Výsledky vyhľadávania - "Spencer, Andrew"

Human‐Recombinant‐Elastin‐Based Bioinks for 3D Bioprinting of Vascularized Soft Tissues Autor Lee, Sohyung, Sani, Ehsan Shirzaei, Spencer, Andrew R., Guan, Yvonne, Weiss, Anthony S., Annabi, Nasim

“…Bioprinting has emerged as an advanced method for fabricating complex 3D tissues. Despite the tremendous potential of 3D bioprinting, there are several…”
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Nobility and Kingship in Medieval England: The Earls and Edward I, 1272–1307 Autor Spencer, Andrew M.

“…Nobility and Kingship in Medieval England is a major new account of the relationship between Edward I and his earls, and of the role of the English nobility in…”
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Bioprinting of a Cell-Laden Conductive Hydrogel Composite Autor Spencer, Andrew R, Shirzaei Sani, Ehsan, Soucy, Jonathan R, Corbet, Carolyn C, Primbetova, Asel, Koppes, Ryan A, Annabi, Nasim

“…Bioprinting has gained significant attention for creating biomimetic tissue constructs with potential to be used in biomedical applications such as drug…”
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Transition metal-free cross-dehydrogenative arylation of unactivated benzylic C-H bonds Autor Spencer, Andrew R. A., Grainger, Rachel, Panigrahi, Adyasha, Lepper, Thomas J., Bentkowska, Katarzyna, Larrosa, Igor

“…The cross-dehydrogenative arylation of benzylic C-H bonds with arenes provides straightforward access to synthetically useful 1,1-diarylmethanes, from readily…”
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Daratumumab, Bortezomib, Lenalidomide, and Dexamethasone for Multiple Myeloma Autor Sonneveld, Pieter, Dimopoulos, Meletios A., Boccadoro, Mario, Quach, Hang, Ho, P. Joy, Beksac, Meral, Hulin, Cyrille, Antonioli, Elisabetta, Leleu, Xavier, Mangiacavalli, Silvia, Perrot, Aurore, Cavo, Michele, Belotti, Angelo, Broijl, Annemiek, Gay, Francesca, Mina, Roberto, Nijhof, Inger S., van de Donk, Niels W.C.J., Katodritou, Eirini, Schjesvold, Fredrik, Sureda Balari, Anna, Rosiñol, Laura, Delforge, Michel, Roeloffzen, Wilfried, Silzle, Tobias, Vangsted, Annette, Einsele, Hermann, Spencer, Andrew, Hajek, Roman, Jurczyszyn, Artur, Lonergan, Sarah, Ahmadi, Tahamtan, Liu, Yanfang, Wang, Jianping, Vieyra, Diego, van Brummelen, Emilie M.J., Vanquickelberghe, Veronique, Sitthi-Amorn, Anna, de Boer, Carla J., Carson, Robin, Rodriguez-Otero, Paula, Bladé, Joan, Moreau, Philippe

“…The addition of subcutaneous daratumumab to bortezomib, lenalidomide, and dexamethasone therapy and to lenalidomide maintenance therapy had a significant…”
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meta -C–H arylation of fluoroarenes via traceless directing group relay strategy Autor Font, Marc, Spencer, Andrew R. A., Larrosa, Igor

“…While several methods for the ortho selective arylation of fluoroarenes, meta -functionalisation has never been achieved. We report a new methodology, based on…”
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Cilta-cel or Standard Care in Lenalidomide-Refractory Multiple Myeloma Autor San-Miguel, Jesús, Dhakal, Binod, Yong, Kwee, Spencer, Andrew, Anguille, Sébastien, Mateos, María-Victoria, Fernández de Larrea, Carlos, Martínez-López, Joaquín, Moreau, Philippe, Touzeau, Cyrille, Leleu, Xavier, Avivi, Irit, Cavo, Michele, Ishida, Tadao, Kim, Seok Jin, Roeloffzen, Wilfried, van de Donk, Niels W.C.J., Dytfeld, Dominik, Sidana, Surbhi, Costa, Luciano J., Oriol, Albert, Popat, Rakesh, Khan, Abdullah M., Cohen, Yaël C., Ho, P. Joy, Griffin, James, Lendvai, Nikoletta, Lonardi, Carolina, Slaughter, Ana, Schecter, Jordan M., Jackson, Carolyn C., Connors, Kaitlyn, Li, Katherine, Zudaire, Enrique, Chen, Diana, Gilbert, Jane, Yeh, Tzu-min, Nagle, Sarah, Florendo, Erika, Pacaud, Lida, Patel, Nitin, Harrison, Simon J., Einsele, Hermann

