Suchergebnisse - "Su, Dunhao"

Assembly of alternative prothrombinase by extracellular histones initiates and disseminates intravascular coagulation von Abrams, Simon T, Su, Dunhao, Sahraoui, Yasmina, Lin, Ziqi, Cheng, Zhenxing, Nesbitt, Kate, Alhamdi, Yasir, Harrasser, Micaela, Du, Min, Foley, Jonathan H, Lillicrap, David, Wang, Guozheng, Toh, Cheng-Hock

“… Thrombin generation is pivotal to both physiological blood clot formation and pathological development of disseminated intravascular coagulation (DIC). In …”
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The heparin-binding proteome in normal pancreas and murine experimental acute pancreatitis von Nunes, Quentin M., Su, Dunhao, Brownridge, Philip J., Simpson, Deborah M., Sun, Changye, Li, Yong, Bui, Thao P., Zhang, Xiaoying, Huang, Wei, Rigden, Daniel J., Beynon, Robert J., Sutton, Robert, Fernig, David G.

“… Acute pancreatitis (AP) is acute inflammation of the pancreas, mainly caused by gallstones and alcohol, driven by changes in communication between cells …”
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Circulating Histone Concentrations Differentially Affect the Predominance of Left or Right Ventricular Dysfunction in Critical Illness von Alhamdi, Yasir, Zi, Min, Abrams, Simon T, Liu, Tingting, Su, Dunhao, Welters, Ingeborg, Dutt, Tina, Cartwright, Elizabeth J, Wang, Guozheng, Toh, Cheng-Hock

“… Cardiac complications are common in critical illness and associated with grave consequences. In this setting, elevated circulating histone levels have been …”
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Heparin Inhibits Cellular Invasion by SARS-CoV-2: Structural Dependence of the Interaction of the Spike S1 Receptor-Binding Domain with Heparin von Mycroft-West, Courtney J., Su, Dunhao, Pagani, Isabel, Rudd, Timothy R., Elli, Stefano, Gandhi, Neha S., Guimond, Scott E., Miller, Gavin J., Meneghetti, Maria C. Z., Nader, Helena B., Li, Yong, Nunes, Quentin M., Procter, Patricia, Mancini, Nicasio, Clementi, Massimo, Bisio, Antonella, Forsyth, Nicholas R., Ferro, Vito, Turnbull, Jeremy E., Guerrini, Marco, Fernig, David G., Vicenzi, Elisa, Yates, Edwin A., Lima, Marcelo A., Skidmore, Mark A.

“… Abstract The dependence of development and homeostasis in animals on the interaction of hundreds of extracellular regulatory proteins with the peri- and …”
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Circulating Histones Are Major Mediators of Cardiac Injury in Patients With Sepsis von Alhamdi, Yasir, Abrams, Simon T, Cheng, Zhenxing, Jing, Shengjie, Su, Dunhao, Liu, Zhiyong, Lane, Steven, Welters, Ingeborg, Wang, Guozheng, Toh, Cheng-Hock

“… To investigate the impact of circulating histones on cardiac injury and dysfunction in a murine model and patients with sepsis. Prospective, observational …”
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Extracellular histones inhibit complement activation through interactions with complement component C4b von Qaddoori, Yasir, Abrams, Simon T., Su, Dunhao, Liu, Tingting, Alhamdi, Yasir, Wang, Guozheng, Toh, Cheng-Hock

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Analysis of protein-heparin interactions using a portable SPR instrument von Su, Dunhao, Li, Yong, Yates, Edwin A., Skidmore, Mark A., Lima, Marcelo A., Fernig, David G.

