Výsledky vyhľadávania - "Reynolds, James D"
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P7C3-A20 treatment one year after TBI in mice repairs the blood-brain barrier, arrests chronic neurodegeneration, and restores cognition
ISSN: 1091-6490, 1091-6490Vydavateľské údaje: United States 03.11.2020Vydané v Proceedings of the National Academy of Sciences - PNAS (03.11.2020)“…Chronic neurodegeneration in survivors of traumatic brain injury (TBI) is a major cause of morbidity, with no effective therapies to mitigate this progressive…”
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Optimizing post brain death vascularized composite graft quality through ex vivo restoration of S-nitrosothiol homeostasis
ISSN: 2045-2322, 2045-2322Vydavateľské údaje: London Nature Publishing Group UK 04.11.2025Vydané v Scientific reports (04.11.2025)“…A challenge in vascularized composite allotransplantation (VCA) is mitigating tissue damage within the composite secondary to brain death (BD). Loss of central…”
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Expert Diagnosis of Plus Disease in Retinopathy of Prematurity From Computer-Based Image Analysis
ISSN: 2168-6173, 2168-6173Vydavateľské údaje: United States 01.06.2016Vydané v JAMA ophthalmology (01.06.2016)“…Published definitions of plus disease in retinopathy of prematurity (ROP) reference arterial tortuosity and venous dilation within the posterior pole based on…”
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S-nitrosohemoglobin deficiency: a mechanism for loss of physiological activity in banked blood
ISSN: 0027-8424Vydavateľské údaje: United States 23.10.2007Vydané v Proceedings of the National Academy of Sciences - PNAS (23.10.2007)“…RBCs distribute oxygen to tissues, but, paradoxically, blood transfusion does not always improve oxygen delivery and is associated with ischemic events. We…”
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Describing Retinopathy of Prematurity: Current Limitations and New Challenges
ISSN: 1549-4713, 1549-4713Vydavateľské údaje: United States 01.05.2019Vydané v Ophthalmology (Rochester, Minn.) (01.05.2019)Zistit podrobnosti o prístupe
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S-Nitrosylated hemoglobin predicts organ yield in neurologically-deceased human donors
ISSN: 2045-2322, 2045-2322Vydavateľské údaje: London Nature Publishing Group UK 22.04.2022Vydané v Scientific reports (22.04.2022)“…Current human donor care protocols following death by neurologic criteria (DNC) can stabilize macro-hemodynamic parameters but have minimal ability to preserve…”
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Single‐Contact, Four‐Terminal Microelectromechanical Relay for Efficient Digital Logic
ISSN: 2199-160X, 2199-160XVydavateľské údaje: Seoul John Wiley & Sons, Inc 01.01.2023Vydané v Advanced electronic materials (01.01.2023)“…Nano and microelectromechanical relays can be used in lieu of transistors to build digital integrated circuits that can operate with zero leakage current at…”
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Role of Nitric Oxide Carried by Hemoglobin in Cardiovascular Physiology: Developments on a Three-Gas Respiratory Cycle
ISSN: 1524-4571, 1524-4571Vydavateľské údaje: United States 03.01.2020Vydané v Circulation research (03.01.2020)“…A continuous supply of oxygen is essential for the survival of multicellular organisms. The understanding of how this supply is regulated in the…”
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Ranibizumab versus laser therapy for the treatment of very low birthweight infants with retinopathy of prematurity (RAINBOW): an open-label randomised controlled trial
ISSN: 0140-6736, 1474-547X, 1474-547XVydavateľské údaje: England Elsevier Ltd 26.10.2019Vydané v The Lancet (British edition) (26.10.2019)“…Despite increasing worldwide use of anti-vascular endothelial growth factor agents for treatment of retinopathy of prematurity (ROP), there are few data on…”
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S-nitrosylation therapy to improve oxygen delivery of banked blood
ISSN: 1091-6490, 1091-6490Vydavateľské údaje: United States 09.07.2013Vydané v Proceedings of the National Academy of Sciences - PNAS (09.07.2013)“…From the perspectives of disease transmission and sterility maintenance, the world's blood supplies are generally safe. However, in multiple clinical settings,…”
