Výsledky vyhledávání - "Virus Internalization"

Diarrhea During COVID-19 Infection: Pathogenesis, Epidemiology, Prevention, and Management Autor D'Amico, Ferdinando, Baumgart, Daniel C, Danese, Silvio, Peyrin-Biroulet, Laurent

“…The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2/COVID-19) pandemic is a worldwide emergency. An increasing number of diarrhea cases is…”
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Gene expression and in situ protein profiling of candidate SARS-CoV-2 receptors in human airway epithelial cells and lung tissue Autor Aguiar, Jennifer A, Tremblay, Benjamin J-M, Mansfield, Michael J, Woody, Owen, Lobb, Briallen, Banerjee, Arinjay, Chandiramohan, Abiram, Tiessen, Nicholas, Cao, Quynh, Dvorkin-Gheva, Anna, Revill, Spencer, Miller, Matthew S, Carlsten, Christopher, Organ, Louise, Joseph, Chitra, John, Alison, Hanson, Paul, Austin, Richard C, McManus, Bruce M, Jenkins, Gisli, Mossman, Karen, Ask, Kjetil, Doxey, Andrew C, Hirota, Jeremy A

“…To determine the expression and localisation of candidate SARS-CoV-2 receptors in the respiratory mucosa, we analysed gene expression datasets from airway epithelial cells of 515 healthy subjects…”
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Methylation Pathways and SARS-CoV-2 Lung Infiltration and Cell Membrane-Virus Fusion Are Both Subject to Epigenetics Autor Pruimboom, Leo

“…The recent pandemic SARS-CoV-2 outbreak affects all kinds of individuals worldwide. The health, social, and economic impacts of the pandemic are dramatic, and…”
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Worse progression of COVID‐19 in men: Is testosterone a key factor? Autor Giagulli, Vito A., Guastamacchia, Edoardo, Magrone, Thea, Jirillo, Emilio, Lisco, Giuseppe, De Pergola, Giovanni, Triggiani, Vincenzo

“…Background The novel severe acute respiratory syndrome coronavirus (SARS‐CoV‐2) disease 2019 (COVID‐19) seems to have a worse clinical course among infected…”
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Angiotensin-converting enzyme 2 (ACE2) receptor and SARS-CoV-2: Potential therapeutic targeting Autor Sharifkashani, Sourena, Bafrani, Melika Arab, Khaboushan, Alireza Soltani, Pirzadeh, Marzieh, Kheirandish, Ali, Yavarpour_Bali, Hanie, Hessami, Amirhossein, Saghazadeh, Amene, Rezaei, Nima

“… In conclusion, blocking or manipulating the SARS-CoV2-ACE2 binding interface perhaps offers the best tactic against the virus that should be treated as a fundamental subject…”
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Inhibition of PEDV viral entry upon blocking N-glycan elaboration Autor Zhao, Yong, Tang, Tao, Zhao, Wenchang, Fu, Weiguang, Li, Tao

“…Porcine Epidemic Diarrhea Virus (PEDV) poses a significant threat to the global swine industry, demanding a thorough understanding of its cellular invasion…”
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Direct visualization of avian influenza H5N1 hemagglutinin precursor and its conformational change by high-speed atomic force microscopy Autor Lim, Kee Siang, Mohamed, Mahmoud Shaaban, Wang, Hanbo, Hartono, Hazawa, Masaharu, Kobayashi, Akiko, Voon, Dominic Chih-Cheng, Kodera, Noriyuki, Ando, Toshio, Wong, Richard W.

“…Hemagglutinin (HA) of influenza A is one of the key virulence factors that mediates the release of viral components in host cells. HA is initially synthesized…”
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Targeted therapy strategies against SARS‐CoV‐2 cell entry mechanisms: A systematic review of in vitro and in vivo studies Autor Seyedpour, Simin, Khodaei, Behzad, Loghman, Amir H., Seyedpour, Nasrin, Kisomi, Misagh F., Balibegloo, Maryam, Nezamabadi, Sasan S., Gholami, Bahareh, Saghazadeh, Amene, Rezaei, Nima

“… Pathways of the viral entry into cells are interesting subjects for targeted therapy of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2…”
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Human herpesvirus-6 entry into the central nervous system through the olfactory pathway Autor Harberts, Erin, Yao, Karen, Wohler, Jillian E, Maric, Dragan, Ohayon, Joan, Henkin, Robert, Jacobson, Steven

“…Viruses have been implicated in the development of neurodegenerative diseases, such as Alzheimer's, Parkinson's, and multiple sclerosis. Human herpesvirus-6…”
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Ebola virus entry requires the host-programmed recognition of an intracellular receptor Autor Miller, Emily Happy, Obernosterer, Gregor, Raaben, Matthijs, Herbert, Andrew S, Deffieu, Maika S, Krishnan, Anuja, Ndungo, Esther, Sandesara, Rohini G, Carette, Jan E, Kuehne, Ana I, Ruthel, Gordon, Pfeffer, Suzanne R, Dye, John M, Whelan, Sean P, Brummelkamp, Thijn R, Chandran, Kartik

