Suchergebnisse - "Weismann, Dirk"

Effect of therapeutic drug monitoring-based dose optimization of piperacillin/tazobactam on sepsis-related organ dysfunction in patients with sepsis: a randomized controlled trial von Hagel, Stefan, Bach, Friedhelm, Brenner, Thorsten, Bracht, Hendrik, Brinkmann, Alexander, Annecke, Thorsten, Hohn, Andreas, Weigand, Markus, Michels, Guido, Kluge, Stefan, Nierhaus, Axel, Jarczak, Dominik, König, Christina, Weismann, Dirk, Frey, Otto, Witzke, Dominic, Müller, Carsten, Bauer, Michael, Kiehntopf, Michael, Neugebauer, Sophie, Lehmann, Thomas, Roberts, Jason A., Pletz, Mathias W.

“… Purpose Insufficient antimicrobial exposure is associated with worse outcomes in sepsis. We evaluated whether therapeutic drug monitoring (TDM)-guided …”
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Modelling variations of emergency attendances using data on community mobility, climate and air pollution von Weismann, Dirk, Möckel, Martin, Paeth, Heiko, Slagman, Anna

“… Air pollution is associated with morbidity and mortality worldwide. We investigated the impact of improved air quality during the economic lockdown during the …”
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Combination Chemotherapy in Advanced Adrenocortical Carcinoma von Fassnacht, Martin, Terzolo, Massimo, Allolio, Bruno, Baudin, Eric, Haak, Harm, Berruti, Alfredo, Welin, Staffan, Schade-Brittinger, Carmen, Lacroix, André, Jarzab, Barbara, Sorbye, Halfdan, Torpy, David J, Stepan, Vinzenz, Schteingart, David E, Arlt, Wiebke, Kroiss, Matthias, Leboulleux, Sophie, Sperone, Paola, Sundin, Anders, Hermsen, Ilse, Hahner, Stefanie, Willenberg, Holger S, Tabarin, Antoine, Quinkler, Marcus, de la Fouchardière, Christelle, Schlumberger, Martin, Mantero, Franco, Weismann, Dirk, Beuschlein, Felix, Gelderblom, Hans, Wilmink, Hanneke, Sender, Monica, Edgerly, Maureen, Kenn, Werner, Fojo, Tito, Müller, Hans-Helge, Skogseid, Britt

“… In this large international study of patients with adrenal cancer, a rare, treatment-refractory disease, mitotane plus a combination of etoposide, cisplatin, …”
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Pro- and Anti-Inflammatory Responses in Severe COVID-19-Induced Acute Respiratory Distress Syndrome—An Observational Pilot Study von Notz, Quirin, Schmalzing, Marc, Wedekink, Florian, Schlesinger, Tobias, Gernert, Michael, Herrmann, Johannes, Sorger, Lena, Weismann, Dirk, Schmid, Benedikt, Sitter, Magdalena, Schlegel, Nicolas, Kranke, Peter, Wischhusen, Jörg, Meybohm, Patrick, Lotz, Christopher

“… The severity of Coronavirus Disease 2019 (COVID-19) is largely determined by the immune response. First studies indicate altered lymphocyte counts and …”
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Clinical performance evaluation of SARS-CoV-2 rapid antigen testing in point of care usage in comparison to RT-qPCR von Wagenhäuser, Isabell, Knies, Kerstin, Rauschenberger, Vera, Eisenmann, Michael, McDonogh, Miriam, Petri, Nils, Andres, Oliver, Flemming, Sven, Gawlik, Micha, Papsdorf, Michael, Taurines, Regina, Böhm, Hartmut, Forster, Johannes, Weismann, Dirk, Weißbrich, Benedikt, Dölken, Lars, Liese, Johannes, Kurzai, Oliver, Vogel, Ulrich, Krone, Manuel

