Výsledky vyhľadávania - "Vincristine"

Vincristine Sulfate Liposomes Injection (VSLI, Marqibo®): Results From a Phase I Study in Children, Adolescents, and Young Adults With Refractory Solid Tumors or Leukemias Autor Shah, Nirali N., Merchant, Melinda S., Cole, Diane E., Jayaprakash, Nalini, Bernstein, Donna, Delbrook, Cindy, Richards, Kelly, Widemann, Brigitte C., Wayne, Alan S.

“…Background Vincristine sulfate liposome injection (VSLI; Marqibo®) is an encapsulated preparation of standard vincristine in sphingomyelin/cholesterol liposomes…”
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Patterns and severity of vincristine-induced peripheral neuropathy in children with acute lymphoblastic leukemia Autor Lavoie Smith, Ellen M., Li, Lang, Chiang, ChienWei, Thomas, Karin, Hutchinson, Raymond J., Wells, Elizabeth M., Ho, Richard H., Skiles, Jodi, Chakraborty, Arindom, Bridges, Celia M., Renbarger, Jamie

“…Vincristine, a critical component of combination chemotherapy treatment for pediatric acute lymphoblastic leukemia…”
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2535. Physiological-based pharmacokinetic analysis of drug–drug interactions between isavuconazole and vincristine in pediatric subjects Autor Choules, Mary P, Otsuka, Yukio, Kovanda, Laura, Bonate, Peter, Sinnar, Shamim, Desai, Amit

“… Pediatric patients being treated for leukemia with vincristine frequently experience secondary fungal infections, requiring treatment. Isavuconazole (ISAV…”
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Phase II study of vincristine, actinomycin-D, cyclophosphamide and irinotecan for patients with newly diagnosed low-risk subset B rhabdomyosarcoma: A study protocol Autor Miyachi, Mitsuru, Tsuchiya, Kunihiko, Hosono, Ako, Ogawa, Atsushi, Koh, Katsuyoshi, Kikuta, Atsushi, Hara, Junichi, Teramukai, Satoshi, Hosoi, Hajime

“…Approximately 80% to 90% of patients with low-risk rhabdomyosarcoma can be cured. However, cured patients often face long-term complications associated with…”
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Persistent chemoneuropathy in patients receiving the plant alkaloids paclitaxel and vincristine Autor Boyette-Davis, Jessica A., Cata, Juan P., Driver, Larry C., Novy, Diane M., Bruel, Brian M., Mooring, Deidre L., Wendelschafer-Crabb, Gwen, Kennedy, William R., Dougherty, Patrick M.

“… This study was designed to quantify the longevity of and contributions to neuropathy following treatment with the plant alkaloids paclitaxel and vincristine…”
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CYP3A5 genotype and its impact on vincristine pharmacokinetics and development of neuropathy in Kenyan children with cancer Autor Skiles, Jodi L., Chiang, ChienWei, Li, Claire H., Martin, Steve, Smith, Ellen L., Olbara, Gilbert, Jones, David R., Vik, Terry A., Mostert, Saskia, Abbink, Floor, Kaspers, Gertjan J., Li, Lang, Njuguna, Festus, Sajdyk, Tammy J., Renbarger, Jamie L.

“…Background Vincristine (VCR) is a critical part of treatment in pediatric malignancies and is associated with dose…”
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The effect of oral curcumin on vincristine-induced neuropathy in pediatric acute lymphoblastic leukemia: A double-blind randomized controlled clinical trial Autor Eghbali, Aziz, Adibifar, Mahsa, Ghasemi, Ali, Afzal, Roghayeh Rahimi, Moradi, Katayoun, Eghbali, Aygin, Faress, Foroozan, Ghaffari, Kazem

“…Background Peripheral neuropathy is a major adverse effect of Vincristine (VCR) in pediatric acute lymphoblastic leukemia (ALL) patients…”
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Pharmacokinetic Behavior of Vincristine and Safety Following Intravenous Administration of Vincristine Sulfate Liposome Injection in Chinese Patients With Malignant Lymphoma Autor Yang, Fen, Jiang, Min, Lu, Ming, Hu, Pei, Wang, Hongyun, Jiang, Ji

“…This phase Ia study was designed to assess the pharmacokinetic (PK) characters of free vincristine…”
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Vincristine-associated Neuropathy With Antifungal Usage: A Kaiser Northern California Experience Autor Nikanjam, Mina, Sun, Aida, Albers, Mark, Mangalindin, Kristine, Song, Eyun, Vempaty, Hyma, Sam, Danny, Capparelli, Edmund V

“…). In total, 130 subjects received at least one dose of vincristine for ALL or Hodgkin lymphoma (median age 9, 88% ALL, 58% male, 47% Caucasian…”
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Peripheral neuropathy in non-Hodgkin's lymphoma patients receiving vincristine with and without aprepitant/fosaprepitant Autor Edwards, Jessi K, Bossaer, John B, Lewis, Paul O, Sant, Ashley

