Suchergebnisse - Nature Portfolio

A SARS-CoV-2 protein interaction map reveals targets for drug repurposing von Gordon, David E, Jang, Gwendolyn M, Bouhaddou, Mehdi, Xu, Jiewei, Obernier, Kirsten, White, Kris M, O'Meara, Matthew J, Rezelj, Veronica V, Guo, Jeffrey Z, Swaney, Danielle L, Tummino, Tia A, Hüttenhain, Ruth, Kaake, Robyn M, Richards, Alicia L, Tutuncuoglu, Beril, Foussard, Helene, Batra, Jyoti, Haas, Kelsey, Modak, Maya, Kim, Minkyu, Haas, Paige, Polacco, Benjamin J, Braberg, Hannes, Fabius, Jacqueline M, Eckhardt, Manon, Soucheray, Margaret, Bennett, Melanie J, Cakir, Merve, McGregor, Michael J, Li, Qiongyu, Meyer, Bjoern, Roesch, Ferdinand, Vallet, Thomas, Mac Kain, Alice, Miorin, Lisa, Moreno, Elena, Naing, Zun Zar Chi, Zhou, Yuan, Peng, Shiming, Shi, Ying, Zhang, Ziyang, Shen, Wenqi, Kirby, Ilsa T, Melnyk, James E, Chorba, John S, Lou, Kevin, Dai, Shizhong A, Barrio-Hernandez, Inigo, Memon, Danish, Hernandez-Armenta, Claudia, Lyu, Jiankun, Mathy, Christopher J P, Perica, Tina, Pilla, Kala Bharath, Ganesan, Sai J, Saltzberg, Daniel J, Rakesh, Ramachandran, Liu, Xi, Rosenthal, Sara B, Calviello, Lorenzo, Venkataramanan, Srivats, Liboy-Lugo, Jose, Lin, Yizhu, Huang, Xi-Ping, Liu, YongFeng, Wankowicz, Stephanie A, Bohn, Markus, Safari, Maliheh, Ugur, Fatima S, Koh, Cassandra, Savar, Nastaran Sadat, Tran, Quang Dinh, Shengjuler, Djoshkun, Fletcher, Sabrina J, O'Neal, Michael C, Cai, Yiming, Chang, Jason C J, Broadhurst, David J, Klippsten, Saker, Sharp, Phillip P, Wenzell, Nicole A, Kuzuoglu-Ozturk, Duygu, Wang, Hao-Yuan, Trenker, Raphael, Young, Janet M, Cavero, Devin A, Hiatt, Joseph, Roth, Theodore L, Rathore, Ujjwal, Subramanian, Advait, Noack, Julia, Hubert, Mathieu, Stroud, Robert M, Frankel, Alan D, Rosenberg, Oren S, Verba, Kliment A, Agard, David A, Ott, Melanie, Emerman, Michael, Jura, Natalia

“… A newly described coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is the causative agent of coronavirus disease 2019 …”
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Interfacial engineering of Bi2S3/Ti3C2T x MXene based on work function for rapid photo-excited bacteria-killing von Jianfang Li, Zhaoyang Li, Xiangmei Liu, Changyi Li, Yufeng Zheng, Kelvin Wai Kwok Yeung, Zhenduo Cui, Yanqin Liang, Shengli Zhu, Wenbin Hu, Yajun Qi, Tianjin Zhang, Xianbao Wang, Shuilin Wu

“… MXenes have emerged as potential antimicrobial materials. Here, the authors report on the creation of a Schottky junction to increase the charge separation …”
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Human gut bacteria produce TH17-modulating bile acid metabolites von Paik, Donggi, Yao, Lina, Zhang, Yancong, Bae, Sena, D’Agostino, Gabriel D., Zhang, Minghao, Kim, Eunha, Franzosa, Eric A., Avila-Pacheco, Julian, Bisanz, Jordan E., Rakowski, Christopher K., Vlamakis, Hera, Xavier, Ramnik J., Turnbaugh, Peter J., Longman, Randy S., Krout, Michael R., Clish, Clary B., Rastinejad, Fraydoon, Huttenhower, Curtis, Huh, Jun R., Devlin, A. Sloan

“… The microbiota modulates gut immune homeostasis. Bacteria influence the development and function of host immune cells, including T helper cells expressing …”
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Emergence and clonal expansion of in vitro artemisinin-resistantPlasmodium falciparum kelch13R561H mutant parasites in Rwanda von Uwimana, A., Legrand, E., Stokes, B. H., Ndikumana, J. L. M., Warsame, Marian, Umulisa, N., Ngamije, D., Munyaneza, T., Mazarati, J. B., Munguti, K., Campagne, P., Criscuolo, A., Ariey, F., Murindahabi, M., Ringwald, P., Fidock, D. A., Mbituyumuremyi, A., Menard, D.

