Suchergebnisse - "Sheikh, Imran S."

Compensatory adaptation of parallel motor pathways promotes skilled forelimb recovery after spinal cord injury von Sheikh, Imran S., Keefe, Kathleen M., Sterling, Noelle A., Junker, Ian P., Li, Chen, Chen, Jie, Xu, Xiao-Ming, Kirby, Lynn G., Smith, George M.

“… Skilled forelimb patterning is regulated by the corticospinal tract (CST) with support from brainstem regions. When the CST is lesioned, there is a loss of …”
Volltext

Retrogradely Transportable Lentivirus Tracers for Mapping Spinal Cord Locomotor Circuits von Sheikh, Imran S., Keefe, Kathleen M., Sterling, Noelle A., Junker, Ian P., Eneanya, Chidubem I., Liu, Yingpeng, Tang, Xiao-Qing, Smith, George M.

“… Retrograde tracing is a key facet of neuroanatomical studies involving long distance projection neurons. Previous groups have utilized a variety of tools …”
Volltext

Targeting Neurotrophins to Specific Populations of Neurons: NGF, BDNF, and NT-3 and Their Relevance for Treatment of Spinal Cord Injury von Keefe, Kathleen, Sheikh, Imran, Smith, George

“… Neurotrophins are a family of proteins that regulate neuronal survival, synaptic function, and neurotransmitter release, and elicit the plasticity and growth …”
Volltext

Direct Injection of a Lentiviral Vector Highlights Multiple Motor Pathways in the Rat Spinal Cord von Keefe, Kathleen M., Junker, Ian P., Sheikh, Imran S., Campion, Thomas J., Smith, George M.

“… Introducing proteins of interest into cells in the nervous system is challenging due to innate biological barriers that limit access to most molecules …”
Volltext

Viral expression of constitutively active AKT3 induces CST axonal sprouting and regeneration, but also promotes seizures von Campion, Thomas J., Sheikh, Imran S., Smit, Rupert D., Iffland, Philip H., Chen, Jie, Junker, Ian P., Krynska, Barbara, Crino, Peter B., Smith, George M.

“… Increasing the intrinsic growth potential of neurons after injury has repeatedly been shown to promote some level of axonal regeneration in rodent models. One …”
Volltext

Withdrawal from chronic administration of cocaine decreases delta opioid receptor signaling and increases anxiety- and depression-like behaviors in the rat von Perrine, Shane A., Sheikh, Imran S., Nwaneshiudu, Chinwe A., Schroeder, Joseph A., Unterwald, Ellen M.

“… Chronic administration of cocaine has been shown to attenuate the functional capacity of delta opioid receptors to inhibit adenylyl cyclase activity. Abuse and …”
Volltext

Novel C-1 substituted cocaine analogs unlike cocaine or benztropine von Reith, Maarten E A, Ali, Solav, Hashim, Audrey, Sheikh, Imran S, Theddu, Naresh, Gaddiraju, Narendra V, Mehrotra, Suneet, Schmitt, Kyle C, Murray, Thomas F, Sershen, Henry, Unterwald, Ellen M, Davis, Franklin A

“… Despite a wealth of information on cocaine-like compounds, there is no information on cocaine analogs with substitutions at C-1. Here, we report on …”
Weitere Angaben

Direct Injection of a Lentiviral Vector Highlights Multiple Motor Pathways in the Rat Spinal Cord von Keefe, Kathleen M., Junker, Ian P., Sheikh, Imran S., Campion, Thomas J., Smith, George M.

Volltext

Ketamine reverses stress-induced depression-like behavior and increased GABA levels in the anterior cingulate: An 11.7T 1H-MRS study in rats von Perrine, Shane A., Ghoddoussi, Farhad, Michaels, Mark S., Sheikh, Imran S., McKelvey, George, Galloway, Matthew P.

“… Gamma-aminobutyric acid (GABA) is the major inhibitory amino acid neurotransmitter in the brain and is primarily responsible for modulating excitatory tone …”
Volltext

Ketamine reverses stress-induced depression-like behavior and increased GABA levels in the anterior cingulate: An 11.7 T 1H-MRS study in rats von PERRINE, Shane A, GHODDOUSSI, Farhad, MICHAELS, Mark S, SHEIKH, Imran S, MCKELVEY, George, GALLOWAY, Matthew P

“… Gamma-aminobutyric acid (GABA) is the major inhibitory amino acid neurotransmitter in the brain and is primarily responsible for modulating excitatory tone …”
Volltext

Ketamine reverses stress-induced depression-like behavior and increased GABA levels in the anterior cingulate: An 11.7 T super(1)H-MRS study in rats von Perrine, Shane A, Ghoddoussi, Farhad, Michaels, Mark S, Sheikh, Imran S, McKelvey, George, Galloway, Matthew P

“… Gamma-aminobutyric acid (GABA) is the major inhibitory amino acid neurotransmitter in the brain and is primarily responsible for modulating excitatory tone …”
Volltext

The Role of C3-C4 Propriospinal Interneurons on Reaching and Grasping Behaviors Pre- and Post-cervical Spinal Cord Injury von Sheikh, Imran S

“… Greater than 50% of all spinal cord injuries (SCIs) in humans occur at the cervical level and the biggest desire of quadriplegic patients is recovery of hand …”
Volltext