Suchergebnisse - "Willis, Elinor"

Pathology in Practice von Willis, Elinor E, Niedringhaus, Kevin D, Ballard, Jennifer R, Nemeth, Nicole M

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Onchocerca sp. in an imported Zangersheide gelding causing suspensory ligament desmitis von Brown, Kara A., Johnson, Amy L., Bender, Susan J., Nolan, Thomas J., Pfisterer, Bianca, Slack, JoAnn, Willis, Elinor, Rule, Emily K.

“… A 5‐year‐old imported Zangersheide gelding was evaluated for SC swellings over both forelimbs and lameness localized to the distal metacarpus. Ultrasound …”
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BMP Signaling and the Maintenance of Primordial Germ Cell Identity in Drosophila Embryos von Deshpande, Girish, Willis, Elinor, Chatterjee, Sandip, Fernandez, Robert, Dias, Kristen, Schedl, Paul

“… The specification of primordial germ cells (PGCs) and subsequent maintenance of germ-line identity in Drosophila embryos has long been thought to occur solely …”
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Analysis of vector genome integrations in multicentric lymphoma after AAV gene therapy in a severe hemophilia A dog von Van Gorder, Lucas, Doshi, Bhavya S., Willis, Elinor, Nichols, Timothy C., Cook, Emma, Everett, John K., Merricks, Elizabeth P., Arruda, Valder R., Bushman, Frederic D., Callan, Mary Beth, Samelson-Jones, Benjamin J.

“… Adeno-associated viral (AAV) vectors have traditionally been viewed as predominantly nonintegrating, with limited concerns for oncogenesis. However, …”
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22 Humanized NOG-EXL mice exhibit improved overall survival and less severe myeloid cell activation relative to humanized NSG-SGM3 mice von Willis, Elinor, Verrelle, Jillian, Banerjee, Esha, Assenmacher, Charles-Antoine, Tarrant, James C, Skuli, Nicolas, Jacobson, Moriah L, Binder, Zev, Radaelli, Enrico

“… BackgroundEngraftment efficiency of human immune cell lineages in super immunodeficient mice varies, and numerous strains have been developed to improve …”
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5 Severely immunodeficient NOG-EXL mice allow for humanization and development of a human glioblastoma-derived tumor microenvironment von Binder, Zev, Lamrani, Lamia, Secreto, Anthony, Skuli, Nicholas, Jacobson, Moriah, Assenmacher, Charles-Antoine, Willis, Elinor, Radaelli, Enrico, O’Rourke, Donald, Alanio, Cecile, Nasrallah, Maclean

“… BackgroundCellular immunotherapy has resulted in tremendous therapeutic advances across liquid tumors. However, for solid tumors, including glioblastoma (GBM), …”
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Characterization of host immune cell infiltrate in human CAR T cell-mediated xenogeneic graft versus host disease in NSG mice von Willis, Elinor, Banerjee, Esha, Verrelle, Jillian, Cox, Arin, Assenmacher, Charles-Antoine, Radaelli, Enrico

“… Chimeric antigen receptor (CAR) T cells are revolutionary cancer therapies that are Food and Drug Administration-approved for hematologic malignancies and …”
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Zika virus protection by a single low-dose nucleoside-modified mRNA vaccination von Pardi, Norbert, Hogan, Michael J., Pelc, Rebecca S., Muramatsu, Hiromi, Andersen, Hanne, DeMaso, Christina R., Dowd, Kimberly A., Sutherland, Laura L., Scearce, Richard M., Parks, Robert, Wagner, Wendeline, Granados, Alex, Greenhouse, Jack, Walker, Michelle, Willis, Elinor, Yu, Jae-Sung, McGee, Charles E., Sempowski, Gregory D., Mui, Barbara L., Tam, Ying K., Huang, Yan-Jang, Vanlandingham, Dana, Holmes, Veronica M., Balachandran, Harikrishnan, Sahu, Sujata, Lifton, Michelle, Higgs, Stephen, Hensley, Scott E., Madden, Thomas D., Hope, Michael J., Karikó, Katalin, Santra, Sampa, Graham, Barney S., Lewis, Mark G., Pierson, Theodore C., Haynes, Barton F., Weissman, Drew

“… A single, low-dose intradermal immunization with lipid-nanoparticle-encapsulated nucleoside-modified mRNA encoding the pre-membrane and envelope glycoproteins …”
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Characterization of Zika virus binding and enhancement potential of a large panel of flavivirus murine monoclonal antibodies von Willis, Elinor, Hensley, Scott E.

