Search Results - "Shah, Ronak"

Bradycardia in severely dehydrated cholera patient: A case report by Shah, Ronak

“…Rationale: Cholera is an acute diarrheal disease caused by the ingestion of food or water contaminated by Vibrio cholerae. It threatens global health and…”
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Genomic and transcriptomic hallmarks of poorly differentiated and anaplastic thyroid cancers by Landa, Iñigo, Ibrahimpasic, Tihana, Boucai, Laura, Sinha, Rileen, Knauf, Jeffrey A., Shah, Ronak H., Dogan, Snjezana, Ricarte-Filho, Julio C., Krishnamoorthy, Gnana P., Xu, Bin, Schultz, Nikolaus, Berger, Michael F., Sander, Chris, Taylor, Barry S., Ghossein, Ronald, Ganly, Ian, Fagin, James A.

“…Poorly differentiated thyroid cancer (PDTC) and anaplastic thyroid cancer (ATC) are rare and frequently lethal tumors that so far have not been subjected to…”
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Antitumour activity of neratinib in patients with HER2-mutant advanced biliary tract cancers by Harding, James J., Piha-Paul, Sarina A., Shah, Ronak H., Murphy, Jessica J., Cleary, James M., Shapiro, Geoffrey I., Quinn, David I., Braña, Irene, Moreno, Victor, Borad, Mitesh, Loi, Sherene, Spanggaard, Iben, Park, Haeseong, Ford, James M., Arnedos, Mónica, Stemmer, Salomon M., de la Fouchardiere, Christelle, Fountzilas, Christos, Zhang, Jie, DiPrimeo, Daniel, Savin, Casey, Duygu Selcuklu, S., Berger, Michael F., Eli, Lisa D., Meric-Bernstam, Funda, Jhaveri, Komal, Solit, David B., Abou-Alfa, Ghassan K.

“…HER2 mutations are infrequent genomic events in biliary tract cancers (BTCs). Neratinib, an irreversible, pan-HER, oral tyrosine kinase inhibitor, interferes…”
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Evaluating Cancer of the Central Nervous System Through Next-Generation Sequencing of Cerebrospinal Fluid by Pentsova, Elena I, Shah, Ronak H, Tang, Jiabin, Boire, Adrienne, You, Daoqi, Briggs, Samuel, Omuro, Antonio, Lin, Xuling, Fleisher, Martin, Grommes, Christian, Panageas, Katherine S, Meng, Fanli, Selcuklu, S Duygu, Ogilvie, Shahiba, Distefano, Natalie, Shagabayeva, Larisa, Rosenblum, Marc, DeAngelis, Lisa M, Viale, Agnes, Mellinghoff, Ingo K, Berger, Michael F

“…Cancer spread to the central nervous system (CNS) often is diagnosed late and is unresponsive to therapy. Mechanisms of tumor dissemination and evolution…”
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Staphylococcus aureus bacteraemia for the general physician: A narrative review of a metastatic infection with malignant complications by Shah, Ronak J., Baltas, Ioannis

“…•Staphylococcus aureus bacteraemia (SAB) carries a significant case fatality ratio (20–25%) in the UK setting.•Early identification of the source of infection…”
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Injectable controlled release depots for large molecules by Schwendeman, Steven P., Shah, Ronak B., Bailey, Brittany A., Schwendeman, Anna S.

“…Biodegradable, injectable depot formulations for long-term controlled drug release have improved therapy for a number of drug molecules and led to over a dozen…”
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Tracking tumour evolution in glioma through liquid biopsies of cerebrospinal fluid by Miller, Alexandra M., Shah, Ronak H., Pentsova, Elena I., Pourmaleki, Maryam, Briggs, Samuel, Distefano, Natalie, Zheng, Youyun, Skakodub, Anna, Mehta, Smrutiben A., Campos, Carl, Hsieh, Wan-Ying, Selcuklu, S. Duygu, Ling, Lilan, Meng, Fanli, Jing, Xiaohong, Samoila, Aliaksandra, Bale, Tejus A., Tsui, Dana W. Y., Grommes, Christian, Viale, Agnes, Souweidane, Mark M., Tabar, Viviane, Brennan, Cameron W., Reiner, Anne S., Rosenblum, Marc, Panageas, Katherine S., DeAngelis, Lisa M., Young, Robert J., Berger, Michael F., Mellinghoff, Ingo K.

