Výsledky vyhľadávania - "Vaiman, Daniel"
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Oxidative Stress in Preeclampsia and Placental Diseases
ISSN: 1422-0067, 1661-6596, 1422-0067Vydavateľské údaje: Switzerland MDPI AG 17.05.2018Vydané v International journal of molecular sciences (17.05.2018)“…Preeclampsia is a persistent hypertensive gestational disease characterized by high blood pressure and proteinuria, which presents from the second trimester of…”
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Genetic regulation of recurrent spontaneous abortion in humans
ISSN: 2319-4170, 2320-2890, 2320-2890Vydavateľské údaje: United States Medknow Publications and Media Pvt. Ltd 01.01.2015Vydané v Biomedical Journal (01.01.2015)“…Recurrent pregnancy loss, defined as a pregnancy failure occurring before 24 weeks of gestation more than two or three times according to most definitions, is…”
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Exploring the Molecular Aetiology of Preeclampsia by Massive Parallel Sequencing of DNA
ISSN: 1522-6417, 1534-3111, 1534-3111Vydavateľské údaje: New York Springer US 01.04.2020Vydané v Current hypertension reports (01.04.2020)“…Purpose of Review This manuscript aims to review (for the first time) studies describing NGS sequencing of preeclampsia (PE) women’s DNA. Recent Findings…”
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The Role of Epigenetics in Placental Development and the Etiology of Preeclampsia
ISSN: 1422-0067, 1661-6596, 1422-0067Vydavateľské údaje: Switzerland MDPI AG 11.06.2019Vydané v International journal of molecular sciences (11.06.2019)“…In this review, we comprehensively present the function of epigenetic regulations in normal placental development as well as in a prominent disease of…”
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Landscape of Transcriptional Deregulations in the Preeclamptic Placenta
ISSN: 1932-6203, 1932-6203Vydavateľské údaje: United States Public Library of Science 13.06.2013Vydané v PloS one (13.06.2013)“…Preeclampsia is a pregnancy disease affecting 5 to 8% of pregnant women and a leading cause of both maternal and fetal mortality and morbidity. Because of a…”
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An Integrative Analysis of Preeclampsia Based on the Construction of an Extended Composite Network Featuring Protein-Protein Physical Interactions and Transcriptional Relationships
ISSN: 1932-6203, 1932-6203Vydavateľské údaje: United States Public Library of Science 01.11.2016Vydané v PloS one (01.11.2016)“…Preeclampsia (PE) is a pregnancy disorder defined by hypertension and proteinuria. This disease remains a major cause of maternal and fetal morbidity and…”
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Prevention of gravidic endothelial hypertension by aspirin treatment administered from the 8th week of gestation
ISSN: 1348-4214, 1348-4214Vydavateľské údaje: England 01.10.2011Vydané v Hypertension research (01.10.2011)“…The aim of this study was to evaluate whether low doses of aspirin (100 mg per day) administered to a homogeneous population of women early (8-10 weeks) during…”
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Mutant Cohesin in Premature Ovarian Failure
ISSN: 0028-4793, 1533-4406, 1533-4406Vydavateľské údaje: Waltham, MA Massachusetts Medical Society 06.03.2014Vydané v The New England journal of medicine (06.03.2014)“…Few genes have been implicated in sporadic premature ovarian failure. This study implicates STAG3, which encodes a cohesin, a protein that mediates chromosome…”
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Sperm SPACA6 protein is required for mammalian Sperm-Egg Adhesion/Fusion
ISSN: 2045-2322, 2045-2322Vydavateľské údaje: London Nature Publishing Group UK 24.03.2020Vydané v Scientific reports (24.03.2020)“…Three genes are known to be essential for gamete adhesion/fusion ( Cd9, Izumo1 and Juno ). Here, we confirmed that Spaca6 null males are infertile and showed…”
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Oxytocin receptor agonist reduces perinatal brain damage by targeting microglia
ISSN: 0894-1491, 1098-1136, 1098-1136Vydavateľské údaje: Hoboken, USA John Wiley & Sons, Inc 01.02.2019Vydané v Glia (01.02.2019)“…Prematurity and fetal growth restriction (FGR) are frequent conditions associated with adverse neurocognitive outcomes. We have previously identified early…”
