Suchergebnisse - "Vendrell, Marc"

Activatable Fluorophores for Imaging Immune Cell Function von Mendive-Tapia, Lorena, Vendrell, Marc

“… Optical imaging has become an essential tool to study biomolecular processes in live systems with unprecedented spatial resolution. New fluorescent …”
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Combinatorial strategies in fluorescent probe development von Vendrell, Marc, Zhai, Duanting, Er, Jun Cheng, Chang, Young-Tae

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Surface-enhanced Raman scattering in cancer detection and imaging von Vendrell, Marc, Maiti, Kaustabh Kumar, Dhaliwal, Kevin, Chang, Young-Tae

“… ► Assays to quantify cancer biomarkers with high sensitivity and low sample volumes. ► Imaging of cancer cells, tissues, and small animals with multiplexed …”
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Modern Synthetic Avenues for the Preparation of Functional Fluorophores von de Moliner, Fabio, Kielland, Nicola, Lavilla, Rodolfo, Vendrell, Marc

“… Biomedical research relies on the fast and accurate profiling of specific biomolecules and cells in a non‐invasive manner. Functional fluorophores are powerful …”
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Chemodivergent manganese-catalyzed C–H activation: modular synthesis of fluorogenic probes von Kaplaneris, Nikolaos, Son, Jongwoo, Mendive-Tapia, Lorena, Kopp, Adelina, Barth, Nicole D., Maksso, Isaac, Vendrell, Marc, Ackermann, Lutz

“… Bioorthogonal late-stage diversification of amino acids and peptides bears enormous potential for drug discovery and molecular imaging. Despite major …”
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Quinone-based fluorophores for imaging biological processes von Dias, Gleiston G, King, Aaron, de Moliner, Fabio, Vendrell, Marc, da Silva Júnior, Eufrânio N

“… Quinones are privileged chemical structures playing crucial roles as redox and alkylating agents in a wide range of processes in cells. The broad functional …”
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Loss of microglial MCT4 leads to defective synaptic pruning and anxiety-like behavior in mice von Monsorno, Katia, Ginggen, Kyllian, Ivanov, Andranik, Buckinx, An, Lalive, Arnaud L., Tchenio, Anna, Benson, Sam, Vendrell, Marc, D’Alessandro, Angelo, Beule, Dieter, Pellerin, Luc, Mameli, Manuel, Paolicelli, Rosa Chiara

“… Microglia, the innate immune cells of the central nervous system, actively participate in brain development by supporting neuronal maturation and refining …”
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Are model organisms representative for climate change research? Testing thermal tolerance in wild and laboratory zebrafish populations von Morgan, Rachael, Sundin, Josefin, Finnøen, Mette H, Dresler, Gunnar, Vendrell, Marc Martínez, Dey, Arpita, Sarkar, Kripan, Jutfelt, Fredrik

“… Model organisms can be useful for studying climate change impacts, but it is unclear whether domestication to laboratory conditions has altered their thermal …”
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Rational Design of Phe‐BODIPY Amino Acids as Fluorogenic Building Blocks for Peptide‐Based Detection of Urinary Tract Candida Infections von Mendive‐Tapia, Lorena, Mendive‐Tapia, David, Zhao, Can, Gordon, Doireann, Benson, Sam, Bromley, Michael J., Wang, Wei, Wu, Jun, Kopp, Adelina, Ackermann, Lutz, Vendrell, Marc

“… Fungal infections caused by Candida species are among the most prevalent in hospitalized patients. However, current methods for the detection of Candida fungal …”
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Spacer-free BODIPY fluorogens in antimicrobial peptides for direct imaging of fungal infection in human tissue von Mendive-Tapia, Lorena, Zhao, Can, Akram, Ahsan R., Preciado, Sara, Albericio, Fernando, Lee, Martin, Serrels, Alan, Kielland, Nicola, Read, Nick D, Lavilla, Rodolfo, Vendrell, Marc

“… Fluorescent antimicrobial peptides are promising structures for in situ , real-time imaging of fungal infection. Here we report a fluorogenic probe to image …”
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Photoactivatable metabolic warheads enable precise and safe ablation of target cells in vivo von Benson, Sam, de Moliner, Fabio, Fernandez, Antonio, Kuru, Erkin, Asiimwe, Nicholas L., Lee, Jun-Seok, Hamilton, Lloyd, Sieger, Dirk, Bravo, Isabel R., Elliot, Abigail M., Feng, Yi, Vendrell, Marc

“… Photoactivatable molecules enable ablation of malignant cells under the control of light, yet current agents can be ineffective at early stages of disease when …”
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A fluorogenic cyclic peptide for imaging and quantification of drug-induced apoptosis von Barth, Nicole D., Subiros-Funosas, Ramon, Mendive-Tapia, Lorena, Duffin, Rodger, Shields, Mario A., Cartwright, Jennifer A., Henriques, Sónia Troeira, Sot, Jesus, Goñi, Felix M., Lavilla, Rodolfo, Marwick, John A., Vermeren, Sonja, Rossi, Adriano G., Egeblad, Mikala, Dransfield, Ian, Vendrell, Marc

