Suchergebnisse - "Ragab, Mohab"
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Uncovering the relationship between gut microbial dysbiosis, metabolomics, and dietary intake in type 2 diabetes mellitus and in healthy volunteers: a multi-omics analysis
ISSN: 2045-2322, 2045-2322Veröffentlicht: London Nature Publishing Group UK 20.10.2023Veröffentlicht in Scientific reports (20.10.2023)“… Type 2 Diabetes Mellitus has reached epidemic levels globally, and several studies have confirmed a link between gut microbial dysbiosis and aberrant glucose …”
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Azathioprine promotes intestinal epithelial cell differentiation into Paneth cells and alleviates ileal Crohn’s disease severity
ISSN: 2045-2322, 2045-2322Veröffentlicht: London Nature Publishing Group UK 05.06.2024Veröffentlicht in Scientific reports (05.06.2024)“… Paneth cells (PCs), a subset of intestinal epithelial cells (IECs) found at the base of small intestinal crypts, play an essential role in maintaining …”
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Vasoactive intestinal peptide promotes secretory differentiation and mitigates radiation-induced intestinal injury
ISSN: 1757-6512, 1757-6512Veröffentlicht: London BioMed Central 08.10.2024Veröffentlicht in Stem cell research & therapy (08.10.2024)“… Background Vasoactive intestinal peptide (VIP) is a neuronal peptide with prominent distribution along the enteric nervous system. While effects of VIP on …”
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Metabolic and Lipidomic Markers Differentiate COVID-19 From Non-Hospitalized and Other Intensive Care Patients
ISSN: 2296-889X, 2296-889XVeröffentlicht: Switzerland Frontiers Media S.A 02.12.2021Veröffentlicht in Frontiers in molecular biosciences (02.12.2021)“… Coronavirus disease 2019 (COVID-19) is a viral infection affecting multiple organ systems of great significance for metabolic processes. Thus, there is …”
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IL-2-Agonist-Induced IFN-γ Exacerbates Systemic Anaphylaxis in Food Allergen-Sensitized Mice
ISSN: 1664-3224, 1664-3224Veröffentlicht: Switzerland Frontiers Media S.A 11.12.2020Veröffentlicht in Frontiers in immunology (11.12.2020)“… Food allergies are common, costly and potentially life-threatening disorders. They are driven by Th2, but inhibited by Th1 reactions. There is also evidence …”
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Purification and Functional Characterization of the Chloroform/Methanol-Soluble Protein 3 (CM3) From Triticum aestivum in Drosophila melanogaster
ISSN: 2296-861X, 2296-861XVeröffentlicht: Switzerland Frontiers Media S.A 23.12.2020Veröffentlicht in Frontiers in nutrition (Lausanne) (23.12.2020)“… Non-celiac wheat sensitivity (NCWS) has been proposed to be an independent disease entity that is characterized by intestinal (e.g., abdominal pain, …”
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The Therapeutic Potential of Farm Dust Extracts in a Mouse Model of Eosinophilic Inflammation
ISSN: 0105-4538, 1398-9995, 1398-9995Veröffentlicht: Denmark 22.10.2025Veröffentlicht in Allergy (Copenhagen) (22.10.2025)“… Asthma affects over 355 million people globally and poses a major healthcare burden. While corticosteroids remain a cornerstone of treatment, their side …”
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Prognostic Value of SOX2 and NANOG Expression in Recurrent Oral Squamous Cell Carcinoma
ISSN: 2072-6694, 2072-6694Veröffentlicht: Switzerland MDPI AG 31.03.2025Veröffentlicht in Cancers (31.03.2025)“… Background: Recurrent oral squamous cell carcinoma (re-OSCC) poses a serious therapeutic challenge and is linked to poor survival outcomes. SOX2 and NANOG, key …”
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Epithelial genetic muscarinic receptor 3 ablation induces sex-specific modulation of colonic intestinal progenitor cells and response to intestinal injury
ISSN: 1873-9946, 1876-4479, 1876-4479Veröffentlicht: UK Oxford University Press 04.06.2025Veröffentlicht in Journal of Crohn's and colitis (04.06.2025)“… Abstract Background & Aims Epithelial muscarinic acetylcholine receptor subtype 3 (M3R) signaling modulates intestinal stem and progenitor cell function, yet …”
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Loss of Mucosal p32/gC1qR/HABP1 Triggers Energy Deficiency and Impairs Goblet Cell Differentiation in Ulcerative Colitis
ISSN: 2352-345X, 2352-345XVeröffentlicht: United States Elsevier Inc 01.01.2021Veröffentlicht in Cellular and molecular gastroenterology and hepatology (01.01.2021)“… Cell differentiation in the colonic crypt is driven by a metabolic switch from glycolysis to mitochondrial oxidation. Mitochondrial and goblet cell dysfunction …”
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Colorectal Cancer Progression Is Potently Reduced by a Glucose-Free, High-Protein Diet: Comparison to Anti-EGFR Therapy
ISSN: 2072-6694, 2072-6694Veröffentlicht: Basel MDPI AG 19.11.2021Veröffentlicht in Cancers (19.11.2021)“… To enable rapid proliferation, colorectal tumor cells up-regulate epidermal growth factor receptor (EGFR) signaling and aerobic glycolysis, resulting in …”
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Loss of Mucosal p32/gC1qR/HABP1 Triggers Energy Deficiency and Impairs Goblet Cell Differentiation in Ulcerative ColitisSummary
ISSN: 2352-345X, 2352-345XVeröffentlicht: Elsevier 01.01.2021Veröffentlicht in Cellular and molecular gastroenterology and hepatology (01.01.2021)“… Background & Aims: Cell differentiation in the colonic crypt is driven by a metabolic switch from glycolysis to mitochondrial oxidation. Mitochondrial and …”
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Colorectal cancer progression is potently reduced by a glucose-free, high-protein diet: comparison to anti-EGFR therapy
ISSN: 2692-8205, 2692-8205Veröffentlicht: Cold Spring Harbor Cold Spring Harbor Laboratory Press 16.06.2021Veröffentlicht in bioRxiv (16.06.2021)“… Background & Aims: To enable rapid proliferation, colorectal tumor cells up-regulate epidermal growth factor receptor (EGFR) signaling and perform high level …”
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Loss of p32 triggers energy deficiency and impairs goblet cell differentiation in ulcerative colitis
ISSN: 2692-8205, 2692-8205Veröffentlicht: Cold Spring Harbor Cold Spring Harbor Laboratory Press 10.12.2020Veröffentlicht in bioRxiv (10.12.2020)“… Abstract Cell differentiation in the colonic crypt is driven by a metabolic switch from glycolysis to mitochondrial oxidation. Mitochondrial and goblet cell …”
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