Suchergebnisse - "RNA"

Single-Cell RNA Sequencing Reveals Expanded Clones of Islet Antigen-Reactive CD4 + T Cells in Peripheral Blood of Subjects with Type 1 Diabetes von Cerosaletti, Karen, Barahmand-Pour-Whitman, Fariba, Yang, Junbao, DeBerg, Hannah A, Dufort, Matthew J, Murray, Sara A, Israelsson, Elisabeth, Speake, Cate, Gersuk, Vivian H, Eddy, James A, Reijonen, Helena, Greenbaum, Carla J, Kwok, William W, Wambre, Erik, Prlic, Martin, Gottardo, Raphael, Nepom, Gerald T, Linsley, Peter S

“… ) subjects is unclear, partly because similar cells are also found in healthy control (HC) subjects. We hypothesized that key disease-associated cells would show evidence …”
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The clinical utility and diagnostic implementation of human subject cell transdifferentiation followed by RNA sequencing von Li, Shenglan, Zhao, Sen, Sinson, Jefferson C, Bajic, Aleksandar, Rosenfeld, Jill A, Neeley, Matthew B, Pena, Mezthly, Worley, Kim C, Burrage, Lindsay C, Weisz-Hubshman, Monika, Ketkar, Shamika, Craigen, William J, Clark, Gary D, Lalani, Seema, Bacino, Carlos A, Machol, Keren, Chao, Hsiao-Tuan, Potocki, Lorraine, Emrick, Lisa, Sheppard, Jennifer, Nguyen, My T T, Khoramnia, Anahita, Hernandez, Paula Patricia, Nagamani, Sandesh Cs, Liu, Zhandong, Eng, Christine M, Lee, Brendan, Liu, Pengfei

“… RNA sequencing (RNA-seq) has recently been used in translational research settings to facilitate diagnoses of Mendelian disorders …”
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Benchmarking methods for detecting differential states between conditions from multi-subject single-cell RNA-seq data von Junttila, Sini, Smolander, Johannes, Elo, Laura L

“… Abstract Single-cell RNA-sequencing (scRNA-seq) enables researchers to quantify transcriptomes of thousands of cells simultaneously and study transcriptomic changes between cells …”
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A Plasma Circular RNA Profile Differentiates Subjects with Alzheimer’s Disease and Mild Cognitive Impairment from Healthy Controls von Piscopo, Paola, Manzini, Valeria, Rivabene, Roberto, Crestini, Alessio, Le Pera, Loredana, Pizzi, Elisabetta, Veroni, Caterina, Talarico, Giuseppina, Peconi, Martina, Castellano, Anna Elisa, D’Alessio, Carmelo, Bruno, Giuseppe, Corbo, Massimo, Vanacore, Nicola, Lacorte, Eleonora

“… These tests are rather complex and invasive and not easily applicable to clinical practice. Circulating non-coding RNAs, which are inherently stable and easy to manage, have been reported as promising biomarkers for central nervous system conditions …”
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Antibody Response to the BNT162b2 mRNA COVID-19 Vaccine in Subjects with Prior SARS-CoV-2 Infection von Gobbi, Federico, Buonfrate, Dora, Moro, Lucia, Rodari, Paola, Piubelli, Chiara, Caldrer, Sara, Riccetti, Silvia, Sinigaglia, Alessandro, Barzon, Luisa

“… subjects without a previous infection. The vaccine was well tolerated by both groups, with no significant difference in the frequency of vaccine-associated side effects …”
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Total Extracellular Small RNA Profiles from Plasma, Saliva, and Urine of Healthy Subjects von Yeri, Ashish, Courtright, Amanda, Reiman, Rebecca, Carlson, Elizabeth, Beecroft, Taylor, Janss, Alex, Siniard, Ashley, Richholt, Ryan, Balak, Chris, Rozowsky, Joel, Kitchen, Robert, Hutchins, Elizabeth, Winarta, Joseph, McCoy, Roger, Anastasi, Matthew, Kim, Seungchan, Huentelman, Matthew, Van Keuren-Jensen, Kendall

“… There are few datasets describing baseline expression levels for total cell-free circulating RNA from healthy control subjects …”
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EDClust: an EM-MM hybrid method for cell clustering in multiple-subject single-cell RNA sequencing von Wei, Xin, Li, Ziyi, Ji, Hongkai, Wu, Hao

“… Single-cell RNA sequencing (scRNA-seq) has revolutionized biological research by enabling the measurement of transcriptomic profiles at the single-cell level …”
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Correction: iDESC: identifying differential expression in single-cell RNA sequencing data with multiple subjects von Liu, Yunqing, Zhao, Jiayi, Adams, Taylor S., Wang, Ningya, Schupp, Jonas C., Wu, Weimiao, McDonough, John E., Chupp, Geoffrey L., Kaminski, Naftali, Wang, Zuoheng, Yan, Xiting

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A Modified Ligature‐Induced Peri‐Implantitis Murine Model and RNA Sequencing Analysis Compared With Human Subjects von Tong, Zi‐an, Chen, Long, Shen, Ling, Lu, Yi‐fan, Zhang, Jian‐wei, Qi, Ya‐dong, Qian, Yin‐jie, Bao, Si‐qi, Chen, Wei, Si, Mi‐si