“… Programmed cell death or apoptosis is a central biological process that is dysregulated in many diseases, including inflammatory conditions and cancer. The …”
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Tuning singlet oxygen generation with caged organic photosensitizers von Nestoros, Eleni, de Moliner, Fabio, Nadal-Bufi, Ferran, Seah, Deborah, Ortega-Liebana, M. Carmen, Cheng, Zhiming, Benson, Sam, Adam, Catherine, Maierhofer, Larissa, Kozoriz, Kostiantyn, Lee, Jun-Seok, Unciti-Broceta, Asier, Vendrell, Marc

“… Controlling the succession of chemical processes with high specificity in complex systems is advantageous for widespread applications, from biomedical research …”
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A fluorogenic probe for granzyme B enables in-biopsy evaluation and screening of response to anticancer immunotherapies von Scott, Jamie I., Mendive-Tapia, Lorena, Gordon, Doireann, Barth, Nicole D., Thompson, Emily J., Cheng, Zhiming, Taggart, David, Kitamura, Takanori, Bravo-Blas, Alberto, Roberts, Edward W., Juarez-Jimenez, Jordi, Michel, Julien, Piet, Berber, de Vries, I. Jolanda, Verdoes, Martijn, Dawson, John, Carragher, Neil O., Connor, Richard A. O’, Akram, Ahsan R., Frame, Margaret, Serrels, Alan, Vendrell, Marc

“… Immunotherapy promotes the attack of cancer cells by the immune system; however, it is difficult to detect early responses before changes in tumor size occur …”
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Acid‐Resistant BODIPY Amino Acids for Peptide‐Based Fluorescence Imaging of GPR54 Receptors in Pancreatic Islets von Mendive‐Tapia, Lorena, Miret‐Casals, Laia, Barth, Nicole D., Wang, Jinling, Bray, Anne, Beltramo, Massimiliano, Robert, Vincent, Ampe, Christophe, Hodson, David J., Madder, Annemieke, Vendrell, Marc

“… The G protein‐coupled kisspeptin receptor (GPR54 or KISS1R) is an important mediator in reproduction, metabolism and cancer biology; however, there are limited …”
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The “Phagocytic Synapse” and Clearance of Apoptotic Cells von Barth, Nicole D., Marwick, John A., Vendrell, Marc, Rossi, Adriano G., Dransfield, Ian

“… Apoptosis and subsequent phagocytic clearance of apoptotic cells is important for embryonic development, maintenance of tissues that require regular cellular …”
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Multicomponent Reactions for de Novo Synthesis of BODIPY Probes: In Vivo Imaging of Phagocytic Macrophages von Vazquez-Romero, Ana, Kielland, Nicola, Arevalo, Maria J., Preciado, Sara, Mellanby, Richard J., Feng, Yi, Lavilla, Rodolfo, Vendrell, Marc

“… Multicomponent reactions are excellent tools to generate complex structures with broad chemical diversity and fluorescent properties. Herein we describe the …”
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Fluorogenic Trp(redBODIPY) cyclopeptide targeting keratin 1 for imaging of aggressive carcinomas von Subiros-Funosas, Ramon, Ho, Vivian Cheuk Lam, Barth, Nicole D, Mendive-Tapia, Lorena, Pappalardo, Morena, Barril, Xavier, Ma, Ruoyu, Zhang, Cheng-Bin, Qian, Bin-Zhi, Sintes, Miquel, Ghashghaei, Ouldouz, Lavilla, Rodolfo, Vendrell, Marc

“… Keratin 1 (KRT1) is overexpressed in squamous carcinomas and associated with aggressive pathologies in breast cancer. Herein we report the design and …”
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Preparation of a Trp-BODIPY fluorogenic amino acid to label peptides for enhanced live-cell fluorescence imaging von Mendive-Tapia, Lorena, Subiros-Funosas, Ramon, Zhao, Can, Albericio, Fernando, Read, Nick D, Lavilla, Rodolfo, Vendrell, Marc

“… Fluorescent peptides with excellent target specificity are useful imaging probes. This protocol describes the synthesis of a tryptophan-based fluorogenic amino …”
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Synthesis of a BODIPY Library and Its Application to the Development of Live Cell Glucagon Imaging Probe von Lee, Jun-Seok, Kang, Nam-young, Kim, Yun Kyung, Samanta, Animesh, Feng, Suihan, Kim, Hyeong Kyu, Vendrell, Marc, Park, Jung Hwan, Chang, Young-Tae

“… The first BODIPY library (BD) was synthesized, and a highly selective glucagon sensor, Glucagon Yellow (BD-105), was discovered by fluorescence image-based …”
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