Výsledky vyhľadávania - "Salvato, Maria S."

The Role of Platelets in the Pathogenesis of Viral Hemorrhagic Fevers Autor Zapata, Juan C., Cox, Dermot, Salvato, Maria S.

“…Viral hemorrhagic fevers (VHF) are acute zoonotic diseases that, early on, seem to cause platelet destruction or dysfunction. Here we present the four major…”
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ICTV Virus Taxonomy Profile: Arenaviridae 2023 Autor Radoshitzky, Sheli R, Buchmeier, Michael J, Charrel, Rémi N, Gonzalez, Jean-Paul J, Günther, Stephan, Hepojoki, Jussi, Kuhn, Jens H, Lukashevich, Igor S, Romanowski, Víctor, Salvato, Maria S, Sironi, Manuela, Stenglein, Mark D, Torre, Juan Carlos de la

“…is a family for ambisense RNA viruses with genomes of about 10.5 kb that infect mammals, snakes, and fish. The arenavirid genome consists of two or three…”
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ICTV Virus Taxonomy Profile: Arenaviridae Autor Radoshitzky, Sheli R, Buchmeier, Michael J, Charrel, Rémi N, Clegg, J Christopher S, Gonzalez, Jean-Paul J, Günther, Stephan, Hepojoki, Jussi, Kuhn, Jens H, Lukashevich, Igor S, Romanowski, Víctor, Salvato, Maria S, Sironi, Manuela, Stenglein, Mark D, de la Torre, Juan Carlos, Ictv Report Consortium

“…Members of the family Arenaviridae produce enveloped virions containing genomes consisting of two or three single-stranded RNA segments totalling about 10.5…”
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The Key Roles of Interferon Lambda in Human Molecular Defense against Respiratory Viral Infections Autor Lozhkov, Alexey A., Klotchenko, Sergey A., Ramsay, Edward S., Moshkoff, Herman D., Moshkoff, Dmitry A., Vasin, Andrey V., Salvato, Maria S.

“…Interferons (IFN) are crucial for the innate immune response. Slightly more than two decades ago, a new type of IFN was discovered: the lambda IFN (type III…”
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T-Cell Response to Viral Hemorrhagic Fevers Autor Perdomo-Celis, Federico, Salvato, Maria S., Medina-Moreno, Sandra, Zapata, Juan C.

“…Viral hemorrhagic fevers (VHF) are a group of clinically similar diseases that can be caused by enveloped RNA viruses primarily from the families Arenaviridae,…”
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Safety, immunogenicity, and efficacy of the ML29 reassortant vaccine for Lassa fever in small non-human primates Autor Lukashevich, Igor S., Carrion, Ricardo, Salvato, Maria S., Mansfield, Keith, Brasky, Kathleen, Zapata, Juan, Cairo, Cristiana, Goicochea, Marco, Hoosien, Gia E., Ticer, Anysha, Bryant, Joseph, Davis, Harry, Hammamieh, Rasha, Mayda, Maria, Jett, Marti, Patterson, Jean

“…A single injection of ML29 reassortant vaccine for Lassa fever induces low, transient viremia, and low or moderate levels of ML29 replication in tissues of…”
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A Single Dose of Modified Vaccinia Ankara Expressing Lassa Virus-like Particles Protects Mice from Lethal Intra-cerebral Virus Challenge Autor Salvato, Maria S., Domi, Arban, Guzmán-Cardozo, Camila, Medina-Moreno, Sandra, Zapata, Juan Carlos, Hsu, Haoting, McCurley, Nathanael, Basu, Rahul, Hauser, Mary, Hellerstein, Michael, Guirakhoo, Farshad

“…Lassa fever surpasses Ebola, Marburg, and all other hemorrhagic fevers except Dengue in its public health impact. Caused by Lassa virus (LASV), the disease is…”
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Improving the Breadth of the Host’s Immune Response to Lassa Virus Autor Zapata, Juan, Medina-Moreno, Sandra, Guzmán-Cardozo, Camila, Salvato, Maria

“…In 2017, the global Coalition for Epidemic Preparedness (CEPI) declared Lassa virus disease to be one of the world’s foremost biothreats. In January 2018,…”
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A live attenuated vaccine for Lassa fever made by reassortment of Lassa and Mopeia viruses Autor Lukashevich, Igor S, Patterson, Jean, Carrion, Ricardo, Moshkoff, Dmitry, Ticer, Anysha, Zapata, Juan, Brasky, Kathleen, Geiger, Robert, Hubbard, Gene B, Bryant, Joseph, Salvato, Maria S

“…Lassa virus (LASV) and Mopeia virus (MOPV) are closely related Old World arenaviruses that can exchange genomic segments (reassort) during coinfection. Clone…”
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Pathogenic Old World arenaviruses inhibit TLR2/Mal-dependent proinflammatory cytokines in vitro Autor Hayes, Melissa W, Carrion, Jr, Ricardo, Nunneley, Jerritt, Medvedev, Andrei E, Salvato, Maria S, Lukashevich, Igor S

“…Lymphocytic choriomeningitis virus (LCMV), the prototype arenavirus, and Lassa virus (LASV), the causative agent of Lassa fever (LF), have extensive strain…”
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Role of the Fas/FasL Pathway in HIV or SIV Disease Autor Poonia, Bhawna, Pauza, C David, Salvato, Maria S

