Search Results - "Zürcher, Lisa M."

Division of labor within the DNA damage tolerance system reveals non-epistatic and clinically actionable targets for precision cancer medicine by Spanjaard, Aldo, Shah, Ronak, de Groot, Daniël, Buoninfante, Olimpia Alessandra, Morris, Ben, Lieftink, Cor, Pritchard, Colin, Zürcher, Lisa M, Ormel, Shirley, Catsman, Joyce J I, de Korte-Grimmerink, Renske, Siteur, Bjørn, Proost, Natalie, Boadum, Terry, van de Ven, Marieke, Song, Ji-Ying, Kreft, Maaike, van den Berk, Paul C M, Beijersbergen, Roderick L, Jacobs, Heinz

“…Crosslink repair depends on the Fanconi anemia pathway and translesion synthesis polymerases that replicate over unhooked crosslinks. Translesion synthesis is…”
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Gemcitabine as chemotherapy of head and neck cancer in Fanconi anemia patients by van Harten, Anne M., Shah, Ronak, de Boer, D. Vicky, Buijze, Marijke, Kreft, Maaike, Song, Ji-Ying, Zürcher, Lisa M., Jacobs, Heinz, Brakenhoff, Ruud H.

“…Fanconi anemia (FA) is a rare hereditary disease resulting from an inactivating mutation in the FA/BRCA pathway, critical for the effective repair of DNA…”
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Dual role of proliferating cell nuclear antigen monoubiquitination in facilitating Fanconi anemia-mediated interstrand crosslink repair by Shah, Ronak, Aslam, Muhammad Assad, Spanjaard, Aldo, de Groot, Daniel, Zürcher, Lisa M, Altelaar, Maarten, Hoekman, Liesbeth, Pritchard, Colin E J, Pilzecker, Bas, van den Berk, Paul C M, Jacobs, Heinz

“…Abstract The Fanconi anemia (FA) repair pathway governs repair of highly genotoxic DNA interstrand crosslinks (ICLs) and relies on translesion synthesis (TLS)…”
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