Výsledky vyhľadávania - "Schaaf, H. Simon"

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    Multidrug-resistant and extensively drug-resistant tuberculosis: a threat to global control of tuberculosis Autor Gandhi, Neel R, Nunn, Paul, Dheda, Keertan, Schaaf, H Simon, Zignol, Matteo, van Soolingen, Dick, Jensen, Paul, Bayona, Jaime

    ISSN: 0140-6736, 1474-547X, 1474-547X
    Vydavateľské údaje: Kidlington Elsevier Ltd 22.05.2010
    Vydané v The Lancet (British edition) (22.05.2010)
    “…Although progress has been made to reduce global incidence of drug-susceptible tuberculosis, the emergence of multidrug-resistant (MDR) and extensively…”
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    Levofloxacin Preventive Treatment in Children Exposed to MDR Tuberculosis Autor Hesseling, Anneke C., Purchase, Susan E., Martinson, Neil A., Fairlie, Lee, Schaaf, H. Simon, Brigden, Joanna, Staples, Suzanne, Gibb, Diana M., Garcia-Prats, Anthony, Conradie, Francesca, McGowan, Charlotte, Layton, Charlotte, Batist, Elize, Demers, Anne-Marie, Nyamathe, Samukelisiwe, Frigati, Lisa, Turner, Rebecca, Duong, Trinh, Seddon, James A.

    ISSN: 0028-4793, 1533-4406, 1533-4406
    Vydavateľské údaje: United States Massachusetts Medical Society 19.12.2024
    Vydané v The New England journal of medicine (19.12.2024)
    “…In this randomized, controlled trial involving children with household exposure to multidrug-resistant tuberculosis, levofloxacin led to a lower incidence of…”
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    Pharmacokinetics and Safety of Clofazimine in Children With Rifampicin-Resistant Tuberculosis Autor Hughes, Jennifer A, Solans, Belén P, Garcia-Prats, Anthony J, Draper, Heather R, Schaaf, H Simon, Nielsen, James C, Nortier, Elri, Courtney, Ingrid, Palmer, Megan, van der Laan, Louvina, Savic, Radojka M, Hesseling, Anneke C

    ISSN: 0022-1899, 1537-6613, 1537-6613
    Vydavateľské údaje: US Oxford University Press 15.05.2025
    Vydané v The Journal of infectious diseases (15.05.2025)
    “…Abstract Background We described the pharmacokinetics and safety of clofazimine in children treated for multidrug/rifampicin-resistant tuberculosis…”
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    Experiences of children and their caregivers affected by multidrug-resistant tuberculosis in Cape Town, South Africa Autor Mcinziba, Abenathi, Wademan, Dillon T., Zimri, Klassina, Jacobs, Stephanie, Mcimeli, Khanyisa, Schaaf, H. Simon, Hesseling, Anneke C., Seddon, James A., Wilkinson, Thomas, Hoddinott, Graeme

    ISSN: 1932-6203, 1932-6203
    Vydavateľské údaje: United States Public Library of Science 19.05.2025
    Vydané v PloS one (19.05.2025)
    “…Approximately 30,000 children (<15 years) develop multidrug-resistant (MDR) tuberculosis (TB) each year. MDR-TB severely impacts the lives of children and…”
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    Treatment outcomes for children with multidrug-resistant tuberculosis: a systematic review and meta-analysis Autor Ettehad, Dena, Schaaf, H Simon, Seddon, James A, Cooke, Graham S, Ford, Nathan

    ISSN: 1473-3099, 1474-4457, 1474-4457
    Vydavateľské údaje: London Elsevier Ltd 01.06.2012
    Vydané v The Lancet infectious diseases (01.06.2012)
    “…Paediatric multidrug-resistant (MDR) tuberculosis is a public health challenge of growing concern, accounting for an estimated 15% of all global cases of MDR…”
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    The Diagnostic Accuracy of Chest Radiographic Features for Pediatric Intrathoracic Tuberculosis Autor Palmer, Megan, Gunasekera, Kenneth S, van der Zalm, Marieke M, Morrison, Julie, Simon Schaaf, H, Goussard, Pierre, Hesseling, Anneke C, Walters, Elisabetta, Seddon, James A

