Výsledky vyhľadávania - "Rizavi, Hooriyah S."

MicroRNA Expression Is Down-Regulated and Reorganized in Prefrontal Cortex of Depressed Suicide Subjects Autor Smalheiser, Neil R., Lugli, Giovanni, Rizavi, Hooriyah S., Torvik, Vetle I., Turecki, Gustavo, Dwivedi, Yogesh

“…Recent studies suggest that alterations in expression of genes, including those which regulate neural and structural plasticity, may be crucial in the…”
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Abnormal protein and mRNA expression of inflammatory cytokines in the prefrontal cortex of depressed individuals who died by suicide Autor Pandey, Ghanshyam N., Rizavi, Hooriyah S., Zhang, Hui, Bhaumik, Runa, Ren, Xinguo

“…Depression and stress are major risk factors for suicidal behaviour, and some studies show abnormalities of proinflammatory cytokines in the serum and…”
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Abnormal gene and protein expression of inflammatory cytokines in the postmortem brain of schizophrenia patients Autor Pandey, Ghanshyam N., Rizavi, Hooriyah S., Zhang, Hui, Ren, Xinguo

“…Immune function abnormalities have been implicated in the pathophysiology of schizophrenia (SZ). This is primarily based on the observation that the levels of…”
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Toll-like receptors in the depressed and suicide brain Autor Pandey, Ghanshyam N., Rizavi, Hooriyah S., Ren, Xinguo, Bhaumik, Runa, Dwivedi, Yogesh

“…Abnormalities of the immune function in depression and suicide are based in part on the observation of increased levels of proinflammatory cytokines in the…”
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Proinflammatory cytokines in the prefrontal cortex of teenage suicide victims Autor Pandey, Ghanshyam N., Rizavi, Hooriyah S., Ren, Xinguo, Fareed, Jawed, Hoppensteadt, Debra A., Roberts, Rosalinda C., Conley, Robert R., Dwivedi, Yogesh

“…Teenage suicide is a major public health concern, but its neurobiology is not well understood. Proinflammatory cytokines play an important role in stress and…”
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Methylation and expression of glucocorticoid receptor exon-1 variants and FKBP5 in teenage suicide-completers Autor Rizavi, Hooriyah S., Khan, Omar S., Zhang, Hui, Bhaumik, Runa, Grayson, Dennis R., Pandey, Ghanshyam N.

“…A dysregulated hypothalamic-pituitary-adrenal (HPA) axis has repeatedly been demonstrated to play a fundamental role in psychiatric disorders and suicide, yet…”
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Brain-derived neurotrophic factor gene and protein expression in pediatric and adult depressed subjects Autor Pandey, Ghanshyam N., Dwivedi, Yogesh, Rizavi, Hooriyah S., Ren, Xinguo, Zhang, Hui, Pavuluri, Mani N.

“…Brain-derived neurotrophic factor (BDNF) is a member of a neurotrophin family and is involved in many physiological functions, including cell proliferation,…”
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Effects of alcohol and PARP inhibition on RNA ribosomal engagement in cortical excitatory neurons Autor Krishnan, Harish R., Vallerini, Gian Paolo, Gavin, Hannah E., Guizzetti, Marina, Rizavi, Hooriyah S., Gavin, David P., Sharma, Rajiv P.

“…We report on the effects of ethanol (EtOH) and Poly (ADP-ribose) polymerase (PARP) inhibition on RNA ribosomal engagement, as a proxy for protein translation,…”
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Differential H3K9me2 heterochromatin levels and concordant mRNA expression in postmortem brain tissue of individuals with schizophrenia, bipolar, and controls Autor Rizavi, Hooriyah S., Chase, Kayla A., Liu, Chunyu, Gavin, Hannah, Rosen, Cherise, Xia, Cuihua, Guidotti, Alessandro, Sharma, Rajiv P.

“…The existence of repressive and durable chromatin assemblies along gene promoters or networks, especially in the brain, is of theoretical and therapeutic…”
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Neurotrophin Receptor Activation and Expression in Human Postmortem Brain: Effect of Suicide Autor Dwivedi, Yogesh, Rizavi, Hooriyah S., Zhang, Hui, Mondal, Amal C., Roberts, Rosalinda C., Conley, Robert R., Pandey, Ghanshyam N.

