Search Results - "Wilkinson, Ian B"

Uses of Arterial Stiffness in Clinical Practice by Wilkinson, Ian B, Mäki-Petäjä, Kaisa M, Mitchell, Gary F

“…As far back as the ancient Egyptians and Greeks, physicians have observed and interpreted the arterial pulse to diagnose disease. In the last 20 years,…”
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Biomarkers and clinical outcomes in COPD: a systematic review and meta-analysis by Fermont, Jilles M, Masconi, Katya L, Jensen, Magnus T, Ferrari, Renata, Di Lorenzo, Valéria A P, Marott, Jacob M, Schuetz, Philipp, Watz, Henrik, Waschki, Benjamin, Müllerova, Hana, Polkey, Michael I, Wilkinson, Ian B, Wood, Angela M

“…BackgroundConventional measures to evaluate COPD may fail to capture systemic problems, particularly musculoskeletal weakness and cardiovascular disease…”
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A longitudinal study of maternal cardiovascular function from preconception to the postpartum period by Mahendru, Amita A, Everett, Thomas R, Wilkinson, Ian B, Lees, Christoph C, McEniery, Carmel M

“…Our objective was to investigate the extent of changes in maternal cardiovascular function, lipids and renal function during normal pregnancy from…”
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Design, characterization, and first-in-human study of the vascular actions of a novel biased apelin receptor agonist by Brame, Aimee L, Maguire, Janet J, Yang, Peiran, Dyson, Alex, Torella, Rubben, Cheriyan, Joseph, Singer, Mervyn, Glen, Robert C, Wilkinson, Ian B, Davenport, Anthony P

“…[Pyr(1)]apelin-13 is an endogenous vasodilator and inotrope but is downregulated in pulmonary hypertension and heart failure, making the apelin receptor an…”
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Review of the Techniques Used for Investigating the Role Elastin and Collagen Play in Arterial Wall Mechanics by Giudici, Alessandro, Wilkinson, Ian B., Khir, Ashraf W.

“…The arterial wall is characterised by a complex microstructure that impacts the mechanical properties of the vascular tissue. The main components consist of…”
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Placental syndromes and maternal cardiovascular health by Casey, Helen, Dennehy, Natalie, Fraser, Abigail, Lees, Christoph, McEniery, Carmel M, Scott, Kayley, Wilkinson, Ian B, Delles, Christian

“…The placental syndromes gestational hypertension, preeclampsia and intrauterine growth restriction are associated with an increased cardiovascular risk to the…”
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Mechanisms of Vascular Dysfunction in COPD and Effects of a Novel Soluble Epoxide Hydrolase Inhibitor in Smokers by Yang, Lucy, Cheriyan, Joseph, Gutterman, David D, Mayer, Ruth J, Ament, Zsuzsanna, Griffin, Jules L, Lazaar, Aili L, Newby, David E, Tal-Singer, Ruth, Wilkinson, Ian B

“…Smoking and COPD are risk factors for cardiovascular disease, and the pathogenesis may involve endothelial dysfunction. We tested the hypothesis that…”
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Association between hypertensive disorders of pregnancy and later risk of cardiovascular outcomes by Oliver-Williams, Clare, Stevens, David, Payne, Rupert A., Wilkinson, Ian B., Smith, Gordon C. S., Wood, Angela

“…Background Hypertensive disorders of pregnancy are common pregnancy complications that are associated with greater cardiovascular disease risk for mothers…”
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Pharmacokinetics, pharmacodynamics and adverse event profile of GSK2256294, a novel soluble epoxide hydrolase inhibitor by Lazaar, Aili L., Yang, Lucy, Boardley, Rebecca L., Goyal, Navin S., Robertson, Jonathan, Baldwin, Sandra J., Newby, David E., Wilkinson, Ian B., Tal‐Singer, Ruth, Mayer, Ruth J., Cheriyan, Joseph

“…Aims Endothelial‐derived epoxyeicosatrienoic acids may regulate vascular tone and are metabolized by soluble epoxide hydrolase enzymes (sEH). GSK2256294 is a…”
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Effects of Oral Lycopene Supplementation on Vascular Function in Patients with Cardiovascular Disease and Healthy Volunteers: A Randomised Controlled Trial by Gajendragadkar, Parag R., Hubsch, Annette, Mäki-Petäjä, Kaisa M., Serg, Martin, Wilkinson, Ian B., Cheriyan, Joseph

“…The mechanisms by which a 'Mediterranean diet' reduces cardiovascular disease (CVD) burden remain poorly understood. Lycopene is a potent antioxidant found in…”
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The nitric oxide pathway and possible therapeutic options in pre‐eclampsia by Johal, Tamanrit, Lees, Christoph C., Everett, Thomas R., Wilkinson, Ian B.