“…Patients with lenalidomide-refractory disease who received ciltacabtagene autoleucel had significantly longer progression-free survival than those who received…”
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Targeting MCL-1 in hematologic malignancies: Rationale and progress Autor Wei, Andrew H., Roberts, Andrew W., Spencer, Andrew, Rosenberg, Aaron Seth, Siegel, David, Walter, Roland B., Caenepeel, Sean, Hughes, Paul, McIver, Zach, Mezzi, Khalid, Morrow, Phuong Khanh, Stein, Anthony

“…Myeloid cell leukemia sequence 1 (MCL-1) is an antiapoptotic protein that plays a key role in promoting cell survival in multiple myeloma (MM), acute myeloid…”
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International Myeloma Working Group consensus criteria for response and minimal residual disease assessment in multiple myeloma Autor Kumar, Shaji, Paiva, Bruno, Anderson, Kenneth C, Durie, Brian, Landgren, Ola, Moreau, Philippe, Munshi, Nikhil, Lonial, Sagar, Bladé, Joan, Mateos, Maria-Victoria, Dimopoulos, Meletios, Kastritis, Efstathios, Boccadoro, Mario, Orlowski, Robert, Goldschmidt, Hartmut, Spencer, Andrew, Hou, Jian, Chng, Wee Joo, Usmani, Saad Z, Zamagni, Elena, Shimizu, Kazuyuki, Jagannath, Sundar, Johnsen, Hans E, Terpos, Evangelos, Reiman, Anthony, Kyle, Robert A, Sonneveld, Pieter, Richardson, Paul G, McCarthy, Philip, Ludwig, Heinz, Chen, Wenming, Cavo, Michele, Harousseau, Jean-Luc, Lentzsch, Suzanne, Hillengass, Jens, Palumbo, Antonio, Orfao, Alberto, Rajkumar, S Vincent, Miguel, Jesus San, Avet-Loiseau, Herve

“…Treatment of multiple myeloma has substantially changed over the past decade with the introduction of several classes of new effective drugs that have greatly…”
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Revised International Staging System for Multiple Myeloma: A Report From International Myeloma Working Group Autor Palumbo, Antonio, Avet-Loiseau, Hervé, Oliva, Stefania, Lokhorst, Henk M, Goldschmidt, Hartmut, Rosinol, Laura, Richardson, Paul, Caltagirone, Simona, Lahuerta, Juan José, Facon, Thierry, Bringhen, Sara, Gay, Francesca, Attal, Michel, Passera, Roberto, Spencer, Andrew, Offidani, Massimo, Kumar, Shaji, Musto, Pellegrino, Lonial, Sagar, Petrucci, Maria T, Orlowski, Robert Z, Zamagni, Elena, Morgan, Gareth, Dimopoulos, Meletios A, Durie, Brian G M, Anderson, Kenneth C, Sonneveld, Pieter, San Miguel, Jésus, Cavo, Michele, Rajkumar, S Vincent, Moreau, Philippe

“…The clinical outcome of multiple myeloma (MM) is heterogeneous. A simple and reliable tool is needed to stratify patients with MM. We combined the…”
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meta-Selective olefination of fluoroarenes with alkynes using CO2 as a traceless directing group Autor Spencer, Andrew R. A., Korde, Rishi, Font, Marc, Larrosa, Igor

“…Over the last few decades C-H olefination has received significant interest, due to the importance and usefulness of aryl olefins both as synthetic targets and…”
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Dysregulated Class I histone deacetylases are indicators of poor prognosis in multiple myeloma Autor Mithraprabhu, Sridurga, Kalff, Anna, Chow, Annie, Khong, Tiffany, Spencer, Andrew

“…Histone deacetylases (HDAC) control gene expression through their ability to acetylate proteins, thereby influencing a diverse range of cellular functions…”
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Elotuzumab Therapy for Relapsed or Refractory Multiple Myeloma Autor Lonial, Sagar, Dimopoulos, Meletios, Palumbo, Antonio, White, Darrell, Grosicki, Sebastian, Spicka, Ivan, Walter-Croneck, Adam, Moreau, Philippe, Mateos, Maria-Victoria, Magen, Hila, Belch, Andrew, Reece, Donna, Beksac, Meral, Spencer, Andrew, Oakervee, Heather, Orlowski, Robert Z, Taniwaki, Masafumi, Röllig, Christoph, Einsele, Hermann, Wu, Ka Lung, Singhal, Anil, San-Miguel, Jesus, Matsumoto, Morio, Katz, Jessica, Bleickardt, Eric, Poulart, Valerie, Anderson, Kenneth C, Richardson, Paul

“…The addition of elotuzumab (a monoclonal antibody against SLAMF7) to lenalidomide plus dexamethasone produced a significant increase in progression-free…”
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Electroconductive Gelatin Methacryloyl-PEDOT:PSS Composite Hydrogels: Design, Synthesis, and Properties Autor Spencer, Andrew R, Primbetova, Asel, Koppes, Abigail N, Koppes, Ryan A, Fenniri, Hicham, Annabi, Nasim

