Suchergebnisse - "Rokx, Casper"

An evaluation of COVID-19 serological assays informs future diagnostics and exposure assessment von GeurtsvanKessel, Corine H., Okba, Nisreen M. A., Igloi, Zsofia, Bogers, Susanne, Embregts, Carmen W. E., Laksono, Brigitta M., Leijten, Lonneke, Rokx, Casper, Rijnders, Bart, Rahamat-Langendoen, Janette, van den Akker, Johannes P. C., van Kampen, Jeroen J. A., van der Eijk, Annemiek A., van Binnendijk, Rob S., Haagmans, Bart, Koopmans, Marion

“… The world is entering a new era of the COVID-19 pandemic in which there is an increasing call for reliable antibody testing. To support decision making on the …”
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Selective cell death in HIV-1-infected cells by DDX3 inhibitors leads to depletion of the inducible reservoir von Rao, Shringar, Lungu, Cynthia, Crespo, Raquel, Steijaert, Thijs H., Gorska, Alicja, Palstra, Robert-Jan, Prins, Henrieke A. B., van Ijcken, Wilfred, Mueller, Yvonne M., van Kampen, Jeroen J. A., Verbon, Annelies, Katsikis, Peter D., Boucher, Charles A. B., Rokx, Casper, Gruters, Rob A., Mahmoudi, Tokameh

“… An innovative approach to eliminate HIV-1-infected cells emerging out of latency, the major hurdle to HIV-1 cure, is to pharmacologically reactivate viral …”
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Interferon-α2 Auto-antibodies in Convalescent Plasma Therapy for COVID-19 von Raadsen, Matthijs P., Gharbharan, Arvind, Jordans, Carlijn C. E., Mykytyn, Anna Z., Lamers, Mart M., van den Doel, Petra B., Endeman, Henrik, van den Akker, Johannes P. C., GeurtsvanKessel, Corine H., Koopmans, Marion P. G., Rokx, Casper, Goeijenbier, Marco, van Gorp, Eric C. M., Rijnders, Bart J. A., Haagmans, Bart L.

“… Purpose To study the effect of interferon-α2 auto-antibodies (IFN-α2 Abs) on clinical and virological outcomes in critically ill COVID-19 patients and the risk …”
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Global epidemiology of drug resistance after failure of WHO recommended first-line regimens for adult HIV-1 infection: a multicentre retrospective cohort study von Gregson, John, Tang, Michele, Ndembi, Nicaise, Hamers, Raph L, Rhee, Soo-Yon, Marconi, Vincent C, Diero, Lameck, Brooks, Katherine A, Theys, Kristof, Rinke de Wit, Tobias, Arruda, Monica, Garcia, Frederico, Monge, Susana, Günthard, Huldrych F, Hoffmann, Christopher J, Kanki, Phyllis J, Kumarasamy, Nagalingeshwaran, Kerschberger, Bernard, Mor, Orna, Charpentier, Charlotte, Todesco, Eva, Rokx, Casper, Gras, Luuk, Helvas, Elias K, Sunpath, Henry, Di Carlo, Domenico, Antinori, Antonio, Andreoni, Massimo, Latini, Alessandra, Mussini, Cristina, Aghokeng, Avelin, Sonnerborg, Anders, Neogi, Ujjwal, Fessel, William J, Agolory, Simon, Yang, Chunfu, Blanco, Jose L, Juma, James M, Smit, Erasmus, Schmidt, Daniel, Watera, Christine, Asio, Juliet, Kurungi, Wilford, Tostevin, Anna, El-Hay, Tal, Clumeck, Nathan, Goedhals, Dominique, Van Vuuren, Cloete, Bester, Philip A, Sabin, Caroline, Mukui, Irene, Santoro, MARIA M, Perno, Carlo F, Hunt, Gillian, Morris, Lynn, Camacho, Ricardo, De Oliveira, Tulio, Pillay, Deenan, Schulter, Eugene, Murakami-Ogasawara, Akio, Reyes-Terán, Gustavo, Romero, Karla, Avila-Rios, Santiago, Sirivichayakul, Sunee, Ruxrungtham, Kiat, Mekprasan, Suwanna, Dunn, David, Kaleebu, Pontiano, Raizes, Elliot, Kantor, Rami, Shafer, Robert W, Gupta, Ravindra K

