Výsledky vyhľadávania - "Wirkner, Kerstin"
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Evaluating selection bias in a population-based cohort study with low baseline participation: the LIFE-Adult-Study
ISSN: 1471-2288, 1471-2288Vydavateľské údaje: London BioMed Central 01.07.2019Vydané v BMC medical research methodology (01.07.2019)“…Background Participation in epidemiologic studies is steadily declining, which may result in selection bias. It is therefore an ongoing challenge to clarify…”
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Psychometric evaluation of the Generalized Anxiety Disorder Screener GAD-7, based on a large German general population sample
ISSN: 0165-0327, 1573-2517Vydavateľské údaje: Netherlands Elsevier B.V 01.03.2017Vydané v Journal of affective disorders (01.03.2017)“…The Generalized Anxiety Disorder Scales GAD-7 and GAD-2 are instruments for the assessment of anxiety. The aims of this study are to test psychometric…”
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Impact of social isolation on grey matter structure and cognitive functions: A population-based longitudinal neuroimaging study
ISSN: 2050-084X, 2050-084XVydavateľské údaje: England eLife Sciences Publications Ltd 20.06.2023Vydané v eLife (20.06.2023)“…Social isolation has been suggested to increase the risk to develop cognitive decline. However, our knowledge on causality and neurobiological underpinnings is…”
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Reference intervals of nine steroid hormones over the life-span analyzed by LC-MS/MS: Effect of age, gender, puberty, and oral contraceptives
ISSN: 0960-0760, 1879-1220, 1879-1220Vydavateľské údaje: England Elsevier Ltd 01.10.2019Vydané v The Journal of steroid biochemistry and molecular biology (01.10.2019)“…•Reference intervals of steroid hormones from 0.3 to 80 years old for LC–MS/MS.•Continuous age-dependent reference intervals of steroid hormones with…”
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Sex-Specific Differences in Circumpapillary Retinal Nerve Fiber Layer Thickness
ISSN: 1549-4713, 1549-4713Vydavateľské údaje: United States 01.03.2020Vydané v Ophthalmology (Rochester, Minn.) (01.03.2020)“…To investigate the role of sex on retinal nerve fiber layer (RNFL) thickness at 768 circumpapillary locations based on OCT findings. Population-based…”
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Genome- and transcriptome-wide association meta-analysis reveals new insights into genes affecting coronary and peripheral artery disease
ISSN: 1932-6203, 1932-6203Vydavateľské údaje: United States Public Library of Science 18.11.2025Vydané v PloS one (18.11.2025)“…A low ankle-brachial Index (ABI) is an established condition for peripheral artery disease (PAD) and cardiovascular disease risk. The search for genetic…”
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Genome-wide association analysis of pulse wave velocity traits provide new insights into the causal relationship between arterial stiffness and blood pressure
ISSN: 1932-6203, 1932-6203Vydavateľské údaje: San Francisco Public Library of Science 13.08.2020Vydané v PloS one (13.08.2020)“…Background The pathophysiology of arterial stiffness is not completely understood. Pulse wave velocity (PWV) is an established marker for arterial stiffness…”
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Characteristics of a tattooed population and a possible role of tattoos as a risk factor for chronic diseases: Results from the LIFE-Adult-Study
ISSN: 1932-6203, 1932-6203Vydavateľské údaje: United States Public Library of Science 09.09.2025Vydané v PloS one (09.09.2025)“…Tattoos and permanent make-up (PMU) gain increasing popularity among the general population. There are indications that pigments or their fragments may…”
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Higher BMI, but not obesity-related genetic polymorphisms, correlates with lower structural connectivity of the reward network in a population-based study
ISSN: 0307-0565, 1476-5497, 1476-5497Vydavateľské údaje: England Nature Publishing Group 01.03.2021Vydané v International Journal of Obesity (01.03.2021)“…Obesity is of complex origin, involving genetic and neurobehavioral factors. Genetic polymorphisms may increase the risk for developing obesity by modulating…”
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Olfactory function is associated with cognitive performance: results from the population-based LIFE-Adult-Study
ISSN: 1758-9193, 1758-9193Vydavateľské údaje: London BioMed Central 10.05.2019Vydané v Alzheimer's research & therapy (10.05.2019)“…Background Studies in older adults or those with cognitive impairment have shown associations between cognitive and olfactory performance, but there are few…”
