Výsledky vyhľadávania - "Refsum, Helga"

Homocysteine, B Vitamins, and Cognitive Impairment Autor Smith, A David, Refsum, Helga

“…Moderately elevated plasma total homocysteine (tHcy) is a strong modifiable risk factor for vascular dementia and Alzheimer's disease. Prospectively, elevated…”
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Branched-chain amino acid metabolism, insulin sensitivity and liver fat response to exercise training in sedentary dysglycaemic and normoglycaemic men Autor Lee, Sindre, Gulseth, Hanne L., Langleite, Torgrim M., Norheim, Frode, Olsen, Thomas, Refsum, Helga, Jensen, Jørgen, Birkeland, Kåre I., Drevon, Christian A.

“…Aims/hypothesis Obesity and insulin resistance may be associated with elevated plasma concentration of branched-chain amino acids (BCAAs) and impaired BCAA…”
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Biomarkers of Nutrition for Development (BOND): Vitamin B-12 Review Autor Allen, Lindsay H, Miller, Joshua W, de Groot, Lisette, Rosenberg, Irwin H, Smith, A David, Refsum, Helga, Raiten, Daniel J

“…This report on vitamin B-12 (B12) is part of the Biomarkers of Nutrition for Development (BOND) Project, which provides state-of-the art information and advice…”
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Homocysteine and Dementia: An International Consensus Statement Autor Smith, A David, Refsum, Helga, Bottiglieri, Teodoro, Fenech, Michael, Hooshmand, Babak, McCaddon, Andrew, Miller, Joshua W, Rosenberg, Irwin H, Obeid, Rima

“…Identification of modifiable risk factors provides a crucial approach to the prevention of dementia. Nutritional or nutrient-dependent risk factors are…”
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Cognitive and clinical outcomes of homocysteine-lowering B-vitamin treatment in mild cognitive impairment: a randomized controlled trial Autor de Jager, Celeste A., Oulhaj, Abderrahim, Jacoby, Robin, Refsum, Helga, Smith, A. David

“…Background Homocysteine is a risk factor for Alzheimer's disease. In the first report on the VITACOG trial, we showed that homocysteine‐lowering treatment with…”
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Preventing Alzheimer's disease-related gray matter atrophy by B-vitamin treatment Autor Douaud, Gwenaëlle, Refsum, Helga, de Jager, Celeste A, Jacoby, Robin, Nichols, Thomas E, Smith, Stephen M, Smith, A David

“…Is it possible to prevent atrophy of key brain regions related to cognitive decline and Alzheimer's disease (AD)? One approach is to modify nongenetic risk…”
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Kynurenine Pathway Metabolites in Alzheimer's Disease Autor Giil, Lasse Melvaer, Midttun, Øivind, Refsum, Helga, Ulvik, Arve, Advani, Rajiv, Smith, A David, Ueland, Per Magne

“…Metabolites of tryptophan, produced via the kynurenine pathway (kynurenines), have been linked to Alzheimer's disease (AD) in small cohorts with conflicting…”
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Homocysteine-Lowering by B Vitamins Slows the Rate of Accelerated Brain Atrophy in Mild Cognitive Impairment: A Randomized Controlled Trial Autor Smith, A. David, Smith, Stephen M., de Jager, Celeste A., Whitbread, Philippa, Johnston, Carole, Agacinski, Grzegorz, Oulhaj, Abderrahim, Bradley, Kevin M., Jacoby, Robin, Refsum, Helga

“…An increased rate of brain atrophy is often observed in older subjects, in particular those who suffer from cognitive decline. Homocysteine is a risk factor…”
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Effects of dietary methionine and cysteine restriction on plasma biomarkers, serum fibroblast growth factor 21, and adipose tissue gene expression in women with overweight or obesity: a double-blind randomized controlled pilot study Autor Olsen, Thomas, Øvrebø, Bente, Haj-Yasein, Nadia, Lee, Sindre, Svendsen, Karianne, Hjorth, Marit, Bastani, Nasser E., Norheim, Frode, Drevon, Christian A., Refsum, Helga, Vinknes, Kathrine J.

“…Background Dietary restriction of methionine and cysteine is a well-described model that improves metabolic health in rodents. To investigate the translational…”
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Vitamin B12 concentrations in milk from Norwegian women during the six first months of lactation Autor Henjum, Sigrun, Manger, Mari, Hampel, Daniela, Brantsæter, Anne Lise, Shahab-Ferdows, Setareh, Bastani, Nasser E, Strand, Tor A, Refsum, Helga, Allen, Lindsay H

“…Human milk vitamin B12 (B12) concentrations depend on maternal status and intake; only few data are available in high-income countries. We assessed human milk…”
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Concerning the debate about homocysteine, B vitamins, and dementia Autor Miller, Joshua W, McCaddon, Andrew, Yu, Jin-Tai, Hooshmand, Babak, Refsum, Helga, Smith, A David