“… Background: Antigen rapid diagnostic tests (RDT) for SARS-CoV-2 are fast, broadly available, and inexpensive. Despite this, reliable clinical performance data …”
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Severe neurological complications in critically ill COVID-19 patients von Notz, Quirin, Lotz, Christopher, Herrmann, Johannes, Vogt, Marius, Schlesinger, Tobias, Kredel, Markus, Muellges, Wolfgang, Weismann, Dirk, Westermaier, Thomas, Meybohm, Patrick, Kranke, Peter

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COVID-19 and the kidney: A retrospective analysis of 37 critically ill patients using machine learning von Herzog, Anna Laura, von Jouanne-Diedrich, Holger K., Wanner, Christoph, Weismann, Dirk, Schlesinger, Tobias, Meybohm, Patrick, Stumpner, Jan

“… There is evidence that SARS-CoV2 has a particular affinity for kidney tissue and is often associated with kidney failure. We assessed whether proteinuria can …”
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Complementary and incremental mortality risk prediction by cortisol and aldosterone in chronic heart failure von Güder, Gülmisal, Bauersachs, Johann, Frantz, Stefan, Weismann, Dirk, Allolio, Bruno, Ertl, Georg, Angermann, Christiane E, Störk, Stefan

“… In patients with systolic heart failure, high levels of circulating aldosterone are associated with an adverse prognosis, and mineralocorticoid receptor …”
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New targets and therapeutic approaches for endocrine malignancies von Fassnacht, Martin, Kreissl, Michael C., Weismann, Dirk, Allolio, Bruno

“… In endocrine malignancies (thyroid carcinoma, parathyroid carcinoma, adrenocortical carcinoma, malignant pheochromocytoma) surgery is currently the treatment …”
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SirT1 knockdown in liver decreases basal hepatic glucose production and increases hepatic insulin responsiveness in diabetic rats von Erion, Derek M, Yonemitsu, Shin, Nie, Yongzhan, Nagai, Yoshio, Gillum, Matthew P, Hsiao, Jennifer J, Iwasaki, Takanori, Stark, Romana, Weismann, Dirk, Yu, Xing Xian, Murray, Susan F, Bhanot, Sanjay, Monia, Brett P, Horvath, Tamas L, Gao, Qian, Samuel, Varman T, Shulman, Gerald I

“… Hepatic gluconeogenesis is a major contributing factor to hyperglycemia in the fasting and postprandial states in type 2 diabetes mellitus (T2DM). Because …”
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Association of preclinical blood glucose with hospitalization rate and in‐hospital mortality: A single‐center retrospective cohort study von Kloock, Simon, Skudelny, Danilo, Kranke, Peter, Güder, Gülmisal, Weismann, Dirk, Fassnacht, Martin, Ziegler, Christian G., Dischinger, Ulrich

“… Critical illness is often accompanied by elevated blood glucose, which generally correlates with increased morbidity and mortality. Prehospital blood glucose …”
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Symptomatische Hyperkalzämie und hyperkalzämische Krise von Weismann, Dirk

“… Zusammenfassung Biochemisch wird die Hyperkalzämie häufig in mild (< 3 mmol/L), moderat (3–5 mmol/L) oder schwer (> 3,5 mmol/L) eingeteilt. Eine milde …”
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Correction to: Effect of therapeutic drug monitoring-based dose optimization of piperacillin/tazobactam on sepsis-related organ dysfunction in patients with sepsis: a randomized controlled trial von Hagel, Stefan, Bach, Friedhelm, Brenner, Thorsten, Bracht, Hendrik, Brinkmann, Alexander, Annecke, Thorsten, Hohn, Andreas, Weigand, Markus Alexander, Michels, Guido, Kluge, Stefan, Nierhaus, Axel, Jarczak, Dominik, König, Christina, Weismann, Dirk, Frey, Otto, Witzke, Dominic, Müller, Carsten, Bauer, Michael, Kiehntopf, Michael, Neugebauer, Sophie, Lehmann, Thomas, Roberts, Jason A., Pletz, Mathias W.

