Výsledky vyhľadávania - "Schouten, Marcel"

Inflammation, endothelium, and coagulation in sepsis Autor Schouten, Marcel, Wiersinga, Willem Joost, Levi, Marcel, Poll, Tom

“…Sepsis is a systemic response to infection, and symptoms are produced by host defense systems rather than by the invading pathogens. Amongst the most prominent…”
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Lipopolysaccharide Inhibits Th2 Lung Inflammation Induced by House Dust Mite Allergens in Mice Autor Daan de Boer, J., Roelofs, Joris J. T. H., de Vos, Alex F., de Beer, Regina, Schouten, Marcel, Hommes, Tijmen J., Hoogendijk, Arie J., de Boer, Onno J., Stroo, Ingrid, van der Zee, Jaring S., Veer, Cornelis van’t, van der Poll, Tom

“…The complex biology of asthma compels the use of more relevant human allergens, such as house dust mite (HDM), to improve the translation of animal models into…”
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The receptor for advanced glycation end products impairs host defense in pneumococcal pneumonia Autor van Zoelen, Marieke A D, Schouten, Marcel, de Vos, Alex F, Florquin, Sandrine, Meijers, Joost C M, Nawroth, Peter P, Bierhaus, Angelika, van der Poll, Tom

“…Streptococcus pneumoniae is the most common cause of community-acquired pneumonia. The receptor for advanced glycation end products (RAGE) is a multiligand…”
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Sepsis, Coagulation, and Antithrombin: Old Lessons and New Insights Autor Levi, Marcel, Schouten, Marcel, van der Poll, Tom

“…ABSTRACT Current insights in the pathogenesis of multiple organ dysfunction in patients with sepsis point to a pivotal role of inflammation and coagulation…”
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CCAAT/enhancer-binding protein δ facilitates bacterial dissemination during pneumococcal pneumonia in a platelet-activating factor receptor-dependent manner Autor Duitman, Janwillem, Schouten, Marcel, Groot, Angelique P, Borensztajn, Keren S, Daalhuisen, Joost B, Florquin, Sandrine, van der Poll, Tom, Spek, C Arnold

“…CCAAT/enhancer-binding protein δ (C/EBPδ) recently emerged as an essential player in the inflammatory response to bacterial infections. C/EBPδ levels increase…”
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Protease-activated receptor-1 impairs host defense in murine pneumococcal pneumonia: a controlled laboratory study Autor Schouten, Marcel, van't Veer, Cornelis, Roelofs, Joris JTH, Levi, Marcel, van der Poll, Tom

“…Introduction Streptococcus pneumoniae is the most common causative pathogen in community-acquired pneumonia. Protease-activated receptor-1 (PAR-1) is expressed…”
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Role played by Toll-like receptors 2 and 4 in lipoteichoic acid-induced lung inflammation and coagulation Autor Dessing, Mark C, Schouten, Marcel, Draing, Christian, Levi, Marcel, von Aulock, Sonja, van der Poll, Tom

“…The cell wall of Streptococcus pneumoniae consists of lipoteichoic acid (LTA), which is released when pneumococci are killed by either the host immune system…”
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Osteopontin impairs host defense during pneumococcal pneumonia Autor van der Windt, Gerritje J W, Hoogendijk, Arie J, Schouten, Marcel, Hommes, Tijmen J, de Vos, Alex F, Florquin, Sandrine, van der Poll, Tom

“…Streptococcus pneumoniae is the most frequently isolated pathogen responsible for community-acquired pneumonia. Osteopontin is involved in inflammation during…”
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Recombinant activated protein C attenuates coagulopathy and inflammation when administered early in murine pneumococcal pneumonia Autor Schouten, Marcel, van 't Veer, Cornelis, Roelofs, Joris J T H, Gerlitz, Bruce, Grinnell, Brian W, Levi, Marcel, van der Poll, Tom

“…Recombinant human activated protein C (APC), which has both anticoagulant and anti-inflammatory properties, improves survival of patients with severe sepsis…”
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Overexpression of the Endothelial Protein C Receptor Is Detrimental during Pneumonia-Derived Gram-negative Sepsis (Melioidosis) Autor Kager, Liesbeth M., Schouten, Marcel, Wiersinga, W. Joost, de Boer, J. Daan, Lattenist, Lionel C. W., Roelofs, Joris J. T. H., Meijers, Joost C. M., Levi, Marcel, Dondorp, Arjen M., Esmon, Charles T., van 't Veer, Cornelis, van der Poll, Tom