“… Artemisinin resistance (delayedP. falciparumclearance following artemisinin-based combination therapy), is widespread across Southeast Asia but to date has not …”
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Emerging MDR-Pseudomonas aeruginosa in fish commonly harbor oprL and toxA virulence genes and bla TEM , bla CTX-M , and tetA antibiotic-resistance genes von Algammal, Abdelazeem M, Mabrok, Mahmoud, Sivaramasamy, Elayaraja, Youssef, Fatma M, Atwa, Mona H, El-Kholy, Ali W, Hetta, Helal F, Hozzein, Wael N

“… This study aimed to investigate the prevalence, antibiogram of Pseudomonas aeruginosa (P. aeruginosa), and the distribution of virulence genes (oprL, exoS, …”
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Angstrom-confined catalytic water purification within Co-TiO x laminar membrane nanochannels von Meng, Chenchen, Ding, Baofu, Zhang, Shaoze, Cui, Lele, Ostrikov, Kostya Ken, Huang, Ziyang, Yang, Bo, Kim, Jae-Hong, Zhang, Zhenghua

“… The freshwater scarcity and inadequate access to clean water globally have rallied tremendous efforts in developing robust technologies for water purification …”
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APOE4 homozygozity represents a distinct genetic form of Alzheimer's disease von Fortea, Juan, Pegueroles, Jordi, Alcolea, Daniel, Belbin, Olivia, Dols-Icardo, Oriol, Vaqué-Alcázar, Lídia, Videla, Laura, Gispert, Juan Domingo, Suárez-Calvet, Marc, Johnson, Sterling C, Sperling, Reisa, Bejanin, Alexandre, Lleó, Alberto, Montal, Víctor

“… This study aimed to evaluate the impact of APOE4 homozygosity on Alzheimer's disease (AD) by examining its clinical, pathological and biomarker changes to see …”
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eGeminal-atom catalysis for cross-coupling von Hai, Xiao, Zheng, Yang, Yu, Qi, Guo, Na, Xi, Shibo, Zhao, Xiaoxu, Mitchell, Sharon, Luo, Xiaohua, Tulus, Victor, Wang, Mu, Sheng, Xiaoyu, Ren, Longbin, Long, Xiangdong, Li, Jing, He, Peng, Lin, Huihui, Cui, Yige, Peng, Xinnan, Shi, Jiwei, Wu, Jie, Zhang, Chun, Zou, Ruqiang, Guillen-Gosalbez, Gonzalo, Perez-Ramirez, Javier, Koh, Ming Joo, Zhu, Ye, Li, Jun, Lu, Jiong

“… Single-atom catalysts (SACs) have well-defined active sites, making them of potential interest for organic synthesis(1-4). However, the architecture of these …”
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A molecular photosensitizer achieves a V oc of 1.24 V enabling highly efficient and stable dye-sensitized solar cells with copper(II/I)-based electrolyte von Zhang, Dan, Stojanovic, Marko, Ren, Yameng, Cao, Yiming, Eickemeyer, Felix T, Socie, Etienne, Vlachopoulos, Nick, Moser, Jacques-E, Zakeeruddin, Shaik M, Hagfeldt, Anders, Grätzel, Michael

“… To develop photosensitizers with high open-circuit photovoltage (V ) is a crucial strategy to enhance the power conversion efficiency (PCE) of co-sensitized …”
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Kinase drug discovery 20 years after imatinib von Cohen, Philip, Cross, Darren, Jänne, Pasi A

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Spin-sate reconfiguration induced by alternating magnetic field for efficient oxygen evolution reaction von Zhou, Gang, Wang, Peifang, Li, Hao, Hu, Bin, Sun, Yan, Huang, Rong, Liu, Lizhe

“… Oxygen evolution reaction (OER) plays a determining role in electrochemical energy conversion devices, but challenges remain due to the lack of effective …”
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The RNA modification N 6 -methyladenosine as a novel regulator of the immune system von Shulman, Ziv, Stern-Ginossar, Noam

“… Protection from harmful pathogens depends on activation of the immune system, which relies on tight regulation of gene expression. Recently, the RNA …”
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Ion sieving by a two-dimensional Ti3C2T x alginate lamellar membrane with stable interlayer spacing von Jin Wang, Zhijie Zhang, Jiani Zhu, Mengtao Tian, Shuchang Zheng, Fudi Wang, Xudong Wang, Lei Wang

