Search Results - "Weston, A.H."

Effects of isoleucine, lysine, valine, and a group of nonessential amino acids on mammary amino acid metabolism in lactating dairy cows by Weston, A.H., Fernandes, T., de Oliveira, M., Gaskin, S., Pilonero, T., Hanigan, M.D.

“…Intracellular AA regulate milk protein synthesis within the mammary gland by modifying mammary plasma flow (MPF) and AA transporter activity. Amino acid…”
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Comparison of the effects of BRL 34915 and verapamil on electrical and mechanical activity in rat portal vein by Hamilton, T C, Weir, S W, Weston, A H

“…The effects of the novel anti-hypertensive agent BRL 34915, (+/-) 6-cyano-3,4-dihydro-2,2-dimethyl-trans-4-(2-oxo-1-pyrrolidyl)-2H-b enzo[b]pyran-3-ol, have…”
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Induction of a glibenclamide-sensitive K-current by modification of a delayed rectifier channel in rat portal vein in insulinoma cells by Edwards, G, Weston, A H

“…In insulinoma cells (RINm5F), the glibenclamide-sensitive K-current (IK(ATP)) which developed spontaneously or after exposure to levcromakalim or to…”
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Effects of rubidium on responses to potassium channel openers in rat isolated aorta by Greenwood, I A, Weston, A H

“…1. In a physiological salt solution (PSS) in which potassium (K) was replaced by rubidium (Rb), segments of rat aorta precontracted with 20 mM RbCl were fully…”
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Influence of the vascular endothelium on agonist-induced contractions and relaxations in rat aorta by Bullock, G R, Taylor, S G, Weston, A H

“…The influence of the vascular endothelium on agonist-induced contractions and relaxations has been measured using intact segments of rat aorta. Contiguous…”
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Effect of apamin on responses to BRL 34915, nicorandil and other relaxants in the guinea-pig taenia caeci by Weir, S W, Weston, A H

“…BRL 34915 (4-64 X 10(-7) M), isoprenaline (0.5-32 X 10(-8) M) and nicorandil (4-64 X 10(-6) M) produced a slowly-developing relaxation of spontaneous tone of…”
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Characteristics of cromakalim-induced relaxations in the smooth muscle cells of guinea-pig mesenteric artery and vein by Nakao, K, Okabe, K, Kitamura, K, Kuriyama, H, Weston, A H

“…1. The effects of cromakalim (BRL 34915) on the smooth muscle cells of guinea-pig mesenteric artery and vein were investigated with microelectrode and tension…”
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Analysis of the depressant effect of the endothelium on contractions of rabbit isolated basilar artery to 5-hydroxytryptamine by Trezise, D J, Drew, G M, Weston, A H

“…1. The effects of endothelium removal and of a number of pharmacological agents known to modify endothelial cell function on the contractile response of rabbit…”
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The relaxant action of BRL 34915 in rat uterus by Hollingsworth, M, Amédée, T, Edwards, D, Mironneau, J, Savineau, J P, Small, R C, Weston, A H

“…1 BRL 34915 (0.04-1.3 microM) caused concentration-dependent inhibition of spontaneous phasic spasms of the isolated uterus of the term pregnant rat and this…”
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The potassium channel opening action of pinacidil; studies using biochemical, ion flux and microelectrode techniques by Southerton, J S, Weston, A H, Bray, K M, Newgreen, D T, Taylor, S G

“…In rat aorta and rat portal vein, (-)- and (+)-pinacidil each produced a concentration-dependent inhibition of tension development. Although the (-) isomer was…”
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Effects of calcium entry blockers on tension development and calcium influx in rat uterus by Granger, S E, Hollingsworth, M, Weston, A H

“…Spontaneous and potassium chloride (KCl)-induced tension development of strips of whole uterus from the day-22 pregnant rat was reduced when the tissues were…”
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A comparison of several calcium antagonists on uterine, vascular and cardiac muscles from the rat by Granger, S E, Hollingsworth, M, Weston, A H

“…An assessment was made of the potencies of nifedipine, gallopamil, diltiazem, cinnarizine and salbutamol as inhibitors of tension development by the uterus and…”
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The effects of BRL 34915 and nicorandil on electrical and mechanical activity and on 86Rb efflux in rat blood vessels by Weir, S W, Weston, A H

“…The effects of the antihypertensive agent BRL 34915 on a variety of responses of the aorta and portal vein of the rat have been compared with those of…”
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Ion channel modulation by NS 1619, the putative BKCa channel opener, in vascular smooth muscle by Edwards, G, Niederste-Hollenberg, A, Schneider, J, Noack, T, Weston, A H

“…1. The effects of NS 1619, the putative BKCa channel opener, were investigated on rat intact portal veins and on single smooth muscle cells enzymatically…”
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Cromakalim, nicorandil and pinacidil: novel drugs which open potassium channels in smooth muscle by Hamilton, T C, Weston, A H

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Comparison of the effects of several potassium-channel openers on rat bladder and rat portal vein in vitro by Edwards, G, Henshaw, M, Miller, M, Weston, A H

“…1. The ability of several K-channel openers to inhibit KCl-induced contractions of rat bladder detrusor and spontaneous mechanical activity in rat portal vein…”
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Levcromakalim may induce a voltage-independent K-current in rat portal veins by modifying the gating properties of the delayed rectifier by Edwards, G, Ibbotson, T, Weston, A H

“…1. Smooth muscle cells of the rat portal vein were dispersed by enzymatic treatment and recordings of whole-cell currents under calcium-free conditions were…”
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Investigation of the effects of 5-nitro-2-(3-phenylpropylamino)-benzoic acid (NPPB) on membrane currents in rat portal vein by Kirkup, A J, Edwards, G, Weston, A H

“…1. The effects of 5-nitro-2-(3-phenylpropylamino)-benzoic acid (NPPB) were investigated on evoked and spontaneous currents in freshly-isolated cells from the…”
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Endothelium-dependent effects of acetylcholine in rat aorta: a comparison with sodium nitroprusside and cromakalim by Taylor, S G, Southerton, J S, Weston, A H, Baker, J R

“…1. The mechanisms involved in the mechano-inhibitory effects of acetylcholine (ACh) have been compared with those of sodium nitroprusside (SNP) and cromakalim…”
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Potassium channel openers and vascular smooth muscle relaxation by Edwards, G, Weston, A H

“…Potassium channel openers comprise a diverse group of chemical agents which open plasma-lemmal K-channels. They show selectivity for smooth muscle, although…”
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