Výsledky vyhľadávania - "Vlaar, Alexander P."

Transfusion-related acute lung injury: a clinical review Autor Vlaar, Alexander PJ, Juffermans, Nicole P

“…Three decades ago, transfusion-related acute lung injury (TRALI) was considered a rare complication of transfusion medicine. Nowadays, the US Food and Drug…”
Získať plný text

The pathophysiology of sepsis and precision-medicine-based immunotherapy Autor Giamarellos-Bourboulis, Evangelos J., Aschenbrenner, Anna C., Bauer, Michael, Bock, Christoph, Calandra, Thierry, Gat-Viks, Irit, Kyriazopoulou, Evdoxia, Lupse, Mihaela, Monneret, Guillaume, Pickkers, Peter, Schultze, Joachim L., van der Poll, Tom, van de Veerdonk, Frank L., Vlaar, Alexander P. J., Weis, Sebastian, Wiersinga, W. Joost, Netea, Mihai G.

“…Sepsis remains a major cause of morbidity and mortality in both low- and high-income countries. Antibiotic therapy and supportive care have significantly…”
Získať plný text

Blood transfusion: the search for the sweet spot Autor Vlaar, Alexander P. J.

Získať plný text

A guide to immunotherapy for COVID-19 Autor van de Veerdonk, Frank L., Giamarellos-Bourboulis, Evangelos, Pickkers, Peter, Derde, Lennie, Leavis, Helen, van Crevel, Reinout, Engel, Job J., Wiersinga, W. Joost, Vlaar, Alexander P. J., Shankar-Hari, Manu, van der Poll, Tom, Bonten, Marc, Angus, Derek C., van der Meer, Jos W. M., Netea, Mihai G.

“…Immune dysregulation is an important component of the pathophysiology of COVID-19. A large body of literature has reported the effect of immune-based therapies…”
Získať plný text

Transfusion strategies in bleeding critically ill adults: a clinical practice guideline from the European Society of Intensive Care Medicine Autor Vlaar, Alexander P. J., Dionne, Joanna C., de Bruin, Sanne, Wijnberge, Marije, Raasveld, S. Jorinde, van Baarle, Frank E. H. P., Antonelli, Massimo, Aubron, Cecile, Duranteau, Jacques, Juffermans, Nicole P., Meier, Jens, Murphy, Gavin J., Abbasciano, Riccardo, Müller, Marcella C. A., Lance, Marcus, Nielsen, Nathan D., Schöchl, Herbert, Hunt, Beverley J., Cecconi, Maurizio, Oczkowski, Simon

“…Purpose To develop evidence-based clinical practice recommendations regarding transfusion practices and transfusion in bleeding critically ill adults. Methods…”
Získať plný text

Diaphragm Pathology in Critically Ill Patients With COVID-19 and Postmortem Findings From 3 Medical Centers Autor Shi, Zhonghua, de Vries, Heder J, Vlaar, Alexander P J, van der Hoeven, Johannes, Boon, Reinier A, Heunks, Leo M A, Ottenheijm, Coen A C

Zistit podrobnosti o prístupe

ICU capacity management during the COVID-19 pandemic using a process simulation Autor Alban, Andres, Chick, Stephen E., Dongelmans, Dave A., Vlaar, Alexander P. J., Sent, Danielle

Získať plný text

Impact of BMI on outcomes in respiratory ECMO: an ELSO registry study Autor Peetermans, Marijke, Guler, Ipek, Meersseman, Philippe, Wilmer, Alexander, Wauters, Joost, Meyns, Bart, Vlaar, Alexander P. J., Combes, Alain, Hermans, Greet

“…Purpose The impact of body mass index (BMI) on outcomes in respiratory failure necessitating extracorporeal membrane oxygenation (ECMO) has been poorly…”
Získať plný text

Viral presence and immunopathology in patients with lethal COVID-19: a prospective autopsy cohort study Autor Schurink, Bernadette, Roos, Eva, Radonic, Teodora, Barbe, Ellis, Bouman, Catherine S C, de Boer, Hans H, de Bree, Godelieve J, Bulle, Esther B, Aronica, Eleonora M, Florquin, Sandrine, Fronczek, Judith, Heunks, Leo M A, de Jong, Menno D, Guo, Lihui, du Long, Romy, Lutter, Rene, Molenaar, Pam C G, Neefjes-Borst, E Andra, Niessen, Hans W M, van Noesel, Carel J M, Roelofs, Joris J T H, Snijder, Eric J, Soer, Eline C, Verheij, Joanne, Vlaar, Alexander P J, Vos, Wim, van der Wel, Nicole N, van der Wal, Allard C, van der Valk, Paul, Bugiani, Marianna

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) targets multiple organs and causes severe coagulopathy. Histopathological organ changes might not…”
Získať plný text

Cumulative fluid balance predicts mortality and increases time on mechanical ventilation in ARDS patients: An observational cohort study Autor van Mourik, Niels, Metske, Hennie A., Hofstra, Jorrit J., Binnekade, Jan M., Geerts, Bart F., Schultz, Marcus J., Vlaar, Alexander P. J.

