Search Results - "Tumor Microenvironment"

Fibroblasts in the Tumor Microenvironment by Truffi, Marta, Sorrentino, Luca, Corsi, Fabio

“…The implications of a tumor microenvironment in cancer initiation and progression have drawn interest in recent years…”
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Persistent Regulation of Tumor Microenvironment via Circulating Catalysis of MnFe2O4@Metal–Organic Frameworks for Enhanced Photodynamic Therapy by Yin, Sheng‐Yan, Song, Guosheng, Yang, Yue, Zhao, Yan, Wang, Peng, Zhu, Long‐Min, Yin, Xia, Zhang, Xiao‐Bing

“…), is subject to the hypoxia and overexpressed glutathione (GSH) found in the tumor microenvironment (TME…”
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PD-L1+MDSCs are increased in HCC patients and induced by soluble factor in the tumor microenvironment by Iwata, Tomoaki, Kondo, Yasuteru, Kimura, Osamu, Morosawa, Tatsuki, Fujisaka, Yasuyuki, Umetsu, Teruyuki, Kogure, Takayuki, Inoue, Jun, Nakagome, Yu, Shimosegawa, Tooru

“… PBMCs from HCC patients contained significantly higher percentages of PD-L1 + MDSCs in comparison to those from healthy subjects ( p  < 0.001…”
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FAP Promotes Immunosuppression by Cancer-Associated Fibroblasts in the Tumor Microenvironment via STAT3-CCL2 Signaling by Yang, Xuguang, Lin, Yuli, Shi, Yinghong, Li, Bingji, Liu, Weiren, Yin, Wei, Dang, Yongjun, Chu, Yiwei, Fan, Jia, He, Rui

“…Cancer-associated fibroblasts (CAF) are components of the tumor microenvironment whose contributions to malignant progression are not fully understood…”
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Challenges in glioblastoma research: focus on the tumor microenvironment by Bikfalvi, Andreas, da Costa, Cristine Alves, Avril, Tony, Barnier, Jean-Vianney, Bauchet, Luc, Brisson, Lucie, Cartron, Pierre Francois, Castel, Hélène, Chevet, Eric, Chneiweiss, Hervé, Clavreul, Anne, Constantin, Bruno, Coronas, Valérie, Daubon, Thomas, Dontenwill, Monique, Ducray, Francois, Enz-Werle, Natacha, Figarella-Branger, Dominique, Fournier, Isabelle, Frenel, Jean-Sébastien, Gabut, Mathieu, Galli, Thierry, Gavard, Julie, Huberfeld, Gilles, Hugnot, Jean-Philippe, Idbaih, Ahmed, Junier, Marie-Pierre, Mathivet, Thomas, Menei, Philippe, Meyronet, David, Mirjolet, Céline, Morin, Fabrice, Mosser, Jean, Moyal, Elisabeth Cohen-Jonathan, Rousseau, Véronique, Salzet, Michel, Sanson, Marc, Seano, Giorgio, Tabouret, Emeline, Tchoghandjian, Aurélie, Turchi, Laurent, Vallette, Francois M, Vats, Somya, Verreault, Maité, Virolle, Thierry

“… In recent years, the tumor microenvironment (TME) has been recognized as an important player and therapeutic target in GBM…”
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Tumor Microenvironment: A Metabolic Player that Shapes the Immune Response by Cassim, Shamir, Pouyssegur, Jacques

“… Unlike cancer cells, immune cells are not subject to a “Darwinian evolutionary pressure…”
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Heparan Sulfate Proteoglycan Signaling in Tumor Microenvironment by De Pasquale, Valeria, Pavone, Luigi Michele

“…In the last few decades, heparan sulfate (HS) proteoglycans (HSPGs) have been an intriguing subject of study for their complex structural characteristics…”
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Tumor Microenvironment Responsive “Head-to-Foot” Self-Assembly Nanoplatform for Positron Emission Tomography Imaging in Living Subjects by Qiu, Ling, Li, Ke, Dong, Wenyi, Seimbille, Yann, Liu, Qingzhu, Gao, Feng, Lin, Jianguo

“…Sensitivity and specificity of molecular probes are two important factors in determining the accuracy of cancer diagnosis or the efficacy of cancer treatment…”
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Melanoma cell–derived exosomes promote epithelial–mesenchymal transition in primary melanocytes through paracrine/autocrine signaling in the tumor microenvironment by Xiao, Deyi, Barry, Samantha, Kmetz, Daniel, Egger, Michael, Pan, Jianmin, Rai, Shesh N., Qu, Jifu, McMasters, Kelly M., Hao, Hongying