“… RNA sequencing was performed to determine the transcriptomic profiles of peri‐implant tissues from mice, patients with peri …”
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EDClust: an EM–MM hybrid method for cell clustering in multiple-subject single-cell RNA sequencing von Wei, Xin, Li, Ziyi, Ji, Hongkai, Wu, Hao

“… Abstract Motivation Single-cell RNA sequencing (scRNA-seq) has revolutionized biological research by enabling the measurement of transcriptomic profiles at the single-cell level …”
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Differential gene expression analysis for multi-subject single-cell RNA-sequencing studies with aggregateBioVar von Thurman, Andrew L, Ratcliff, Jason A, Chimenti, Michael S, Pezzulo, Alejandro A

“… Abstract Motivation Single-cell RNA-sequencing (scRNA-seq) provides more granular biological information than bulk RNA-sequencing …”
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MuDCoD: multi-subject community detection in personalized dynamic gene networks from single-cell RNA sequencing von Şapcı, Ali Osman Berk, Lu, Shan, Yan, Shuchen, Ay, Ferhat, Tastan, Oznur, Keleş, Sündüz

“… Abstract Motivation With the wide availability of single-cell RNA-seq (scRNA-seq) technology, population-scale scRNA-seq datasets across multiple individuals and time points are emerging …”
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iDESC: identifying differential expression in single-cell RNA sequencing data with multiple subjects von Liu, Yunqing, Zhao, Jiayi, Adams, Taylor S., Wang, Ningya, Schupp, Jonas C., Wu, Weimiao, McDonough, John E., Chupp, Geoffrey L., Kaminski, Naftali, Wang, Zuoheng, Yan, Xiting

“… Background Single-cell RNA sequencing (scRNA-seq) technology has enabled assessment of transcriptome-wide changes at single-cell resolution …”
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HTLV-1 viral RNA is detected rarely in plasma of HTLV-1 infected subjects von Demontis, Maria Antonietta, Sadiq, Maaz Tahir, Golz, Simon, Taylor, Graham P.

“… ‐1 RNA in plasma and assess its potential value in diagnosis and prognosis. RNA from 1 ml of plasma from 65 subjects infected with HTLV …”
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RNA Hypomethylation and Unchanged DNA Methylation Levels in the Cortex of ApoE4 Carriers and Alzheimer's Disease Subjects von Shen, Wei-Bin, Yang, James Jiao, Yang, Peixin

“… Epigenetic modifications are involved in AD pathology. However, it is unclear whether DNA/RNA methylation plays a role in AD pathology, and dysregulation of DNA/RNA methylation occurs in ApoE4 carriers …”
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Longevity‐related molecular pathways are subject to midlife “switch” in humans von Timmons, James A., Volmar, Claude‐Henry, Crossland, Hannah, Phillips, Bethan E., Sood, Sanjana, Janczura, Karolina J., Törmäkangas, Timo, Kujala, Urho M., Kraus, William E., Atherton, Philip J., Wahlestedt, Claes

“… Applying our novel RNA method to quantify tissue coding and long noncoding RNA (lncRNA), we identified ~800 transcripts tracking with age …”
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MicroRNA Expression Is Down-Regulated and Reorganized in Prefrontal Cortex of Depressed Suicide Subjects von Smalheiser, Neil R., Lugli, Giovanni, Rizavi, Hooriyah S., Torvik, Vetle I., Turecki, Gustavo, Dwivedi, Yogesh

“… Recent studies suggest that alterations in expression of genes, including those which regulate neural and structural plasticity, may be crucial in the pathogenesis of depression. MicroRNAs (miRNAs …”
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SCCPMD: Probability matrix decomposition method subject to corrected similarity constraints for inferring long non-coding RNA–disease associations von Lin, Lieqing, Chen, Ruibin, Zhu, Yinting, Xie, Weijie, Jing, Huaiguo, Chen, Langcheng, Zou, Minqing

“… Accumulating evidence has demonstrated various associations of long non-coding RNAs (lncRNAs …”
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Integrating mRNA and miRNA Weighted Gene Co-Expression Networks with eQTLs in the Nucleus Accumbens of Subjects with Alcohol Dependence von Mamdani, Mohammed, Williamson, Vernell, McMichael, Gowon O., Blevins, Tana, Aliev, Fazil, Adkins, Amy, Hack, Laura, Bigdeli, Tim, D. van der Vaart, Andrew, Web, Bradley Todd, Bacanu, Silviu-Alin, Kalsi, Gursharan, Kendler, Kenneth S., Miles, Michael F., Dick, Danielle, Riley, Brien P., Dumur, Catherine, Vladimirov, Vladimir I.

“… ) on genome-wide mRNA and microRNA (miRNA) expression in Nucleus Accumbens (NAc) of subjects with alcohol dependence (AD; N = 18 …”
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Bulk tissue cell type deconvolution with multi-subject single-cell expression reference von Wang, Xuran, Park, Jihwan, Susztak, Katalin, Zhang, Nancy R., Li, Mingyao

“… We present MuSiC, a method that utilizes cell-type specific gene expression from single-cell RNA sequencing (RNA-seq …”
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