“…Peripheral neuropathy is a common treatment-related adverse effect associated with vincristine…”
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Validation of an UPLC-MS-MS Method for Quantitative Analysis of Vincristine in Human Urine After Intravenous Administration of Vincristine Sulfate Liposome Injection Autor Yang, Fen, Wang, Hongyun, Hu, Pei, Jiang, Ji

“…Vincristine sulfate liposome injection (VSLI) is a liposomal formulation of vincristine (VCR…”
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Determination of free and total vincristine in human plasma after intravenous administration of vincristine sulfate liposome injection using ultra-high performance liquid chromatography tandem mass spectrometry Autor Yang, Fen, Wang, Hongyun, Liu, Ming, Hu, Pei, Jiang, Ji

“… ► The method was applied to the PK studies of liposomal VCR in subjects with lymphoma. Vincristine sulfate liposome is a liposomal formulation of vincristine sulfate…”
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A phase 1 trial of venetoclax in combination with liposomal vincristine in patients with relapsed or refractory B‐cell or T‐cell acute lymphoblastic leukemia: Results from the ECOG‐ACRIN EA9152 protocol Autor Palmisiano, Neil D., Lee, Ju‐Whei, Claxton, David F., Paietta, Elisabeth M., Alkhateeb, Hassan, Park, Jae, Podoltsev, Nikolai A., Atallah, Ehab L., Schaar, Dale G., Dinner, Shira N., Webster, Jonathan A., Luger, Selina M., Litzow, Mark R.

“…) remains a therapeutic challenge. Preclinical data in both B‐ and T‐ALL suggests synergy of venetoclax (VEN) with vincristine (VCR…”
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A cohort study of vincristine-induced peripheral neuropathy in children Autor Li, Chuang, Jin, Jiao, Huang, Jing, Yang, Xiao-Yan, Li, Yan, Yan, Yong-Yan, Yang, Can

“…To study the characteristics of vincristine-induced peripheral neuropathy (VIPN) in children with acute lymphoblastic leukemia (ALL…”
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Treatment of primary mediastinal B-cell lymphoma with rituximab, cyclophosphamide, doxorubicin, vincristine and prednisone is associated with a high rate of primary refractory disease Autor Soumerai, Jacob D., Hellmann, Matthew D., Feng, Yang, Sohani, Aliyah R., Toomey, Christiana E., Barnes, Jeffrey A., Takvorian, Ronald W., Neuberg, Donna, Hochberg, Ephraim P., Abramson, Jeremy S.

“…Abstract The optimal therapy for primary mediastinal B-cell lymphoma is a subject of ongoing debate, with no accepted standard of care…”
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Prognosis and complete remission rate of diffuse large B‐cell lymphoma patients in standard R‐CHOP with reduction of vincristine: A retrospective study Autor Riasi, Fatemeh, Ataei Azimi, Sajjad, Allahyari, Abolghasem, Moeini Nodeh, Mohammad, Shakeri, Mohammad T., Kamandi, Mostafa

“…Background and Aims The effect of stopping or reducing the dose of vincristine in diffuse large B‐cell lymphoma (DLBCL…”
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Switching to Bortezomib may Improve Recovery From Severe Vincristine Neuropathy in Pediatric Acute Lymphoblastic Leukemia Autor Joshi, Jaitri, Tanner, Lynn, Gilchrist, Laura, Bostrom, Bruce

“… (ALL) from vincristine to bortezomib. A total of 20 patients with ALL were switched from vincristine to bortezomib (1.3 mg/m/dose…”
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Altered Regional Brain Glucose Metabolism in Diffuse Large B-Cell Lymphoma Patients Treated With Cyclophosphamide, Epirubicin, Vincristine, and Prednisone: An Fluorodeoxyglucose Positron Emission Tomography Study of 205 Cases Autor Hu, Yuxiao, Zhang, Qin, Cui, Can, Zhang, Yun

“…) patients treated with cyclophosphamide, epirubicin, vincristine, and prednisone and controls sing positron emission tomography with 18F-labeled fluoro-2-deoxyglucose integrated with computed tomography (18F-FDG PET/CT) scanning. Methods…”
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Safe and effective dosing of basal-bolus insulin in patients receiving high-dose steroids for hyper-cyclophosphamide, doxorubicin, vincristine, and dexamethasone chemotherapy Autor Brady, Veronica, Thosani, Sonali, Zhou, Shouhou, Bassett, Roland, Busaidy, Naifa Lamki, Lavis, Victor

“…Hyperglycemia occurs in cancer patients receiving high-dose steroids with cyclophosphamide, doxorubicin, vincristine, and dexamethasone (hyper-CVAD) protocol…”
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Pharmacokinetics and Safety of Marqibo (Vincristine Sulfate Liposomes Injection) in Cancer Patients With Impaired Liver Function Autor Bedikian, Agop Y., Silverman, Jeffrey A., Papadopoulos, Nicholas E., Kim, Kevin B., Hagey, Anne E., Vardeleon, Anna, Hwu, Wen-Jen, Homsi, Jade, Davies, Michael, Hwu, Patrick

“…Marqibo (vincristine sulfate liposome injection, VSLI) is a novel liposomal formulation of vincristine sulfate (VCR…”
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