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Airway Thiol-NO Adducts as Determinants of Exhaled NO
ISSN: 2076-3921, 2076-3921Vydavateľské údaje: Switzerland MDPI AG 26.09.2021Vydané v Antioxidants (26.09.2021)“…Thiol-NO adducts such as S-nitrosoglutathione (GSNO) are endogenous bronchodilators in human airways. Decreased airway S-nitrosothiol concentrations are…”
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International Classification of Retinopathy of Prematurity, Third Edition
ISSN: 1549-4713, 1549-4713Vydavateľské údaje: United States 01.10.2021Vydané v Ophthalmology (Rochester, Minn.) (01.10.2021)“…The International Classification of Retinopathy of Prematurity is a consensus statement that creates a standard nomenclature for classification of retinopathy…”
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Hemoglobin S-nitrosylation plays an essential role in cardioprotection
ISSN: 0021-9738, 1558-8238, 1558-8238Vydavateľské údaje: United States American Society for Clinical Investigation 01.12.2016Vydané v The Journal of clinical investigation (01.12.2016)“…Homeostatic control of tissue oxygenation is achieved largely through changes in blood flow that are regulated by the classic physiological response of hypoxic…”
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Hemoglobin βCys93 is essential for cardiovascular function and integrated response to hypoxia
ISSN: 1091-6490, 1091-6490Vydavateľské údaje: United States 19.05.2015Vydané v Proceedings of the National Academy of Sciences - PNAS (19.05.2015)“…Oxygen delivery by Hb is essential for vertebrate life. Three amino acids in Hb are strictly conserved in all mammals and birds, but only two of those, a His…”
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An enzyme that selectively S-nitrosylates proteins to regulate insulin signaling
ISSN: 1097-4172, 1097-4172Vydavateľské údaje: United States 21.12.2023Vydané v Cell (21.12.2023)“…Acyl-coenzyme A (acyl-CoA) species are cofactors for numerous enzymes that acylate thousands of proteins. Here, we describe an enzyme that uses S-nitroso-CoA…”
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Can nitric oxide-based therapy prevent bronchopulmonary dysplasia?
ISSN: 1557-9840, 1557-9840Vydavateľské údaje: United States 01.09.2012Vydané v Clinics in perinatology (01.09.2012)“…A growing understanding of endogenous nitric oxide (NO) biology is helping to explain how and when exogenous NO may confer benefit or harm; this knowledge is…”
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Red Blood Cell-Mediated S-Nitrosohemoglobin-Dependent Vasodilation: Lessons Learned from a β-Globin Cys93 Knock-In Mouse
ISSN: 1557-7716, 1557-7716Vydavateľské údaje: United States 20.04.2021Vydané v Antioxidants & redox signaling (20.04.2021)“…Red blood cell (RBC)-mediated vasodilation plays an important role in oxygen delivery. This occurs through hemoglobin actions, at least in significant part, to…”
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Reducing acetylated tau is neuroprotective in brain injury
ISSN: 1097-4172, 1097-4172Vydavateľské údaje: United States 13.05.2021Vydané v Cell (13.05.2021)“…Traumatic brain injury (TBI) is the largest non-genetic, non-aging related risk factor for Alzheimer's disease (AD). We report here that TBI induces tau…”
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2-year outcomes of ranibizumab versus laser therapy for the treatment of very low birthweight infants with retinopathy of prematurity (RAINBOW extension study): prospective follow-up of an open label, randomised controlled trial
ISSN: 2352-4650, 2352-4650Vydavateľské údaje: 01.10.2021Vydané v The lancet child & adolescent health (01.10.2021)“…Intravitreal injection of vascular endothelial growth factor (VEGF) inhibitors is increasingly used to treat retinopathy of prematurity (ROP) in the absence of…”
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Urrets-Zavalia syndrome following goniotomy in a child
ISSN: 1091-8531, 1528-3933, 1528-3933Vydavateľské údaje: United States Mosby, Inc 01.06.2012Vydané v Journal of AAPOS (01.06.2012)“…Urrets-Zavalia syndrome is a surgical complication in which the pupil remains fixed and dilated after a procedure. It is believed to be caused by brief periods…”
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