Výsledky vyhledávání - (tissue OR issues) array analysis - methods

Tissue matrix arrays for high-throughput screening and systems analysis of cell function Autor Beachley, Vince Z, Wolf, Matthew T, Sadtler, Kaitlyn, Manda, Srikanth S, Jacobs, Heather, Blatchley, Michael R, Bader, Joel S, Pandey, Akhilesh, Pardoll, Drew, Elisseeff, Jennifer H

“… We validated the 2D and 3D arrays as representative of the in vivo microenvironment by means of quantitative analysis of tissue-specific cellular responses, including matrix production, adhesion…”
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Production of Tissue Microarrays, Immunohistochemistry Staining and Digitalization Within the Human Protein Atlas Autor Kampf, Caroline, Olsson, IngMarie, Ryberg, Urban, Sjöstedt, Evelina, Pontén, Fredrik

“…The tissue microarray (TMA) technology provides the means for high-throughput analysis of multiple tissues and cells…”
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Inter-tissue glycan heterogeneity: site-specific glycoform analysis of mouse tissue N-glycoproteomes using MS1-based glycopeptide detection method assisted by lectin microarray: Inter-tissue glycan heterogeneity: site-specific glycoform analysis of mouse tissue N-glycoproteomes using MS1-based glycopeptide detection method assisted by lectin microarray Autor Nagai-Okatani, Chiaki, Tomioka, Azusa, Tominaga, Daisuke, Sakaue, Hiroaki, Kuno, Atsushi, Kaji, Hiroyuki

“…” of samples, we previously introduced an MS1-based glycopeptide detection method, “Glyco-RIDGE.” Here, to elucidate inter-tissue glycan heterogeneities, this estimation…”
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Defining the human kidney N‐glycome in normal and cancer tissues using MALDI imaging mass spectrometry Autor Drake, Richard R., McDowell, Colin, West, Connor, David, Fred, Powers, Thomas W., Nowling, Tamara, Bruner, Evelyn, Mehta, Anand S., Angel, Peggi M., Marlow, Laura A., Tun, Han W., Copland, John A.

“…‐fixed clinical ccRCC specimens and tissue microarrays. Regions of normal kidney tissue samples were also evaluated for N‐linked glycan…”
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Integrating microarray-based spatial transcriptomics and single-cell RNA-seq reveals tissue architecture in pancreatic ductal adenocarcinomas Autor Moncada, Reuben, Barkley, Dalia, Wagner, Florian, Chiodin, Marta, Devlin, Joseph C, Baron, Maayan, Hajdu, Cristina H, Simeone, Diane M, Yanai, Itai

“…, with scRNA-Seq generated from the same sample. To annotate the precise cellular composition of distinct tissue regions, we introduce a method for multimodal intersection analysis…”
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Next-generation tissue microarray (ngTMA) Protocol for biomarker studies Autor Zlobec, Inti, Suter, Guido, Perren, Aurel, Lugli, Alessandro

“…Biomarker research relies on tissue microarrays (TMA). TMAs are produced by repeated transfer of small tissue cores from a 'donor' block into a 'recipient' block and then used for a variety of biomarker applications…”
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Fabrication and use of silicon hollow-needle arrays to achieve tissue nanotransfection in mouse tissue in vivo Autor Xuan, Yi, Ghatak, Subhadip, Clark, Andrew, Li, Zhigang, Khanna, Savita, Pak, Dongmin, Agarwal, Mangilal, Roy, Sashwati, Duda, Peter, Sen, Chandan K.

“…Tissue nanotransfection (TNT) is an electromotive gene transfer technology that was developed to achieve tissue reprogramming in vivo…”
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Comparing computer-generated and pathologist-generated tumour segmentations for immunohistochemical scoring of breast tissue microarrays Autor Akbar, Shazia, Jordan, Lee B, Purdie, Colin A, Thompson, Alastair M, McKenna, Stephen J

“…Background: Tissue microarrays (TMAs) have become a valuable resource for biomarker expression in translational research…”
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Tissue Microarrays Autor Dancau, Ana-Maria, Simon, Ronald, Mirlacher, Martina, Sauter, Guido

“… The tissue microarray technology greatly facilitates such analysis. In this method minute tissue samples (typically 0.6 mm in diameter…”
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High-definition spatial transcriptomics for in situ tissue profiling Autor Vickovic, Sanja, Eraslan, Gökcen, Salmén, Fredrik, Klughammer, Johanna, Stenbeck, Linnea, Schapiro, Denis, Äijö, Tarmo, Bonneau, Richard, Bergenstråhle, Ludvig, Navarro, José Fernandéz, Gould, Joshua, Griffin, Gabriel K, Borg, Åke, Ronaghi, Mostafa, Frisén, Jonas, Lundeberg, Joakim, Regev, Aviv, Ståhl, Patrik L

“…Spatial and molecular characteristics determine tissue function, yet high-resolution methods to capture both concurrently are lacking…”
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Glycan profiling analysis using evanescent-field fluorescence-assisted lectin array: Importance of sugar recognition for cellular uptake of exosomes from mesenchymal stem cells Autor Shimoda, Asako, Tahara, Yoshiro, Sawada, Shin-ichi, Sasaki, Yoshihiro, Akiyoshi, Kazunari

“… them. To shed light on these issues, we collected exosomes from mesenchymal stem cells (MSCs) derived from human adipose tissue for glycan profiling using evanescent-field fluorescence-assisted lectin array as well as analysis of their uptake in vivo…”
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Overview of transcriptomic analysis of all human proteases, non-proteolytic homologs and inhibitors: Organ, tissue and ovarian cancer cell line expression profiling of the human protease degradome by the CLIP-CHIP™ DNA microarray Autor Kappelhoff, Reinhild, Puente, Xose S., Wilson, Claire H., Seth, Arun, López-Otín, Carlos, Overall, Christopher M.

