Výsledky vyhledávání - "post-translational modifications"

The evolution of post-translational modifications Autor Bradley, David

“…Post-translational modifications (PTMs) are chemical modifications that can regulate the activity and function of proteins…”
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Post‐translational modifications of histones: Mechanisms, biological functions, and therapeutic targets Autor Liu, Ruiqi, Wu, Jiajun, Guo, Haiwei, Yao, Weiping, Li, Shuang, Lu, Yanwei, Jia, Yongshi, Liang, Xiaodong, Tang, Jianming, Zhang, Haibo

“…Histones are DNA‐binding basic proteins found in chromosomes. After the histone translation, its amino tail undergoes various modifications, such as…”
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Simplicity is the Ultimate Sophistication—Crosstalk of Post-translational Modifications on the RNA Polymerase II Autor Venkat Ramani, Mukesh Kumar, Yang, Wanjie, Irani, Seema, Zhang, Yan

“…, and termination, and mRNA processing. These distinct facets of the transcription cycle rely on specific post-translational modifications…”
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TDP-43 post-translational modifications in health and disease Autor Buratti, Emanuele

“…: This review aims to specifically cover the post-translational modifications (PTMs) that can affect TDP-43 function and cellular status both in health and disease…”
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Regulation of DELLA Proteins by Post-translational Modifications Autor Blanco-Touri��n, Noel, Serrano-Mislata, Antonio, Alabad�, David

“… Moreover, results gathered during recent years indicate that other post-translational modifications…”
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Unconventional post-translational modifications in immunological signaling Autor Mowen, Kerri A, David, Michael

“…Immune system proteins are subject to numerous post-translational modifications. In this Focus Review, Mowen and David describe the key 'non-conventional…”
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Post-translational modifications of tubulin: pathways to functional diversity of microtubules Autor Song, Yuyu, Brady, Scott T.

“…•PTMs vary with time, cell type, subcellular compartment, and physiological state. Tubulin and microtubules are subject to a remarkable number of post-translational modifications…”
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Oxidative post‐translational modifications of plant antioxidant systems under environmental stress Autor Jiménez, Ana, Martí, María Carmen, Sevilla, Francisca

“…Plants are often subject to environmental challenges posed by abiotic and biotic stresses, which are increasing under the current climate change conditions, provoking a loss in crop yield worldwide…”
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Integrating deep learning for post-translational modifications crosstalk on Hsp90 and drug binding Autor Heritz, Jennifer A., Meluni, Katherine A., Backe, Sarah J., Cayaban, Sara J., Wengert, Laura A., Kunz, Meik, Woodford, Mark R., Bourboulia, Dimitra, Mollapour, Mehdi

“…Post-translational modification (PTM) of proteins regulates cellular proteostasis by expanding protein functional diversity…”
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Post-translational modifications of the progesterone receptors Autor Abdel-Hafiz, Hany A., Horwitz, Kathryn B.

“…•Progesterone receptors (PR) are subject to posttranslational modifications (PTM).•PTMs include phosphorylation, ubiquitination, acetylation and SUMOylation…”
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Mass spectrometric quantification of histone post-translational modifications by a hybrid chemical labeling method Autor Maile, Tobias M, Izrael-Tomasevic, Anita, Cheung, Tommy, Guler, Gulfem D, Tindell, Charles, Masselot, Alexandre, Liang, Jun, Zhao, Feng, Trojer, Patrick, Classon, Marie, Arnott, David

“…Mass spectrometry is a powerful alternative to antibody-based methods for the analysis of histone post-translational modifications (marks…”
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Post-translational modifications regulate microtubule function Autor Westermann, Stefan, Weber, Klaus

“… With the exception of acetylation, the post-translational modifications of microtubules — that is, detyrosination/tyrosination, formation…”
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Post translational modifications at the verge of plant-geminivirus interaction Autor Prasad, Ashish, Sharma, Shambhavi, Prasad, Manoj

“… Post-translational modifications (PTMs) are covalent modifications of proteins that have a drastic effect on their conformation, stability and function…”
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The Role of Post-Translational Modifications on the Structure and Function of Tau Protein Autor Ye, Haiqiong, Han, Yue, Li, Ping, Su, Zhengding, Huang, Yongqi

“…Involving addition of chemical groups or protein units to specific residues of the target protein, post-translational modifications (PTMs…”
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Malondialdehyde-Induced Post-translational Modifications in Hemoglobin of Smokers by NanoLC-NSI/MS/MS Analysis Autor Chen, Hauh-Jyun Candy, Chen, Chau-Yi, Fang, Ya-Hsuan, Hung, Kai-Wei, Wu, Deng-Chyang

“… Post-translational modifications of blood hemoglobin can serve as biomarkers for exposure to chemicals…”
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Post-Translational Modifications of the Werner Syndrome Protein WRN Autor Machwe, Amrita, Orren, David K

“… In this review, we highlight the post-translational modifications of WRN, the protein whose function is lacking in individuals with Werner syndrome…”
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Targeting p38 MAP kinase signaling in cancer through post-translational modifications Autor Zou, Xiao, Blank, Michael

“… An increasing number of studies showed that p38 signaling is subject to regulation by a variety of post-translational modifications (PTMs…”
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Regulation of the cardiac Na+ channel NaV1.5 by post-translational modifications Autor Marionneau, Céline, Abriel, Hugues

“…The cardiac voltage-gated Na+ channel, NaV1.5, is responsible for the upstroke of the action potential in cardiomyocytes and for efficient propagation of the…”
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Post-translational modifications of hormone-responsive transcription factors: the next level of regulation Autor Hill, Kristine

“… Post-translational modifications of proteins are a central feature of the signal transduction pathways that regulate gene transcription in response to hormones…”
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Characterization of Post-translational Modifications of Mitochondrial RNA Polymerase and Mitochondrial Ribosomal Protein L12 Autor Paluch, Katelynn V, Platz, Karlie R, Gross, Matthew, Dodge, Helen, Dittenhafer-Reed, Kristin E

“… The mechanism of this communication is unclear. The mitochondrial proteome, including the transcriptional machinery, is subject to post-translational modifications (PTMs…”
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