, Chan-Won, Kang, In-Cheol

“… Receptor tyrosine kinases (PTKs) play key roles in the pathogenesis of numerous human diseases, including cancer. Therefore PTK inhibitors are currently under …”
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Nanosystems for biosensing: multianalyte immunoassay on a protein chip von Tamiya, Eiichi, Zhi, Zheng-Liang, Morita, Yasutaka, Hasan, Quamrul

“… This chapter describes the construction of addressable two-dimensional (2D) microarrays via the random fluidic self-assembly of metallic particles and the use of these arrays as platforms for constructing protein chips for bioassays …”
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Cytokine mRNA profiling identifies B cells as a major source of RANKL in rheumatoid arthritis von Yeo, Lorraine, Toellner, Kai-Michael, Salmon, Mike, Filer, Andrew, Buckley, Christopher D, Raza, Karim, Scheel-Toellner, Dagmar

“… Objectives In rheumatoid arthritis (RA), a complex cytokine network drives chronic inflammation and joint destruction. So far, few attempts have been made to …”
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Identifying blood biomarkers for mood disorders using convergent functional genomics von Le-Niculescu, H, Kurian, S M, Yehyawi, N, Dike, C, Patel, S D, Edenberg, H J, Tsuang, M T, Salomon, D R, Nurnberger, J I, Niculescu, A B

“… There are to date no objective clinical laboratory blood tests for mood disorders. The current reliance on patient self-report of symptom severity and on the …”
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Multicolor quantum dots for molecular diagnostics of cancer von Smith, Andrew M, Dave, Shivang, Nie, Shuming, True, Lawrence, Gao, Xiaohu

“… as contrast agents for medical imaging. With the emergence of gene and protein profiling and microarray technology, high-throughput screening of biomarkers has generated databases of genomic and expression data for certain cancer types …”
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OMICS-driven biomarker discovery in nutrition and health von Kussmann, Martin, Raymond, Frédéric, Affolter, Michael

“… Nutrigenomics addresses the inverse relationship, that is how diet influences gene transcription, protein expression and metabolism …”
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Enzyme assays for high-throughput screening von Goddard, Jean-Philippe, Reymond, Jean-Louis

“… Assaying enzyme-catalyzed transformations in high-throughput is crucial to enzyme discovery, enzyme engineering and the drug discovery process. In enzyme …”
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Mast cell heterogeneity underlies different manifestations of food allergy in mice von Benedé, Sara, Berin, M. Cecilia

“… Food can trigger a diverse array of symptoms in food allergic individuals from isolated local symptoms affecting skin or gut to multi-system severe reactions …”
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Response to Long-Term NaHCO3-Derived Alkalinity in Model Lotus japonicus Ecotypes Gifu B-129 and Miyakojima MG-20: Transcriptomic Profiling and Physiological Characterization von Babuin, María Florencia, Campestre, María Paula, Rocco, Rubén, Bordenave, Cesar D., Escaray, Francisco J., Antonelli, Cristian, Calzadilla, Pablo, Gárriz, Andrés, Serna, Eva, Carrasco, Pedro, Ruiz, Oscar A., Menendez, Ana B.

“… The current knowledge regarding transcriptomic changes induced by alkalinity on plants is scarce and limited to studies where plants were subjected to the …”
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Homogeneous reporter system enables quantitative functional assessment of multiple transcription factors von Romanov, Sergei, Medvedev, Alexander, Gambarian, Maria, Poltoratskaya, Natalia, Moeser, Matt, Medvedeva, Liubov, Gambarian, Mikhail, Diatchenko, Luda, Makarov, Sergei

“… We developed a high-content reporter system that allows quantitative assessment of activities of multiple transcription factors (TFs) in a eukaryotic cell. The …”
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Populus homeobox gene ARBORKNOX1 reveals overlapping mechanisms regulating the shoot apical meristem and the vascular cambium von Groover, A.T, Mansfield, S.D, DiFazio, S.P, Dupper, G, Fontana, J.R, Millar, R, Wang, Y

“… % of genes up-regulated in the stems of ARK1 over-expressing plants encode proteins involved in extracellular matrix synthesis or modification, including proteins involved …”
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Linker Flexibility Facilitates Module Exchange in Fungal Hybrid PKS-NRPS Engineering von Nielsen, Maria Lund, Isbrandt, Thomas, Petersen, Lene Maj, Mortensen, Uffe Hasbro, Andersen, Mikael Rørdam, Hoof, Jakob Blæsbjerg, Larsen, Thomas Ostenfeld

“… Polyketide synthases (PKSs) and nonribosomal peptide synthetases (NRPSs) each give rise to a vast array of complex bioactive molecules with further complexity added by the existence of natural PKS-NRPS fusions …”
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GeneTrailExpress: a web-based pipeline for the statistical evaluation of microarray experiments von Keller, Andreas, Backes, Christina, Al-Awadhi, Maher, Gerasch, Andreas, Küntzer, Jan, Kohlbacher, Oliver, Kaufmann, Michael, Lenhof, Hans-Peter

“… While the noisiness of the data necessitates an extensive pre-processing of the raw data, the high dimensionality requires effective statistical analysis methods that facilitate the identification of …”
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Lipid Bilayers Are Long-Lived on Solvent Cleaned Plasma-Oxidized poly(dimethyl)siloxane (ox-PDMS) von Faysal, K. M. Rifat, Park, June S., Nguyen, Jonny, Garcia, Luis, Subramaniam, Anand Bala

“… Although it is well known that phospholipids self-assemble on hydrophilic plasma-oxidized PMDS surfaces (ox-PDMS) to form cell membrane mimetic bilayers, the …”
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ENCODE Tiling Array Analysis Identifies Differentially Expressed Annotated and Novel 5′ Capped RNAs in Hepatitis C Infected Liver von Folkers, Milan E., Delker, Don A., Maxwell, Christopher I., Nelson, Cassie A., Schwartz, Jason J., Nix, David A., Hagedorn, Curt H.

“… We hypothesized that using ENCODE tiling arrays (1% of the genome) in combination with affinity purifying Pol II RNAs by their unique 5 …”
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Exposure to Indoor Allergens in Different Residential Settings and Its Influence on IgE Sensitization in a Geographically Confined Austrian Cohort von Stemeseder, Teresa, Schweidler, Bettina, Doppler, Patrick, Klinglmayr, Eva, Moser, Stephanie, Lueftenegger, Lisa, Himly, Martin, Lang, Roland, Zumbach, Joerg, Oostingh, Gertie J., Hawranek, Thomas, Bathke, Arne C., Gadermaier, Gabriele

“… Serum samples of participants were analyzed for specific IgE to Der p 1, Der p 2, Fel d 1, Can f 1 and Alt a 1 using the multiplex array ImmunoCAP ISAC …”
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From gene expression to serum proteins: biomarker discovery in ankylosing spondylitis von Haroon, N, Tsui, F W L, O’Shea, F D, Chiu, B, Tsui, H W, Zhang, H, Marshall, K W, Inman, R D

“… ), C-reactive protein (CRP) and the Bath AS disease activity index.Results:Post-infliximab, 69% of the patients (11/16) achieved an ASAS20 response …”
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