“…Acute respiratory distress syndrome (ARDS) is characterized by acute, diffuse, inflammatory lung injury leading to increased pulmonary vascular permeability,…”
Získať plný text

Uncovering heterogeneity in sepsis: a comparative analysis of subphenotypes Autor van Amstel, Rombout B. E., Kennedy, Jason N., Scicluna, Brendon P., Bos, Lieuwe D. J., Peters-Sengers, Hessel, Butler, Joe M., Cano-Gamez, Eddie, Knight, Julian C., Vlaar, Alexander P. J., Cremer, Olaf L., Angus, Derek C., van der Poll, Tom, Seymour, Christopher W., van Vught, Lonneke A.

“…Purpose The heterogeneity in sepsis is held responsible, in part, for the lack of precision treatment. Many attempts to identify subtypes of sepsis patients…”
Získať plný text

Heterogeneity in a meta-analysis: randomized controlled trials versus observational studies. Author’s reply Autor Schuurmans, Jaap, Veelo, Denise P., Vlaar, Alexander P. J., Schenk, Jimmy

Získať plný text

Contemporary management of major haemorrhage in critical care Autor Maier, Cheryl L., Brohi, Karim, Curry, Nicola, Juffermans, Nicole P., Mora Miquel, Lidia, Neal, Matthew D., Shaz, Beth H., Vlaar, Alexander P. J., Helms, Julie

“…Haemorrhagic shock is frequent in critical care settings and responsible for a high mortality rate due to multiple organ dysfunction and coagulopathy. The…”
Získať plný text

Transfusion practice in the non-bleeding critically ill: an international online survey—the TRACE survey Autor de Bruin, Sanne, Scheeren, Thomas W. L., Bakker, Jan, van Bruggen, Robin, Vlaar, Alexander P. J.

“…Background Over the last decade, multiple large randomized controlled trials have studied alternative transfusion strategies in critically ill patients,…”
Získať plný text

Pre‐operative reference ranges for ROTEM® sigma in patients undergoing cardiac surgery: a secondary analysis of two prospective trial cohorts Autor Haeren, Maite M. T., Brouwers, Meike, Schenk, Jimmy, Breel, Jennifer S., Noteboom, Sijm H., Kho, Eline, Eberl, Susanne, Veelo, Denise P., Vlaar, Alexander P. J., Müller, Marcella C. A., Hermanns, Henning

“…Summary Introduction Rotational thromboelastometry (ROTEM®) is used widely in cardiac surgery. Reference ranges are derived from healthy volunteers but may not…”
Získať plný text

Pitfalls and paradoxes: blood transfusion in 5 public ICU databases Autor Reuland, Merijn C., Raasveld, Senta Jorinde, Dongelmans, Dave A., Elbers, Paul W.G., Müller, Marcella C. A., Vlaar, Alexander P. J.

Získať plný text

Hypotension during intensive care stay and mortality and morbidity: a systematic review and meta-analysis Autor Schuurmans, Jaap, van Rossem, Benthe T. B., Rellum, Santino R., Tol, Johan T. M., Kurucz, Vincent C., van Mourik, Niels, van der Ven, Ward H., Veelo, Denise P., Schenk, Jimmy, Vlaar, Alexander P. J.

“…Purpose The aim of this study is to provide a summary of the existing literature on the association between hypotension during intensive care unit (ICU) stay…”
Získať plný text

Assessing the documentation of publicly available medical image and signal datasets and their impact on bias using the BEAMRAD tool Autor Galanty, Maria, Luitse, Dieuwertje, Noteboom, Sijm H., Croon, Philip, Vlaar, Alexander P., Poell, Thomas, Sanchez, Clara I., Blanke, Tobias, Išgum, Ivana

“…Medical datasets are vital for advancing Artificial Intelligence (AI) in healthcare. Yet biases in these datasets on which deep-learning models are trained can…”
Získať plný text

A consensus redefinition of transfusion‐related acute lung injury Autor Vlaar, Alexander P.J., Toy, Pearl, Fung, Mark, Looney, Mark R., Juffermans, Nicole P., Bux, Juergen, Bolton‐Maggs, Paula, Peters, Anna L., Silliman, Christopher C., Kor, Daryl J., Kleinman, Steve

“…BACKGROUND Transfusion‐related acute lung injury (TRALI) is a serious complication of blood transfusion and is among the leading causes of transfusion‐related…”
Získať plný text

Prediction of emergency department presentations for acute coronary syndrome using a machine learning approach Autor Kurucz, Vincent C., Schenk, Jimmy, Veelo, Denise P., Geerts, Bart F., Vlaar, Alexander P. J., Van Der Ster, Björn J. P.

“…The relationship between weather and acute coronary syndrome (ACS) incidence has been the subject of considerable research, with varying conclusions…”
Získať plný text