“…•Targeting exosome-mediated EMT may be an approach to prevent tumor progression. The tumor microenvironment is abundant with exosomes that are secreted by the cancer cells themselves…”
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Lactate Contribution to the Tumor Microenvironment: Mechanisms, Effects on Immune Cells and Therapeutic Relevance by Romero-Garcia, Susana, Moreno-Altamirano, María Maximina B., Prado-Garcia, Heriberto, Sánchez-García, Francisco Javier

“… Besides tumor cells, stromal cells are another source of lactate production in the tumor microenvironment, whose role in both tumor growth and the antitumor immune response is the subject of intense research…”
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SFRP2 augments WNT16B signaling to promote therapeutic resistance in the damaged tumor microenvironment by Sun, Y, Zhu, D, Chen, F, Qian, M, Wei, H, Chen, W, Xu, J

“… The tumor microenvironment (TME) is a major barrier to clinical success by compromising therapeutic efficacy, and pathological relevance of multiple soluble factors released by a therapeutically remodeled TME remains largely unexplored…”
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Bone marrow-derived mesenchymal stem cells and the tumor microenvironment by Bergfeld, Scott A., DeClerck, Yves A.

“…Over the last decade, there has been a growing interest in the role of mesenchymal stem cells (MSC) in cancer progression. These cells have the potential to…”
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Tumor microenvironment of metastasis and risk of distant metastasis of breast cancer by Rohan, Thomas E, Xue, Xiaonan, Lin, Hung-Mo, D'Alfonso, Timothy M, Ginter, Paula S, Oktay, Maja H, Robinson, Brian D, Ginsberg, Mindy, Gertler, Frank B, Glass, Andrew G, Sparano, Joseph A, Condeelis, John S, Jones, Joan G

“…Tumor microenvironment of metastasis (TMEM), consisting of direct contact between a macrophage, an endothelial cell, and a tumor cell, has been associated with metastasis in both rodent mammary tumors and human breast cancer…”
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Tumor microenvironment responsive nanozymes for multimodal imaging of tumors by Heng Wang, Wenrui Ouyang, Hongxing Liu

“… This review provides an overview of recent studies over the past five years on the application of nanozymes capable of responding to the tumor microenvironment (TME…”
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Can cancer cells inform us about the tumor microenvironment? by Nævdal, Geir, Evje, Steinar

“…Characteristics of the tumor microenvironment (TME) such as the leaky intratumoral vascular network and the density and composition of the desmoplastic extracellular matrix (ECM…”
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Involvement of Galectin-1 Tumor Microenvironment in Radiosensitivity by CHEN, YI-FAN, WANG, CHUNG-CHI, HSU, CHIEH-YING, HUANG, ENG-YEN

“… We, therefore, aimed to investigate the role of the galectin-1 tumor microenvironment on radiosensitivity in a murine tumor model…”
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Modulation of the Tumor Microenvironment by Microbiota-Derived Short-Chain Fatty Acids: Impact in Colorectal Cancer Therapy by Gomes, Sara, Rodrigues, Ana Catarina, Pazienza, Valerio, Preto, Ana

“…). The tumor microenvironment is composed by non-cellular components, microbiota, and a great diversity of cells, such as immune cells…”
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Nerve-tumor crosstalk in tumor microenvironment: From tumor initiation and progression to clinical implications by Zhang, Zheng, Lv, Zhen Gang, Lu, Miao, Li, Haifeng, Zhou, Jiahua

“… In addition, the dynamic interaction between nerve and tumor cells in the tumor microenvironment also regulate tumor progression…”
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Immunophenotypic changes in the tumor and tumor microenvironment during progression to multiple myeloma by Bergiers, Isabelle, Köse, Murat Cem, Skerget, Sheri, Malfait, Milan, Fourneau, Nele, Ellis, Jenna-Claire, Vanhoof, Greet, Smets, Tina, Verbist, Bie, De Maeyer, Dries, Van Houdt, Jeroen, Van der Borght, Koen, Verona, Raluca, Heidrich, Bradley, Kurth, William, Delforge, Michel, Meuleman, Nathalie, Van Droogenbroeck, Jan, Vlummens, Philip, Heuck, Christoph J., Beguin, Yves, Bahlis, Nizar, Casneuf, Tineke, Caers, Jo

“…) mononuclear cell samples was used to study molecular changes in tumor cells and the tumor microenvironment (TME…”
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Leptin in Tumor Microenvironment by Angelucci, Adriano, Clementi, Letizia, Alesse, Edoardo

“… Current knowledge indicates that also different non-tumoral cells resident in tumor microenvironment may respond to leptin creating a favorable soil for cancer cells…”
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