“… Antiretroviral therapy (ART) is crucial for controlling HIV-1 infection through wide-scale treatment as prevention and pre-exposure prophylaxis (PrEP). Potent …”
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SARS-CoV-2 Neutralizing Human Antibodies Protect Against Lower Respiratory Tract Disease in a Hamster Model von Haagmans, Bart L, Noack, Danny, Okba, Nisreen M A, Li, Wentao, Wang, Chunyan, Bestebroer, Theo, de Vries, Rory, Herfst, Sander, de Meulder, Dennis, Verveer, Elwin, van Run, Peter, Lamers, Mart M, Rijnders, Bart, Rokx, Casper, van Kuppeveld, Frank, Grosveld, Frank, Drabek, Dubravka, Geurts van Kessel, Corine, Koopmans, Marion, Bosch, Berend Jan, Kuiken, Thijs, Rockx, Barry

“… Effective clinical intervention strategies for coronavirus disease 2019 (COVID-19) are urgently needed. Although several clinical trials have evaluated use of …”
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Ending HIV transmission in Europe von Hontelez, Jan A.C., Rokx, Casper

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Immunogenicity and reactogenicity of SARS-CoV-2 vaccines in people living with HIV in the Netherlands: A nationwide prospective cohort study von Hensley, Kathryn S., Jongkees, Marlou J., Geers, Daryl, GeurtsvanKessel, Corine H., Mueller, Yvonne M., Dalm, Virgil A. S. H., Papageorgiou, Grigorios, Steggink, Hanka, Gorska, Alicja, Bogers, Susanne, den Hollander, Jan G., Bierman, Wouter F. W., Gelinck, Luc B. S., Schippers, Emile F., Ammerlaan, Heidi S. M., van der Valk, Marc, van Vonderen, Marit G. A., Delsing, Corine E., Gisolf, Elisabeth H., Bruns, Anke H. W., Lauw, Fanny N., Berrevoets, Marvin A. H., Sigaloff, Kim C. E., Soetekouw, Robert, Branger, Judith, de Mast, Quirijn, Lammers, Adriana J. J., Lowe, Selwyn H., de Vries, Rory D., Katsikis, Peter D., Rijnders, Bart J. A., Brinkman, Kees, Roukens, Anna H. E., Rokx, Casper

“… Vaccines can be less immunogenic in people living with HIV (PLWH), but for SARS-CoV-2 vaccinations this is unknown. In this study we set out to investigate, …”
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Stopping HIV: The #aware.hiv project von Vliegenthart-Jongbloed, Klaske, Willemsen, Rens, Rokx, Casper

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Longitudinal assessment of COVID-19 vaccine immunogenicity in people with HIV stratified by CD4+ T-cell count in the Netherlands: A two-year follow-up study von Jongkees, Marlou J., Bogers, Susanne, de Vries, Rory D., GeurtsvanKessel, Corine H., Miranda Afonso, Pedro, Hensley, Kathryn S., Rijnders, Bart J. A., Brinkman, Kees, Rokx, Casper, Roukens, Anna H. E.