“…Electroconductive hydrogels are used in a wide range of biomedical applications, including electrodes for patient monitoring and electrotherapy, or as…”
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Linsitinib, an IGF-1R inhibitor, attenuates disease development and progression in a model of thyroid eye disease Autor Gulbins, Anne, Horstmann, Mareike, Daser, Anke, Flögel, Ulrich, Oeverhaus, Michael, Bechrakis, Nikolaos E., Banga, J. Paul, Keitsch, Simone, Wilker, Barbara, Krause, Gerd, Hammer, Gary D., Spencer, Andrew G., Zeidan, Ryan, Eckstein, Anja, Philipp, Svenja, Görtz, Gina-Eva

“…Graves' disease (GD) is an autoimmune disorder caused by autoantibodies against the thyroid stimulating hormone receptor (TSHR) leading to overstimulation of…”
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Biomimetic cardiovascular platforms for in vitro disease modeling and therapeutic validation Autor Portillo-Lara, Roberto, Spencer, Andrew R., Walker, Brian W., Shirzaei Sani, Ehsan, Annabi, Nasim

“…Bioengineered tissues have become increasingly more sophisticated owing to recent advancements in the fields of biomaterials, microfabrication, microfluidics,…”
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Water fluoridation as a population strategy for reducing oral health inequalities: high-dimensional effect heterogeneity analysis using machine learning Autor Matsuyama, Yusuke, Ha, Diep H, Kiuchi, Sakura, Spencer, Andrew J, Aida, Jun, Do, Loc G

“…Dental caries is the most prevalent disease worldwide, associated with substantial health inequalities. Water fluoridation is a population strategy shown to…”
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Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition Autor Hogg, Simon J, Motorna, Olga, Cluse, Leonie A, Johanson, Timothy M, Coughlan, Hannah D, Raviram, Ramya, Myers, Robert M, Costacurta, Matteo, Todorovski, Izabela, Pijpers, Lizzy, Bjelosevic, Stefan, Williams, Tobias, Huskins, Shannon N, Kearney, Conor J, Devlin, Jennifer R, Fan, Zheng, Jabbari, Jafar S, Martin, Ben P, Fareh, Mohamed, Kelly, Madison J, Dupéré-Richer, Daphné, Sandow, Jarrod J, Feran, Breon, Knight, Deborah, Khong, Tiffany, Spencer, Andrew, Harrison, Simon J, Gregory, Gareth, Wickramasinghe, Vihandha O, Webb, Andrew I, Taberlay, Phillippa C, Bromberg, Kenneth D, Lai, Albert, Papenfuss, Anthony T, Smyth, Gordon K, Allan, Rhys S, Licht, Jonathan D, Landau, Dan A, Abdel-Wahab, Omar, Shortt, Jake, Vervoort, Stephin J, Johnstone, Ricky W

“…To separate causal effects of histone acetylation on chromatin accessibility and transcriptional output, we used integrated epigenomic and transcriptomic…”
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Randomized, double-blind study of denosumab versus zoledronic acid in the treatment of bone metastases in patients with advanced cancer (excluding breast and prostate cancer) or multiple myeloma Autor Henry, David H, Costa, Luis, Goldwasser, Francois, Hirsh, Vera, Hungria, Vania, Prausova, Jana, Scagliotti, Giorgio Vittorio, Sleeboom, Harm, Spencer, Andrew, Vadhan-Raj, Saroj, von Moos, Roger, Willenbacher, Wolfgang, Woll, Penella J, Wang, Jianming, Jiang, Qi, Jun, Susie, Dansey, Roger, Yeh, Howard

“…This study compared denosumab, a fully human monoclonal anti-receptor activator of nuclear factor kappa-B ligand antibody, with zoledronic acid (ZA) for…”
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Prognostic value of minimal residual disease negativity in myeloma: combined analysis of POLLUX, CASTOR, ALCYONE, and MAIA Autor Cavo, Michele, San-Miguel, Jesus, Usmani, Saad Z, Weisel, Katja, Dimopoulos, Meletios A, Avet-Loiseau, Hervé, Paiva, Bruno, Bahlis, Nizar J, Plesner, Torben, Hungria, Vania, Moreau, Philippe, Mateos, Maria-Victoria, Perrot, Aurore, Iida, Shinsuke, Facon, Thierry, Kumar, Shaji, van de Donk, Niels W C J, Sonneveld, Pieter, Spencer, Andrew, Krevvata, Maria, Heuck, Christoph, Wang, Jianping, Ukropec, Jon, Kobos, Rachel, Sun, Steven, Qi, Mia, Munshi, Nikhil

“…We explored minimal residual disease (MRD) in relapsed/refractory multiple myeloma (RRMM) and transplant-ineligible (TIE) newly diagnosed multiple myeloma…”
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