Výsledky vyhľadávania - "Schreiner, Bettina"

High-Dimensional Single-Cell Mapping of Central Nervous System Immune Cells Reveals Distinct Myeloid Subsets in Health, Aging, and Disease Autor Mrdjen, Dunja, Pavlovic, Anto, Hartmann, Felix J, Schreiner, Bettina, Utz, Sebastian G, Leung, Brian P, Lelios, Iva, Heppner, Frank L, Kipnis, Jonathan, Merkler, Doron, Greter, Melanie, Becher, Burkhard

“…Individual reports suggest that the central nervous system (CNS) contains multiple immune cell types with diverse roles in tissue homeostasis, immune defense,…”
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Dysregulation of the Cytokine GM-CSF Induces Spontaneous Phagocyte Invasion and Immunopathology in the Central Nervous System Autor Spath, Sabine, Komuczki, Juliana, Hermann, Mario, Pelczar, Pawel, Mair, Florian, Schreiner, Bettina, Becher, Burkhard

“…Chronic inflammatory diseases are influenced by dysregulation of cytokines. Among them, granulocyte macrophage colony stimulating factor (GM-CSF) is crucial…”
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The Cytokine GM-CSF Drives the Inflammatory Signature of CCR2+ Monocytes and Licenses Autoimmunity Autor Croxford, Andrew L, Lanzinger, Margit, Hartmann, Felix J, Schreiner, Bettina, Mair, Florian, Pelczar, Pawel, Clausen, Björn E, Jung, Steffen, Greter, Melanie, Becher, Burkhard

“…Granulocyte-macrophage colony-stimulating factor (GM-CSF) has emerged as a crucial cytokine produced by auto-reactive T helper (Th) cells that initiate tissue…”
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High-Dimensional Single-Cell Mapping of Central Nervous System Immune Cells Reveals Distinct Myeloid Subsets in Health, Aging, and Disease Autor Mrdjen, Dunja, Pavlovic, Anto, Hartmann, Felix J, Schreiner, Bettina, Utz, Sebastian G, Leung, Brian P, Lelios, Iva, Heppner, Frank L, Kipnis, Jonathan, Merkler, Doron, Greter, Melanie, Becher, Burkhard

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Pericytes regulate vascular immune homeostasis in the CNS Autor Török, Orsolya, Schreiner, Bettina, Schaffenrath, Johanna, Tsai, Hsing-Chuan, Maheshwari, Upasana, Stifter, Sebastian A, Welsh, Christina, Amorim, Ana, Sridhar, Sucheta, Utz, Sebastian G, Mildenberger, Wiebke, Nassiri, Sina, Delorenzi, Mauro, Aguzzi, Adriano, Han, May H, Greter, Melanie, Becher, Burkhard, Keller, Annika

“…Pericytes regulate the development of organ-specific characteristics of the brain vasculature such as the blood-brain barrier (BBB) and astrocytic end-feet…”
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IL-12 protects from psoriasiform skin inflammation Autor Kulig, Paulina, Musiol, Stephanie, Freiberger, Sandra Nicole, Schreiner, Bettina, Gyülveszi, Gabor, Russo, Giancarlo, Pantelyushin, Stanislav, Kishihara, Kenji, Alessandrini, Francesca, Kündig, Thomas, Sallusto, Federica, Hofbauer, Günther F.L., Haak, Stefan, Becher, Burkhard

“…Neutralization of the common p40-subunit of IL-12/23 in psoriasis patients has led to a breakthrough in the management of moderate to severe disease. Aside…”
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IL-9 as a mediator of Th17-driven inflammatory disease Autor Nowak, Elizabeth C, Weaver, Casey T, Turner, Henrietta, Begum-Haque, Sakhina, Becher, Burkhard, Schreiner, Bettina, Coyle, Anthony J, Kasper, Lloyd H, Noelle, Randolph J

“…We report that like other T cells cultured in the presence of transforming growth factor (TGF) beta, Th17 cells also produce interleukin (IL) 9. Th17 cells…”
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CNS myeloid DCs presenting endogenous myelin peptides 'preferentially' polarize CD4+ TH-17 cells in relapsing EAE Autor Bailey, Samantha L, Schreiner, Bettina, McMahon, Eileen J, Miller, Stephen D

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Astrocyte Depletion Impairs Redox Homeostasis and Triggers Neuronal Loss in the Adult CNS Autor Schreiner, Bettina, Romanelli, Elisa, Liberski, Pawel, Ingold-Heppner, Barbara, Sobottka-Brillout, Bettina, Hartwig, Tom, Chandrasekar, Vijay, Johannssen, Helge, Zeilhofer, Hanns Ulrich, Aguzzi, Adriano, Heppner, Frank, Kerschensteiner, Martin, Becher, Burkhard

