Search Results - Key words. computational and structural complexity
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LCRAnnotationsDB: a database of low complexity regions functional and structural annotations
ISSN: 1471-2164, 1471-2164Published: London BioMed Central 27.12.2024Published in BMC genomics (27.12.2024)“…Low Complexity Regions (LCRs) are segments of proteins with a low diversity of amino acid composition…”
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Increased self-focus and diminished informativity: referential and structural properties of narrative speech production in borderline personality disorder
ISSN: 2051-6673, 2051-6673Published: London BioMed Central 17.11.2025Published in Borderline personality disorder and emotion dysregulation (17.11.2025)“…Background Narrative speech production (NSP), i.e., the conceptualization, linguistic formulation, and articulation of a story, is a multifaceted process…”
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Multi-Disciplinary Characteristics of Double-Skin Facades for Computational Modeling Perspective and Practical Design Considerations
ISSN: 2075-5309, 2075-5309Published: Basel MDPI AG 01.10.2022Published in Buildings (Basel) (01.10.2022)“…Vertical building enclosures known as Double-skin façades (DSFs) have become recognized as a promising façade type for buildings that place emphasis on…”
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Nothing in evolution makes sense except in the light of code biology
ISSN: 0303-2647, 1872-8324, 1872-8324Published: Ireland Elsevier B.V 01.07.2023Published in BioSystems (01.07.2023)“… In other words, living entities and non-living things behave like rules and laws, respectively, but this important distinction is rarely considered in current evolutionary theory…”
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Product, process and methodology systematization to handle structural and computational complexity in product realization
ISSN: 1092-7026, 1099-1743Published: Chichester, UK John Wiley & Sons, Ltd 01.11.2001Published in Systems research and behavioral science (01.11.2001)“…This paper establishes a concept for Product, Process, and Methodology (PPM) systematization to handle both structural complexity…”
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Single document keyword extraction via quantifying higher-order structural features of word co-occurrence graph
ISSN: 0885-2308, 1095-8363Published: Elsevier Ltd 01.09.2019Published in Computer speech & language (01.09.2019)“…•A new graph-based measure for keyword extraction is proposed, by lever- aging higher-order structural features (e.g. motifs…”
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Large-scale prediction of activity cliffs using machine and deep learning methods of increasing complexity
ISSN: 1758-2946, 1758-2946Published: Cham Springer International Publishing 07.01.2023Published in Journal of cheminformatics (07.01.2023)“…Activity cliffs (AC) are formed by pairs of structural analogues that are active against the same target but have a large difference in potency…”
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The effects of model complexity and size on metabolic flux distribution and control: case study in Escherichia coli
ISSN: 1471-2105, 1471-2105Published: London BioMed Central 20.03.2021Published in BMC bioinformatics (20.03.2021)“… However, it is important to study how network complexity affects conclusions derived from large-scale kinetic models built around consistently reduced models before we can apply them to study biological systems…”
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On the potential of computational methods and numerical simulation in ice mechanics
ISSN: 1757-899X, 1757-8981, 1757-899XPublished: Bristol IOP Publishing 01.06.2010Published in IOP conference series. Materials Science and Engineering (01.06.2010)“…, especially for irregular structural configurations. The paper explains the complexity of ice as a material in computational mechanics terms…”
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RintC: fast and accuracy-aware decomposition of distributions of RNA secondary structures with extended logsumexp
ISSN: 1471-2105, 1471-2105Published: London BioMed Central 24.05.2020Published in BMC bioinformatics (24.05.2020)“… Existing methods, however, are not applicable to long RNAs owing to their high computational complexity…”
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Assessing structural variation in a personal genome—towards a human reference diploid genome
ISSN: 1471-2164, 1471-2164Published: London BioMed Central 11.04.2015Published in BMC genomics (11.04.2015)“… While multiple data types and methods are available to detect these structural variants (SVs), they remain less characterized than smaller variants because of SV diversity, complexity, and size…”
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Dependency Grammar Approach to the Syntactic Complexity in the Discourse of Alzheimer Patients
ISSN: 2076-328X, 2076-328XPublished: Switzerland MDPI AG 29.09.2025Published in Behavioral sciences (29.09.2025)“…This study aims to investigate the syntactic complexity in individuals with Alzheimer’s disease (AD) by conducting a comprehensive analysis that incorporates mean dependency distance…”
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Computationally efficient multi-sample flow cytometry data analysis using Gaussian mixture models
ISSN: 1471-2105, 1471-2105Published: London BioMed Central 23.10.2025Published in BMC bioinformatics (23.10.2025)“… direct comparison of cell populations across the data samples. The multi-sample approach to statistical mixture modeling has been explored in a number of reports, mostly within a Bayesian framework and with high computational complexity…”
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Using pseudo amino acid composition to predict transmembrane regions in protein: cellular automata and Lempel-Ziv complexity
ISSN: 0939-4451, 1438-2199, 1438-2199Published: Vienna Vienna : Springer-Verlag 2008Published in Amino acids (2008)“…Transmembrane (TM) proteins represent about 20-30% of the protein sequences in higher eukaryotes, playing important roles across a range of cellular functions…”
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From Factors to Actors: Computational Sociology and Agent-Based Modeling
ISSN: 0360-0572, 1545-2115Published: Palo Alto, CA Annual Reviews 01.01.2002Published in Annual review of sociology (01.01.2002)“…Sociologists often model social processes as interactions among variables. We review an alternative approach that models social life as interactions among…”
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Benchmarks for interpretation of QSAR models
ISSN: 1758-2946, 1758-2946Published: Cham Springer International Publishing 26.05.2021Published in Journal of cheminformatics (26.05.2021)“…Interpretation of QSAR models is useful to understand the complex nature of biological or physicochemical processes, guide structural optimization or perform knowledge-based validation of QSAR models…”
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Direct coupling analysis and the attention mechanism
ISSN: 1471-2105, 1471-2105Published: England BioMed Central Ltd 06.02.2025Published in BMC bioinformatics (06.02.2025)“… For this reason, being able to predict their structure from the amino acid sequence has been and still is a phenomenal computational challenge that the introduction of AlphaFold solved with unprecedented accuracy…”
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Genomic and structural analysis of genes involved in epigenetic regulations of diffuse large B cell lymphoma by computational approaches
ISSN: 2587-2362Published: KARE Publishing 01.09.2025Published in International Journal of Medical Biochemistry (01.09.2025)“…), various issues, including resistance and toxicity, are among the main concerns. Additional contributor to the poor prognosis is genomic complexity of DLBCL, where high number of mutations are associated with the DLBCL pathogenesis…”
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Structural prediction of protein models using distance restraints derived from cross-linking mass spectrometry data
ISSN: 1754-2189, 1750-2799, 1750-2799Published: England Nature Publishing Group 01.03.2018Published in Nature protocols (01.03.2018)“…This protocol describes a workflow for creating structural models of proteins or protein complexes using distance restraints derived from cross-linking mass spectrometry experiments…”
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Comparative study of whole exome sequencing-based copy number variation detection tools
ISSN: 1471-2105, 1471-2105Published: London BioMed Central 05.03.2020Published in BMC bioinformatics (05.03.2020)“…Background With the rapid development of whole exome sequencing (WES), an increasing number of tools are being proposed for copy number variation (CNV)…”
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