Výsledky vyhledávání - "Up-Regulation"

Quercetin modulates OTA-induced oxidative stress and redox signalling in HepG2 cells — up regulation of Nrf2 expression and down regulation of NF-κB and COX-2 Autor Ramyaa, Periasamy, krishnaswamy, Rajashree, Padma, Viswanadha Vijaya

“…Ochratoxin A (OTA), a mycotoxin, causes extensive cell damage, affecting liver and kidney cells. OTA toxicity is fairly well characterized where oxidative…”
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Up-regulation of PPAR-gamma mRNA expression in the liver of obese patients: an additional reinforcing lipogenic mechanism to SREBP-1c induction Autor Pettinelli, Paulina, Videla, Luis A

“…Triglyceride accumulation in the liver is an early feature in the development of nonalcoholic fatty liver disease (NAFLD) associated with human obesity, which…”
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Role of NF-κB activation and VEGF gene polymorphisms in VEGF up regulation in non-proliferative and proliferative diabetic retinopathy Autor Choudhuri, Subhadip, Chowdhury, Imran H., Das, Shibali, Dutta, Deep, Saha, Avijit, Sarkar, Rajarshi, Mandal, Lakshmi K., Mukherjee, Satinath, Bhattacharya, Basudev

“…) activation and downstream up-regulation of vascular endothelial growth factor (VEGF) in diabetic retinopathy (DR…”
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[11C]Metoclopramide PET can detect a seizure-induced up-regulation of cerebral P-glycoprotein in epilepsy patients Autor Biali, Myriam El, Breuil, Louise, Jackwerth, Matthias, Mairinger, Severin, Weber, Maria, Wölfl-Duchek, Michael, Bamminger, Karsten, Rausch, Ivo, Nics, Lukas, Hacker, Marcus, Rodrigo, Sebastian, Bouilleret, Viviane, Zeitlinger, Markus, Pataraia, Ekaterina, Tournier, Nicolas, Bauer, Martin, Langer, Oliver

“…) as a model disease with a well characterised, regional P-gp up-regulation at the BBB. Methods Eight patients with drug-resistant (DRE…”
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Up‐regulation of HOXA‐AS2 and MEG3 long non‐coding RNAs acts as a potential peripheral biomarker for bipolar disorder Autor Hosseini, Maryam, Mokhtari, Mohammad Javad

“…Bipolar disorder (BD) is a psychiatric condition that is frequently misdiagnosed and linked to inadequate treatment. Long non‐coding RNAs (lncRNAs) have lately…”
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Up-regulation of the complement system in subcutaneous adipocytes from nonobese, hypertriglyceridemic subjects is associated with adipocyte insulin resistance Autor van Greevenbroek, M M J, Ghosh, S, van der Kallen, C J H, Brouwers, M C G J, Schalkwijk, C G, Stehouwer, C D A

“… The aim of the study was to identify differentially regulated pathways in sc adipocytes of dyslipidemic subjects…”
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Up-regulation of human immune system function by Donkey’s Milk Autor Taghiloo, Saeid, Allahmoradi, Esmaeil, Sadeghian-Kiadehi, Seyedeh Forough, Omrani-Nava, Versa, Nazar, Eisa, Ebrahimzadeh, Mohammad Ali

“…). PBMCs were isolated from 12 young and 12 aged normal subjects. PBMCs were cultured with or without the optimal and non-cytotoxic dose of pasteurized…”
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HIV-mediated up-regulation of invariant chain (CD74) correlates with generalized immune activation in HIV+ subjects Autor Ghiglione, Yanina, Rodríguez, Ana María, De Candia, Cristian, Carobene, Mauricio, Benaroch, Philippe, Schindler, Michael, Salomón, Horacio, Turk, Gabriela

“…HIV Nef-mediated up-regulation of invariant chain (Ii chain, also CD74) is presumed to play an active role in HIV immunopathogenesis…”
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miR146a up-regulation is involved in small HA oligosaccharides-induced pro-inflammatory response in human chondrocytes Autor Avenoso, Angela, D'Ascola, Angela, Scuruchi, Michele, Mandraffino, Giuseppe, Campo, Salvatore, Campo, Giuseppe M.