“…Although the importance of reactive astrocytes during CNS pathology is well established, the function of astroglia in adult CNS homeostasis is less well…”
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Regulatory T Cells Restrain Pathogenic T Helper Cells during Skin Inflammation Autor Hartwig, Tom, Zwicky, Pascale, Schreiner, Bettina, Yawalkar, Nikhil, Cheng, Phil, Navarini, Alexander, Dummer, Reinhard, Flatz, Lukas, Conrad, Curdin, Schlapbach, Christoph, Becher, Burkhard

“…Psoriasis is a chronic relapsing, remitting interleukin (IL)-23/IL-17-driven skin disease mediated by the interplay of T cells and polymorphonuclear…”
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Cytomegalovirus primo-infection in Guillain-Barré syndrome during pregnancy, a case report of a very serious and rare case Autor Hänsel, Martin, Kalimeris, Stylianos, Schreiner, Bettina, Friedl, Susanne, Cannizzaro, Vincenzo, Keller, Emanuela, Haslinger, Christian, Brandi, Giovanna

“…Background Guillain-Barré syndrome (GBS) during pregnancy can be a very severe and life-threatening condition for both mother and child. GBS due to…”
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Acute leukoencephalopathy associated with daratumumab treatment in POEMS syndrome: a case report Autor Steinegger, Lukas, Nierobisch, Nathalie, De Vere-Tyndall, Anthony, Schreiner, Bettina, Roth, Patrick, Kappos, Ludwig, Kana, Veronika, Herwerth, Marina

“…Daratumumab, a monoclonal antibody against CD38, is increasingly used in the treatment of multiple myeloma, other hematological malignancies and autoimmune…”
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Editorial: New perspectives in the treatment of myasthenia gravis Autor Cortés-Vicente, Elena, Schreiner, Bettina, Saccà, Francesco, Narayanaswami, Pushpa

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Meningitis and epididymitis caused by Toscana virus infection imported to Switzerland diagnosed by metagenomic sequencing: a case report Autor Tschumi, Fabian, Schmutz, Stefan, Kufner, Verena, Heider, Maike, Pigny, Fiona, Schreiner, Bettina, Capaul, Riccarda, Achermann, Yvonne, Huber, Michael

“…Background We report a rare case of Toscana virus infection imported into Switzerland in a 23-year old man who travelled to Imperia (Italy) 10 days before…”
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Twin study reveals non-heritable immune perturbations in multiple sclerosis Autor Ingelfinger, Florian, Gerdes, Lisa Ann, Kavaka, Vladyslav, Krishnarajah, Sinduya, Friebel, Ekaterina, Galli, Edoardo, Zwicky, Pascale, Furrer, Reinhard, Peukert, Christian, Dutertre, Charles-Antoine, Eglseer, Klara Magdalena, Ginhoux, Florent, Flierl-Hecht, Andrea, Kümpfel, Tania, De Feo, Donatella, Schreiner, Bettina, Mundt, Sarah, Kerschensteiner, Martin, Hohlfeld, Reinhard, Beltrán, Eduardo, Becher, Burkhard

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Perspectives on cytokine-directed therapies in multiple sclerosis Autor Schreiner, Bettina, Becher, Burkhard

“…Multiple sclerosis (MS) is the most common inflammatory demyelinating disorder of the central nervous system (CNS). Over the past 10 years there has been a…”
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Anti-HMGCR myopathy mimicking facioscapulohumeral muscular dystrophy Autor Braun, Andreas Albert, Atiya, Monika, Göhner, Katja, Hortobagyi, Tibor, Burkhardt, Tobias, Schreiner, Bettina

“…Statin use can lead to various muscle-related issues, including benign creatine kinase (CK) elevations, myalgias, toxic myopathies, rhabdomyolysis, and…”
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Antigen Presentation in the CNS by Myeloid Dendritic Cells Drives Progression of Relapsing Experimental Autoimmune Encephalomyelitis Autor MILLER, STEPHEN D., McMAHON, EILEEN J., SCHREINER, BETTINA, BAILEY, SAMANTHA L.

“…:  Chronic progression of relapsing experimental autoimmune encephalomyelitis (R‐EAE), a mouse model of multiple sclerosis (MS), is dependent on the activation…”
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Diabetes insipidus and Guillain-Barré-like syndrome following CAR-T cell therapy: a case report Autor Koch, Christian, Fleischer, Juliane, Popov, Todor, Frontzek, Karl, Schreiner, Bettina, Roth, Patrick, Manz, Markus G., Unseld, Simone, Müller, Antonia M. S., Russkamp, Norman F.

“…BackgroundImmune effector cell-associated neurotoxicity syndrome (ICANS) is a common adverse event of CD19-directed chimeric antigen receptor (CAR) T cell…”
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Hot Topics on COVID-19 and Its Possible Association with Guillain-Barré Syndrome Autor Dietmann, Anelia, Ripellino, Paolo, Humm, Andrea M., Hundsberger, Thomas, Schreiner, Bettina, Théaudin, Marie, Scheidegger, Olivier

“…As the COVID-19 pandemic progresses, reports of neurological manifestations are increasing. However, despite a high number of case reports and case series on…”
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