Výsledky vyhledávání - "Type III Secretion Systems/genetics"

A gut-vascular barrier controls the systemic dissemination of bacteria Autor Spadoni, Ilaria, Zagato, Elena, Bertocchi, Alice, Paolinelli, Roberta, Hot, Edina, Di Sabatino, Antonio, Caprioli, Flavio, Bottiglieri, Luca, Oldani, Amanda, Viale, Giuseppe, Penna, Giuseppe, Dejana, Elisabetta, Rescigno, Maria

“…In healthy individuals, the intestinal microbiota cannot access the liver, spleen, or other peripheral tissues. Some pathogenic bacteria can reach these sites,…”
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Type III secretion systems: the bacterial flagellum and the injectisome Autor Diepold, Andreas, Armitage, Judith P

“…The flagellum and the injectisome are two of the most complex and fascinating bacterial nanomachines. At their core, they share a type III secretion system…”
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Salmonella Typhimurium reprograms macrophage metabolism via T3SS effector SopE2 to promote intracellular replication and virulence Autor Jiang, Lingyan, Wang, Peisheng, Song, Xiaorui, Zhang, Huan, Ma, Shuangshuang, Wang, Jingting, Li, Wanwu, Lv, Runxia, Liu, Xiaoqian, Ma, Shuai, Yan, Jiaqi, Zhou, Haiyan, Huang, Di, Cheng, Zhihui, Yang, Chen, Feng, Lu, Wang, Lei

“…Salmonella Typhimurium establishes systemic infection by replicating in host macrophages. Here we show that macrophages infected with S . Typhimurium exhibit…”
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The type III secretion system effector network hypothesis Autor Sanchez-Garrido, Julia, Ruano-Gallego, David, Choudhary, Jyoti S., Frankel, Gad

“…Type III secretion system (T3SS) effectors are key virulence factors that underpin the infection strategy of many clinically important Gram-negative pathogens,…”
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Agrobacterium expressing a type III secretion system delivers Pseudomonas effectors into plant cells to enhance transformation Autor Raman, Vidhyavathi, Rojas, Clemencia M., Vasudevan, Balaji, Dunning, Kevin, Kolape, Jaydeep, Oh, Sunhee, Yun, Jianfei, Yang, Lishan, Li, Guangming, Pant, Bikram D., Jiang, Qingzhen, Mysore, Kirankumar S.

“…Agrobacterium -mediated plant transformation (AMT) is the basis of modern-day plant biotechnology. One major drawback of this technology is the recalcitrance…”
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An Arabidopsis Secondary Metabolite Directly Targets Expression of the Bacterial Type III Secretion System to Inhibit Bacterial Virulence Autor Wang, Wei, Yang, Jing, Zhang, Jian, Liu, Yong-Xin, Tian, Caiping, Qu, Baoyuan, Gao, Chulei, Xin, Peiyong, Cheng, Shujing, Zhang, Wenjing, Miao, Pei, Li, Lei, Zhang, Xiaojuan, Chu, Jinfang, Zuo, Jianru, Li, Jiayang, Bai, Yang, Lei, Xiaoguang, Zhou, Jian-Min

“…Plants deploy a variety of secondary metabolites to fend off pathogen attack. Although defense compounds are generally considered toxic to microbes, the exact…”
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Phylogenomics characterization of a highly virulent Edwardsiella strain ET080813(T) encoding two distinct T3SS and three T6SS gene clusters: Propose a novel species as Edwardsiella anguillarum sp. nov Autor Shao, Shuai, Lai, Qiliang, Liu, Qin, Wu, Haizhen, Xiao, Jingfan, Shao, Zongze, Wang, Qiyao, Zhang, Yuanxing

“…As important zoonotic organisms causing infections in humans, Edwardsiella bacteria are also notorious leading fish pathogens haunting worldwide aquaculture…”
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Type III secretion system effectors form robust and flexible intracellular virulence networks Autor Ruano-Gallego, David, Sanchez-Garrido, Julia, Kozik, Zuzanna, Núñez-Berrueco, Elena, Cepeda-Molero, Massiel, Mullineaux-Sanders, Caroline, Naemi Baghshomali, Yasaman, Slater, Sabrina L, Wagner, Naama, Glegola-Madejska, Izabela, Roumeliotis, Theodoros I, Pupko, Tal, Fernández, Luis Ángel, Rodríguez-Patón, Alfonso, Choudhary, Jyoti S, Frankel, Gad

“…Infections with many Gram-negative pathogens, including , , , and , rely on type III secretion system (T3SS) effectors. We hypothesized that while hijacking…”
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Edwardsiella piscicida: A versatile emerging pathogen of fish Autor Leung, Ka Yin, Wang, Qiyao, Yang, Zhiyun, Siame, Bupe A.

