Search Results - "Zeltins, Andris"

Construction and Characterization of Virus-Like Particles: A Review by Zeltins, Andris

“…Over the last three decades, virus-like particles (VLPs) have evolved to become a widely accepted technology, especially in the field of vaccinology. In fact,…”
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Recent Advances in the Use of Plant Virus-Like Particles as Vaccines by Balke, Ina, Zeltins, Andris

“…Vaccination is one of the most effective public health interventions of the 20th century. All vaccines can be classified into different types, such as vaccines…”
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Vaccine against peanut allergy based on engineered virus-like particles displaying single major peanut allergens by Storni, Federico, Zeltins, Andris, Balke, Ina, Heath, Matthew D., Kramer, Matthias F., Skinner, Murray A., Zha, Lisha, Roesti, Elisa, Engeroff, Paul, Muri, Lukas, von Werdt, Diego, Gruber, Thomas, Cragg, Mark, Mlynarczyk, Malgorzata, Kündig, Thomas M., Vogel, Monique, Bachmann, Martin F.

“…Peanut allergy is a severe and increasingly frequent disease with high medical, psychosocial, and economic burden for affected patients and wider society…”
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Ryegrass mottle virus complete genome determination and development of infectious cDNA by combining two methods– 3′ RACE and RNA-Seq by Balke, Ina, Silamikelis, Ivars, Radovica-Spalvina, Ilze, Zeltina, Vilija, Resevica, Gunta, Fridmanis, Davids, Zeltins, Andris

“…Ryegrass mottle virus (RGMoV; genus: Sobemovirus ) is a single-stranded positive RNA virus with a 30 nm viral particle size. It exhibits T = 3 symmetry with…”
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The next generation virus‐like particle platform for the treatment of peanut allergy by Sobczak, Jan M., Krenger, Pascal S., Storni, Federico, Mohsen, Mona O., Balke, Ina, Reseviča, Gunta, Heath, Matthew D., Carreno Velazquez, Thalia L., Kramer, Matthias F., Scott, Callum J. W., Skinner, Murray A., Zeltiņš, Andris, Kündig, Thomas M., Vogel, Monique, Bachmann, Martin F.

“…Background Allergy to peanut is one of the leading causes of anaphylactic reactions among food allergic patients. Immunization against peanut allergy with a…”
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Bacterial expression systems based on Tymovirus-like particles for the presentation of vaccine antigens by Ogrina, Anete, Balke, Ina, Kalnciema, Ieva, Skrastina, Dace, Jansons, Juris, Bachmann, Martin F., Zeltins, Andris

“…Virus-like particles (VLPs) are virus-derived artificial nanostructures that resemble a native virus-stimulating immune system through highly repetitive…”
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Virus-Like Particles Are Efficient Tools for Boosting mRNA-Induced Antibodies by Vogt, Anne-Cathrine S., Jörg, Lukas, Martina, Byron, Krenger, Pascal S., Chang, Xinyue, Zeltins, Andris, Vogel, Monique, Mohsen, Mona O., Bachmann, Martin F.

“…mRNA based vaccines against COVID-19 have proven most successful at keeping SARS-CoV-2 pandemic at bay in many countries. Recently, there is an increased…”
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Vaccination using mutated receptor binding domains of SARS-CoV-2: Evidence for partial immune escape but not serotype formation by Chang, Xinyue, Liu, Xuelan, Martina, Byron, Zeltins, Andris, Augusto, Gilles, Vogel, Monique, Mohsen, Mona O., Speiser, Daniel E., Bachmann, Martin F.

“…SARS-CoV-2 has developed a number of Variants of Concern (VOC) with increased infectivity and/or reduced recognition by neutralizing antibodies specific for…”
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Incorporation of tetanus-epitope into virus-like particles achieves vaccine responses even in older recipients in models of psoriasis, Alzheimer’s and cat allergy by Zeltins, Andris, West, Jonathan, Zabel, Franziska, El Turabi, Aadil, Balke, Ina, Haas, Stefanie, Maudrich, Melanie, Storni, Federico, Engeroff, Paul, Jennings, Gary T., Kotecha, Abhay, Stuart, David I, Foerster, John, Bachmann, Martin F.

“…Monoclonal antibodies are widely used to treat non-infectious conditions but are costly. Vaccines could offer a cost-effective alternative but have been…”
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Dynamics of Magnetotactic Bacteria in a Rotating Magnetic Field by Ērglis, Kaspars, Wen, Qi, Ose, Velta, Zeltins, Andris, Sharipo, Anatolijs, Janmey, Paul A., Cēbers, Andrejs

“…The dynamics of the motile magnetotactic bacterium Magnetospirillum gryphiswaldense in a rotating magnetic field is investigated experimentally and analyzed by…”
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Neutralization of MERS coronavirus through a scalable nanoparticle vaccine by Mohsen, Mona O., Rothen, Dominik, Balke, Ina, Martina, Byron, Zeltina, Vilija, Inchakalody, Varghese, Gharailoo, Zahra, Nasrallah, Gheyath, Dermime, Said, Tars, Kaspars, Vogel, Monique, Zeltins, Andris, Bachmann, Martin F.