“…Human immunodeficiency virus disease involves progressive destruction of host immunity leading to opportunistic infections and increased rates for…”
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Transcriptome Analysis of Human Peripheral Blood Mononuclear Cells Exposed to Lassa Virus and to the Attenuated Mopeia/Lassa Reassortant 29 (ML29), a Vaccine Candidate Autor Zapata, Juan Carlos, Carrion, Ricardo, Patterson, Jean L., Crasta, Oswald, Zhang, Yan, Mani, Sachin, Jett, Marti, Poonia, Bhawna, Djavani, Mahmoud, White, David M., Lukashevich, Igor S., Salvato, Maria S.

“…Lassa virus (LASV) is the causative agent of Lassa Fever and is responsible for several hundred thousand infections and thousands of deaths annually in West…”
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Genetic variation in vitro and in vivo of an attenuated Lassa vaccine candidate Autor Zapata, Juan C, Goicochea, Marco, Nadai, Yuka, Eyzaguirre, Lindsay M, Carr, Jean K, Tallon, Luke J, Sadzewicz, Lisa, Myers, Garry, Fraser, Claire M, Su, Qi, Djavani, Mahmoud, Lukashevich, Igor S, Salvato, Maria S

“…The attenuated Lassa vaccine candidate ML29 is a laboratory-produced reassortant between Lassa and Mopeia viruses, two Old World arenaviruses that differ by…”
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A ML29 reassortant virus protects guinea pigs against a distantly related Nigerian strain of Lassa virus and can provide sterilizing immunity Autor Carrion, Ricardo, Patterson, Jean L., Johnson, Curtis, Gonzales, Monica, Moreira, Carmen R., Ticer, Anysha, Brasky, Kathleen, Hubbard, Gene B., Moshkoff, Dmitry, Zapata, Juan, Salvato, Maria S., Lukashevich, Igor S.

“…Lassa virus (LASV) is responsible for the deaths of thousands of people in West Africa annually. Genetic diversity among LASV strains is the highest among the…”
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Lymphocytic choriomeningitis virus (LCMV) infection of macaques: A model for Lassa fever Autor Zapata, Juan C., Pauza, C. David, Djavani, Mahmoud M., Rodas, Juan D., Moshkoff, Dmitry, Bryant, Joseph, Ateh, Eugene, Garcia, Cybele, Lukashevich, Igor S., Salvato, Maria S.

“…► History of LCMV infections of primates (from mice to monkeys and man). ► Comparison of outcomes in murine and primate infections. ► Description of findings…”
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A recombinant Yellow Fever 17D vaccine expressing Lassa virus glycoproteins Autor Bredenbeek, Peter J., Molenkamp, Richard, Spaan, Willy J.M., Deubel, Vincent, Marianneau, Phillippe, Salvato, Maria S., Moshkoff, Dmitry, Zapata, Juan, Tikhonov, Ilia, Patterson, Jean, Carrion, Ricardo, Ticer, Anysha, Brasky, Kathleen, Lukashevich, Igor S.

“…The Yellow Fever Vaccine 17D (YFV17D) has been used as a vector for the Lassa virus glycoprotein precursor (LASV-GPC) resulting in construction of…”
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Early blood profiles of virus infection in a monkey model for Lassa fever Autor Djavani, Mahmoud M, Crasta, Oswald R, Zapata, Juan Carlos, Fei, Zhangjun, Folkerts, Otto, Sobral, Bruno, Swindells, Mark, Bryant, Joseph, Davis, Harry, Pauza, C David, Lukashevich, Igor S, Hammamieh, Rasha, Jett, Marti, Salvato, Maria S

“…Acute arenavirus disease in primates, like Lassa hemorrhagic fever in humans, begins with flu-like symptoms and leads to death approximately 2 weeks after…”
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Modulation of SIV and HIV DNA Vaccine Immunity by Fas-FasL Signaling Autor Yan, Jiabin, Zapata, Juan, Pauza, Charles, Salvato, Maria

“…Signaling through the Fas/Apo-1/CD95 death receptor is known to affect virus-specific cell-mediated immune (CMI) responses. We tested whether modulating the…”
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Arenavirus Z protein as an antiviral target: virus inactivation and protein oligomerization by zinc finger-reactive compounds Autor García, Cybele C, Djavani, Mahmoud, Topisirovic, Ivan, Borden, Katherine L B, Salvato, María S, Damonte, Elsa B

“…Several disulfide-based and azoic compounds have shown antiviral and virucidal properties against arenaviruses in virus yield-inhibition and inactivation…”
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Monocytes treated with human immunodeficiency virus Tat kill uninfected CD4(+) cells by a tumor necrosis factor-related apoptosis-induced ligand-mediated mechanism Autor Yang, Yida, Tikhonov, Ilia, Ruckwardt, Tracy J, Djavani, Mahmoud, Zapata, Juan Carlos, Pauza, C David, Salvato, Maria S

“…The human immunodeficiency virus (HIV) Tat protein has a critical role in viral transcription, but this study focuses on its additional role as an…”
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