Search Results - (tissues OR issue) array analysis - methods

Defining the human kidney N‐glycome in normal and cancer tissues using MALDI imaging mass spectrometry by Drake, Richard R., McDowell, Colin, West, Connor, David, Fred, Powers, Thomas W., Nowling, Tamara, Bruner, Evelyn, Mehta, Anand S., Angel, Peggi M., Marlow, Laura A., Tun, Han W., Copland, John A.

“…‐fixed clinical ccRCC specimens and tissue microarrays. Regions of normal kidney tissue samples were also evaluated for N‐linked glycan…”
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Production of Tissue Microarrays, Immunohistochemistry Staining and Digitalization Within the Human Protein Atlas by Kampf, Caroline, Olsson, IngMarie, Ryberg, Urban, Sjöstedt, Evelina, Pontén, Fredrik

“…The tissue microarray (TMA) technology provides the means for high-throughput analysis of multiple tissues and cells…”
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Tissue matrix arrays for high-throughput screening and systems analysis of cell function by Beachley, Vince Z, Wolf, Matthew T, Sadtler, Kaitlyn, Manda, Srikanth S, Jacobs, Heather, Blatchley, Michael R, Bader, Joel S, Pandey, Akhilesh, Pardoll, Drew, Elisseeff, Jennifer H

“… We validated the 2D and 3D arrays as representative of the in vivo microenvironment by means of quantitative analysis of tissue-specific cellular responses, including matrix production, adhesion…”
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Inter-tissue glycan heterogeneity: site-specific glycoform analysis of mouse tissue N-glycoproteomes using MS1-based glycopeptide detection method assisted by lectin microarray: Inter-tissue glycan heterogeneity: site-specific glycoform analysis of mouse tissue N-glycoproteomes using MS1-based glycopeptide detection method assisted by lectin microarray by Nagai-Okatani, Chiaki, Tomioka, Azusa, Tominaga, Daisuke, Sakaue, Hiroaki, Kuno, Atsushi, Kaji, Hiroyuki

“…” of samples, we previously introduced an MS1-based glycopeptide detection method, “Glyco-RIDGE.” Here, to elucidate inter-tissue glycan heterogeneities, this estimation…”
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Integrating microarray-based spatial transcriptomics and single-cell RNA-seq reveals tissue architecture in pancreatic ductal adenocarcinomas by Moncada, Reuben, Barkley, Dalia, Wagner, Florian, Chiodin, Marta, Devlin, Joseph C, Baron, Maayan, Hajdu, Cristina H, Simeone, Diane M, Yanai, Itai

“…, with scRNA-Seq generated from the same sample. To annotate the precise cellular composition of distinct tissue regions, we introduce a method for multimodal intersection analysis…”
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Next-generation tissue microarray (ngTMA) Protocol for biomarker studies by Zlobec, Inti, Suter, Guido, Perren, Aurel, Lugli, Alessandro

“…Biomarker research relies on tissue microarrays (TMA). TMAs are produced by repeated transfer of small tissue cores from a 'donor' block into a 'recipient' block and then used for a variety of biomarker applications…”
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Parallel Analyses by Mass Spectrometry (MS) and Reverse Phase Protein Array (RPPA) Reveal Complementary Proteomic Profiles in Triple‐Negative Breast Cancer (TNBC) Patient Tissues and Cell Cultures by Wang, Nan, Zhu, Yiying, Wang, Lianshui, Dai, Wenshuang, Hu, Taobo, Song, Zhentao, Li, Xia, Zhang, Qi, Ma, Jianfei, Xia, Qianghua, Li, Jin, Liu, Yiqiang, Long, Mengping, Ding, Zhiyong

“… In this study, we employed two widely used proteomic technologies, mass spectrometry (MS) and reverse phase protein array (RPPA…”
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Fabrication and use of silicon hollow-needle arrays to achieve tissue nanotransfection in mouse tissue in vivo by Xuan, Yi, Ghatak, Subhadip, Clark, Andrew, Li, Zhigang, Khanna, Savita, Pak, Dongmin, Agarwal, Mangilal, Roy, Sashwati, Duda, Peter, Sen, Chandan K.

“…Tissue nanotransfection (TNT) is an electromotive gene transfer technology that was developed to achieve tissue reprogramming in vivo…”
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Comparing computer-generated and pathologist-generated tumour segmentations for immunohistochemical scoring of breast tissue microarrays by Akbar, Shazia, Jordan, Lee B, Purdie, Colin A, Thompson, Alastair M, McKenna, Stephen J

“…Background: Tissue microarrays (TMAs) have become a valuable resource for biomarker expression in translational research…”
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Overview of transcriptomic analysis of all human proteases, non-proteolytic homologs and inhibitors: Organ, tissue and ovarian cancer cell line expression profiling of the human protease degradome by the CLIP-CHIP™ DNA microarray by Kappelhoff, Reinhild, Puente, Xose S., Wilson, Claire H., Seth, Arun, López-Otín, Carlos, Overall, Christopher M.

