Výsledky vyhledávání - "Tissue Array Analysis"

Cardiac Tissue Chips (CTCs) for Modeling Cardiovascular Disease Autor Rogers, Aaron J., Miller, Jessica M., Kannappan, Ramaswamy, Sethu, Palaniappan

“…Objective: Cardiovascular research and regenerative strategies have been significantly limited by the lack of relevant cell culture models that can recreate…”
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The human gut microbiome: a review of the effect of obesity and surgically induced weight loss Autor Sweeney, Timothy E, Morton, John M

“… We included studies that provided information on subjects' weight…”
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Transcriptomic analysis of probable asymptomatic and symptomatic alzheimer brains Autor Patel, Hamel, Hodges, Angela K., Curtis, Charles, Lee, Sang Hyuck, Troakes, Claire, Dobson, Richard J.B., Newhouse, Stephen J.

“…•Asymptomatic AD subjects show increased transcriptomic activity in frontal cortex…”
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A Molecular Biomarker to Diagnose Community-acquired Pneumonia on Intensive Care Unit Admission Autor Scicluna, Brendon P., Klein Klouwenberg, Peter M. C., van Vught, Lonneke A., Wiewel, Maryse A., Ong, David S. Y., Zwinderman, Aeilko H., Franitza, Marek, Toliat, Mohammad R., Nürnberg, Peter, Hoogendijk, Arie J., Horn, Janneke, Cremer, Olaf L., Schultz, Marcus J., Bonten, Marc J., van der Poll, Tom

“… Patients were designated CAP (cases) and no-CAP patients (control subjects) by post hoc assessment…”
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Clinical significance of CTNNB1 mutation and Wnt pathway activation in endometrioid endometrial carcinoma Autor Liu, Yuexin, Patel, Lalit, Mills, Gordon B, Lu, Karen H, Sood, Anil K, Ding, Li, Kucherlapati, Raju, Mardis, Elaine R, Levine, Douglas A, Shmulevich, Ilya, Broaddus, Russell R, Zhang, Wei

“…) to identify molecular fingerprints that may account for this clinical heterogeneity. Significance analysis of microarray was used to identify marker genes of each subtype that were subject to pathway analysis…”
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Synaptic gene dysregulation within hippocampal CA1 pyramidal neurons in mild cognitive impairment Autor Counts, Scott E., Alldred, Melissa J., Che, Shaoli, Ginsberg, Stephen D., Mufson, Elliott J.

“…Clinical neuropathologic studies suggest that the selective vulnerability of hippocampal CA1 pyramidal projection neurons plays a key role in the onset of…”
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Interlaboratory variability of Ki67 staining in breast cancer Autor Focke, Cornelia M., Bürger, Horst, van Diest, Paul J., Finsterbusch, Kai, Gläser, Doreen, Korsching, Eberhard, Decker, Thomas, Anders, M., Bollmann, R., Eiting, Fr, Friedrich, K., Habeck, J.-O., Haroske, G., Hinrichs, B., Behrens, A., Krause, U., Lang, U., Lorenzen, J., Minew, N., Mlynek-Kersjes, M., Nenning, H., Packeisen, J., Poche-de Vos, F., Reyher–Klein, S., Rothacker, D., Schultz, M., Sturm, U., Tawfik, M., Berghäuser, K.-H., Böcker, W., Cserni, G., Habedank, S., Lax, S., Moinfar, F., Regitnig, P., Reiner-Concin, A., Rüschoff, J., Varga, Z., Woziwodski, J.

“…Postanalytic issues of Ki67 assessment in breast cancers like counting method standardisation and interrater bias have been subject of various studies, but little is known about analytic variability…”
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Indolic uremic solutes increase tissue factor production in endothelial cells by the aryl hydrocarbon receptor pathway Autor Gondouin, Bertrand, Cerini, Claire, Dou, Laetitia, Sallée, Marion, Duval-Sabatier, Ariane, Pletinck, Anneleen, Calaf, Raymond, Lacroix, Romaric, Jourde-Chiche, Noémie, Poitevin, Stéphane, Arnaud, Laurent, Vanholder, Raymond, Brunet, Philippe, Dignat-George, Françoise, Burtey, Stéphane

“…In chronic kidney disease (CKD), uremic solutes accumulate in blood and tissues. These compounds probably contribute to the marked increase in cardiovascular…”
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An End-to-End Deep Learning Histochemical Scoring System for Breast Cancer TMA Autor Liu, Jingxin, Xu, Bolei, Zheng, Chi, Gong, Yuanhao, Garibaldi, Jon, Soria, Daniele, Green, Andew, Ellis, Ian O., Zou, Wenbin, Qiu, Guoping

“…One of the methods for stratifying different molecular classes of breast cancer is the Nottingham prognostic index plus, which uses breast cancer relevant…”
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DNA Methylation Array Identifies Golli-MBP as a Biomarker for Disease Severity in Childhood Atopic Dermatitis Autor Chen, Kuang-Den, Huang, Ying-Hsien, Guo, Mindy Ming-Huey, Chang, Ling-Sai, Chu, Chi-Hsiang, Bu, Li-Feng, Chu, Chiao-Lun, Lee, Chih-Hung, Liu, Shih-Feng, Kuo, Ho-Chang

“…). Differences in epigenome-scale methylation events in peripheral blood associated with childhood AD were screened using DNA methylation arrays of 24 patients with AD compared with 24 control subjects…”
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MicroRNA-17-5p promotes chemotherapeutic drug resistance and tumour metastasis of colorectal cancer by repressing PTEN expression Autor Fang, Lekun, Li, Haoran, Wang, Lei, Hu, Jun, Jin, Tianru, Wang, Jianping, Yang, Burton B

