Výsledky vyhľadávania - "Schott, Roland"

Outcomes of non-small cell lung cancer patients with non-V600E BRAF mutations: a series of case reports and literature review Autor Lazar, Raluca, Fischbach, Cathie, Schott, Roland, Somme, Laura

“…Non-small cell lung cancer (NSCLC) is the most prevalent form of lung cancer, accounting for approximately 85% of cases of lung cancer. The standard first-line…”
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Carboplatin plus etoposide versus topotecan as second-line treatment for patients with sensitive relapsed small-cell lung cancer: an open-label, multicentre, randomised, phase 3 trial Autor Baize, Nathalie, Monnet, Isabelle, Greillier, Laurent, Geier, Margaux, Lena, Hervé, Janicot, Henri, Vergnenegre, Alain, Crequit, Jacky, Lamy, Regine, Auliac, Jean-Bernard, Letreut, Jacques, Le Caer, Hervé, Gervais, Radj, Dansin, Eric, Madroszyk, Anne, Renault, Patrick-Aldo, Le Garff, Gwenaëlle, Falchero, Lionel, Berard, Henri, Schott, Roland, Saulnier, Patrick, Chouaid, Christos

“…Topotecan is currently the only drug approved in Europe in a second-line setting for the treatment of small-cell lung cancer. This study investigated whether…”
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Evolving Therapeutic Landscape of ROS1-Positive Non-Small Cell Lung Cancer: An Updated Review Autor Bischoff, Hervé, Gendarme, Sébastien, Somme, Laura, Chouaid, Christos, Schott, Roland

“…ROS1 gene rearrangements define a distinct molecular subtype of non-small cell lung cancer (NSCLC), occurring in approximately 2% of cases and frequently…”
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Survival outcomes of patients with metastatic non-small cell lung cancer receiving chemotherapy or immunotherapy as first-line in a real-life setting Autor Belaroussi, Yaniss, Bouteiller, Fanny, Bellera, Carine, Pasquier, David, Perol, Maurice, Debieuvre, Didier, Filleron, Thomas, Girard, Nicolas, Schott, Roland, Mathoulin-Pélissier, Simone, Martin, Anne-Laure, Cousin, Sophie

“…Treatment of metastatic non-small cell lung cancer (mNSCLC) has been modified due to the development of immunotherapy. We assessed survival outcomes (overall…”
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Ellipsoid calculations versus manual tumor delineations for glioblastoma tumor volume evaluation Autor Le Fèvre, Clara, Sun, Roger, Cebula, Hélène, Thiery, Alicia, Antoni, Delphine, Schott, Roland, Proust, François, Constans, Jean-Marc, Noël, Georges

“…In glioblastoma, the response to treatment assessment is essentially based on the 2D tumor size evolution but remains disputable. Volumetric approaches were…”
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Real-world survival and prognostic factors in WHO 2021 classified gliomas treated with chemo-radiotherapy Autor Bilski, Mateusz, Noël, Georges, Smółka, Krzysztof, Kuncewicz, Katarzyna, Kuźnicki, Wojciech, Feuvret, Loic, Korab, Katarzyna, Peszyńska-Piorun, Magdalena, Korona, Paweł, Baranowska, Izabela, Suleja, Agata, Le Fevre, Clara, Schott, Roland, Somme, Laura, Chabli, Salma, Mesny, Emmanuel, Mastroleo, Federico, Kotecha, Rupesh, Jurkiewicz, Jakub, Fijuth, Jacek, Jereczek-Fossa, Barbara Alicja, Krystkiewicz, Kamil, Harat, Maciej, Kuncman, Łukasz

“…The 2021 WHO glioma classification integrates molecular profiling, but outcome data for these patients are limited. We retrospectively analyzed 179 patients…”
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Outcomes of Patients with Non-Small Cell Lung Cancer and Brain Metastases Treated with the Upfront Single Agent Pembrolizumab: A Retrospective and Multicentric Study of the ESCKEYP GFPC Cohort Autor Nannini, Simon, Guisier, Florian, Curcio, Hubert, Ricordel, Charles, Demontrond, Pierre, Abdallahoui, Safa, Baloglu, Seyyid, Greillier, Laurent, Chouaid, Christos, Schott, Roland