“…Pre‐eclampsia is a serious multisystem disorder with diverse clinical manifestations. Although not causal, endothelial dysfunction and reduced nitric oxide…”
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Physical Activity, Sedentary Behavior, and Long‐Term Changes in Aortic Stiffness: The Whitehall II Study by Ahmadi‐Abhari, Sara, Sabia, Severine, Shipley, Martin J., Kivimäki, Mika, Singh‐Manoux, Archana, Tabak, Adam, McEniery, Carmel, Wilkinson, Ian B., Brunner, Eric J.

“…Background Physical activity is associated with reduced cardiovascular disease risk, mainly through effects on atherosclerosis. Aortic stiffness may be an…”
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The Role of the Autonomic Nervous System in the Regulation of Aortic Stiffness by Mäki-Petäjä, Kaisa M, Barrett, Sharon M L, Evans, Sarah V, Cheriyan, Joseph, McEniery, Carmel M, Wilkinson, Ian B

“…The autonomic nervous system is important in regulating blood pressure, but whether it regulates aortic stiffness is more contentious. We conducted 3 studies…”
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Diurnal pattern of salivary cortisol and progression of aortic stiffness: Longitudinal study by Ikeda, Ai, Steptoe, Andrew, Shipley, Martin, Abell, Jessica, Kumari, Meena, Tanigawa, Takeshi, Iso, Hiroyasu, Wilkinson, Ian B., McEniery, Carmel M., Singh-Manoux, Archana, Kivimaki, Mika, Brunner, Eric J.

“…The positive direct relation between stress and the development of cardiovascular disease has increasingly been recognized. However, the link between…”
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Comparison of the effects of antihypertensive agents on central blood pressure and arterial stiffness in isolated systolic hypertension by Mackenzie, Isla S, McEniery, Carmel M, Dhakam, Zahid, Brown, Morris J, Cockcroft, John R, Wilkinson, Ian B

“…Isolated systolic hypertension is an important risk factor for cardiovascular disease and results primarily from elastic artery stiffening. Although various…”
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Exenatide and glucagon co-infusion increases myocardial glucose uptake and improves markers of diastolic dysfunction in adults with type 2 diabetes by Goodman, James, Schain, Martin, Di Stefano, Giovanni, Lupson, Victoria, Horn, Tracy, Hill, Marion, Manavaki, Roie, Fryer, Timothy D., Bumanlag-Amis, Elaine, Jalaludeen, Navazh, Jermutus, Lutz, Johansson, Edvin, Heurling, Kerstin, Haraldsson, Henrik, Evans, Mark, Cheriyan, Joseph, Johansson, Lars, Ambery, Philip, Wilkinson, Ian B.

“…Type 2 diabetes (T2D) significantly increases the risk of heart failure, a major cause of hospitalisation and increased morbidity and mortality. Dual and…”
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The relationship of age with regional aortic stiffness and diameter by Hickson, Stacey S, Butlin, Mark, Graves, Martin, Taviani, Valentina, Avolio, Alberto P, McEniery, Carmel M, Wilkinson, Ian B

“…The purpose of this study was to determine the impact of age on regional aortic pulse wave velocity (aPWV). aPWV is an independent predictor of cardiovascular…”
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Short physical performance battery as a practical tool to assess mortality risk in chronic obstructive pulmonary disease by Fermont, Jilles M, Mohan, Divya, Fisk, Marie, Bolton, Charlotte E, Macnee, William, Cockcroft, John R, McEniery, Carmel, Fuld, Jonathan, Cheriyan, Joseph, Tal-Singer, Ruth, Müllerova, Hana, Wood, Angela M, Wilkinson, Ian B, Polkey, Michael I

“…Abstract Rationale chronic obstructive pulmonary disease (COPD) is a leading cause of mortality and common in older adults. The BODE Index is the most…”
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Validity and repeatability of the Vicorder apparatus : a comparison with the SphygmoCor device by Hickson, Stacey S, Butlin, Mark, Broad, Jeremy, Avolio, Alberto P, Wilkinson, Ian B, McEniery, Carmel M

“…Aortic stiffness, an independent predictor of cardiovascular risk and all-cause mortality, can be estimated non-invasively by measuring carotid to femoral…”
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AGE, HYPERTENSION AND ARTERIAL FUNCTION by McEniery, Carmel M, Wilkinson, Ian B, Avolio, Albert P

“…SUMMARY 1 Ageing exerts a marked effect on the cardiovascular system and, in particular, the large arteries. Using a variety of techniques to assess arterial…”
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