“… Although guidelines for COVID-19 additional vaccination strategies generally prioritise people with advanced HIV infection, recommendations vary globally, with …”
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Prospective individual patient data meta-analysis of two randomized trials on convalescent plasma for COVID-19 outpatients von Millat-Martinez, Pere, Gharbharan, Arvind, Alemany, Andrea, Rokx, Casper, Geurtsvankessel, Corine, Papageorgiou, Grigorios, van Geloven, Nan, Jordans, Carlijn, Groeneveld, Geert, Swaneveld, Francis, van der Schoot, Ellen, Corbacho-Monné, Marc, Ouchi, Dan, Piccolo Ferreira, Francini, Malchair, Pierre, Videla, Sebastian, García García, Vanesa, Ruiz-Comellas, Anna, Ramírez-Morros, Anna, Rodriguez Codina, Joana, Amado Simon, Rosa, Grifols, Joan-Ramon, Blanco, Julian, Blanco, Ignacio, Ara, Jordi, Bassat, Quique, Clotet, Bonaventura, Baro, Bàrbara, Troxel, Andrea, Zwaginga, Jaap Jan, Mitjà, Oriol, Rijnders, Bart J. A.

“… Data on convalescent plasma (CP) treatment in COVID-19 outpatients are scarce. We aimed to assess whether CP administered during the first week of symptoms …”
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The roles of the general practitioner and sexual health centre in HIV testing: comparative insights and impact on HIV incidence rates in the Rotterdam area, the Netherlands - a cross-sectional population-based study von Twisk, Denise E., Meima, Abraham, Richardus, Jan Hendrik, van Sighem, Ard, Rokx, Casper, den Hollander, Jan G., Götz, Hannelore M.

“… Background Access to HIV testing is crucial for detection, linkage to treatment, and prevention. In less urbanised areas, reliance on general practitioners …”
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Immunogenicity of an Additional mRNA-1273 SARS-CoV-2 Vaccination in People With HIV With Hyporesponse After Primary Vaccination von Jongkees, Marlou J, Geers, Daryl, Hensley, Kathryn S, Huisman, Wesley, GeurtsvanKessel, Corine H, Bogers, Susanne, Gommers, Lennert, Papageorgiou, Grigorios, Jochems, Simon P, den Hollander, Jan G, Schippers, Emile F, Ammerlaan, Heidi S M, Bierman, Wouter F W, van der Valk, Marc, Berrevoets, Marvin A H, Soetekouw, Robert, Langebeek, Nienke, Bruns, Anke H W, Leyten, Eliane M S, Sigaloff, Kim C E, van Vonderen, Marit G A, Delsing, Corine E, Branger, Judith, Katsikis, Peter D, Mueller, Yvonne M, de Vries, Rory D, Rijnders, Bart J A, Brinkman, Kees, Rokx, Casper, Roukens, Anna H E

“… Abstract Background The COVIH study is a prospective coronavirus disease 2019 (COVID-19) vaccination study in 1154 people with HIV (PWH), of whom 14% showed …”
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Risk of recurrent venous thromboembolism in patients with HIV infection: A nationwide cohort study von Rokx, Casper, Borjas Howard, Jaime F., Smit, Colette, Wit, Ferdinand W., Pieterman, Elise D., Reiss, Peter, Cannegieter, Suzanne C., Lijfering, Willem M., Meijer, Karina, Bierman, Wouter, Tichelaar, Vladimir, Rijnders, Bart J. A.

“… Multiple studies have described a higher incidence of venous thromboembolism (VTE) in people living with an HIV infection (PWH). However, data on the risk of …”
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Non-AIDS Events in Individuals With Spontaneous Control of HIV-1: A Systematic Review von Groenendijk, Albert L, Vos, Wilhelm A J W, Dos Santos, Jéssica C, Rokx, Casper, van der Ven, Andre J A M, Verbon, Annelies

“… Despite antiretroviral therapy (ART), people living with HIV (PLHIV) are at increased risk for non-AIDS-defining events (nADEs), including cardiovascular …”
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Author Correction: Prospective individual patient data meta-analysis of two randomized trials on convalescent plasma for COVID-19 outpatients von Millat-Martinez, Pere, Gharbharan, Arvind, Alemany, Andrea, Rokx, Casper, Geurtsvankessel, Corine, Papageorgiou, Grigorios, van Geloven, Nan, Jordans, Carlijn, Groeneveld, Geert, Swaneveld, Francis, van der Schoot, Ellen, Corbacho-Monné, Marc, Ouchi, Dan, Piccolo Ferreira, Francini, Malchair, Pierre, Videla, Sebastian, García García, Vanesa, Ruiz-Comellas, Anna, Ramírez-Morros, Anna, Rodriguez Codina, Joana, Amado Simon, Rosa, Grifols, Joan-Ramon, Blanco, Julian, Blanco, Ignacio, Ara, Jordi, Bassat, Quique, Clotet, Bonaventura, Baro, Bàrbara, Troxel, Andrea, Zwaginga, Jaap Jan, Mitjà, Oriol, Rijnders, Bart J. A.