“…The endothelial protein C receptor (EPCR) enhances anticoagulation by accelerating activation of protein C to activated protein C (APC) and mediates…”
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Thrombophilia and outcome in severe infection and sepsis Autor Hofstra, Jorrit-Jan, Schouten, Marcel, Levi, Marcel

“…Thrombophilia is associated with a prohemostatic state and consequently with an increased tendency to develop thrombosis. In severe infection and sepsis,…”
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Depression, anxiety and quality of life of hemodialysis patients before and during the COVID-19 pandemic Autor Nadort, Els, Rijkers, Nadine, Schouten, Robbert W., Hoogeveen, Ellen K., Bos, Willem J.W., Vleming, Louis Jean, Westerman, Michiel, Schouten, Marcel, Dekker, Marijke J.E., Smets, Yves F.C., Shaw, Prataap Chandie, Farhat, Karima, Dekker, Friedo W., van Oppen, Patricia, Siegert, Carl E.H., Broekman, Birit F.P.

“…To investigate the impact of the coronavirus pandemic on mental health in hemodialysis patients, we assessed depression, anxiety and quality of life with valid…”
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Internet-based treatment for depressive symptoms in hemodialysis patients: A cluster randomized controlled trial Autor Nadort, Els, Schouten, Robbert W., Boeschoten, Rosa E., Smets, Yves, Chandie Shaw, Prataap, Vleming, Louis Jean, Dekker, Marijke J.E., Westerman, Michiel, Hoogeveen, Ellen K., Bos, Willem J.W., Schouten, Marcel, Farhat, Karima, Dekker, Friedo W., van Oppen, Patricia, Broekman, Birit F.P., Siegert, Carl E.H.

“…To investigate the effectiveness of a guided internet-based self-help intervention for hemodialysis patients with depressive symptoms. Chronic hemodialysis…”
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Thrombocytopenia impairs host defense during murine Streptococcus pneumoniae pneumonia Autor van den Boogaard, Florry E, Schouten, Marcel, de Stoppelaar, Sacha F, Roelofs, Joris J T H, Brands, Xanthe, Schultz, Marcus J, van't Veer, Cornelis, van der Poll, Tom

“…Streptococcus pneumoniae is the most common causative pathogen in community-acquired pneumonia. In patients, thrombocytopenia is correlated with an adverse…”
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CD44 Is Protective during Hyperoxia-Induced Lung Injury Autor Windt, Gerritje J. W. van der, Schouten, Marcel, Zeerleder, Sacha, Florquin, Sandrine, Poll, Tom van der

“…Patients with acute lung injury or respiratory distress syndrome often require supplemental oxygen to maintain tissue oxygenation; however, this treatment can…”
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The cytoprotective effects of endogenous activated protein C reduce activation of coagulation during murine pneumococcal pneumonia and sepsis Autor Schouten, Marcel, van ‘t Veer, Cornelis, Poulussen, Nadia, Meijers, Joost C.M., Levi, Marcel, Esmon, Charles T., van der Poll, Tom

“…Streptococcus (S.) pneumoniae is the most common causative pathogen in community-acquired pneumonia and sepsis. Activated protein C (APC) has been implicated…”
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Factor v Leiden mutation in severe infection and sepsis Autor Levi, Marcel, Schouten, Marcel, van't Veer, Cees, van der Poll, Tom

“…In severe infection and sepsis, activation of coagulation frequently occurs, which contributes to the development of multiple organ dysfunction. Factor V…”
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Validation of Two Screening Tools for Anxiety in Hemodialysis Patients Autor Nadort, Els, van Geenen, Noëlle J. K., Schouten, Robbert W., Boeschoten, Rosa E., Chandie Shaw, Prataap, Vleming, Louis Jean, Schouten, Marcel, Farhat, Karima, Dekker, Friedo W., van Oppen, Patricia, Siegert, Carl E. H., Broekman, Birit F. P.

“…Background: Symptoms of anxiety are often unrecognized and untreated in dialysis patients. We investigated the diagnostic accuracy of two widely used screening…”
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Early activation of coagulation after allergen challenge in patients with allergic asthma Autor SCHOUTEN, M., VAN DE POL, M. A., LEVI, M., VAN DER POLL, T., VAN DER ZEE, J. S.

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The endothelial protein C receptor impairs the antibacterial response in murine pneumococcal pneumonia and sepsis Autor Schouten, Marcel, de Boer, J Daan, Kager, Liesbeth M, Roelofs, Joris J T H, Meijers, Joost C M, Esmon, Charles T, Levi, Marcel, van 't Veer, Cornelis, van der Poll, Tom

“…Pneumococcal pneumonia is a frequent cause of gram-positive sepsis and has a high mortality. The endothelial protein C receptor (EPCR) has been implicated in…”
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