Výsledky vyhľadávania - "de Swart, Rik L."

Measles skin rash: Infection of lymphoid and myeloid cells in the dermis precedes viral dissemination to the epidermis Autor Laksono, Brigitta M., Fortugno, Paola, Nijmeijer, Bernadien M., de Vries, Rory D., Cordisco, Sonia, Kuiken, Thijs, Geijtenbeek, Teunis B. H., Duprex, W. Paul, Brancati, Francesco, de Swart, Rik L.

“…Measles is characterized by fever and a maculopapular skin rash, which is accompanied by immune clearance of measles virus (MV)-infected cells…”
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Morbillivirus Infections: An Introduction Autor De Vries, Rory, Duprex, W., De Swart, Rik

“…Research on morbillivirus infections has led to exciting developments in recent years. Global measles vaccination coverage has increased, resulting in a…”
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Early Target Cells of Measles Virus after Aerosol Infection of Non-Human Primates Autor Lemon, Ken, de Vries, Rory D., Mesman, Annelies W., McQuaid, Stephen, van Amerongen, Geert, Yüksel, Selma, Ludlow, Martin, Rennick, Linda J., Kuiken, Thijs, Rima, Bertus K., Geijtenbeek, Teunis B. H., Osterhaus, Albert D. M. E., Duprex, W. Paul, de Swart, Rik L.

“…Measles virus (MV) is highly infectious, and has long been thought to enter the host by infecting epithelial cells of the respiratory tract. However,…”
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Delineating morbillivirus entry, dissemination and airborne transmission by studying in vivo competition of multicolor canine distemper viruses in ferrets Autor de Vries, Rory D., Ludlow, Martin, de Jong, Alwin, Rennick, Linda J., Verburgh, R. Joyce, van Amerongen, Geert, van Riel, Debby, van Run, Peter R. W. A., Herfst, Sander, Kuiken, Thijs, Fouchier, Ron A. M., Osterhaus, Albert D. M. E., de Swart, Rik L., Duprex, W. Paul

“…Identification of cellular receptors and characterization of viral tropism in animal models have vastly improved our understanding of morbillivirus…”
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Modeling the measles paradox reveals the importance of cellular immunity in regulating viral clearance Autor Morris, Sinead E., Yates, Andrew J., de Swart, Rik L., de Vries, Rory D., Mina, Michael J., Nelson, Ashley N., Lin, Wen-Hsuan W., Kouyos, Roger D., Griffin, Diane E., Grenfell, Bryan T.

“…Measles virus (MV) is a highly contagious member of the Morbillivirus genus that remains a major cause of childhood mortality worldwide. Although infection…”
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Long-term measles-induced immunomodulation increases overall childhood infectious disease mortality Autor Mina, Michael J, Metcalf, C Jessica E, de Swart, Rik L, Osterhaus, A D M E, Grenfell, Bryan T

“…Immunosuppression after measles is known to predispose people to opportunistic infections for a period of several weeks to months. Using population-level data,…”
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Intranasal fusion inhibitory lipopeptide prevents direct-contact SARS-CoV-2 transmission in ferrets Autor de Vries, Rory D, Schmitz, Katharina S, Bovier, Francesca T, Predella, Camilla, Khao, Jonathan, Noack, Danny, Haagmans, Bart L, Herfst, Sander, Stearns, Kyle N, Drew-Bear, Jennifer, Biswas, Sudipta, Rockx, Barry, McGill, Gaël, Dorrello, N Valerio, Gellman, Samuel H, Alabi, Christopher A, de Swart, Rik L, Moscona, Anne, Porotto, Matteo

“…Containment of the COVID-19 pandemic requires reducing viral transmission. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is initiated…”
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A Prominent Role for DC-SIGN+ Dendritic Cells in Initiation and Dissemination of Measles Virus Infection in Non-Human Primates Autor Mesman, Annelies W., de Vries, Rory D., McQuaid, Stephen, Duprex, W. Paul, de Swart, Rik L., Geijtenbeek, Teunis B. H.

“…Measles virus (MV) is a highly contagious virus that is transmitted by aerosols. During systemic infection, CD150(+) T and B lymphocytes in blood and lymphoid…”
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Inoculation of raccoons with a wild-type-based recombinant canine distemper virus results in viremia, lymphopenia, fever, and widespread histological lesions Autor Roelofs, Dagmar, Schmitz, Katharina S., van Amerongen, Geert, Rijsbergen, Laurine C., Laksono, Brigitta M., Comvalius, Anouskha D., Nambulli, Sham, Rennick, Linda J., van Run, Peter, Duprex, W. Paul, van den Brand, Judith M. A., de Swart, Rik L., de Vries, Rory D.

“…Raccoons are naturally susceptible to canine distemper virus (CDV) infection and can be a potential source of spill-over events. CDV is a highly contagious…”
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Infection of ferrets with wild type-based recombinant canine distemper virus overwhelms the immune system and causes fatal systemic disease Autor Laksono, Brigitta M., Roelofs, Dagmar, Comvalius, Anouskha D., Schmitz, Katharina S., Rijsbergen, Laurine C., Geers, Daryl, Nambulli, Sham, van Run, Peter, Duprex, W. Paul, van den Brand, Judith M. A., de Vries, Rory D., de Swart, Rik L.