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The efficacy and tolerability of latency-reversing agents in reactivating the HIV-1 reservoir in clinical studies: a systematic review von Debrabander, Quinten, Hensley, Kathryn S., Psomas, Christina K., Bramer, Wichor, Mahmoudi, Tokameh, van Welzen, Berend J., Verbon, Annelies, Rokx, Casper

“… Understanding the clinical potency of latency-reversing agents (LRAs) on the HIV-1 reservoir is useful to deploy future strategies. This systematic review …”
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Cohort profile: the Netherlands Cohort Study on Acute HIV infection (NOVA), a prospective cohort study of people with acute or early HIV infection who immediately initiate HIV treatment von Dijkstra, Maartje, Prins, Henrieke, Prins, Jan M, Reiss, Peter, Boucher, Charles, Verbon, Annelies, Rokx, Casper, de Bree, Godelieve

“… PurposeInitiation of combination antiretroviral therapy (cART) during acute or early HIV-infection (AEHI) limits the size of the viral reservoir and preserves …”
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Bryostatin-1 enhances the proliferation and functionality of exhausted CD8+ T cells by upregulating MAP Kinase 11 von Li, Ling, Zhao, Manzhi, van Meurs, Marjan, Brouwers-Haspels, Inge, den Dekker, Renske J. H., Wilmsen, Merel E. P., Grashof, Dwin G. B., van de Werken, Harmen J. G., Rao, Shringar, Rokx, Casper, Mueller, Yvonne M., Katsikis, Peter D.

“… Bryostatin-1, a potent agonist of the protein kinase C, has been studied for HIV and cancer therapies. In HIV research, it has shown anti-HIV effects during …”
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The 2000HIV study: Design, multi-omics methods and participant characteristics von Vos, Wilhelm A. J. W., Groenendijk, Albert L., Blaauw, Marc J. T., van Eekeren, Louise E., Navas, Adriana, Cleophas, Maartje C. P., Vadaq, Nadira, Matzaraki, Vasiliki, dos Santos, Jéssica C., Meeder, Elise M. G., Fröberg, Janeri, Weijers, Gert, Zhang, Yue, Fu, Jingyuan, ter Horst, Rob, Bock, Christoph, Knoll, Rainer, Aschenbrenner, Anna C., Schultze, Joachim, Vanderkerckhove, Linos, Hwandih, Talent, Wonderlich, Elizabeth R., Vemula, Sai V., van der Kolk, Mike, de Vet, Sterre C. P., Blok, Willem L., Brinkman, Kees, Rokx, Casper, Schellekens, Arnt F. A., de Mast, Quirijn, Joosten, Leo A. B., Berrevoets, Marvin A. H., Stalenhoef, Janneke E., Verbon, Annelies, van Lunzen, Jan, Netea, Mihai G., van der Ven, Andre J. A. M.

“… Even during long-term combination antiretroviral therapy (cART), people living with HIV (PLHIV) have a dysregulated immune system, characterized by persistent …”
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Online networks facilitating multidisciplinary healthcare: a novel strategy to curb COVID-19 von Prins, Henrieke, Knijp, Ineke, Hermanides, Gonneke, Blanker, Marco, Rokx, Casper

“… ObjectivesGlobal spread of COVID-19 at an unprecedented speed has heavily strained healthcare systems worldwide, and reliable alternatives to analogue …”
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