“…The protease degradome is defined as the complete repertoire of proteases and inhibitors, and their nonfunctional homologs present in a cell, tissue or organism at any given time…”
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Tissue Microarrays by Dancau, Ana-Maria, Simon, Ronald, Mirlacher, Martina, Sauter, Guido

“… The tissue microarray technology greatly facilitates such analysis. In this method minute tissue samples (typically 0.6 mm in diameter…”
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High-definition spatial transcriptomics for in situ tissue profiling by Vickovic, Sanja, Eraslan, Gökcen, Salmén, Fredrik, Klughammer, Johanna, Stenbeck, Linnea, Schapiro, Denis, Äijö, Tarmo, Bonneau, Richard, Bergenstråhle, Ludvig, Navarro, José Fernandéz, Gould, Joshua, Griffin, Gabriel K, Borg, Åke, Ronaghi, Mostafa, Frisén, Jonas, Lundeberg, Joakim, Regev, Aviv, Ståhl, Patrik L

“…Spatial and molecular characteristics determine tissue function, yet high-resolution methods to capture both concurrently are lacking…”
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Glycan profiling analysis using evanescent-field fluorescence-assisted lectin array: Importance of sugar recognition for cellular uptake of exosomes from mesenchymal stem cells by Shimoda, Asako, Tahara, Yoshiro, Sawada, Shin-ichi, Sasaki, Yoshihiro, Akiyoshi, Kazunari

“… them. To shed light on these issues, we collected exosomes from mesenchymal stem cells (MSCs) derived from human adipose tissue for glycan profiling using evanescent-field fluorescence-assisted lectin array as well as analysis of their uptake in vivo…”
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Novel molecular tumour classification using MALDI-mass spectrometry imaging of tissue micro-array by Djidja, Marie-Claude, Claude, Emmanuelle, Snel, Marten F, Francese, Simona, Scriven, Peter, Carolan, Vikki, Clench, Malcolm R

“…The development of tissue micro-array (TMA) technologies provides insights into high-throughput analysis of proteomics patterns from a large number of archived tumour samples…”
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Programmed death-ligand 1 expression influenced by tissue sample size. Scoring based on tissue microarrays’ and cross-validation with resections, in patients with, stage I–III, non-small cell lung carcinoma of the European Thoracic Oncology Platform Lungscape cohort by Thunnissen, Erik, Kerr, Keith M., Dafni, Urania, Bubendorf, Lukas, Finn, Stephen P., Soltermann, Alex, Biernat, Wojciech, Cheney, Richard, Verbeken, Erik, Warth, Arne, Marchetti, Antonio, Speel, Ernst-Jan M., Pokharel, Saraswati, Quinn, Anne Marie, Monkhorst, Kim, Navarro, Atilio, Madsen, Line Bille, Tsourti, Zoi, Geiger, Thomas, Kammler, Roswitha, Peters, Solange, Stahel, Rolf A.

“… PD-L1 expression was assessed via immunohistochemistry on tissue microarrays (up to four cores per case…”
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A flexible catheter-based sensor array for upper airway soft tissues pressure monitoring by Shang, Jiang, Ma, Xiaoxiao, Zou, Peikai, Huang, Chenxiao, Lao, Zhechen, Wang, Junhan, Jiang, Tingshu, Fu, Yanzhe, Li, Jiebo, Zhang, Shaoxing, Li, Ruya, Fan, Yubo

“… Here, we report a catheter-based flexible pressure sensor array that continuously monitors soft tissue pressure in the upper airway and facilitates at the millimeter level…”
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Reproducible workflow for multiplexed deep-scale proteome and phosphoproteome analysis of tumor tissues by liquid chromatography-mass spectrometry by Mertins, Philipp, Tang, Lauren C, Krug, Karsten, Clark, David J, Gritsenko, Marina A, Chen, Lijun, Clauser, Karl R, Clauss, Therese R, Shah, Punit, Gillette, Michael A, Petyuk, Vladislav A, Thomas, Stefani N, Mani, D R, Mundt, Filip, Moore, Ronald J, Hu, Yingwei, Zhao, Rui, Schnaubelt, Michael, Keshishian, Hasmik, Monroe, Matthew E, Zhang, Zhen, Udeshi, Namrata D, Mani, Deepak, Davies, Sherri R, Townsend, R Reid, Chan, Daniel W, Smith, Richard D, Zhang, Hui, Liu, Tao, Carr, Steven A

“…Here we present an optimized workflow for global proteome and phosphoproteome analysis of tissues or cell lines that uses isobaric tags (TMT (tandem mass tags)-10…”
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Identification of reference genes for RT-qPCR expression analysis in Arabidopsis and tomato seeds by Dekkers, Bas J W, Willems, Leo, Bassel, George W, van Bolderen-Veldkamp, R P Marieke, Ligterink, Wilco, Hilhorst, Henk W M, Bentsink, Leónie

“… Reverse transcription-quantitative real-time PCR (RT-qPCR) is the preferred method for targeted gene expression measurements because of its sensitivity and reproducibility…”
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Digital pathology and image analysis in tissue biomarker research by Hamilton, Peter W., Bankhead, Peter, Wang, Yinhai, Hutchinson, Ryan, Kieran, Declan, McArt, Darragh G., James, Jacqueline, Salto-Tellez, Manuel

“… A variety of image analysis applications are reviewed including nuclear morphometry and tissue architecture analysis, but with emphasis on immunohistochemistry and fluorescence analysis of tissue biomarkers…”
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High‐throughput MALDI‐MSI metabolite analysis of plant tissue microarrays by Huang, Hangjun, Liu, Haiqiang, Ma, Weiwei, Qin, Liang, Chen, Lulu, Guo, Hua, Xu, Hualei, Li, Jinrong, Yang, Chenyu, Hu, Hao, Wu, Ran, Chen, Difan, Feng, Jinchao, Zhou, Yijun, Wang, Junli, Wang, Xiaodong

“…‐based plant tissue microarray (MALDI‐MSI‐PTMA), was successfully developed for high‐throughput metabolite detection and imaging from plant tissues…”
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