Výsledky vyhľadávania - "You, Yuyi"

Amyloid-beta and tau protein beyond Alzheimer's disease Autor Abyadeh, Morteza, Gupta, Vivek, Paulo, Joao A., Mahmoudabad, Arezoo Gohari, Shadfar, Sina, Mirshahvaladi, Shahab, Gupta, Veer, Nguyen, Christine T.O., Finkelstein, David I., You, Yuyi, Haynes, Paul A., Salekdeh, Ghasem H., Graham, Stuart L., Mirzaei, Mehdi

“…Abstract The aggregation of amyloid-beta peptide and tau protein dysregulation are implicated to play key roles in Alzheimer's disease pathogenesis and are…”
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Editorial: Retinal Changes in Neurological Diseases Autor Sharma, Samridhi, You, Yuyi

“…The study shows that deposition of amyloid-β plaques leads to thickening of the retina with subsequently reduced light responses of retinal ganglion cells…”
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Retinoid X Receptor: Cellular and Biochemical Roles of Nuclear Receptor with a Focus on Neuropathological Involvement Autor Sharma, Samridhi, Shen, Ting, Chitranshi, Nitin, Gupta, Veer, Basavarajappa, Devaraj, Sarkar, Soumalya, Mirzaei, Mehdi, You, Yuyi, Krezel, Wojciech, Graham, Stuart L., Gupta, Vivek

“…Retinoid X receptors (RXRs) present a subgroup of the nuclear receptor superfamily with particularly high evolutionary conservation of ligand binding domain…”
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Effects of Internal Limiting Membrane Peel for Idiopathic Epiretinal Membrane Surgery: A Systematic Review of Randomized Controlled Trials Autor Far, Parsa Mehraban, Yeung, Shanna C., Ma, Patrick E., Hurley, Bernard, Kertes, Peter, You, Yuyi, Yan, Peng

“…The purpose of this study was to compare functional and anatomical outcomes after epiretinal membrane (ERM) peeling with internal limiting membrane (ERM/ILM)…”
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Expansion of chronic lesions is linked to disease progression in relapsing-remitting multiple sclerosis patients Autor Klistorner, Samuel, Barnett, Michael H, Yiannikas, Con, Barton, Joshua, Parratt, John, You, Yuyi, Graham, Stuart L, Klistorner, Alexander

“…Slow-burning inflammation is putatively associated with lesion expansion and leads to progressive loss of axons and disability worsening.BACKGROUNDSlow-burning…”
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BDNF Polymorphism: A Review of Its Diagnostic and Clinical Relevance in Neurodegenerative Disorders Autor Shen, Ting, You, Yuyi, Joseph, Chitra, Mirzaei, Mehdi, Klistorner, Alexander, Graham, Stuart L., Gupta, Vivek

“…Brain-derived neurotrophic factor (BDNF) has a unique role in the neuronal development, differentiation, and survival in the developing and adult nervous…”
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Latency delay of visual evoked potential is a real measurement of demyelination in a rat model of optic neuritis Autor You, Yuyi, Klistorner, Alexander, Thie, Johnson, Graham, Stuart L

“…To investigate the relationship between size of demyelinated lesion, extent of axonal loss, and degree of latency delay of visual evoked potentials (VEPs) in a…”
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Visualizing traumatic brain injury: ocular clues for diagnosis and assessment Autor Abyadeh, Morteza, Gupta, Vivek, You, Yuyi, Paulo, Joao A., Mirzaei, Mehdi

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TrkB Receptor Agonist 7,8 Dihydroxyflavone is Protective Against the Inner Retinal Deficits Induced by Experimental Glaucoma Autor Gupta, Vivek, Chitranshi, Nitin, Gupta, Veer, You, Yuyi, Rajput, Rashi, Paulo, Joao A., Mirzaei, Mehdi, van den Buuse, Maarten, Graham, Stuart L.

“…•7,8 dihydroxyflavone protects inner retina against functional and structural losses in glaucoma.•Protective effects of 7,8 DHF in glaucoma are not affected by…”
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Loss of Shp2 Rescues BDNF/TrkB Signaling and Contributes to Improved Retinal Ganglion Cell Neuroprotection Autor Chitranshi, Nitin, Dheer, Yogita, Mirzaei, Mehdi, Wu, Yunqi, Salekdeh, Ghasem H, Abbasi, Mojdeh, Gupta, Veer, Vander Wall, Roshana, You, Yuyi, Graham, Stuart L, Gupta, Vivek

“…Glaucoma is characterized by the loss of retinal ganglion cells (RGC), and accordingly the preservation of RGCs and their axons has recently attracted…”
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Glaucoma Pathogenesis and Neurotrophins: Focus on the Molecular and Genetic Basis for Therapeutic Prospects Autor Chitranshi, Nitin, Dheer, Yogita, Abbasi, Mojdeh, You, Yuyi, Graham, Stuart L, Gupta, Vivek

“…Retinal ganglion cell (RGC) degeneration is a major feature of glaucoma pathology. Neuroprotective approaches that delay or halt the progression of RGC loss…”
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Anti-inflammatory Effects of Siponimod in a Mouse Model of Excitotoxicity-Induced Retinal Injury Autor Basavarajappa, Devaraj, Gupta, Vivek, Chitranshi, Nitin, Viswanathan, Deepa, Gupta, Veer, Vander Wall, Roshana, Palanivel, Viswanthram, Mirzaei, Mehdi, You, Yuyi, Klistorner, Alexander, Graham, Stuart L.