“…Non-small cell lung cancer (NSCLC) is the most common cause of brain metastasis (BM). Little is known about immune checkpoint inhibitor activity in the central…”
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p16 Immunohistochemical Expression as a Surrogate Assessment of CDKN2A Alteration in Gliomas Leading to Prognostic Significances Autor Geyer, Lucas, Wolf, Thibaut, Chenard, Marie-Pierre, Cebula, Helene, Schott, Roland, Noel, Georges, Guerin, Eric, Pencreach, Erwan, Reita, Damien, Entz-Werlé, Natacha, Lhermitte, Benoît

“…CDKN2A is a tumor suppressor gene encoding the p16 protein, a key regulator of the cell cycle. CDKN2A homozygous deletion is a central prognostic factor for…”
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A randomized phase I study comparing the pharmacokinetics of a bevacizumab (HD204) biosimilar to European Union- and United States of America-sourced bevacizumab Autor Demarchi, Martin, Coliat, Pierre, Barthelemy, Philippe, Schott, Roland, BenAbdelghani, Meher, Kim, Michael, Hii, Jocelyn Chung Shii, Feyaerts, Peggy, Ang, Felicia Rui Xia, Derde, Marie Paule, Deforce, Filip, Petit, Thierry, Schwabe, Chris, Wynne, Chris, Park, Lisa Soyeon, Pivot, Xavier

“…Purpose This first-in-human study was designed to evaluate the pharmacokinetic (PK) equivalence between HD204 and the European Union (EU)-sourced bevacizumab,…”
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Chemotherapy impairs skeletal muscle mitochondrial homeostasis in early breast cancer patients Autor Mallard, Joris, Hucteau, Elyse, Charles, Anne‐Laure, Bender, Laura, Baeza, Claire, Pélissie, Mathilde, Trensz, Philippe, Pflumio, Carole, Kalish‐Weindling, Michal, Gény, Bernard, Schott, Roland, Favret, Fabrice, Pivot, Xavier, Hureau, Thomas J., Pagano, Allan F.

“…Background Chemotherapy is extensively used to treat breast cancer and is associated with skeletal muscle deconditioning, which is known to reduce patients'…”
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Solitary acrometastasis of the phalanx as initial presentation of an oligometastatic Kirsten rat sarcoma viral oncogene homolog-mutated lung adenocarcinoma: a case report Autor Pușcașu, Alexandra-Ioana, Moinard-Butot, Fabien, Antoni, Delphine, Schott, Roland, Somme, Laura

“…Background Acrometastasis is an uncommon finding in non-small cell lung cancer and is usually a sign of multimetastatic disease. Few case reports have…”
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Outcome of lung oligometastatic patients treated with stereotactic body irradiation Autor Virbel, Guillaume, Cox, David G., Olland, Anne, Falcoz, Pierre-Emmanuel, Le Fevre, Clara, Schott, Roland, Antoni, Delphine, Noel, Georges

“…The oligometastatic stage is an intermediate stage of cancer between the localized stage and polymetastatic stage. The prognosis of patients in this stage also…”
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A single chemotherapy administration induces muscle atrophy, mitochondrial alterations and apoptosis in breast cancer patients Autor Mallard, Joris, Hucteau, Elyse, Bender, Laura, Moinard‐Butot, Fabien, Rochelle, Emma, Boutonnet, Lauréline, Grandperrin, Antoine, Schott, Roland, Pflumio, Carole, Trensz, Philippe, Kalish‐Weindling, Michal, Charles, Anne‐Laure, Gény, Bernard, Favret, Fabrice, Pivot, Xavier, Hureau, Thomas J., Pagano, Allan F.

