Suchergebnisse - "Tissue Array Analysis/statistics & numerical data"

Digital quantitative assessment of PD-L1 using digital spatial profiling von Gupta, Swati, Zugazagoitia, Jon, Martinez-Morilla, Sandra, Fuhrman, Kit, Rimm, David L.

“… The assessment of programmed death 1 ligand 1 (PD-L1) expression by Immunohistochemistry (IHC) is the US Food and Drug Administration (FDA)-approved predictive …”
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Distinct blood transcriptomic signature of treatment in latent tuberculosis infected individuals at risk of developing active disease von Burel, Julie G., Singhania, Akul, Dubelko, Paige, Muller, Julius, Tanner, Rachel, Parizotto, Eneida, Dedicoat, Martin, Fletcher, Thomas E., Dunbar, James, Cunningham, Adam F., Lindestam Arlehamn, Cecilia S., Catanzaro, Donald G., Catanzaro, Antonino, Rodwell, Timothy, McShane, Helen, O'Shea, Matthew K., Peters, Bjoern

“… Although only a small fraction will ever develop the active form of tuberculosis (ATB) disease, chemoprophylaxis treatment in latent TB infected (LTBI) …”
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Prenatal chromosome microarray: ‘The UK experience’. A survey of reporting practices in UK genetic services (2012–2019) von Patterson, Jenny, Wellesley, Diana, Morgan, Sian, Cilliers, Deirdre, Allen, Stephanie, Gardiner, Carol A

“… Background The value of chromosome microarray (CMA) in the prenatal detection of significant chromosome anomalies is well‐established. To guide the …”
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Platform for Quantitative Evaluation of Spatial Intratumoral Heterogeneity in Multiplexed Fluorescence Images von Spagnolo, Daniel M, Al-Kofahi, Yousef, Zhu, Peihong, Lezon, Timothy R, Gough, Albert, Stern, Andrew M, Lee, Adrian V, Ginty, Fiona, Sarachan, Brion, Taylor, D Lansing, Chennubhotla, S Chakra

“… We introduce THRIVE (Tumor Heterogeneity Research Interactive Visualization Environment), an open-source tool developed to assist cancer researchers in …”
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Guidelines and considerations for conducting experiments using tissue microarrays von Ilyas, Mohammad, Grabsch, Heike, Ellis, Ian O, Womack, Chris, Brown, Robert, Berney, Dan, Fennell, Dean, Salto-Tellez, Manuel, Jenkins, Martin, Landberg, Goran, Byers, Richard, Treanor, Darren, Harrison, David, Green, Andrew R, Ball, Graham, Hamilton, Peter

“… Tissue microarrays (TMAs) represent a powerful method for undertaking large‐scale tissue‐based biomarker studies. While TMAs offer several advantages, there …”
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CDH17 Is a More Sensitive Marker for Gastric Adenocarcinoma Than CK20 and CDX2 von Altree-Tacha, David, Tyrrell, Jillian, Haas, Thomas

“… Context.— CDH17, which is expressed in the intestinal epithelium, is a novel oncogene involved in tumor invasion and metastasis. A panel consisting of …”
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Abnormal nuchal translucency followed by normal microarray analysis is associated with placental pathology‐related complications von Krispin, Eyal, Kushnir, Anya, Shemer, Asaf, Rienstein, Shlomit, Berkenstadt, Michal, Yinon, Yoav, Weisz, Boaz

“… Objective Identify placental pathology‐related complications, labor and neonatal outcomes in pregnancies complicated by pathological nuchal translucency (NT) …”
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High scavenger receptor class B type I expression is related to tumor aggressiveness and poor prognosis in breast cancer von Yuan, Baoying, Wu, Changshun, Wang, Xingwen, Wang, Dan, Liu, Huiling, Guo, Ling, Li, Xiang-An, Han, Junqing, Feng, Hong

“… Scavenger receptor class B type I (SR-BI) has been linked to the development and progression of breast cancer. However, its clinical significance in breast …”
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Distinct distribution and prognostic significance of molecular subtypes of breast cancer in Chinese women: a population-based cohort study von Su, Yinghao, Zheng, Ying, Zheng, Wei, Gu, Kai, Chen, Zhi, Li, Guoliang, Cai, Qiuyin, Lu, Wei, Shu, Xiao Ou

“… Background Molecular classification of breast cancer is an important prognostic factor. The distribution of molecular subtypes of breast cancer and their …”
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BTN3A2 Expression in Epithelial Ovarian Cancer Is Associated with Higher Tumor Infiltrating T Cells and a Better Prognosis von Le Page, Cécile, Marineau, Alexandre, Bonza, Patrick K., Rahimi, Kurosh, Cyr, Louis, Labouba, Ingrid, Madore, Jason, Delvoye, Nathalie, Mes-Masson, Anne-Marie, Provencher, Diane M., Cailhier, Jean-François