“… Two dimensional lamellar membranes are attractive for anomalous water and ion transfer, but performance is hindered by swelling. Here, the authors stabilize a …”
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Anomalous transport due to Weyl fermions in the chiral antiferromagnets Mn3 X, X = Sn, Ge von Taishi Chen, Takahiro Tomita, Susumu Minami, Mingxuan Fu, Takashi Koretsune, Motoharu Kitatani, Ikhlas Muhammad, Daisuke Nishio-Hamane, Rieko Ishii, Fumiyuki Ishii, Ryotaro Arita, Satoru Nakatsuji

“… The large anomalous Hall (AHE) and anomalous Nernst effects (ANE) in antiferromagnets Mn3Sn/Mn3Ge are considered fingerprints of Weyl nodes residing near the …”
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e g occupancy as an effective descriptor for the catalytic activity of perovskite oxide-based peroxidase mimics von Wang, Xiaoyu, Gao, Xuejiao J, Qin, Li, Wang, Changda, Song, Li, Zhou, Yong-Ning, Zhu, Guoyin, Cao, Wen, Lin, Shichao, Zhou, Liqi, Wang, Kang, Zhang, Huigang, Jin, Zhong, Wang, Peng, Gao, Xingfa, Wei, Hui

“… A peroxidase catalyzes the oxidation of a substrate with a peroxide. The search for peroxidase-like and other enzyme-like nanomaterials (called nanozymes) …”
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Role of mobile genetic elements in the global dissemination of the carbapenem resistance gene bla NDM von Acman, Mislav, Wang, Ruobing, van Dorp, Lucy, Shaw, Liam P, Wang, Qi, Luhmann, Nina, Yin, Yuyao, Sun, Shijun, Chen, Hongbin, Wang, Hui, Balloux, Francois

“… The mobile resistance gene bla encodes the NDM enzyme which hydrolyses carbapenems, a class of antibiotics used to treat some of the most severe bacterial …”
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GWAS of lifetime cannabis use reveals new risk loci, genetic overlap with psychiatric traits, and a causal influence of schizophrenia von Pasman, Joëlle A, Verweij, Karin J H, Gerring, Zachary, Stringer, Sven, Sanchez-Roige, Sandra, Treur, Jorien L, Abdellaoui, Abdel, Nivard, Michel G, Baselmans, Bart M L, Ong, Jue-Sheng, Ip, Hill F, van der Zee, Matthijs D, Bartels, Meike, Day, Felix R, Fontanillas, Pierre, Elson, Sarah L, de Wit, Harriet, Davis, Lea K, MacKillop, James, Derringer, Jaime L, Branje, Susan J T, Hartman, Catharina A, Heath, Andrew C, van Lier, Pol A C, Madden, Pamela A F, Mägi, Reedik, Meeus, Wim, Montgomery, Grant W, Oldehinkel, A J, Pausova, Zdenka, Ramos-Quiroga, Josep A, Paus, Tomas, Ribases, Marta, Kaprio, Jaakko, Boks, Marco P M, Bell, Jordana T, Spector, Tim D, Gelernter, Joel, Boomsma, Dorret I, Martin, Nicholas G, MacGregor, Stuart, Perry, John R B, Palmer, Abraham A, Posthuma, Danielle, Munafò, Marcus R, Gillespie, Nathan A, Derks, Eske M, Vink, Jacqueline M

“… Cannabis use is a heritable trait that has been associated with adverse mental health outcomes. In the largest genome-wide association study (GWAS) for …”
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Pressure-induced monotonic enhancement of T c to over 30 K in superconducting Pr0.82Sr0.18NiO2 thin films von N. N. Wang, M. W. Yang, Z. Yang, K. Y. Chen, H. Zhang, Q. H. Zhang, Z. H. Zhu, Y. Uwatoko, L. Gu, X. L. Dong, J. P. Sun, K. J. Jin, J.-G. Cheng

“… Despite much recent effort, the highest reported T c of the infinite-layer nickelates remains lower than 15 K. Here, the authors apply pressure to …”
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A new global ice sheet reconstruction for the past 80000 years von Gowan, Evan J., Zhang, Xu, Khosravi, Sara, Rovere, Alessio, Stocchi, Paolo, Hughes, Anna L. C., Gyllencreutz, Richard, Mangerud, Jan, Svendsen, John-Inge, Lohmann, Gerrit

“… The evolution of past global ice sheets is highly uncertain. One example is the missing ice problem during the Last Glacial Maximum (LGM, 26000-19000 years …”
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Skeletal editing of pyridines through atom-pair swap from CN to CC von Cheng, Qiang, Bhattacharya, Debkanta, Haring, Malte, Cao, Hui, Mueck-Lichtenfeld, Christian, Studer, Armido

“… Skeletal editing is a straightforward synthetic strategy for precise substitution or rearrangement of atoms in core ring structures of complex molecules; it …”
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