Suchergebnisse - "Zwicky, Katharina"

Visualization of recombination-mediated damage bypass by template switching von Giannattasio, Michele, Zwicky, Katharina, Follonier, Cindy, Foiani, Marco, Lopes, Massimo, Branzei, Dana

“… A combination of two-dimensional gel electrophoresis and EM is used to isolate and characterize multiple template-switching intermediates generated in budding …”
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Replication Fork Slowing and Reversal upon DNA Damage Require PCNA Polyubiquitination and ZRANB3 DNA Translocase Activity von Vujanovic, Marko, Krietsch, Jana, Raso, Maria Chiara, Terraneo, Nastassja, Zellweger, Ralph, Schmid, Jonas A, Taglialatela, Angelo, Huang, Jen-Wei, Holland, Cory L, Zwicky, Katharina, Herrador, Raquel, Jacobs, Heinz, Cortez, David, Ciccia, Alberto, Penengo, Lorenza, Lopes, Massimo

“… DNA damage tolerance during eukaryotic replication is orchestrated by PCNA ubiquitination. While monoubiquitination activates mutagenic translesion synthesis, …”
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Pharmaceutically controlled designer circuit for the treatment of the metabolic syndrome von Ye, Haifeng, Charpin-El Hamri, Ghislaine, Zwicky, Katharina, Christen, Matthias, Folcher, Marc, Fussenegger, Martin

“… Synthetic biology has significantly advanced the design of genetic devices that can reprogram cellular activities and provide novel treatment strategies for …”
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Error-free DNA damage tolerance and sister chromatid proximity during DNA replication rely on the Polα/Primase/Ctf4 Complex von Fumasoni, Marco, Zwicky, Katharina, Vanoli, Fabio, Lopes, Massimo, Branzei, Dana

“… Chromosomal replication is entwined with DNA damage tolerance (DDT) and chromatin structure establishment via elusive mechanisms. Here we examined how specific …”
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Direct visualization of transcription-replication conflicts reveals post-replicative DNA:RNA hybrids von Stoy, Henriette, Zwicky, Katharina, Kuster, Danina, Lang, Kevin S, Krietsch, Jana, Crossley, Magdalena P., Schmid, Jonas A., Cimprich, Karlene A., Merrikh, Houra, Lopes, Massimo

“… Transcription-replication collisions (TRCs) are crucial determinants of genome instability. R-loops were linked to head-on TRCs and proposed to obstruct …”
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Histone Ubiquitination by the DNA Damage Response Is Required for Efficient DNA Replication in Unperturbed S Phase von Schmid, Jonas Andreas, Berti, Matteo, Walser, Franziska, Raso, Maria Chiara, Schmid, Fabian, Krietsch, Jana, Stoy, Henriette, Zwicky, Katharina, Ursich, Sebastian, Freire, Raimundo, Lopes, Massimo, Penengo, Lorenza

“… Chromatin ubiquitination by the ubiquitin ligase RNF168 is critical to regulate the DNA damage response (DDR). DDR deficiencies lead to cancer-prone syndromes, …”
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Mind-controlled transgene expression by a wireless-powered optogenetic designer cell implant von Folcher, Marc, Oesterle, Sabine, Zwicky, Katharina, Thekkottil, Thushara, Heymoz, Julie, Hohmann, Muriel, Christen, Matthias, Daoud El-Baba, Marie, Buchmann, Peter, Fussenegger, Martin

“… Synthetic devices for traceless remote control of gene expression may provide new treatment opportunities in future gene- and cell-based therapies. Here we …”
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