“… BTN3A2/BT3.2 butyrophilin mRNA expression by tumoral cells was previously identified as a prognostic factor in a small cohort of high grade serous epithelial …”
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Low PIP4K2B expression in human breast tumors correlates with reduced patient survival: A role for PIP4K2B in the regulation of E-cadherin expression von Keune, Willem-Jan, Sims, Andrew H, Jones, David R, Bultsma, Yvette, Lynch, James T, Jirström, Karin, Landberg, Goran, Divecha, Nullin

“… Phosphatidylinositol-5-phosphate (PtdIns5P) 4-kinase β (PIP4K2B) directly regulates the levels of two important phosphoinositide second messengers, PtdIns5P …”
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High chondroitin sulfate proteoglycan 4 expression correlates with poor outcome in patients with breast cancer von Hsu, Nicholas C., Nien, Pei-Yung, Yokoyama, Kazunari K., Chu, Pei-Yi, Hou, Ming-Feng

“… •We investigate the expression and significance of CSPG4 in breast cancer.•High CSPG4 expression is not related to triple-negative status of breast …”
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Abnormalities of the TITF-1 lineage-specific oncogene in NSCLC: implications in lung cancer pathogenesis and prognosis von Tang, Ximing, Kadara, Humam, Behrens, Carmen, Liu, Diane D, Xiao, Yun, Rice, David, Gazdar, Adi F, Fujimoto, Junya, Moran, Cesar, Varella-Garcia, Marileila, Lee, J Jack, Hong, Waun Ki, Wistuba, Ignacio I

“… Emerging evidence suggests that aberrant expression of oncogenes contributes to development of lung malignancy. The thyroid transcription factor 1 (TITF-1) …”
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HER2/neu Testing in Gastric Cancer by Immunohistochemistry: Assessment of Interlaboratory Variation von Sheffield, Brandon S., Garratt, John, Kalloger, Steve E., Li-Chang, Hector H., Torlakovic, Emina E., Gilks, C. Blake, Schaeffer, David F.

“… Immunohistochemical (IHC) testing for HER2/neu is becoming the standard of care for guiding adjuvant treatment of gastric carcinoma with trastuzumab. To assess …”
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Neutrophil Gelatinase-Associated Lipocalin (NGAL) Predicts Response to Neoadjuvant Chemotherapy and Clinical Outcome in Primary Human Breast Cancer von Wenners, Antonia Sophie, Mehta, Keyur, Loibl, Sibylle, Park, Hyerim, Mueller, Berit, Arnold, Norbert, Hamann, Sigrid, Weimer, Joerg, Ataseven, Beyhan, Darb-Esfahani, Silvia, Schem, Christian, Mundhenke, Christoph, Khandan, Fariba, Thomssen, Christoph, Jonat, Walter, Holzhausen, Hans-Juergen, von Minckwitz, Gunther, Denkert, Carsten, Bauer, Maret

“… In our previous work we showed that NGAL, a protein involved in the regulation of proliferation and differentiation, is overexpressed in human breast cancer …”
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Large-scale independent validation of the nuclear factor-kappa B p65 prognostic biomarker in prostate cancer von Gannon, Philippe O., Lessard, Laurent, Stevens, Louis-Mathieu, Forest, Valérie, Bégin, Louis R., Minner, Sarah, Tennstedt, Pierre, Schlomm, Thorsten, Mes-Masson, Anne-Marie, Saad, Fred

“… Over the last decade, we and others have uncovered a robust association between the nuclear localisation of nuclear factor-kappa B (NF-κB) p65, prostate cancer …”
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Expression of pim-1 in Tumors, Tumor Stroma and Tumor-Adjacent Mucosa Co-Determines the Prognosis of Colon Cancer Patients von Peng, Yong-hai, Li, Jian-jun, Xie, Fang-wei, Chen, Jian-fang, Yu, Ying-hao, Ouyang, Xue-nong, Liang, Hou-jie

“… Provirus integration site for Moloney murine leukemia virus (pim-1) is a proto-oncogene that is linked to the development and progression of several cancers …”
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Comparison of methods for handling missing data on immunohistochemical markers in survival analysis of breast cancer von Ali, A M G, Dawson, S-J, Blows, F M, Provenzano, E, Ellis, I O, Baglietto, L, Huntsman, D, Caldas, C, Pharoah, P D

“… Background: Tissue micro-arrays (TMAs) are increasingly used to generate data of the molecular phenotype of tumours in clinical epidemiology studies, such as …”
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Protease Activated Receptors 1 and 2 Correlate Differently with Breast Cancer Aggressiveness Depending on Tumor ER Status von Lidfeldt, Jon, Bendahl, Pär-Ola, Forsare, Carina, Malmström, Per, Fernö, Mårten, Belting, Mattias

“… Experimental models implicate protease activated receptors (PARs) as important sensors of the proteolytic tumor microenvironment during breast cancer …”
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Tissue-based Alzheimer gene expression markers–comparison of multiple machine learning approaches and investigation of redundancy in small biomarker sets von Scheubert, Lena, Luštrek, Mitja, Schmidt, Rainer, Repsilber, Dirk, Fuellen, Georg

“… Background Alzheimer’s disease has been known for more than 100 years and the underlying molecular mechanisms are not yet completely understood. The …”
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