    ISSN: 1537-6591, 1537-6591
    Vydavateľské údaje: United States 29.09.2022
    Vydané v Clinical infectious diseases (29.09.2022)
    “…The chest radiograph (CR) remains a key tool in the diagnosis of pediatric tuberculosis (TB). In children with presumptive intrathoracic TB, we aimed to…”
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    Children deserve simple, short, safe, and effective treatment for rifampicin-resistant tuberculosis Autor Garcia-Prats, Anthony J, Hoddinott, Graeme, Howell, Pauline, Hughes, Jennifer, Jean-Philippe, Patrick, Kim, Soyeon, Palmer, Megan, Schaaf, H Simon, Seddon, James A, Svensson, Elin, Hesseling, Anneke C

    ISSN: 1473-3099, 1474-4457, 1474-4457
    Vydavateľské údaje: United States Elsevier Ltd 01.07.2023
    Vydané v The Lancet infectious diseases (01.07.2023)
    “…On the basis of emerging results from pivotal trials, in December 2022, WHO recommended a 6-month, once-per-day regimen of bedaquiline, pretomanid, linezolid,…”
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    Pharmacokinetics, optimal dosing, and safety of linezolid in children with multidrug-resistant tuberculosis: Combined data from two prospective observational studies Autor Garcia-Prats, Anthony J., Schaaf, H. Simon, Draper, Heather R., Garcia-Cremades, Maria, Winckler, Jana, Wiesner, Lubbe, Hesseling, Anneke C., Savic, Rada M.

    ISSN: 1549-1676, 1549-1277, 1549-1676
    Vydavateľské údaje: United States Public Library of Science 30.04.2019
    Vydané v PLoS medicine (30.04.2019)
    “…Linezolid is increasingly important for multidrug-resistant tuberculosis (MDR-TB) treatment. However, among children with MDR-TB, there are no linezolid…”
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    Levofloxacin Population Pharmacokinetics in South African Children Treated for Multidrug-Resistant Tuberculosis Autor Denti, Paolo, Garcia-Prats, Anthony J, Draper, Heather R, Wiesner, Lubbe, Winckler, Jana, Thee, Stephanie, Dooley, Kelly E, Savic, Rada M, McIlleron, Helen M, Schaaf, H Simon, Hesseling, Anneke C

    ISSN: 1098-6596, 1098-6596
    Vydavateľské údaje: United States 01.02.2018
    Vydané v Antimicrobial agents and chemotherapy (01.02.2018)
    “…Levofloxacin is increasingly used in the treatment of multidrug-resistant tuberculosis (MDR-TB). There are limited pediatric pharmacokinetic data to inform…”
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    Global estimates and determinants of antituberculosis drug pharmacokinetics in children and adolescents: a systematic review and individual patient data meta-analysis Autor Gafar, Fajri, Wasmann, Roeland E, McIlleron, Helen M, Aarnoutse, Rob E, Schaaf, H Simon, Marais, Ben J, Agarwal, Dipti, Antwi, Sampson, Bang, Nguyen D, Bekker, Adrie, Bell, David J, Chabala, Chishala, Choo, Louise, Davies, Geraint R, Day, Jeremy N, Dayal, Rajeshwar, Denti, Paolo, Donald, Peter R, Engidawork, Ephrem, Garcia-Prats, Anthony J, Gibb, Diana, Graham, Stephen M, Hesseling, Anneke C, Heysell, Scott K, Idris, Misgana I, Kabra, Sushil K, Kinikar, Aarti, Kumar, Agibothu K Hemanth, Kwara, Awewura, Lodha, Rakesh, Magis-Escurra, Cecile, Martinez, Nilza, Mathew, Binu S, Mave, Vidya, Mduma, Estomih, Mlotha-Mitole, Rachel, Mpagama, Stellah G, Mukherjee, Aparna, Nataprawira, Heda M, Peloquin, Charles A, Pouplin, Thomas, Ramachandran, Geetha, Ranjalkar, Jaya, Roy, Vandana, Ruslami, Rovina, Shah, Ira, Singh, Yatish, Sturkenboom, Marieke G G, Svensson, Elin M, Swaminathan, Soumya, Thatte, Urmila, Thee, Stephanie, Thomas, Tania A, Tikiso, Tjokosela, Touw, Daan J, Turkova, Anna, Velpandian, Thirumurthy, Verhagen, Lilly M, Winckler, Jana L, Yang, Hongmei, Yunivita, Vycke, Taxis, Katja, Stevens, Jasper, Alffenaar, Jan-Willem C