“… Optical biosensors such as those based on surface plasmon resonance (SPR) are a key analytical tool for understanding biomolecular interactions and function as …”
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The 2019 coronavirus (SARS-CoV-2) surface protein (Spike) S1 Receptor Binding Domain undergoes conformational change upon heparin binding von Mycroft-West, Courtney J, Su, Dunhao, Elli, Stefano, Li, Yong, Guimond, Scott E, Miller, Gavin J, Turnbull, Jeremy E, Yates, Edwin A, Guerrini, Marco, Fernig, David G, Andrade De Lima, Marcelo, Skidmore, Mark A

“… Many pathogens take advantage of the dependence of the host on the interaction of hundreds of extracellular proteins with the glycosaminoglycans heparan …”
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Assembly of alternative prothrombinase by extracellular histones initiate and disseminate intravascular coagulation von Abrams, Simon Timothy, Su, Dunhao, Sahraoui, Yasmina, Lin, Ziqi, Cheng, Zhenxing, Nesbitt, Kate, Alhamdi, Yasir, Harrasser, Micaela, Du, Min, Foley, Jonathan, Lillicrap, David, Wang, Guozheng, Toh, Cheng-Hock

“… Thrombin generation is pivotal to both physiological blood clot formation and pathological development of disseminated intravascular coagulation (DIC). In …”
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Production, characterisation and application of humanised anti-histone antibodies in critical illness von Su, Dunhao

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Concentration- and time-dependence of phosphorylation events stimulated by fibroblast growth factor-4 (FGF-4) in Rama 27 fibroblasts von Alsadun, Marim M., Su, Dunhao, Yates, Edwin A., Fernig, David G.

“… Gradients of FGFs are an essential feature of many developmental processes. Thus, FGF2 stimulates different responses at high and low concentrations, while …”
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Heparin inhibits cellular invasion by SARS-CoV-2: structural dependence of the interaction of the surface protein (spike) S1 receptor binding domain with heparin von Mycroft-West, Courtney J., Su, Dunhao, Pagani, Isabel, Rudd, Timothy R., Elli, Stefano, Guimond, Scott E., Miller, Gavin, Meneghetti, Maria C. Z., Nader, Helena B., Li, Yong, Nunes, Quentin M., Procter, Patricia, Mancini, Nicasio, Clementi, Massimo, Bisio, Antonella, Forsyth, Nicholas R., Turnbull, Jeremy E., Guerrini, Marco, Fernig, David G., Vicenzi, Elisa, Yates, Edwin A., Lima, Marcelo A., Skidmore, Mark A.

“… The dependence of the host on the interaction of hundreds of extracellular proteins with the cell surface glycosaminoglycan heparan sulphate (HS) for the …”
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Glycosaminoglycans induce conformational change in the SARS-CoV-2 Spike S1 Receptor Binding Domain von Mycroft-West, Courtney J., Su, Dunhao, Li, Yong, Guimond, Scott E., Rudd, Timothy R., Elli, Stefano, Miller, Gavin, Nunes, Quentin M., Procter, Patricia, Bisio, Antonella, Forsyth, Nicholas R., Turnbull, Jeremy E., Guerrini, Marco, Fernig, David G., Yates, Edwin A., Lima, Marcelo A., Skidmore, Mark A.

“… The glycosaminoglycan (GAG) class of polysaccharides are utilised by a plethora of microbial pathogens as receptors for adherence and invasion. The GAG heparin …”
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SARS-CoV-2 Spike S1 Receptor Binding Domain undergoes Conformational Change upon Interaction with Low Molecular Weight Heparins von Mycroft-West, Courtney J., Su, Dunhao, Li, Yong, Guimond, Scott E., Rudd, Timothy R., Elli, Stefano, Miller, Gavin, Nunes, Quentin M., Procter, Patricia, Bisio, Antonella, Forsyth, Nicholas R., Turnbull, Jeremy E., Guerrini, Marco, Fernig, David G., Yates, Edwin A., Lima, Marcelo A., Skidmore, Mark A.

“… The dependence of the host on the interaction of hundreds of extracellular proteins with the cell surface glycosaminoglycan heparan sulphate (HS) for the …”
Volltext

The heparin-binding proteome in normal pancreas and murine experimental acute pancreatitis von Nunes, Quentin M, Su, Dunhao, Brownridge, Philip J, Simpson, Deborah M, Sun, Changye, Li, Yong, Phuong Thao P Bui, Zhang, Xiaoying, Huang, Wei, Rigden, Daniel J, Beynon, Robert J, Sutton, Robert, Fernig, David G

“… Acute pancreatitis (AP) is acute inflammation of the pancreas, mainly caused by gallstones and alcohol, driven by changes in communication between cells …”
Volltext