“…Canine distemper virus (CDV) causes systemic infection resulting in severe and often fatal disease in a large spectrum of animal host species. The virus is…”
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Sustained Replication of Synthetic Canine Distemper Virus Defective Genomes In Vitro and In Vivo Autor Tilston-Lunel, Natasha L., Welch, Stephen R., Nambulli, Sham, de Vries, Rory D., Ho, Gregory W., Wentworth, David E., Shabman, Reed, Nichol, Stuart T., Spiropoulou, Christina F., de Swart, Rik L., Rennick, Linda J., Duprex, W. Paul

“…Defective interfering (DI) genomes have long been considered inconvenient artifacts that suppressed viral replication in vitro . However, advances in…”
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The Synthetic Bacterial Lipopeptide Pam3CSK4 Modulates Respiratory Syncytial Virus Infection Independent of TLR Activation Autor Nguyen, D. Tien, de Witte, Lot, Ludlow, Martin, Yüksel, Selma, Wiesmüller, Karl-Heinz, Geijtenbeek, Teunis B. H., Osterhaus, Albert D. M. E., de Swart, Rik L.

“…Respiratory syncytial virus (RSV) is an important cause of acute respiratory disease in infants, immunocompromised subjects and the elderly. However, it is…”
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Needle-free delivery of measles virus vaccine to the lower respiratory tract of non-human primates elicits optimal immunity and protection Autor de Swart, Rik L., de Vries, Rory D., Rennick, Linda J., van Amerongen, Geert, McQuaid, Stephen, Verburgh, R. Joyce, Yüksel, Selma, de Jong, Alwin, Lemon, Ken, Nguyen, D. Tien, Ludlow, Martin, Osterhaus, Albert D. M. E., Duprex, W. Paul

“…Needle-free measles virus vaccination by aerosol inhalation has many potential benefits. The current standard route of vaccination is subcutaneous injection,…”
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Studies into the mechanism of measles-associated immune suppression during a measles outbreak in the Netherlands Autor Laksono, Brigitta M., de Vries, Rory D., Verburgh, R. Joyce, Visser, Eline G., de Jong, Alwin, Fraaij, Pieter L. A., Ruijs, Wilhemina L. M., Nieuwenhuijse, David F., van den Ham, Henk-Jan, Koopmans, Marion P. G., van Zelm, Menno C., Osterhaus, Albert D. M. E., de Swart, Rik L.

“…Measles causes a transient immune suppression, leading to increased susceptibility to opportunistic infections. In experimentally infected non-human primates…”
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In Vitro Modelling of Respiratory Virus Infections in Human Airway Epithelial Cells – A Systematic Review Autor Rijsbergen, Laurine C., van Dijk, Laura L. A., Engel, Maarten F. M., de Vries, Rory D., de Swart, Rik L.

“…Respiratory tract infections (RTI) are a major cause of morbidity and mortality in humans. A large number of RTIs is caused by viruses, often resulting in more…”
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Measles Autor Rota, Paul A., Moss, William J., Takeda, Makoto, de Swart, Rik L., Thompson, Kimberly M., Goodson, James L.

“…Measles is an infectious disease in humans caused by the measles virus (MeV). Before the introduction of an effective measles vaccine, virtually everyone…”
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Measles Immune Suppression: Functional Impairment or Numbers Game? Autor de Vries, Rory D., de Swart, Rik L.

“…  Resolution of MV infection is associated with increased lymphoproliferation [8], [24] and enlargement of lymph nodes [13]. [...]the immune system efficiently…”
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Pathological consequences of systemic measles virus infection Autor Ludlow, Martin, McQuaid, Stephen, Milner, Dan, de Swart, Rik L, Duprex, W Paul

“…The identification of poliovirus receptor‐like 4 (PVRL4) as the second natural receptor for measles virus (MV) has closed a major gap in our understanding of…”
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Complete Genome Sequences of Six Measles Virus Strains Autor Phan, My V. T., Schapendonk, Claudia M. E., Oude Munnink, Bas B., Koopmans, Marion P. G., de Swart, Rik L., Cotten, Matthew

“…Genetic characterization of wild-type measles virus (MV) strains is a critical component of measles surveillance and molecular epidemiology. We have obtained…”
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Species-Specific Colocalization of Middle East Respiratory Syndrome Coronavirus Attachment and Entry Receptors Autor Widagdo, W, Okba, Nisreen M A, Li, Wentao, de Jong, Alwin, de Swart, Rik L, Begeman, Lineke, van den Brand, Judith M A, Bosch, Berend-Jan, Haagmans, Bart L

“…Middle East respiratory syndrome coronavirus (MERS-CoV) uses the S1 domain of its spike protein to bind to dipeptidyl peptidase 4 (DPP4), its functional…”
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