“…MERS-CoV continues to cause human outbreaks, so far in 27 countries worldwide following the first registered epidemic in Saudi Arabia in 2012. In this study,…”
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Comparison of Bacterial Expression Systems Based on Potato Virus Y-like Particles for Vaccine Generation by Ogrina, Anete, Skrastina, Dace, Balke, Ina, Kalnciema, Ieva, Jansons, Juris, Bachmann, Martin F., Zeltins, Andris

“…Plant-based virus-like particle (VLP) vaccines have been studied for years, demonstrating their potential as antigen-presenting platforms. In this paper, we…”
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Vaccination with nanoparticles combined with micro-adjuvants protects against cancer by Mohsen, Mona O., Heath, Matthew D., Cabral-Miranda, Gustavo, Lipp, Cyrill, Zeltins, Andris, Sande, Marcos, Stein, Jens V., Riether, Carsten, Roesti, Elisa, Zha, Lisha, Engeroff, Paul, El-Turabi, Aadil, Kundig, Thomas M., Vogel, Monique, Skinner, Murray A., Speiser, Daniel E., Knuth, Alexander, Kramer, Matthias F., Bachmann, Martin F.

“…Background Induction of strong T cell responses, in particular cytotoxic T cells, is a key for the generation of efficacious therapeutic cancer vaccines which…”
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Induction of Broadly Cross-Reactive Antibodies by Displaying Receptor Binding Domains of SARS-CoV-2 on Virus-like Particles by Chang, Xinyue, Liu, Xuelan, Mohsen, Mona O., Zeltins, Andris, Martina, Byron, Vogel, Monique, Bachmann, Martin F.

“…The impact of the COVID-19 pandemic has been reduced since the application of vaccination programs, mostly shown in the reduction of hospitalized patients…”
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A Novel Double Mosaic Virus-like Particle-Based Vaccine against SARS-CoV-2 Incorporates Both Receptor Binding Motif (RBM) and Fusion Domain by Chang, Xinyue, Zeltins, Andris, Mohsen, Mona O., Gharailoo, Zahra, Zha, Lisha, Liu, Xuelan, Walton, Senta, Vogel, Monique, Bachmann, Martin F.

“…COVID-19 has emerged, and has rapidly become a major health problem worldwide, causing millions of mortalities. Vaccination against COVID-19 is the most…”
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Identifying Key Drivers of Efficient B Cell Responses: On the Role of T Help, Antigen-Organization, and Toll-like Receptor Stimulation for Generating a Neutralizing Anti-Dengue Virus Response by Sobczak, Jan M., Barkovska, Irena, Balke, Ina, Rothen, Dominik A., Mohsen, Mona O., Skrastina, Dace, Ogrina, Anete, Martina, Byron, Jansons, Juris, Bogans, Janis, Vogel, Monique, Bachmann, Martin F., Zeltins, Andris

“…T help (Th), stimulation of toll-like receptors (pathogen-associated molecular patterns, PAMPs), and antigen organization and repetitiveness…”
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Probing novel epitopes on the Plasmodium falciparum circumsporozoite protein for vaccine development by Krenger, Pascal S., Roques, Magali, Vogt, Anne-Cathrine S., Pardini, Alessandro, Rothen, Dominik A., Balke, Ina, Schnider, Sophie T., Mohsen, Mona O., Heussler, Volker T., Zeltins, Andris, Bachmann, Martin F.

“…RTS,S and R21 are the only vaccines recommended by the WHO to protect children from Plasmodium falciparum (Pf) clinical malaria. Both vaccines target the Pf…”
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Identification and Full Genome Analysis of the First Putative Virus of Sea Buckthorn (Hippophae rhamnoides L.) by Balke, Ina, Zeltina, Vilija, Zrelovs, Nikita, Kalnciema, Ieva, Resevica, Gunta, Ludviga, Rebeka, Jansons, Juris, Moročko-Bičevska, Inga, Segliņa, Dalija, Zeltins, Andris

“…The agricultural importance of sea buckthorn (SBT; Hippophae rhamnoides L.) is rapidly increasing. Several bacterial and fungal pathogens infecting SBT have…”
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Use of plant viruses and virus-like particles for the creation of novel vaccines by Balke, Ina, Zeltins, Andris

“…In recent decades, the development of plant virology and genetic engineering techniques has resulted in the construction of plant virus-based vaccines for…”
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Crystal structure of human gamma-butyrobetaine hydroxylase by Tars, Kaspars, Rumnieks, Janis, Zeltins, Andris, Kazaks, Andris, Kotelovica, Svetlana, Leonciks, Ainars, Sharipo, Jelena, Viksna, Arturs, Kuka, Janis, Liepinsh, Edgars, Dambrova, Maija

“…► Crystal structure of gamma-butyrobetaine hydroxylase solved at 2 Å resoluttion. ► Novel dimerization interface among 2-ketoglutarate oxygenases. ► Unique…”
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