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Plasma Metabolome Profiling for the Diagnosis of Catecholamine Producing Tumors von März, Juliane, Kurlbaum, Max, Roche-Lancaster, Oisin, Deutschbein, Timo, Peitzsch, Mirko, Prehn, Cornelia, Weismann, Dirk, Robledo, Mercedes, Adamski, Jerzy, Fassnacht, Martin, Kunz, Meik, Kroiss, Matthias

“… Pheochromocytomas and paragangliomas (PPGL) cause catecholamine excess leading to a characteristic clinical phenotype. Intra-individual changes at metabolome …”
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Management of adrenocortical carcinoma von Allolio, Bruno, Hahner, Stefanie, Weismann, Dirk, Fassnacht, Martin

“… Summary Adrenocortical carcinoma (ACC) is a rare neoplasm with poor prognosis. Patients present with signs of steroid hormone excess (e.g. Cushing's syndrome, …”
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Motion Detectors as Additional Monitoring Devices in the Intensive Care Unit—A Proof-of-Concept Study von Güder, Gülmisal, von Rein, Eva, Flohr, Thomas, Weismann, Dirk, Schmitt, Dominik, Störk, Stefan, Frantz, Stefan, Kratzer, Vincent, Kendi, Christian

“… Background: Monitoring the vital signs of delirious patients in an intensive care unit (ICU) is challenging, as they might (un-)intentionally remove devices …”
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Prevention of hepatic steatosis and hepatic insulin resistance by knockdown of cAMP response element-binding protein von Erion, Derek M, Ignatova, Irena D, Yonemitsu, Shin, Nagai, Yoshio, Chatterjee, Paula, Weismann, Dirk, Hsiao, Jennifer J, Zhang, Dongyan, Iwasaki, Takanori, Stark, Romana, Flannery, Clare, Kahn, Mario, Carmean, Christopher M, Yu, Xing Xian, Murray, Susan F, Bhanot, Sanjay, Monia, Brett P, Cline, Gary W, Samuel, Varman T, Shulman, Gerald I

“… In patients with poorly controlled type 2 diabetes mellitus (T2DM), hepatic insulin resistance and increased gluconeogenesis contribute to fasting and …”
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Adrenal Crisis von Weismann, Dirk

“… According to long-term studies, patients with adrenal insufficiency (AI) exhibit a reduced quality of life and increased mortality. In addition to …”
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COVID-19 Induced Acute Respiratory Distress Syndrome—A Multicenter Observational Study von Herrmann, Johannes, Adam, Elisabeth Hannah, Notz, Quirin, Helmer, Philipp, Sonntagbauer, Michael, Ungemach-Papenberg, Peter, Sanns, Andreas, Zausig, York, Steinfeldt, Thorsten, Torje, Iuliu, Schmid, Benedikt, Schlesinger, Tobias, Rolfes, Caroline, Reyher, Christian, Kredel, Markus, Stumpner, Jan, Brack, Alexander, Wurmb, Thomas, Gill-Schuster, Daniel, Kranke, Peter, Weismann, Dirk, Klinker, Hartwig, Heuschmann, Peter, Rücker, Viktoria, Frantz, Stefan, Ertl, Georg, Muellenbach, Ralf Michael, Mutlak, Haitham, Meybohm, Patrick, Zacharowski, Kai, Lotz, Christopher

“… Background: Proportions of patients dying from the coronavirus disease-19 (COVID-19) vary between different countries. We report the characteristics; clinical …”
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Single Nucleotide Polymorphism Microarray Analysis in Cortisol-Secreting Adrenocortical Adenomas Identifies New Candidate Genes and Pathways von Ronchi, Cristina L., Leich, Ellen, Sbiera, Silviu, Weismann, Dirk, Rosenwald, Andreas, Allolio, Bruno, Fassnacht, Martin

“… The genetic mechanisms underlying adrenocortical tumor development are still largely unknown. We used high-resolution single nucleotide polymorphism …”
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