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What Builds Resilience? Sociodemographic and Social Correlates in the Population-Based LIFE-Adult-Study
ISSN: 1660-4601, 1661-7827, 1660-4601Vydavateľské údaje: Basel MDPI AG 04.08.2022Vydané v International journal of environmental research and public health (04.08.2022)“…Resilience is closely related to mental health and well-being. Identifying risk groups with lower resilience and the variables associated with resilience…”
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Novel Anthropometry Based on 3D-Bodyscans Applied to a Large Population Based Cohort
ISSN: 1932-6203, 1932-6203Vydavateľské údaje: United States Public Library of Science 28.07.2016Vydané v PloS one (28.07.2016)“…Three-dimensional (3D) whole body scanners are increasingly used as precise measuring tools for the rapid quantification of anthropometric measures in…”
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Genetically regulated gene expression and proteins revealed discordant effects
ISSN: 1932-6203, 1932-6203Vydavateľské údaje: United States Public Library of Science 23.05.2022Vydané v PloS one (23.05.2022)“…Although gene-expression (GE) and protein levels are typically strongly genetically regulated, their correlation is known to be low. Here we investigate this…”
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Renal function and lipid metabolism are major predictors of circumpapillary retinal nerve fiber layer thickness—the LIFE-Adult Study
ISSN: 1741-7015, 1741-7015Vydavateľské údaje: London BioMed Central 07.09.2021Vydané v BMC medicine (07.09.2021)“…Background Circumpapillary retinal nerve fiber layer thickness (cpRNFLT) as assessed by spectral domain optical coherence tomography (SD-OCT) is a new…”
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Genome-wide analysis of carotid plaque burden suggests a role of IL5 in men
ISSN: 1932-6203, 1932-6203Vydavateľské údaje: United States Public Library of Science 29.05.2020Vydané v PloS one (29.05.2020)“…Carotid artery plaque is an established marker of subclinical atherosclerosis with pronounced sex-dimorphism. Here, we aimed to identify genetic variants…”
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Genome-wide association meta-analysis of human olfactory identification discovers sex-specific and sex-differential genetic variants
ISSN: 2041-1723, 2041-1723Vydavateľské údaje: London Nature Publishing Group UK 01.07.2025Vydané v Nature communications (01.07.2025)“…Smelling is a human sense, expressing strong sexual dimorphisms. We aim to improve the knowledge of the genetics of human olfactory perception by performing an…”
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Impact of medication on blood transcriptome reveals off-target regulations of beta-blockers
ISSN: 1932-6203, 1932-6203Vydavateľské údaje: United States Public Library of Science 21.04.2022Vydané v PloS one (21.04.2022)“…For many drugs, mechanisms of action with regard to desired effects and/or unwanted side effects are only incompletely understood. To investigate possible…”
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Association of serum 25-hydroxyvitamin D concentrations with sleep phenotypes in a German community sample
ISSN: 1932-6203, 1932-6203Vydavateľské údaje: United States Public Library of Science 05.07.2019Vydané v PloS one (05.07.2019)“…Sleep disorders and vitamin D deficiency are among the most common health problems. Few studies investigated the effect of vitamin D on objectively recorded…”
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Leptin, but not ghrelin, is associated with food addiction scores in a population-based subject sample
ISSN: 1664-0640, 1664-0640Vydavateľské údaje: Switzerland Frontiers Media S.A 25.07.2023Vydané v Frontiers in psychiatry (25.07.2023)“…Ghrelin and leptin are both peptide hormones and act as opposing players in the regulation of hunger, satiety and energy expenditure. Leptin reduces appetite…”
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Investigating people’s attitudes towards participating in longitudinal health research: an intersectionality-informed perspective
ISSN: 1475-9276, 1475-9276Vydavateľské údaje: London BioMed Central 31.01.2023Vydané v International journal for equity in health (31.01.2023)“…Background Increasing evidence suggests that participation proportions in longitudinal health research vary according to sex/gender, age, social class, or…”
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