    ISSN: 1399-3003, 1399-3003
    Vydavateľské údaje: England 01.03.2023
    Vydané v The European respiratory journal (01.03.2023)
    “…Suboptimal exposure to antituberculosis (anti-TB) drugs has been associated with unfavourable treatment outcomes. We aimed to investigate estimates and…”
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    Pharmacokinetics, Safety, and Dosing of Novel Pediatric Levofloxacin Dispersible Tablets in Children with Multidrug-Resistant Tuberculosis Exposure Autor Garcia-Prats, Anthony J, Purchase, Susan E, Osman, Muhammad, Draper, Heather R, Schaaf, H Simon, Wiesner, Lubbe, Denti, Paolo, Hesseling, Anneke C

    ISSN: 1098-6596, 1098-6596
    Vydavateľské údaje: United States 01.04.2019
    Vydané v Antimicrobial agents and chemotherapy (01.04.2019)
    “…This study characterized the pharmacokinetics of novel 100-mg levofloxacin dispersible tablets in 24 children aged <5 years who had household…”
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    Hearing loss in patients on treatment for drug-resistant tuberculosis Autor Seddon, James A, Godfrey-Faussett, Peter, Jacobs, Kayleen, Ebrahim, Adam, Hesseling, Anneke C, Schaaf, H Simon

    ISSN: 1399-3003, 1399-3003
    Vydavateľské údaje: England 01.11.2012
    Vydané v The European respiratory journal (01.11.2012)
    “…The treatment of drug-resistant (DR)-tuberculosis (TB) necessitates the use of second-line injectable anti-TB drugs which are associated with hearing loss…”
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    Childhood Pulmonary Tuberculosis: Old Wisdom and New Challenges Autor Marais, Ben J, Gie, Robert P, Schaaf, H. Simon, Beyers, Nulda, Donald, Peter R, Starke, Jeff R

    ISSN: 1073-449X, 1535-4970
    Vydavateľské údaje: New York, NY Am Thoracic Soc 15.05.2006
    “…Childhood tuberculosis is neglected in endemic areas with resource constraints, as children are considered to develop mild forms of disease and to contribute…”
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    Pharmacokinetics and Dose Optimization Strategies of Para-Aminosalicylic Acid in Children with Rifampicin-Resistant Tuberculosis Autor van der Laan, Louvina E, Garcia-Prats, Anthony J, Schaaf, H Simon, Chirehwa, Maxwell, Winckler, Jana L, Mao, Jun, Draper, Heather R, Wiesner, Lubbe, Norman, Jennifer, McIlleron, Helen, Donald, Peter R, Hesseling, Anneke C, Denti, Paolo

    ISSN: 1098-6596, 1098-6596
    Vydavateľské údaje: United States 21.06.2022
    Vydané v Antimicrobial agents and chemotherapy (21.06.2022)
    “…Treatment options for children with Rifampicin-resistant tuberculosis (RR-TB) remain limited, and para-aminosalicylic acid (PAS) is still a relevant component…”
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