Suchergebnisse - "Yanover, Eva"

Overlapping functions of Hdac1 and Hdac2 in cell cycle regulation and haematopoiesis von Wilting, Roel H, Yanover, Eva, Heideman, Marinus R, Jacobs, Heinz, Horner, James, van der Torre, Jaco, DePinho, Ronald A, Dannenberg, Jan-Hermen

“… Histone deacetylases (HDACs) counterbalance acetylation of lysine residues, a protein modification involved in numerous biological processes. Here, Hdac1 and …”
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Sin3a-associated Hdac1 and Hdac2 are essential for hematopoietic stem cell homeostasis and contribute differentially to hematopoiesis von Heideman, M. R., Lancini, C., Proost, N., Yanover, E., Jacobs, H., Dannenberg, J.-H.

“… Class I histone deacetylases are critical regulators of gene transcription by erasing lysine acetylation. Targeting histone deacetylases using relative …”
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Improved potency and selectivity of an oncolytic E1ACR2 and E1B19K deleted adenoviral mutant in prostate and pancreatic cancers von Oberg, Daniel, Yanover, Eva, Adam, Virginie, Sweeney, Katrina, Costas, Celina, Lemoine, Nick R, Halldén, Gunnel

“… Replication-selective oncolytic adenoviruses are a promising class of tumor-targeting agents with proven safety in hundreds of patients. However, clinical …”
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Dosage-dependent tumor suppression by histone deacetylases 1 and 2 through regulation of c-Myc collaborating genes and p53 function von Heideman, Marinus R, Wilting, Roel H, Yanover, Eva, Velds, Arno, de Jong, Johann, Kerkhoven, Ron M, Jacobs, Heinz, Wessels, Lodewyk F, Dannenberg, Jan-Hermen

“… Histone deacetylases (HDACs) are epigenetic erasers of lysine-acetyl marks. Inhibition of HDACs using small molecule inhibitors (HDACi) is a potential strategy …”
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