“…Diffuse gliomas are the most common malignant brain tumours in adults and include glioblastomas and World Health Organization (WHO) grade II and grade III…”
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Sulforaphane enhances the anticancer activity of taxanes against triple negative breast cancer by killing cancer stem cells by Burnett, Joseph P., Lim, Gi, Li, Yanyan, Shah, Ronak B., Lim, Rebekah, Paholak, Hayley J., McDermott, Sean P., Sun, Lichao, Tsume, Yasuhiro, Bai, Shuhua, Wicha, Max S., Sun, Duxin, Zhang, Tao

“…Triple negative breast cancer (TNBC) typically exhibits rapid progression, high mortality and faster relapse rates relative to other breast cancer subtypes. In…”
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Comparative sequencing analysis reveals high genomic concordance between matched primary and metastatic colorectal cancer lesions by Brannon, A Rose, Vakiani, Efsevia, Sylvester, Brooke E, Scott, Sasinya N, McDermott, Gregory, Shah, Ronak H, Kania, Krishan, Viale, Agnes, Oschwald, Dayna M, Vacic, Vladimir, Emde, Anne-Katrin, Cercek, Andrea, Yaeger, Rona, Kemeny, Nancy E, Saltz, Leonard B, Shia, Jinru, D’Angelica, Michael I, Weiser, Martin R, Solit, David B, Berger, Michael F

“…Background Colorectal cancer is the second leading cause of cancer death in the United States, with over 50,000 deaths estimated in 2014. Molecular profiling…”
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Memorial Sloan Kettering-Integrated Mutation Profiling of Actionable Cancer Targets (MSK-IMPACT): A Hybridization Capture-Based Next-Generation Sequencing Clinical Assay for Solid Tumor Molecular Oncology by Cheng, Donavan T, Mitchell, Talia N, Zehir, Ahmet, Shah, Ronak H, Benayed, Ryma, Syed, Aijazuddin, Chandramohan, Raghu, Liu, Zhen Yu, Won, Helen H, Scott, Sasinya N, Brannon, A Rose, O'Reilly, Catherine, Sadowska, Justyna, Casanova, Jacklyn, Yannes, Angela, Hechtman, Jaclyn F, Yao, Jinjuan, Song, Wei, Ross, Dara S, Oultache, Alifya, Dogan, Snjezana, Borsu, Laetitia, Hameed, Meera, Nafa, Khedoudja, Arcila, Maria E, Ladanyi, Marc, Berger, Michael F

“…The identification of specific genetic alterations as key oncogenic drivers and the development of targeted therapies are together transforming clinical…”
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Convergent loss of PTEN leads to clinical resistance to a PI(3)Kα inhibitor by Juric, Dejan, Castel, Pau, Griffith, Malachi, Griffith, Obi L., Won, Helen H., Ellis, Haley, Ebbesen, Saya H., Ainscough, Benjamin J., Ramu, Avinash, Iyer, Gopa, Shah, Ronak H., Huynh, Tiffany, Mino-Kenudson, Mari, Sgroi, Dennis, Isakoff, Steven, Thabet, Ashraf, Elamine, Leila, Solit, David B., Lowe, Scott W., Quadt, Cornelia, Peters, Malte, Derti, Adnan, Schegel, Robert, Huang, Alan, Mardis, Elaine R., Berger, Michael F., Baselga, José, Scaltriti, Maurizio

“…A study of genome evolution in a metastatic breast cancer bearing an activating PIK3CA mutation, following treatment with the PI(3)Kα inhibitor BYL719, shows…”
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Recurrent SMARCA4 mutations in small cell carcinoma of the ovary by Jelinic, Petar, Mueller, Jennifer J, Olvera, Narciso, Dao, Fanny, Scott, Sasinya N, Shah, Ronak, Gao, JianJiong, Schultz, Nikolaus, Gonen, Mithat, Soslow, Robert A, Berger, Michael F, Levine, Douglas A

“…Douglas Levine and colleagues identify recurrent inactivating mutations in the SWI/SNF complex member SMARCA4 in 12 of 12 samples of small cell carcinoma of…”
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Genomic Characterization of Upper Tract Urothelial Carcinoma by Sfakianos, John P., Cha, Eugene K., Iyer, Gopa, Scott, Sasinya N., Zabor, Emily C., Shah, Ronak H., Ren, Qinghu, Bagrodia, Aditya, Kim, Philip H., Hakimi, A. Ari, Ostrovnaya, Irina, Ramirez, Ricardo, Hanrahan, Aphrothiti J., Desai, Neil B., Sun, Arony, Pinciroli, Patrizia, Rosenberg, Jonathan E., Dalbagni, Guido, Schultz, Nikolaus, Bajorin, Dean F., Reuter, Victor E., Berger, Michael F., Bochner, Bernard H., Al-Ahmadie, Hikmat A., Solit, David B., Coleman, Jonathan A.

