Suchergebnisse - "Vaughan, Timothy"

IcyTree: rapid browser-based visualization for phylogenetic trees and networks von Vaughan, Timothy G

“… IcyTree is an easy-to-use application which can be used to visualize a wide variety of phylogenetic trees and networks. While numerous phylogenetic tree …”
Volltext

ReMASTER: improved phylodynamic simulation for BEAST 2.7 von Vaughan, Timothy G

“… Summary Phylodynamic models link phylogenetic trees to biologically-relevant parameters such as speciation and extinction rates (macroevolution), effective …”
Volltext

Bayesian Phylodynamic Inference of Multitype Population Trajectories Using Genomic Data von Vaughan, Timothy G, Stadler, Tanja

“… Phylodynamic methods provide a coherent framework for the inference of population parameters directly from genetic data. They are an important tool for …”
Volltext

Psychosocial Health Interventions by Social Robots: Systematic Review of Randomized Controlled Trials von Robinson, Nicole Lee, Cottier, Timothy Vaughan, Kavanagh, David John

“… Social robots that can communicate and interact with people offer exciting opportunities for improved health care access and outcomes. However, evidence from …”
Volltext

A Multitype Birth–Death Model for Bayesian Inference of Lineage-Specific Birth and Death Rates von Barido-Sottani, Joëlle, Vaughan, Timothy G, Stadler, Tanja

“… Abstract Heterogeneous populations can lead to important differences in birth and death rates across a phylogeny. Taking this heterogeneity into account is …”
Volltext

BEAST 2.5: An advanced software platform for Bayesian evolutionary analysis von Bouckaert, Remco, Vaughan, Timothy G., Barido-Sottani, Joëlle, Duchêne, Sebastián, Fourment, Mathieu, Gavryushkina, Alexandra, Heled, Joseph, Jones, Graham, Kühnert, Denise, De Maio, Nicola, Matschiner, Michael, Mendes, Fábio K., Müller, Nicola F., Ogilvie, Huw A., du Plessis, Louis, Popinga, Alex, Rambaut, Andrew, Rasmussen, David, Siveroni, Igor, Suchard, Marc A., Wu, Chieh-Hsi, Xie, Dong, Zhang, Chi, Stadler, Tanja, Drummond, Alexei J.

“… Elaboration of Bayesian phylogenetic inference methods has continued at pace in recent years with major new advances in nearly all aspects of the joint …”
Volltext

Phylodynamics with Migration: A Computational Framework to Quantify Population Structure from Genomic Data von Kühnert, Denise, Stadler, Tanja, Vaughan, Timothy G., Drummond, Alexei J.

“… When viruses spread, outbreaks can be spawned in previously unaffected regions. Depending on the time and mode of introduction, each regional outbreak can have …”
Volltext

The origin and early spread of SARS-CoV-2 in Europe von Nadeau, Sarah A, Vaughan, Timothy G, Scire, Jérémie, Huisman, Jana S, Stadler, Tanja

“… The investigation of migratory patterns during the SARS-CoV-2 pandemic before spring 2020 border closures in Europe is a crucial first step toward an in-depth …”
Weitere Angaben

TreeKnit: Inferring ancestral reassortment graphs of influenza viruses von Barrat-Charlaix, Pierre, Vaughan, Timothy G., Neher, Richard A.

“… When two influenza viruses co-infect the same cell, they can exchange genome segments in a process known as reassortment. Reassortment is an important source …”
Volltext

Accelerated clinical discovery using self-reported patient data collected online and a patient-matching algorithm von Wicks, Paul, Vaughan, Timothy E, Massagli, Michael P, Heywood, James

“… The experiences of patients who try drugs that aren't approved for their disease have the potential to be mined for insights into drug efficacy. Wicks et al  …”
Volltext

Estimates of early outbreak-specific SARS-CoV-2 epidemiological parameters from genomic data von Vaughan, Timothy G, Scire, Jérémie, Nadeau, Sarah A, Stadler, Tanja

“… We estimate the basic reproductive number and case counts for 15 distinct Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreaks, distributed …”
Weitere Angaben

Efficient Bayesian inference under the structured coalescent von Vaughan, Timothy G., Kühnert, Denise, Popinga, Alex, Welch, David, Drummond, Alexei J.

“… Motivation: Population structure significantly affects evolutionary dynamics. Such structure may be due to spatial segregation, but may also reflect any other …”
Volltext

The effect of sequencing and assembly on the inference of horizontal gene transfer on chromosomal and plasmid phylogenies von Huisman, Jana S, Vaughan, Timothy G, Egli, Adrian, Tschudin-Sutter, Sarah, Stadler, Tanja, Bonhoeffer, Sebastian

“… The spread of antibiotic resistance genes on plasmids is a threat to human and animal health. Phylogenies of bacteria and their plasmids contain clues …”
Weitere Angaben

Applying quality control to daily habits: A new method for teaching quality control von Kabadurmus, Ozgur, Powell, Karsten, Vaughan, Timothy S.

“… This teaching brief presents a new experiential exercise for teaching statistical process control (SPC) within a quality management course. This novel approach …”
Volltext

Decoding the Fundamental Drivers of Phylodynamic Inference von Featherstone, Leo A, Duchene, Sebastian, Vaughan, Timothy G

“… Abstract Despite its increasing role in the understanding of infectious disease transmission at the applied and theoretical levels, phylodynamics lacks a …”
Volltext

The Fossilized Birth–Death Model Is Identifiable von Truman, Kate, Vaughan, Timothy G, Gavryushkin, Alex, Gavryushkina, Alexandra “Sasha”

“… Abstract Time-dependent birth–death sampling models have been used in numerous studies to infer past evolutionary dynamics in different biological contexts, …”
Volltext

Bayesian inference of reassortment networks reveals fitness benefits of reassortment in human influenza viruses von Müller, Nicola F, Stolz, Ugnė, Dudas, Gytis, Stadler, Tanja, Vaughan, Timothy G

“… Reassortment is an important source of genetic diversity in segmented viruses and is the main source of novel pathogenic influenza viruses. Despite this, …”
Weitere Angaben

Simultaneous reconstruction of evolutionary history and epidemiological dynamics from viral sequences with the birth-death SIR model von Kühnert, Denise, Stadler, Tanja, Vaughan, Timothy G, Drummond, Alexei J

“… The evolution of RNA viruses, such as human immunodeficiency virus (HIV), hepatitis C virus and influenza virus, occurs so rapidly that the viruses' genomes …”
Weitere Angaben

Sharing Health Data for Better Outcomes on PatientsLikeMe von Wicks, Paul, Massagli, Michael, Frost, Jeana, Brownstein, Catherine, Okun, Sally, Vaughan, Timothy, Bradley, Richard, Heywood, James

“… PatientsLikeMe is an online quantitative personal research platform for patients with life-changing illnesses to share their experience using patient-reported …”
Volltext

Estimating pathogen spread using structured coalescent and birth–death models: A quantitative comparison von Seidel, Sophie, Stadler, Tanja, Vaughan, Timothy G.

“… Elucidating disease spread between subpopulations is crucial in guiding effective disease control efforts. Genomic epidemiology and phylodynamics have emerged …”
Volltext