“…Background Breast cancer patients are commonly treated with sequential administrations of epirubicin–cyclophosphamide (EC) and paclitaxel (TAX). The chronic…”
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Retrospective comparison of chemoradiotherapy followed by adjuvant chemotherapy, with or without prior gliadel implantation (carmustine) after initial surgery in patients with newly diagnosed high-grade gliomas Autor Noël, Georges, Schott, Roland, Froelich, Sébastien, Gaub, Marie-Pierre, Boyer, Patrick, Fischer-Lokou, David, Dufour, Patrick, Kehrli, Pierre, Maitrot, Daniel

“…Retrospective study of patients treated for high-grade glioma, with or without biodegradable carmustine wafers and according to the Stupp protocol. Between May…”
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Utility of serum anti‐cetuximab immunoglobulin E levels to identify patients at a high risk of severe hypersensitivity reaction to cetuximab Autor Dupont, Benoît, Mariotte, Delphine, Dugué, Audrey E., Clarisse, Bénédicte, Grellard, Jean‐Michel, Babin, Emmanuel, Chauffert, Bruno, Dakpé, Stéphanie, Moldovan, Cristian, Bouhier‐Leporrier, Karine, Reimund, Jean‐Marie, Di Fiore, Frederic, Zanetta, Sylvie, Mailliez, Audrey, Do, Pascal, Peytier, Annie, Galais, Marie‐Pierre, Florescu, Carmen, Schott, Roland, Le Mauff, Brigitte, Gervais, Radj

“…Aim Cetuximab is an anti‐epidermal growth factor receptor antibody used for the treatment of metastatic colorectal cancer and head and neck cancer…”
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Bone metastases from a 1p/19q codeleted and IDH1-mutant anaplastic oligodendroglioma: a case report Autor Burgy, Mickaël, Chenard, Marie-Pierre, Noël, Georges, Bourahla, Khalil, Schott, Roland

“…Background Oligodendroglioma is a rare type of primary brain tumor which, like other malignant gliomas, metastasizes very rarely even when in high-grade form…”
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Evolution of Physical Status From Diagnosis to the End of First-Line Treatment in Breast, Lung, and Colorectal Cancer Patients: The PROTECT-01 Cohort Study Protocol Autor Mallard, Joris, Hucteau, Elyse, Schott, Roland, Petit, Thierry, Demarchi, Martin, Belletier, Christine, Ben Abdelghani, Meher, Carinato, Hélène, Chiappa, Pascale, Fischbach, Cathie, Kalish-Weindling, Michal, Bousinière, Audren, Dufour, Stéphane, Favret, Fabrice, Pivot, Xavier, Hureau, Thomas J., Pagano, Allan F.

“…Background: Cancer cachexia and exacerbated fatigue represent two hallmarks in cancer patients, negatively impacting their exercise tolerance and ultimately…”
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An Innovative Fluorescent Semi-quantitative Methylation-specific PCR Method for the Determination of MGMT Promoter Methylation is Reflecting Intra-tumor Heterogeneity Autor Nguyen, Aurelia, Legrain, Michele, Noel, Georges, Coca, Andres, Meyer Ea, Nicolos, Schott, Roland, Lasthaus, Christelle, Chenard, Marie Pierrette, Gaub, Marie Pierre, Lessinger, Jean Marc, Guenot, Dominique, Entz-Werle, Natacha

“…High grade gliomas (HGG) are usually associated with a very dismal prognosis, which was moderately improving in the last decade with the introduction of the…”
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Prognostic value of health‐related quality of life for death risk stratification in patients with unresectable glioblastoma Autor Paquette, Brice, Vernerey, Dewi, Chauffert, Bruno, Dabakuyo, Sandrine, Feuvret, Loic, Taillandier, Luc, Frappaz, Didier, Taillia, Hervé, Schott, Roland, Ducray, François, Fabbro, Michel, Tennevet, Isabelle, Ghiringhelli, François, Guillamo, Jean‐sébastien, Durando, Xavier, Castera, Daniel, Frenay, Marc, Campello, Chantal, Dalban, Cécile, Skrzypski, Jérome, Chinot, Olivier, Anota, Amélie, Bonnetain, Franck

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Immune-related aseptic meningitis and strategies to manage immune checkpoint inhibitor therapy: a systematic review Autor Nannini, Simon, Koshenkova, Larysa, Baloglu, Seyyid, Chaussemy, Dominique, Noël, Georges, Schott, Roland

“…Introduction Immune checkpoint inhibitors (ICIs) can induce adverse neurological effects. Due to its rarity as an adverse effect, meningitis has been poorly…”
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