“… Zika viruses (ZIKVs) are circulating in parts of the world endemic for other flavivirus infections. Some cross-reactive antibodies (Abs) elicited by prior …”
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Nucleoside-modified mRNA vaccination partially overcomes maternal antibody inhibition of de novo immune responses in mice von Willis, Elinor, Pardi, Norbert, Parkhouse, Kaela, Mui, Barbara L, Tam, Ying K, Weissman, Drew, Hensley, Scott E

“… Maternal antibodies provide short-term protection to infants against many infections. However, they can inhibit de novo antibody responses in infants elicited …”
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Techniques to study chimerism at the tissue level in humanized mice von Cox, Arin, Banerjee, Esha, Verrelle, Jillian, Willis, Elinor, Assenmacher, Charles-Antoine, Finesso, Giovanni, Tarrant, James C, Radaelli, Enrico

“… Understanding the origin, distribution, and biology of different cell populations in chimeric mice is critical for interpreting the pathological changes …”
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Preclinical evaluation of antigen-specific B-cell depletion for phospholipase A2 receptor membranous nephropathy with chimeric autoantibody receptor T cells von Altun, Burcin, Zhao, Gexin, Wang, Baomei, Mao, Xuming, Manfredo-Vieira, Silvio, Willis, Elinor, Radaelli, Enrico, Goodman, Emma E, Boesteanu, Alina C, Gill, Saar I, Patel, Darshil R, Wong, Steven, Cottman-Thomas, Ebony, Hogan, Jonathan J, Payne, Aimee S

“… Phospholipase A2 receptor (PLA2R)-associated membranous nephropathy (MN) is a leading cause of nephrotic syndrome in adults, driven by autoantibodies that …”
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Spontaneous early-onset neurodegeneration in the brainstem and spinal cord of NSG, NOG, and NXG mice von Finesso, Giovanni, Willis, Elinor, Tarrant, James Carmine, Lanza, Matthew, Sprengers, Justin, Verrelle, Jillian, Banerjee, Esha, Hermans, Els, Assenmacher, Charles-Antoine, Radaelli, Enrico

“… The spectrum of background, incidental, and experimentally induced lesions affecting NSG and NOG mice has been the subject of intense investigation. However, …”
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Diagnostic challenge in veterinary pathology: Otitis in a humanized NOG-EXL mouse von Willis, Elinor, Verrelle, Jillian, Secreto, Anthony, Cole, Stephen D, McClung, George, Weinfurtner, Kelley M, Gade, Terence P F, Radaelli, Enrico

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Humanization with CD34-positive hematopoietic stem cells in NOG-EXL mice results in improved long-term survival and less severe myeloid cell hyperactivation phenotype relative to NSG-SGM3 mice von Willis, Elinor, Verrelle, Jillian, Banerjee, Esha, Assenmacher, Charles-Antoine, Tarrant, James C, Skuli, Nicholas, Jacobson, Moriah L, O'Rouke, Donald M, Binder, Zev A, Radaelli, Enrico

“… NSG-SGM3 and NOG-EXL mice combine severe immunodeficiency with transgenic expression of human myeloid stimulatory cytokines, resulting in marked expansion of …”
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The Effect of Maternal Antibodies on Anti-viral Immunity in Infant Mice von Willis, Elinor

“… Infants are particularly vulnerable to infection and severe disease, yet we lack effective vaccines for this population. While maternal antibodies can provide …”
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Canine H3N8 influenza vaccines partially protect mice against the canine H3N2 strain currently circulating in the United States von Willis, Elinor, Parkhouse, Kaela, Krammer, Florian, Hensley, Scott E.

“… •Canine H3N8 vaccines elicit antibodies that react strongly to canine H3N2 viruses.•Abs elicited by canine H3N8 vaccines bind to the HA stalk region of canine …”
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Immune targeting and host-protective effects of the latent stage of Toxoplasma gondii von Eberhard, Julia N, Shallberg, Lindsey A, Winn, Aaron, Chandrasekaran, Sambamurthy, Giuliano, Christopher J, Merritt, Emily F, Willis, Elinor, Konradt, Christoph, Christian, David A, Aldridge, Daniel L, Bunkofske, Molly E, Jacquet, Maxime, Dzierszinski, Florence, Katifori, Eleni, Lourido, Sebastian, Koshy, Anita A, Hunter, Christopher A

“… Latency is a microbial strategy for persistence. For Toxoplasma gondii the bradyzoite stage forms long-lived cysts critical for transmission, and its presence …”
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The latent stage of Toxoplasma gondii is targeted by the immune response and host protective von Shallberg, Lindsey A, Eberhard, Julia N, Winn, Aaron, Chandrasekaran, Sambamurthy, Giuliano, Christopher J, Merritt, Emily F, Willis, Elinor, Christian, David A, Aldridge, Daniel L, Bunkofske, Molly, Jacquet, Maxime, Dzierszinski, Florence, Katifori, Eleni, Lourido, Sebastian, Koshy, Anita A, Hunter, Christopher A

“… Latency is a microbial strategy for persistence. For Toxoplasma gondii the ability of the bradyzoite stage to form long-lived cysts is critical for …”
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