“…It is important to identify modifiable risk factors for dementia and to introduce policies to implement their modification. The Lancet Commission on Dementia…”
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The kynurenine pathway and cognitive performance in community-dwelling older adults. The Hordaland Health Study Autor Solvang, Stein-Erik Hafstad, Nordrehaug, Jan Erik, Tell, Grethe S., Nygård, Ottar, McCann, Adrian, Ueland, Per Magne, Midttun, Øivind, Meyer, Klaus, Vedeler, Christian A., Aarsland, Dag, Refsum, Helga, Smith, A. David, Giil, Lasse Melvaer

“…•Tryptophan and kynurenines are related to inflammation and may be neuroactive.•Experimental studies indicates a role for the rate limiting enzyme IDO in…”
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Uptake and release of amino acids in the fetal-placental unit in human pregnancies Autor Holm, Maia Blomhoff, Bastani, Nasser Ezzatkhah, Holme, Ane Moe, Zucknick, Manuela, Jansson, Thomas, Refsum, Helga, Mørkrid, Lars, Blomhoff, Rune, Henriksen, Tore, Michelsen, Trond Melbye

“…The current concepts of human fetal-placental amino acid exchange and metabolism are mainly based on animal-, in vitro- and ex vivo models. We aimed to…”
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Association of Cysteine with Obesity, Inflammatory Cytokines and Insulin Resistance in Hispanic Children and Adolescents Autor Elshorbagy, Amany K, Valdivia-Garcia, Maria, Refsum, Helga, Butte, Nancy, Catapano, Alberico

“…Plasma total cysteine (tCys) independently relates to fat mass in adults. Dietary cyst(e)ine promotes adiposity and decreases glucose tolerance in some rodent…”
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Maternal Folate Intake during Pregnancy and Childhood Asthma in a Population-based Cohort Autor Parr, Christine L., Magnus, Maria C., Karlstad, Øystein, Haugen, Margaretha, Refsum, Helga, Ueland, Per M., McCann, Adrian, Nafstad, Per, Håberg, Siri E., Nystad, Wenche, London, Stephanie J.

“…A potential adverse effect of high folate intake during pregnancy on children's asthma development remains controversial. To prospectively investigate folate…”
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Acute effects of oral mesna administration on the full amino acid profile and 3-methylhistidine: secondary results from the CYLOB dose-finding study Autor Olsen, Thomas, Elshorbagy, Amany, Stolt, Emma, Åsberg, Anders, Zaré, Hasse K., Bastani, Nasser E., Refsum, Helga, Retterstøl, Kjetil, Vinknes, Kathrine J.

“…Plasma total cysteine (tCys) is strongly associated with fat mass in humans. Mesna lowers plasma tCys in a dose-dependent manner, but it is not known whether…”
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Dietary sulfur amino acid restriction in humans with overweight and obesity: a translational randomized controlled trial Autor Olsen, Thomas, Stolt, Emma, Øvrebø, Bente, Elshorbagy, Amany, Tore, Elena C., Lee-Ødegård, Sindre, Troensegaard, Hannibal, Johannessen, Hanna, Doeland, Beate, Vo, Anna A. D., Dahl, Anja F., Svendsen, Karianne, Thoresen, Magne, Refsum, Helga, Rising, Russell, Barvíková, Kristýna, van Greevenbroek, Marleen, Kožich, Viktor, Retterstøl, Kjetil, Vinknes, Kathrine J.

“…Background Dietary sulfur amino acid restriction (SAAR) improves metabolic health in animals. In this study, we investigated the effect of dietary SAAR on body…”
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Cobalamin and folate status predicts mental development scores in North Indian children 12-18 mo of age Autor Strand, Tor A, Taneja, Sunita, Ueland, Per M, Refsum, Helga, Bahl, Rajiv, Schneede, Joern, Sommerfelt, Halvor, Bhandari, Nita

“…Micronutrient deficiencies can affect cognitive function. Many young children in low- and middle-income countries have inadequate cobalamin (vitamin B-12)…”
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Sulfur amino acid restriction, energy metabolism and obesity: a study protocol of an 8-week randomized controlled dietary intervention with whole foods and amino acid supplements Autor Stolt, Emma, Olsen, Thomas, Elshorbagy, Amany, Kožich, Viktor, van Greevenbroek, Marleen, Øvrebø, Bente, Thoresen, Magne, Refsum, Helga, Retterstøl, Kjetil, Vinknes, Kathrine J.

“…Background Dietary sulfur amino acid (SAA) restriction is an established animal model for increasing lifespan and improving metabolic health. Data from human…”
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Vitamin B12 and Folic Acid Improve Gross Motor and Problem-Solving Skills in Young North Indian Children: A Randomized Placebo-Controlled Trial Autor Kvestad, Ingrid, Taneja, Sunita, Kumar, Tivendra, Hysing, Mari, Refsum, Helga, Yajnik, Chittaranjan S., Bhandari, Nita, Strand, Tor A.

“…Deficiencies of vitamin B12 and folate are associated with delayed development and neurological manifestations. The objective of this study was to measure the…”
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