“…Ebola and Marburg filoviruses cause deadly outbreaks of haemorrhagic fever. Despite considerable efforts, no essential cellular receptors for filovirus entry…”
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COVID-19 and the pituitary Autor Frara, Stefano, Allora, Agnese, Castellino, Laura, di Filippo, Luigi, Loli, Paola, Giustina, Andrea

“… Moreover, higher mortality and poorer outcomes have been widely described in COVID-19 patients with obesity, diabetes and vertebral fractures, which are all highly prevalent in subjects with pituitary dysfunctions…”
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Impairment of endocytosis-related factors FNBP1L, ARHGAP24, and ATP6V1B1 increases HIV-1 entry into dendritic cells Autor Janevska, Marija, Witkowski, Wojciech, Vermeire, Jolien, Borowicz, Marek, Naessens, Evelien, Vanderstraeten, Hanne, Nauwynck, Hans, Favoreel, Herman, Verhasselt, Bruno

“…Understanding how HIV-1 interacts with dendritic cells (DCs) is pivotal in deciphering early viral transmission and immune evasion but is subject to a long-standing controversy in HIV virology…”
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Estimation of the initial viral growth rate and basic reproductive number during acute HIV-1 infection Autor Ribeiro, Ruy M, Qin, Li, Chavez, Leslie L, Li, Dongfeng, Self, Steven G, Perelson, Alan S

“… We studied the viral dynamics of very early HIV-1 infection in 47 subjects identified through plasma donation screening…”
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Conserved residues of the immunosuppressive domain of MLV are essential for regulating the fusion-critical SU-TM disulfide bond Autor Hogan, Victoria A, Harmon, Julia, Cid-Rosas, Miguel, Hall, Laura R, Johnson, Welkin E

“…The Env protein of murine leukemia virus (MLV) is the prototype of a large clade of retroviral fusogens, collectively known as gamma-type Envs. Gamma-type Envs…”
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The influence of ABO blood groups on COVID-19 susceptibility and severity: A molecular hypothesis based on carbohydrate-carbohydrate interactions Autor Silva-Filho, José Caetano, Melo, Cynthia Germoglio Farias de, Oliveira, Janaína Lima de

“…The world is experiencing one of the most difficult moments in history with the COVID-19 pandemic, a disease caused by SARS-CoV-2, a new type of coronavirus…”
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BK polyomavirus genotypes represent distinct serotypes with distinct entry tropism Autor Pastrana, Diana V, Ray, Upasana, Magaldi, Thomas G, Schowalter, Rachel M, Çuburu, Nicolas, Buck, Christopher B

“… We developed reporter pseudoviruses based on seven divergent BKV isolates and performed neutralization assays on sera from healthy human subjects…”
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Quantification of entry phenotypes of macrophage-tropic HIV-1 across a wide range of CD4 densities Autor Joseph, Sarah B, Arrildt, Kathryn T, Swanstrom, Adrienne E, Schnell, Gretja, Lee, Benhur, Hoxie, James A, Swanstrom, Ronald

“…Defining a macrophage-tropic phenotype for HIV-1 to assess a role in pathogenesis is complicated by the fact that HIV-1 isolates vary continuously in their…”
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Establishment of a Panel of Human Cell Lines to Identify Cellular Receptors Used by Enteroviruses to Infect Cells Autor Sosnovtseva, Anastasiia O., Le, Thi Hoa, Karpov, Dmitry S., Vorobyev, Pavel O., Gumennaya, Yana D., Alekseeva, Olga N., Chumakov, Peter M., Lipatova, Anastasia V.

“…Non-pathogenic natural and recombinant strains of human Enteroviruses are the subject of ongoing study with some strains having been approved for use as anticancer agents…”
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Cholesterol 25-hydroxylase acts as a host restriction factor on pseudorabies virus replication Autor Wang, Jiang, Zeng, Lei, Zhang, Li, Guo, Zhen-Zhen, Lu, Shao-Fang, Ming, Sheng-Li, Li, Guo-Li, Wan, Bo, Tian, Ke-Gong, Yang, Guo-Yu, Chu, Bei-Bei

“… We further identified that the anti-PRV role of CH25H and 25HC was subject to their inhibitory effect on PRV attachment and entry. Collectively, these findings demonstrate that CH25H is an intrinsic host restriction factor in PRV infection of porcine alveolar macrophages…”
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Spike substitutions E484D, P812R and Q954H mediate ACE2-independent entry of SARS-CoV-2 across different cell lines Autor Vizgirda, Greta, Underwood, Alexander P., Fahnøe, Ulrik, Weis, Nina, Ramirez, Santseharay, Bukh, Jens

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes coronavirus disease 2019 (COVID-19), has evolved into variants with multiple spike…”
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