“…Edwardsiella piscicida is an Enterobacteriaceae that is abundant in water and causes food and waterborne infections in fish, animals, and humans. The bacterium…”
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Pathogenic diversification of the gut commensal Providencia alcalifaciens via acquisition of a second type III secretion system Autor Klein, Jessica A, Predeus, Alexander V, Greissl, Aimee R, Clark-Herrera, Mattie M, Cruz, Eddy, Cundiff, Jennifer A, Haeberle, Amanda L, Howell, Maya, Lele, Aaditi, Robinson, Donna J, Westerman, Trina L, Wrande, Marie, Wright, Sarah J, Green, Nicole M, Vallance, Bruce A, McClelland, Michael, Mejia, Andres, Goodman, Alan G, Elfenbein, Johanna R, Knodler, Leigh A

“…is a Gram-negative bacterium found in various water and land environments and organisms, including insects and mammals. Some strains encode gene homologs of…”
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Overexpression of T3SS translocation signals in Salmonella causes delayed attenuation Autor Abele, Taylor J, Billman, Zachary P, Harvest, Carissa K, Bryan, Alexia K, Larson, Heather N, Coers, Jörn, Miao, Edward A

“…Engineering pathogens is a useful method for discovering new details of microbial pathogenesis and host defense. However, engineering can result in off-target…”
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Discovery of the Hrp Type III Secretion System in Phytopathogenic Bacteria: How Investigation of Hypersensitive Cell Death in Plants Led to a Novel Protein Injector System and a World of Inter-Organismal Molecular Interactions Within Plant Cells Autor Kvitko, Brian H, Collmer, Alan

“…In the early 1960s, and other host-specific phytopathogenic proteobacteria were discovered to elicit a rapid, resistance-associated death when infiltrated at…”
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TIR-only protein RBA1 recognizes a pathogen effector to regulate cell death in Arabidopsis Autor Nishimura, Marc T, Anderson, Ryan G, Cherkis, Karen A, Law, Terry F, Liu, Qingli L, Machius, Mischa, Nimchuk, Zachary L, Yang, Li, Chung, Eui-Hwan, El Kasmi, Farid, Hyunh, Michael, Osborne Nishimura, Erin, Sondek, John E, Dangl, Jeffery L

“…Detection of pathogens by plants is mediated by intracellular nucleotide-binding site leucine-rich repeat (NLR) receptor proteins. NLR proteins are defined by…”
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Variation in bradyrhizobial NopP effector determines symbiotic incompatibility with Rj2-soybeans via effector-triggered immunity Autor Sugawara, Masayuki, Takahashi, Satoko, Umehara, Yosuke, Iwano, Hiroya, Tsurumaru, Hirohito, Odake, Haruka, Suzuki, Yuta, Kondo, Hitoshi, Konno, Yuki, Yamakawa, Takeo, Sato, Shusei, Mitsui, Hisayuki, Minamisawa, Kiwamu

“…Genotype-specific incompatibility in legume–rhizobium symbiosis has been suggested to be controlled by effector-triggered immunity underlying pathogenic…”
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NAIP proteins are required for cytosolic detection of specific bacterial ligands in vivo Autor Rauch, Isabella, Tenthorey, Jeannette L, Nichols, Randilea D, Al Moussawi, Khatoun, Kang, James J, Kang, Chulho, Kazmierczak, Barbara I, Vance, Russell E

“…NLRs (nucleotide-binding domain [NBD] leucine-rich repeat [LRR]-containing proteins) exhibit diverse functions in innate and adaptive immunity. NAIPs (NLR…”
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Effectidor II: a pan-genomic AI-based algorithm for the prediction of type III secretion system effectors Autor Wagner, Naama, Baumer, Ella, Lyubman, Iris, Shimony, Yair, Bracha, Noam, Martins, Leonor, Potnis, Neha, Chang, Jeff H, Teper, Doron, Koebnik, Ralf, Pupko, Tal

“…Type III secretion systems are used by many Gram-negative bacteria to inject type 3 effectors (T3Es) directly into eukaryotic cells, promoting disease or…”
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A widespread plant defense compound disarms bacterial type III injectisome assembly Autor Miao, Pei, Wang, Haijun, Wang, Wei, Wang, Zhengdong, Ke, Han, Cheng, Hangyuan, Ni, Jinjing, Liang, Jingnan, Yao, Yu-Feng, Wang, Jizong, Zhou, Jian-Min, Lei, Xiaoguang

“…Numerous gram-negative bacterial pathogens employ the type III secretion system (T3SS), a multiprotein injectisome, to deliver virulence proteins into host…”
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FlaG competes with FliS-flagellin complexes for access to FlhA in the flagellar T3SS to control Campylobacter jejuni filament length Autor Waller, Alexis A, Ribardo, Deborah A, Hendrixson, David R

“…Bacteria power rotation of an extracellular flagellar filament for swimming motility. Thousands of flagellin subunits compose the flagellar filament, which…”
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Conserved effectors underpin the virulence of liverwort-isolated Pseudomonas in divergent plants Autor Robinson, Kayla, Buric, Lucia, Grenz, Kristina, Chia, Khong-Sam, Hulin, Michelle T, Ma, Wenbo, Carella, Philip

“…Plant pathogenic Pseudomonas species naturally antagonize a diverse range of flowering plants. While emerging research demonstrates that isolates belonging to…”
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Shigella sonnei Autor Torraca, Vincenzo, Holt, Kathryn, Mostowy, Serge

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