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Predictable increase in female reproductive window: A simple model connecting age of reproduction, menopause, and longevity
ISSN: 0265-9247, 1521-1878, 1521-1878Vydavateľské údaje: United States Wiley 01.05.2021Vydané v BioEssays (01.05.2021)“…With the ever‐increasing lifespan along with societal changes, women can marry and procreate later than in previous centuries. However, pathogenic genetic…”
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Novel genes and mutations in patients affected by recurrent pregnancy loss
ISSN: 1932-6203, 1932-6203Vydavateľské údaje: United States Public Library of Science 10.10.2017Vydané v PloS one (10.10.2017)“…Recurrent pregnancy loss is a frequently occurring human infertility-related disease affecting ~1% of women. It has been estimated that the cause remains…”
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Pregnancy exposure to phthalates and DNA methylation in male placenta — An epigenome-wide association study
ISSN: 0160-4120, 1873-6750, 1873-6750Vydavateľské údaje: Netherlands Elsevier Ltd 01.02.2022Vydané v Environment international (01.02.2022)“…[Display omitted] Exposure to phthalates during pregnancy may alter DNA methylation in the placenta, a crucial organ for the growth and development of the…”
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An integrated multi-tissue approach for endometriosis candidate biomarkers: a systematic review
ISSN: 1477-7827, 1477-7827Vydavateľské údaje: London BioMed Central 10.02.2024Vydané v Reproductive biology and endocrinology (10.02.2024)“…Biomarker identification could help in deciphering endometriosis pathophysiology in addition to their use in the development of non invasive diagnostic and…”
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Maternal blood pressure associates with placental DNA methylation both directly and through alterations in cell-type composition
ISSN: 1741-7015, 1741-7015Vydavateľské údaje: London BioMed Central 20.10.2022Vydané v BMC medicine (20.10.2022)“…Background Maternal blood pressure levels reflect cardiovascular adaptation to pregnancy and proper maternal-fetal exchanges through the placenta and are very…”
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Overexpression of the STOX1B isoform of STOX1 triggers preeclampsia-like symptoms through HNF4α-dependent alterations of coagulation cascades in mice
ISSN: 2045-2322, 2045-2322Vydavateľské údaje: London Nature Publishing Group UK 03.07.2025Vydané v Scientific reports (03.07.2025)“…STOX1 has been involved in genetic forms of preeclampsia. The gene encodes two major isoforms coined STOX1A and STOX1B (989 and 227 amino-acids, respectively),…”
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Long-term cardiovascular disorders in the STOX1 mouse model of preeclampsia
ISSN: 2045-2322, 2045-2322Vydavateľské údaje: London Nature Publishing Group UK 15.08.2019Vydané v Scientific reports (15.08.2019)“…Adverse long-term cardiovascular (CV) consequences of PE are well established in women. However, the mechanism responsible for that risk remains unknown. Here,…”
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The Impact of Oxidative Stress of Environmental Origin on the Onset of Placental Diseases
ISSN: 2076-3921, 2076-3921Vydavateľské údaje: Switzerland MDPI AG 01.01.2022Vydané v Antioxidants (01.01.2022)“…Oxidative stress (OS) plays a pivotal role in placental development; however, abnormal loads in oxidative stress molecules may overwhelm the placental defense…”
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A Genetic Basis for a Postmeiotic X Versus Y Chromosome Intragenomic Conflict in the Mouse
ISSN: 1553-7404, 1553-7390, 1553-7404Vydavateľské údaje: United States Public Library of Science 01.09.2012Vydané v PLoS genetics (01.09.2012)“…Intragenomic conflicts arise when a genetic element favours its own transmission to the detriment of others. Conflicts over sex chromosome transmission are…”
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Hepatic transcriptome and DNA methylation patterns following perinatal and chronic BPS exposure in male mice
ISSN: 1471-2164, 1471-2164Vydavateľské údaje: London BioMed Central 09.12.2020Vydané v BMC genomics (09.12.2020)“…Background Bisphenol S (BPS) is a common bisphenol A (BPA) substitute, since BPA is virtually banned worldwide. However, BPS and BPA have both endocrine…”
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