“… To search for potential targets of these miRNAs, tissue samples were subject to in situ hybridization and immunohistochemistry analysis…”
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Comprehensive analysis of the lncRNA-associated competing endogenous RNA network in breast cancer Autor Wang, Jing-Jing, Huang, Yue-Qing, Song, Wei, Li, Yi-Fan, Wang, Han, Wang, Wen-Jie, Huang, Min

“…Long noncoding RNAs (lncRNAs) have been confirmed to be potential prognostic markers in a variety of cancers and to interact with microRNAs (miRNAs) as…”
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Global gene expression profile of periodontal ligament cells submitted to mechanical loading: A systematic review Autor Spitz, Alice, Christovam, Ilana Oliveira, Marañón-Vásquez, Guido Artemio, Masterson, Daniele Ferreira, Adesse, Daniel, Maia, Lucianne Cople, Bolognese, Ana Maria

“…•The studies on the subject show great heterogeneity in the methods implemented.•Definitive conclusions on differentially expressed molecular pathways during orthodontic tooth movement are not yet possible…”
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Whole-exome sequencing identifies tetratricopeptide repeat domain 7A (TTC7A) mutations for combined immunodeficiency with intestinal atresias Autor Chen, Rui, Giliani, Silvia, Lanzi, Gaetana, Mias, George I., Lonardi, Silvia, Dobbs, Kerry, Manis, John, Im, Hogune, Gallagher, Jennifer E., Phanstiel, Douglas H., Euskirchen, Ghia, Lacroute, Philippe, Bettinger, Keith, Moratto, Daniele, Weinacht, Katja, Montin, Davide, Gallo, Eleonora, Mangili, Giovanna, Porta, Fulvio, Notarangelo, Lucia D., Pedretti, Stefania, Al-Herz, Waleed, Alfahdli, Wasmi, Comeau, Anne Marie, Traister, Russell S., Pai, Sung-Yun, Carella, Graziella, Facchetti, Fabio, Nadeau, Kari C., Snyder, Michael, Notarangelo, Luigi D.

“…) on 3 additional patients with CID-MIA. Through analysis and comparison of the exomic sequence of the subjects from these 5 families, we identified biallelic damaging mutations in the TTC7A gene, for a total of 7 distinct mutations…”
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MiR-146a as marker of senescence-associated pro-inflammatory status in cells involved in vascular remodelling Autor Olivieri, Fabiola, Lazzarini, Raffaella, Recchioni, Rina, Marcheselli, Fiorella, Rippo, Maria Rita, Di Nuzzo, Silvia, Albertini, Maria Cristina, Graciotti, Laura, Babini, Lucia, Mariotti, Serena, Spada, Giorgio, Abbatecola, Angela Marie, Antonicelli, Roberto, Franceschi, Claudio, Procopio, Antonio Domenico

“…In order to identify new markers of vascular cell senescence with potential in vivo implications, primary cultured endothelial cells, including human umbilical…”
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Antibodies to merkel cell polyomavirus T antigen oncoproteins reflect tumor burden in merkel cell carcinoma patients Autor Paulson, Kelly G, Carter, Joseph J, Johnson, Lisa G, Cahill, Kevin W, Iyer, Jayasri G, Schrama, David, Becker, Juergen C, Madeleine, Margaret M, Nghiem, Paul, Galloway, Denise A

“… Among 530 population control subjects, these antibodies were present in only 0.9% and were of low titer…”
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Frequent expression of napsin A in clear cell carcinoma of the endometrium: potential diagnostic utility Autor Fadare, Oluwole, Desouki, Mohamed M, Gwin, Katja, Hanley, Krisztina Z, Jarboe, Elke A, Liang, Sharon X, Quick, Charles M, Zheng, Wenxin, Parkash, Vinita, Hecht, Jonathan L

“…The histotyping of high-grade endometrial carcinomas with clear cells may be subject to significant interobserver variability, which suggests that a biomarker that can distinguish endometrial clear cell carcinoma (CCC…”
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Repair of Oxidative DNA Damage, Cell-Cycle Regulation and Neuronal Death May Influence the Clinical Manifestation of Alzheimer’s Disease Autor Silva, Aderbal R. T., Santos, Ana Cecília Feio, Farfel, Jose M., Grinberg, Lea T., Ferretti, Renata E. L., Campos, Antonio Hugo Jose Froes Marques, Cunha, Isabela Werneck, Begnami, Maria Dirlei, Rocha, Rafael M., Carraro, Dirce M., de Bragança Pereira, Carlos Alberto, Jacob-Filho, Wilson, Brentani, Helena

“…Alzheimer's disease (AD) is characterized by progressive cognitive decline associated with a featured neuropathology (neuritic plaques and neurofibrillary…”
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Overexpression of the MRE11-RAD50-NBS1 (MRN) complex in rectal cancer correlates with poor response to neoadjuvant radiotherapy and prognosis Autor Ho, Vincent, Chung, Liping, Singh, Amandeep, Lea, Vivienne, Abubakar, Askar, Lim, Stephanie H., Ng, Weng, Lee, Mark, de Souza, Paul, Shin, Joo-Shik, Lee, Cheok Soon

“…, RAD50 and NBS1 proteins in the pathogenesis of various cancers is the subject of investigation. This study was aimed at assessing the three-protein panel of MRN…”
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Cell-Specific Detection of miR-375 Downregulation for Predicting the Prognosis of Esophageal Squamous Cell Carcinoma by miRNA In Situ Hybridization Autor Li, Jiangchao, Li, Xiaodong, Li, Yan, Yang, Hong, Wang, Lijing, Qin, Yanru, Liu, Haibo, Fu, Li, Guan, Xin-Yuan

“…MicroRNAs (miRNAs) play important roles in the regulation of genes associated with cancer development and progression. By the more deeply characterization of…”
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