“…The physiological functions of neurotrophins occur through binding to two receptors: pan75 neurotrophin receptor (p75 NTR) and a family of tropomyosin receptor…”
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Ethanol- and PARP-Mediated Regulation of Ribosome-Associated Long Non-Coding RNA (lncRNA) in Pyramidal Neurons Autor Rizavi, Hooriyah S., Gavin, Hannah E., Krishnan, Harish R., Gavin, David P., Sharma, Rajiv P.

“…Although, by definition, long noncoding RNAs (lncRNAs) are not translated, they are sometimes associated with ribosomes. In fact, some estimates suggest the…”
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Innate immunity in the postmortem brain of depressed and suicide subjects: Role of Toll-like receptors Autor Pandey, Ghanshyam N., Rizavi, Hooriyah S., Bhaumik, Runa, Ren, Xinguo

“…•The expression of several TLRs is increased in prefrontal cortex of depressed suicide subjects.•There is a dissociation in gene and protein expression of…”
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Brain-derived neurotrophic factor gene expression in pediatric bipolar disorder: effects of treatment and clinical response Autor Pandey, Ghanshyam N, Rizavi, Hooriyah S, Dwivedi, Yogesh, Pavuluri, Mani N

“…Pediatric bipolar disorder (PBD) is a major public health concern; however, little is known about the cellular and genetic factors that are involved in the…”
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Chemokines gene expression in the prefrontal cortex of depressed suicide victims and normal control subjects Autor Pandey, Ghanshyam N., Rizavi, Hooriyah S., Bhaumik, Runa, Zhang, Hui

“…•We found chemokines abnormalities in postmortem brain of depressed suicide subjects.•We found decreased mRNA levels of several chemokines in the brain of…”
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Increased protein and mRNA expression of corticotropin-releasing factor (CRF), decreased CRF receptors and CRF binding protein in specific postmortem brain areas of teenage suicide subjects Autor Pandey, Ghanshyam N., Rizavi, Hooriyah S., Bhaumik, Runa, Ren, Xinguo

“…•Abnormalities of HPA-axis are associated with depression and suicidal behavior.•CRF expression is increased in PFC, but not in HIPPO of teenage suicide…”
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Dysregulation of Protein Kinase C in Adult Depression and Suicide: Evidence From Postmortem Brain Studies Autor Pandey, Ghanshyam N, Sharma, Anuradha, Rizavi, Hooriyah S, Ren, Xinguo

“…Abstract Background Several lines of evidence suggest the abnormalities of protein kinase C (PKC) signaling system in mood disorders and suicide based…”
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Protein and mRNA expression of protein kinase C (PKC) in the postmortem brain of bipolar and schizophrenic subjects Autor Pandey, Ghanshyam N., Rizavi, Hooriyah S., Ren, Xinguo

“…Abnormalities of protein kinase C (PKC) have been implicated in the pathophysiology of bipolar (BP) illness. This is primarily based on studies of PKC in…”
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Proinflammatory cytokines and their membrane-bound receptors are altered in the lymphocytes of schizophrenia patients Autor Pandey, Ghanshyam N., Ren, Xinguo, Rizavi, Hooriyah S., Zhang, Hui

“…Abnormalities of protein levels of proinflammatory cytokines and their soluble receptors have been reported in the plasma/serum of schizophrenia (SZ) patients…”
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Regional Distribution and Relative Abundance of Serotonin2c Receptors in Human Brain: Effect of Suicide Autor Pandey, Ghanshyam N., Dwivedi, Yogesh, Ren, Xinguo, Rizavi, Hooriyah S., Faludi, Gabor, Sarosi, Andrea, Palkovits, Miklos

“…Abnormalities in serotonin receptor subtypes have been observed in the postmortem brain of suicide victims. We examined the regional distribution of serotonin…”
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Abnormal gene expression of proinflammatory cytokines and their membrane-bound receptors in the lymphocytes of depressed patients Autor Rizavi, Hooriyah S., Ren, Xinguo, Zhang, Hui, Bhaumik, Runa, Pandey, Ghanshyam N.

“…Abnormalities of protein levels of proinflammatory cytokines and their soluble receptors have been reported in plasma of depressed patients. In this study, we…”
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