Search Results - Current Progress in Bioinformatics 2016 Papers

A survey of current trends in computational drug repositioning by Li, Jiao, Zheng, Si, Chen, Bin, Butte, Atul J., Swamidass, S. Joshua, Lu, Zhiyong

“…Computational drug repositioning or repurposing is a promising and efficient tool for discovering new uses from existing drugs and holds the great potential…”
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Recent Advances and Emerging Applications in Text and Data Mining for Biomedical Discovery by Gonzalez, Graciela H., Tahsin, Tasnia, Goodale, Britton C., Greene, Anna C., Greene, Casey S.

“…Precision medicine will revolutionize the way we treat and prevent disease. A major barrier to the implementation of precision medicine that clinicians and…”
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Crowdsourcing in biomedicine: challenges and opportunities by Khare, Ritu, Good, Benjamin M., Leaman, Robert, Su, Andrew I., Lu, Zhiyong

“…The use of crowdsourcing to solve important but complex problems in biomedical and clinical sciences is growing and encompasses a wide variety of approaches…”
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Adapting bioinformatics curricula for big data by Greene, Anna C., Giffin, Kristine A., Greene, Casey S., Moore, Jason H.

“… Computational biologists and bioinformatics scientists are increasingly being asked to use these data to reveal key systems-level properties…”
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Progress and challenges in bioinformatics approaches for enhancer identification by Kleftogiannis, Dimitrios, Kalnis, Panos, Bajic, Vladimir B.

“…Enhancers are cis-acting DNA elements that play critical roles in distal regulation of gene expression. Identifying enhancers is an important step for…”
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DeepEM3D: approaching human-level performance on 3D anisotropic EM image segmentation by Zeng, Tao, Wu, Bian, Ji, Shuiwang

“…Progress in 3D electron microscopy (EM) imaging has greatly facilitated neuroscience research in high-throughput data acquisition…”
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Solving the master equation for Indels by Holmes, Ian H.

“… (BMC Bioinformatics 17:304, 2016); (BMC Bioinformatics 17:397, 2016); (BMC Bioinformatics 17:457, 2016…”
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The Top 100 Articles in the Medical Informatics: a Bibliometric Analysis by Nadri, Hamed, Rahimi, Bahlol, Timpka, Toomas, Sedghi, Shahram

“…The number of citations that a research paper receives can be used as a measure of its scientific impact…”
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Explainable artificial intelligence for medical imaging systems using deep learning: a comprehensive review by Houssein, Essam H., Gamal, Amr M., Younis, Eman M. G., Mohamed, Ebtsam

“…The world recently witnessed strong growth in artificial intelligence (AI) use across various sectors, driven by the digital revolution that began in 2016…”
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Editorial: Protecting privacy in neuroimaging analysis: balancing data sharing and privacy preservation by Mehmood, Rashid, Lazar, Mariana, Liang, Xiaohui, Corchado, Juan M., See, Simon

“… challenges (Saponaro et al. 2022;Cali et al. 2023;Li et al. 2020;Zou et al. 2024;Acar et al. 2023). As scientific progress depends on data sharing and collaboration…”
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Harmonizing AI governance regulations and neuroinformatics: perspectives on privacy and data sharing by Alsaigh, Roba, Mehmood, Rashid, Katib, Iyad, Liang, Xiaohui, Alshanqiti, Abdullah, Corchado, Juan M., See, Simon

“…). This paper explores the urgent need to harmonize AI governance regulations with neuroinformatics practices, with a specific focus on the domains of data sharing…”
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STRUM: structure-based prediction of protein stability changes upon single-point mutation by Quan, Lijun, Lv, Qiang, Zhang, Yang

“…; but most require features from experimental structure. Given the fast progress in protein structure prediction, this work explores the possibility to improve the mutation-induced stability change prediction using low-resolution structure modeling. Results…”
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Computational prospecting the great viral unknown by Hurwitz, Bonnie L., U'Ren, Jana M., Youens-Clark, Ken

“…Bacteriophages play an important role in host-driven biological processes by controlling bacterial population size, horizontally transferring genes between…”
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Critical assessment of methods of protein structure prediction (CASP)—Round XII by Moult, John, Fidelis, Krzysztof, Kryshtafovych, Andriy, Schwede, Torsten, Tramontano, Anna

“… Analysis of the submitted structures by independent assessors provides a comprehensive picture of the capabilities of current methods, and allows progress to be identified…”
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A new data science research program: evaluation, metrology, standards, and community outreach by Dorr, Bonnie J., Greenberg, Craig S., Fontana, Peter, Przybocki, Mark, Le Bras, Marion, Ploehn, Cathryn, Aulov, Oleg, Michel, Martial, Golden, E. Jim, Chang, Wo

“…This article examines foundational issues in data science including current challenges, basic research questions, and expected advances, as the basis for a new data science research program (DSRP…”
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Do Read Errors Matter for Genome Assembly? by Shomorony, Ilan, Courtade, Thomas, Tse, David

“…While most current high-throughput DNA sequencing technologies generate short reads with low error rates, emerging sequencing technologies generate long reads with high error rates…”
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Recurrent and pathological gene fusions in breast cancer: current advances in genomic discovery and clinical implications by Veeraraghavan, Jamunarani, Ma, Jiacheng, Hu, Yiheng, Wang, Xiao-Song

“… and the advancement of deep sequencing technologies. With the progress in deep sequencing studies of breast cancer transcriptomes and genomes, the discovery of recurrent and pathological gene fusions in breast cancer is on the…”
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Network Pharmacology-based Approaches Capture Essence of Chinese Herbal Medicines by Zhang, Yan-qiong, Mao, Xia, Guo, Qiu-yan, Lin, Na, Li, Shao

“… With the rapid progress in bioinformatics, systems biology, and polypharmacology…”
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Randomized, placebo-controlled trial evaluating the safety of one-year administration of green tea catechins by Kumar, Nagi B, Pow-Sang, Julio, Spiess, Philippe E, Park, Jong, Salup, Raoul, Williams, Christopher R, Parnes, Howard, Schell, Michael J

“… These requirements have impeded recruitment and retention of subjects in chemoprevention trials and subsequent progress in agent development efforts…”
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Enhancement of Plant Productivity in the Post-Genomics Era by Thao, Nguyen Phuong, Tran, Lam-Son Phan

“…Obtaining high plant yield is not always achievable in agricultural activity as it is determined by various factors, including cultivar quality, nutrient and…”
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