“…Glaucoma is a leading cause of permanent blindness worldwide and is characterized by neurodegeneration linked to progressive retinal ganglion cell (RGC) death,…”
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Bexarotene Modulates Retinoid-X-Receptor Expression and Is Protective Against Neurotoxic Endoplasmic Reticulum Stress Response and Apoptotic Pathway Activation Autor Dheer, Yogita, Chitranshi, Nitin, Gupta, Veer, Abbasi, Mojdeh, Mirzaei, Mehdi, You, Yuyi, Chung, Roger, Graham, Stuart L., Gupta, Vivek

“…Retinoid X-receptors (RXRs) are members of the ligand-dependent transcription factor family of nuclear receptors that have gained recent research focus as…”
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Age-related neurodegenerative disease associated pathways identified in retinal and vitreous proteome from human glaucoma eyes Autor Mirzaei, Mehdi, Gupta, Veer B., Chick, Joel M., Greco, Todd M., Wu, Yunqi, Chitranshi, Nitin, Wall, Roshana Vander, Hone, Eugene, Deng, Liting, Dheer, Yogita, Abbasi, Mojdeh, Rezaeian, Mahdie, Braidy, Nady, You, Yuyi, Salekdeh, Ghasem Hosseini, Haynes, Paul A., Molloy, Mark P., Martins, Ralph, Cristea, Ileana M., Gygi, Steven P., Graham, Stuart L., Gupta, Vivek K.

“…Abstarct Glaucoma is a chronic disease that shares many similarities with other neurodegenerative disorders of the central nervous system. This study was…”
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Cell Cycle Deficits in Neurodegenerative Disorders: Uncovering Molecular Mechanisms to Drive Innovative Therapeutic Development Autor Joseph, Chitra, Mangani, Abubakar Siddiq, Gupta, Veer, Chitranshi, Nitin, Shen, Ting, Dheer, Yogita, KB, Devaraj, Mirzaei, Mehdi, You, Yuyi, Graham, Stuart L, Gupta, Vivek

“…Cell cycle dysregulation has been implicated in the pathogenesis of neurodegenerative disorders. Specialised function obligates neuronal cells to subsist in a…”
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Expansion of chronic MS lesions is associated with an increase of radial diffusivity in periplaque white matter Autor Klistorner, Samuel, Barnett, Michael H, Yiannikas, Con, Barton, Joshua, Parratt, John, You, Yuyi, Graham, Stuart L, Klistorner, Alexander

“…Expansion of chronic multiple sclerosis (MS) lesion is associated with slow-burning inflammation at lesion rim. However, the underlying mechanisms leading to…”
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Retinoid x receptor modulation protects against ER stress response and rescues glaucoma phenotypes in adult mice Autor Dheer, Yogita, Chitranshi, Nitin, Gupta, Veer, Sharma, Samridhi, Pushpitha, Kanishka, Abbasi, Mojdeh, Mirzaei, Mehdi, You, Yuyi, Graham, Stuart L., Gupta, Vivek

“…Retinoid X receptors (RXRs) play an important role in transcription, are involved in numerous cellular networks from cell proliferation to lipid metabolism and…”
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Evolving geographic diversity in SARS-CoV2 and in silico analysis of replicating enzyme 3CLpro targeting repurposed drug candidates Autor Chitranshi, Nitin, Gupta, Vivek K., Rajput, Rashi, Godinez, Angela, Pushpitha, Kanishka, Shen, Ting, Mirzaei, Mehdi, You, Yuyi, Basavarajappa, Devaraj, Gupta, Veer, Graham, Stuart L.

“…Background Severe acute respiratory syndrome (SARS) has been initiating pandemics since the beginning of the century. In December 2019, the world was hit again…”
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Retinal thickness and vascular parameters using optical coherence tomography in Alzheimer's disease: a meta-analysis Autor Sheriff, Samran, Shen, Ting, Abdal, Sandra, Saks, Danit, Mirzaei, Mehdi, Gupta, Veer, Chitranshi, Nitin, You, Yuyi, Schultz, Angela, Graham, Stuart, Gupta, Vivek

“…Examining the retinal tissue has the potential to provide a unique method and technique to quantify Alzheimer's disease-related changes in participants at…”
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Differentiating axonal loss and demyelination in chronic MS lesions: A novel approach using single streamline diffusivity analysis Autor Klistorner, Samuel, Barnett, Michael H., Wasserthal, Jakob, Yiannikas, Con, Barton, Joshua, Parratt, John, You, Yuyi, Graham, Stuart L., Klistorner, Alexander

“…We describe a new single-streamline based approach to analyse diffusivity within chronic MS lesions. We used the proposed method to examine diffusivity…”
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