“…The protease degradome is defined as the complete repertoire of proteases and inhibitors, and their nonfunctional homologs present in a cell, tissue or organism at any given time…”
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Novel molecular tumour classification using MALDI-mass spectrometry imaging of tissue micro-array Autor Djidja, Marie-Claude, Claude, Emmanuelle, Snel, Marten F, Francese, Simona, Scriven, Peter, Carolan, Vikki, Clench, Malcolm R

“…The development of tissue micro-array (TMA) technologies provides insights into high-throughput analysis of proteomics patterns from a large number of archived tumour samples…”
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Parallel Analyses by Mass Spectrometry (MS) and Reverse Phase Protein Array (RPPA) Reveal Complementary Proteomic Profiles in Triple‐Negative Breast Cancer (TNBC) Patient Tissues and Cell Cultures Autor Wang, Nan, Zhu, Yiying, Wang, Lianshui, Dai, Wenshuang, Hu, Taobo, Song, Zhentao, Li, Xia, Zhang, Qi, Ma, Jianfei, Xia, Qianghua, Li, Jin, Liu, Yiqiang, Long, Mengping, Ding, Zhiyong

“… In this study, we employed two widely used proteomic technologies, mass spectrometry (MS) and reverse phase protein array (RPPA…”
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Programmed death-ligand 1 expression influenced by tissue sample size. Scoring based on tissue microarrays’ and cross-validation with resections, in patients with, stage I–III, non-small cell lung carcinoma of the European Thoracic Oncology Platform Lungscape cohort Autor Thunnissen, Erik, Kerr, Keith M., Dafni, Urania, Bubendorf, Lukas, Finn, Stephen P., Soltermann, Alex, Biernat, Wojciech, Cheney, Richard, Verbeken, Erik, Warth, Arne, Marchetti, Antonio, Speel, Ernst-Jan M., Pokharel, Saraswati, Quinn, Anne Marie, Monkhorst, Kim, Navarro, Atilio, Madsen, Line Bille, Tsourti, Zoi, Geiger, Thomas, Kammler, Roswitha, Peters, Solange, Stahel, Rolf A.

“… PD-L1 expression was assessed via immunohistochemistry on tissue microarrays (up to four cores per case…”
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Digital pathology and image analysis in tissue biomarker research Autor Hamilton, Peter W., Bankhead, Peter, Wang, Yinhai, Hutchinson, Ryan, Kieran, Declan, McArt, Darragh G., James, Jacqueline, Salto-Tellez, Manuel

“… A variety of image analysis applications are reviewed including nuclear morphometry and tissue architecture analysis, but with emphasis on immunohistochemistry and fluorescence analysis of tissue biomarkers…”
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Multi-tissue interactions in an integrated three-tissue organ-on-a-chip platform Autor Skardal, Aleksander, Murphy, Sean V., Devarasetty, Mahesh, Mead, Ivy, Kang, Hyun-Wook, Seol, Young-Joon, Shrike Zhang, Yu, Shin, Su-Ryon, Zhao, Liang, Aleman, Julio, Hall, Adam R., Shupe, Thomas D., Kleensang, Andre, Dokmeci, Mehmet R., Jin Lee, Sang, Jackson, John D., Yoo, James J., Hartung, Thomas, Khademhosseini, Ali, Soker, Shay, Bishop, Colin E., Atala, Anthony

“… One reason for such poor translation from drug candidate to successful use is a lack of model systems that accurately recapitulate normal tissue function of human organs and their response to drug compounds…”
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High‐throughput MALDI‐MSI metabolite analysis of plant tissue microarrays Autor Huang, Hangjun, Liu, Haiqiang, Ma, Weiwei, Qin, Liang, Chen, Lulu, Guo, Hua, Xu, Hualei, Li, Jinrong, Yang, Chenyu, Hu, Hao, Wu, Ran, Chen, Difan, Feng, Jinchao, Zhou, Yijun, Wang, Junli, Wang, Xiaodong

“…‐based plant tissue microarray (MALDI‐MSI‐PTMA), was successfully developed for high‐throughput metabolite detection and imaging from plant tissues…”
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Systematic evaluation of RNA quality, microarray data reliability and pathway analysis in fresh, fresh frozen and formalin-fixed paraffin-embedded tissue samples Autor Wimmer, Isabella, Tröscher, Anna R., Brunner, Florian, Rubino, Stephen J., Bien, Christian G., Weiner, Howard L., Lassmann, Hans, Bauer, Jan

“… Here, we assessed feasibility and reliability of microarray studies analysing transcriptome data from fresh, fresh-frozen (FF) and FFPE tissues…”
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Automated Gleason grading of prostate cancer tissue microarrays via deep learning Autor Arvaniti, Eirini, Fricker, Kim S., Moret, Michael, Rupp, Niels, Hermanns, Thomas, Fankhauser, Christian, Wey, Norbert, Wild, Peter J., Rüschoff, Jan H., Claassen, Manfred

“… grading of prostate cancer tissue microarrays with Hematoxylin and Eosin (H&E) staining. Our system was trained using detailed Gleason annotations on a discovery…”
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