“…Small HA fragments are produced during cartilage degradation and their role seems to be preponderant during pathologies in which cartilage injury contribute to…”
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Up regulation of monocyte chemoattractant protein-1 expression in anti-citrulline antibody and immunoglobulin M rheumatoid factor positive subjects precedes onset of inflammatory response and development of overt rheumatoid arthritis Autor Rantapää-Dahlqvist, S, Boman, K, Tarkowski, A, Hallmans, G

“…Objective: To analyse the inflammatory mediators, including monocyte chemoattractant protein-1 (MCP-1), in blood samples donated years before onset of…”
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Atherogenic effects of TNF-α and IL-6 via up-regulation of scavenger receptors Autor Hashizume, Misato, Mihara, Masahiko

“…IL-6R Ab partially inhibited TNF-α-induced oxLDL accumulation. ► Serum from RA patients, but not serum of healthy subjects, induced foam cell formation…”
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Up-regulation of miR-182 by β-catenin in breast cancer increases tumorigenicity and invasiveness by targeting the matrix metalloproteinase inhibitor RECK Autor Chiang, Chi-Hsiang, Hou, Ming-Feng, Hung, Wen-Chun

“…MiR-182 is a member of the miR-183 cluster located at human chromosome 7q32 region and is up-regulated in human cancers. We study the regulation of miR-182…”
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Differential up-regulation of neurotrophin receptors and functional activity of neurotrophins on peripheral blood eosinophils of patients with allergic rhinitis, atopic dermatitis and nonatopic subjects Autor Raap, U., Deneka, N., Bruder, M., Kapp, A., Wedi, B.

“… Indeed, in contrast to nonatopic subjects (NA), neurotrophins have been shown to be increased in atopic diseases such as allergic rhinitis (AR…”
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Significant up-regulation of lncRNAs in neuromyelitis optica spectrum disorder Autor Taheri, Mohammad, Sadeghi, Ahmad, Gharebaghi, Alireza, Ghiasian, Masoud, Eslami, Solat, Khalilian, Sheyda, Sayad, Arezou, Ghafouri-Fard, Soudeh

“… MEG3 had the most robust over-expression in patients subgroups compared with normal subjects…”
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Interleukin‐10 responses from acute exercise in healthy subjects: A systematic review Autor Cabral‐Santos, Carolina, Lima Junior, Edson Alves, Fernandes, Isabela Maia da Cruz, Pinto, Rafael Zambelli, Rosa‐Neto, José César, Bishop, Nicolette Charllote, Lira, Fábio Santos

“…Purpose Interleukin 10 (IL‐10) is a cytokine that plays a critical role with potent anti‐inflammatory properties when produced during exercise, limiting host…”
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Role of Complex Epigenetic Switching in Tumor Necrosis Factor-α Upregulation in the Prefrontal Cortex of Suicide Subjects Autor Wang, Qingzhong, Roy, Bhaskar, Turecki, Gustavo, Shelton, Richard C, Dwivedi, Yogesh

“…Proinflammatory cytokines have recently received considerable attention for their role in suicidal behavior; however, how the expression of cytokine genes is…”
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Up‐regulation of transient receptor potential vanilloid (TRPV) and down‐regulation of brain‐derived neurotrophic factor (BDNF) expression in patients with functional dyspepsia (FD) Autor Cheung, C. K. Y., Lan, L. L., Kyaw, M., Mak, A. D. P., Chan, A., Chan, Y., Wu, J. C. Y.

“… Subjects with GERD and IBS as predominant symptoms, diabetes mellitus, current or previous Helicobacter pylori infection, psychiatric illness and recent use of NSAID or PPI were excluded…”
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Up-Regulation of microRNA-126 May Contribute to Pathogenesis of Ulcerative Colitis via Regulating NF-kappaB Inhibitor IκBα Autor Feng, Xiao, Wang, Hao, Ye, Shicai, Guan, Jiaxi, Tan, Wenkai, Cheng, Si, Wei, Guoli, Wu, Weiyun, Wu, Feng, Zhou, Yu

“…) and from healthy subjects by quantitative RT-PCR and immunofluorescence analyses. Regulation of gene expression by miR-126 was assessed using luciferase reporter construct assays and specific miRNA mimic transfection…”
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Blue light induces the nuclear translocation of neuropeptide receptor PAC1-R associated with the up-regulation of PAC1-R its own in reactive oxygen species associated way Autor Yu, Rongjie, Lin, Zhuochao, Ouyang, Zehua, Tao, Zhengxin, Fan, Guangchun

“… was positive correlation with the up-regulation of expression level and promoter activity of PAC1-R…”
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Longitudinal up‐regulation of endolymphatic hydrops in patients with Meniere's disease during medical treatment Autor Fukushima, Munehisa, Kitahara, Tadashi, Oya, Ryohei, Akahani, Shiro, Inohara, Hidenori, Naganawa, Shinji, Takeda, Noriaki

“…‐arm repeated measures Methods Eleven MD patients were enrolled. All subjects prospectively underwent gadolinium…”
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