Search Results - "info:eu-repo/classification/ddc/576.5"
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Generation of human islet cell type-specific identity genesets
ISSN: 2041-1723, 2041-1723Published: London Nature Publishing Group UK 19.04.2022Published in Nature communications (19.04.2022)“…Generation of surrogate cells with stable functional identities is crucial for developing cell-based therapies. Efforts to produce insulin-secreting…”
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GPR40 activation initiates store-operated Ca2+ entry and potentiates insulin secretion via the IP3R1/STIM1/Orai1 pathway in pancreatic β-cells
ISSN: 2045-2322, 2045-2322Published: London Nature Publishing Group UK 29.10.2019Published in Scientific reports (29.10.2019)“…The long-chain fatty acid receptor GPR40 plays an important role in potentiation of glucose-induced insulin secretion (GIIS) from pancreatic β-cells. Previous…”
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Evolution of genes and genomes on the Drosophila phylogeny
ISSN: 0028-0836, 1476-4687, 1476-4687, 1476-4679Published: England Nature Publishing Group 08.11.2007Published in Nature (08.11.2007)“…Comparative analysis of multiple genomes in a phylogenetic framework dramatically improves the precision and sensitivity of evolutionary inference, producing…”
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Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution. [Erratum: 2005 Feb. 17, v. 433, no. 7027, p. 777.]
ISSN: 0028-0836, 1476-4687, 1476-4687Published: London Nature Publishing Group UK 09.12.2004Published in Nature (London) (09.12.2004)“…We present here a draft genome sequence of the red jungle fowl, Gallus gallus. Because the chicken is a modern descendant of the dinosaurs and the first…”
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Truncating variants in the SHANK1 gene are associated with a spectrum of neurodevelopmental disorders
ISSN: 1098-3600Published: Elsevier BV 01.10.2021Published in Genetics in Medicine (01.10.2021)Get full text
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Involvement of Membrane GRP78 in Trophoblastic Cell Fusion
ISSN: 1932-6203, 1932-6203Published: United States Public Library of Science 09.08.2012Published in PloS one (09.08.2012)“…Glucose-regulated protein 78 (GRP78) is highly expressed in first trimester cytrophoblastic cells (CTBs), especially in syncytiotrophoblast (STB). However, the…”
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Quantification of ortholog losses in insects and vertebrates
ISSN: 1474-760X, 1465-6906, 1474-760X, 1465-6914Published: England BioMed Central 16.11.2007Published in Genome biology (16.11.2007)“…The increasing number of sequenced insect and vertebrate genomes of variable divergence enables refined comparative analyses to quantify the major modes of…”
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Expression, phosphorylation and function of the Rab-GTPase activating protein TBC1D1 in pancreatic beta-cells
ISSN: 0014-5793, 1873-3468, 1873-3468Published: England Elsevier B.V 03.01.2014Published in FEBS letters (03.01.2014)“…•TBC1D1 is expressed in human and rat beta-cells.•TBC1D1 is phosphorylated in response to glucose.•Knockdown of TBC1D1 resulted in increased basal and…”
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Structural Basis of Transcriptional Gene Silencing Mediated by Arabidopsis MOM1
ISSN: 1553-7404, 1553-7390, 1553-7404Published: United States Public Library of Science 01.02.2012Published in PLoS genetics (01.02.2012)“…Shifts between epigenetic states of transcriptional activity are typically correlated with changes in epigenetic marks. However, exceptions to this rule…”
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Deletion of 3 residues from the C-terminus of MCFD2 affects binding to ERGIC-53 and causes combined factor V and factor VIII deficiency
ISSN: 0006-4971Published: United States 01.02.2008Published in Blood (01.02.2008)“…Combined factor V and factor VIII deficiency (F5F8D) is a rare, autosomal recessive coagulation disorder. F5F8D is genetically linked to mutations in the…”
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Hypoxia-Inducible Angiopoietin-2 Expression Is Mimicked by Iodonium Compounds and Occurs in the Rat Brain and Skin in Response to Systemic Hypoxia and Tissue Ischemia
ISSN: 0002-9440, 1525-2191Published: United States Elsevier Inc 01.06.2000Published in The American journal of pathology (01.06.2000)“…Angiopoietins are ligands for the endothelial cell tyrosine kinase receptor Tie-2. Ang-1, the major physiological activator of Tie-2, promotes blood vessel…”
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Expression profiles of urbilaterian genes uniquely shared between honey bee and vertebrates
ISSN: 1471-2164, 1471-2164Published: London Springer Science and Business Media LLC 12.01.2009Published in BMC Genomics (12.01.2009)“…Background Large-scale comparison of metazoan genomes has revealed that a significant fraction of genes of the last common ancestor of Bilateria (Urbilateria)…”
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