Suchergebnisse - "Watkins, Timothy A"

Considerations for viral co-infection studies in human populations von Chin, Taylor, Foxman, Ellen F., Watkins, Timothy A., Lipsitch, Marc

“… When respiratory viruses co-circulate in a population, individuals may be infected with multiple pathogens and experience possible virus-virus interactions, …”
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Application of B cell immortalization for the isolation of antibodies and B cell clones from vaccine and infection settings von Boswell, Kristin L., Watkins, Timothy A., Cale, Evan M., Samsel, Jakob, Andrews, Sarah F., Ambrozak, David R., Driscoll, Jefferson I., Messina, Michael A., Narpala, Sandeep, Hopp, Christine S., Cagigi, Alberto, Casazza, Joseph P., Yamamoto, Takuya, Zhou, Tongqing, Schief, William R., Crompton, Peter D., Ledgerwood, Julie E., Connors, Mark, Gama, Lucio, Kwong, Peter D., McDermott, Adrian, Mascola, John R., Koup, Richard A.

“… The isolation and characterization of neutralizing antibodies from infection and vaccine settings informs future vaccine design, and methodologies that …”
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Nasal host response-based screening for undiagnosed respiratory viruses: a pathogen surveillance and detection study von Cheemarla, Nagarjuna R, Hanron, Amelia, Fauver, Joseph R, Bishai, Jason, Watkins, Timothy A, Brito, Anderson F, Zhao, Dejian, Alpert, Tara, Vogels, Chantal B F, Ko, Albert I, Schulz, Wade L, Landry, Marie L, Grubaugh, Nathan D, van Dijk, David, Foxman, Ellen F

“… Symptomatic patients who test negative for common viruses are an important possible source of unrecognised or emerging pathogens, but metagenomic sequencing of …”
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Dynamic innate immune response determines susceptibility to SARS-CoV-2 infection and early replication kinetics von Cheemarla, Nagarjuna R, Watkins, Timothy A, Mihaylova, Valia T, Wang, Bao, Zhao, Dejian, Wang, Guilin, Landry, Marie L, Foxman, Ellen F

“… Initial replication of SARS-CoV-2 in the upper respiratory tract is required to establish infection, and the replication level correlates with the likelihood …”
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Viral Interference During Influenza A-SARS-CoV-2 Coinfection of the Human Airway Epithelium and Reversal by Oseltamivir von Cheemarla, Nagarjuna R, Watkins, Timothy A, Mihaylova, Valia T, Foxman, Ellen F

“… To gain insight into interactions among respiratory viruses, we modeled influenza A virus (IAV)-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …”
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Detection of Live Attenuated Measles Virus in the Respiratory Tract Following Subcutaneous Measles-Mumps-Rubella Vaccination von Watkins, Timothy A, Brockhurst, Jacqueline K, Germain, Gregory, Griffin, Diane E, Foxman, Ellen F

“… The live attenuated measles vaccine is extremely effective in preventing measles and induces mucosal immunity in the respiratory tract; however, the mechanism …”
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High burden of viruses and bacterial pathobionts drives heightened nasal innate immunity in children von Watkins, Timothy A, Green, Alex B, Amat, Julien A R, Cheemarla, Nagarjuna R, Hänsel, Katrin, Lozano, Richard, Dudgeon, Sarah N, Germain, Gregory, Landry, Marie L, Schulz, Wade L, Foxman, Ellen F

“… Studies during the COVID-19 pandemic showed that children had heightened nasal innate immune responses compared with adults. To evaluate the role of nasal …”
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Nasal biomarker testing to rule out viral respiratory infection and triage samples: a test performance study von Amat, Julien A.R., Dudgeon, Sarah N., Cheemarla, Nagarjuna R., Watkins, Timothy A., Green, Alex B., Young, H. Patrick, Peaper, David R., Landry, Marie L., Schulz, Wade L., Foxman, Ellen F.

“… The COVID-19 pandemic revealed an urgent need for practical screening tests to rule out respiratory virus infection, both for managing outbreaks and for …”
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Airway choices in maxillofacial trauma von Watkins, Timothy A., Opie, Neil J., Norman, Aidan

“… Successful management of the patient's airway is central to the safe practice of anaesthesia. Whilst anaesthetists are faced with an ever increasing range of …”
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Reply to McMahon et. al von Watkins, Timothy A, Brockhurst, Jacqueline K, Germain, Gregory, Foxman, Ellen F

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Counterintuitive effect of antiviral therapy on influenza A-SARS-CoV-2 coinfection due to viral interference von Cheemarla, Nagarjuna R, Mihaylova, Valia T, Watkins, Timothy A, Foxman, Ellen F

“… The resurgence of influenza and continued circulation of SARS-CoV-2 raise the question of how these viruses interact in a co-exposed host. Here we studied …”
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Magnitude and timing of the antiviral response determine SARS-CoV-2 replication early in infection von Cheemarla, Nagarjuna R, Watkins, Timothy A, Mihaylova, Valia T, Wang, Bao, Zhao, Dejian, Wang, Guilin, Landry, Marie L, Foxman, Ellen F

“… The interferon response is a potent antiviral defense mechanism, but its effectiveness depends on its timing relative to viral replication. Here, we report …”
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Detection of live attenuated measles virus in the respiratory tract following subcutaneous MMR Vaccination von Watkins, Timothy A, Brockhurst, Jacqueline K, Germain, Gregory, Griffin, Diane E, Foxman, Ellen F

“… The live attenuated measles vaccine is extremely effective in preventing measles and induces mucosal immunity in the respiratory tract, however the mechanism …”
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Multivariate analysis of glycogenes reveals coordinated regulation of immunoglobulin glycosylation in an immortalized human B cell system von Wiggins, Christine D, Sangés Ametllé, Marina, Wu, Claire, Boswell, Kristin L, Watkins, Timothy A, Koup, Richard A, Lauffenburger, Douglas A

“… While neutralizing ability has traditionally been considered the most important antibody function, appreciation has grown for Fc-mediated 'extra-neutralizing' …”
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LETTERS: Home Edition von Robert M. Horne, Jendi Reiter, Edward A. Watkins, Timothy Still, Rob Medley, Troudy Hough

“… Editor: [Tom Ehrich]'s column (Faith & Values, Feb. 3) on the pitfalls of President [Bush]'s faith-based initiative raised some interesting concerns, but I …”
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