“…Despite a similar histologic appearance, upper tract urothelial carcinoma (UTUC) and urothelial carcinoma of the bladder (UCB) tumors have distinct…”
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Alternative transcription initiation leads to expression of a novel ALK isoform in cancer by Wiesner, Thomas, Lee, William, Obenauf, Anna C., Ran, Leili, Murali, Rajmohan, Zhang, Qi Fan, Wong, Elissa W. P., Hu, Wenhuo, Scott, Sasinya N., Shah, Ronak H., Landa, Iñigo, Button, Julia, Lailler, Nathalie, Sboner, Andrea, Gao, Dong, Murphy, Devan A., Cao, Zhen, Shukla, Shipra, Hollmann, Travis J., Wang, Lu, Borsu, Laetitia, Merghoub, Taha, Schwartz, Gary K., Postow, Michael A., Ariyan, Charlotte E., Fagin, James A., Zheng, Deyou, Ladanyi, Marc, Busam, Klaus J., Berger, Michael F., Chen, Yu, Chi, Ping

“…A novel ALK transcript expressed in a subset of human cancers, arising from a de novo alternative transcription initiation site within the ALK gene, is…”
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Ultrasensitive plasma-based monitoring of tumor burden using machine-learning-guided signal enrichment by Widman, Adam J., Shah, Minita, Frydendahl, Amanda, Halmos, Daniel, Khamnei, Cole C., Øgaard, Nadia, Rajagopalan, Srinivas, Arora, Anushri, Deshpande, Aditya, Hooper, William F., Quentin, Jean, Bass, Jake, Zhang, Mingxuan, Langanay, Theophile, Andersen, Laura, Steinsnyder, Zoe, Liao, Will, Rasmussen, Mads Heilskov, Henriksen, Tenna Vesterman, Jensen, Sarah Østrup, Nors, Jesper, Therkildsen, Christina, Sotelo, Jesus, Brand, Ryan, Schiffman, Joshua S., Shah, Ronak H., Cheng, Alexandre Pellan, Maher, Colleen, Spain, Lavinia, Krause, Kate, Frederick, Dennie T., den Brok, Wendie, Lohrisch, Caroline, Shenkier, Tamara, Simmons, Christine, Villa, Diego, Mungall, Andrew J., Moore, Richard, Zaikova, Elena, Cerda, Viviana, Kong, Esther, Lai, Daniel, Malbari, Murtaza S., Marton, Melissa, Manaa, Dina, Winterkorn, Lara, Gelmon, Karen, Callahan, Margaret K., Boland, Genevieve, Potenski, Catherine, Wolchok, Jedd D., Saxena, Ashish, Turajlic, Samra, Imielinski, Marcin, Berger, Michael F., Aparicio, Sam, Altorki, Nasser K., Postow, Michael A., Robine, Nicolas, Andersen, Claus Lindbjerg, Landau, Dan A.

“…In solid tumor oncology, circulating tumor DNA (ctDNA) is poised to transform care through accurate assessment of minimal residual disease (MRD) and…”
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Selective Autophagy of Mitochondria on a Ubiquitin-Endoplasmic-Reticulum Platform by Zachari, Maria, Gudmundsson, Sigurdur R, Li, Ziyue, Manifava, Maria, Cugliandolo, Fiorella, Shah, Ronak, Smith, Matthew, Stronge, James, Karanasios, Eleftherios, Piunti, Caterina, Kishi-Itakura, Chieko, Vihinen, Helena, Jokitalo, Eija, Guan, Jun-Lin, Buss, Folma, Smith, Andrew M, Walker, Simon A, Eskelinen, Eeva-Liisa, Ktistakis, Nicholas T

“…The dynamics and coordination between autophagy machinery and selective receptors during mitophagy are unknown. Also unknown is whether mitophagy depends on…”
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Gas- and bulk-based nonlinear pulse compression of 10 mJ and 50 W pulses of an ultrafast thin-disk amplifier by Manz, Jonas, Barbiero, Gaia, Klingebiel, Sandro, Rampp, Michael, Teisset, Catherine Y., Wang, Haochuan, Ertel, Dominik, Shah, Ronak N., Hoffmann, Martin, Saraceno, Clara J., Metzger, Thomas

“…We present a comparative study on nonlinear pulse compression of 10 mJ pulses from a thin-disk amplifier at 5 kHz in a multipass cell using both gaseous and…”
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A biomimetic approach to active self-microencapsulation of proteins in PLGA by Shah, Ronak B., Schwendeman, Steven P.

“…A biomimetic approach to organic solvent-free microencapsulation of proteins based on the self-healing capacity of poly (dl)-lactic-co-glycolic acid (PLGA)…”
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Predictors of Intraoperative Echocardiography: Analysis of The Society of Thoracic Surgeons Database by MacKay, Emily J, Zhang, Bo, Shah, Ronak M, Augoustides, John G, Groeneveld, Peter W, Desai, Nimesh D

“…Intraoperative transesophageal echocardiography (TEE) is associated with improved outcomes after cardiac surgery, but unexplained practice pattern variation…”
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Clinical utility of plasma cell-free DNA in pancreatic neuroendocrine neoplasms by Cowzer, Darren, Shah, Ronak H, Chou, Joanne F, Kundra, Ritika, Punn, Sippy, Fiedler, Laura, DeMore, April, Capanu, Marinela, Berger, Michael F, Reidy-Lagunes, Diane, Raj, Nitya

“…In advanced pancreatic neuroendocrine neoplasms (PanNEN), there are little data detailing the frequency of genetic alterations identified in cell free DNA…”
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