Search Results - "RBD"

REM sleep behavior disorder (RBD) by Hu, Michele T.

“… RBD patients one decade later, RBD has emerged in recent years as one of the most promising markers of prodromal Parkinson's (References 2, 3…”
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Neuropsychological assessment in idiopathic REM sleep behavior disorder (RBD): does the idiopathic form of RBD really exist? by Ferini-Strambi, L, Di Gioia, M R, Castronovo, V, Oldani, A, Zucconi, M, Cappa, S F

“…). The authors studied 17 consecutive patients with idiopathic RBD vs 17 age- and education-matched control subjects…”
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COVID-19: S-Peptide RBD 484–508 Induces IFN-γ T-Cell Response in Naïve-to-Infection and Unvaccinated Subjects with Close Contact with SARS-CoV-2-Positive Patients by Murdocca, Michela, Citro, Gennaro, Centanini, Eleonora, Giannini, Rosalinda, Latini, Andrea, Centofanti, Federica, Piano Mortari, Eva, Cocciadiferro, Dario, Novelli, Antonio, Bernardini, Sergio, Novelli, Giuseppe, Sangiuolo, Federica

“… In this study, we report on 28 naïve-to-SARS-Cov-2-infection and unvaccinated subjects, having reported a close and prolonged contact with COVID-19-positive patients…”
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Prevalent, protective, and convergent IgG recognition of SARS-CoV-2 non-RBD spike epitopes by Voss, William N, Hou, Yixuan J, Johnson, Nicole V, Delidakis, George, Kim, Jin Eyun, Javanmardi, Kamyab, Horton, Andrew P, Bartzoka, Foteini, Paresi, Chelsea J, Tanno, Yuri, Chou, Chia-Wei, Abbasi, Shawn A, Pickens, Whitney, George, Katia, Boutz, Daniel R, Towers, Dalton M, McDaniel, Jonathan R, Billick, Daniel, Goike, Jule, Rowe, Lori, Batra, Dhwani, Pohl, Jan, Lee, Justin, Gangappa, Shivaprakash, Sambhara, Suryaprakash, Gadush, Michelle, Wang, Nianshuang, Person, Maria D, Iverson, Brent L, Gollihar, Jimmy D, Dye, John, Herbert, Andrew, Finkelstein, Ilya J, Baric, Ralph S, McLellan, Jason S, Georgiou, George, Lavinder, Jason J, Ippolito, Gregory C

“…%) against epitopes residing outside the receptor-binding domain (RBD). In one subject, just four IgG lineages accounted for 93.5…”
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α-Synuclein BAC transgenic mice exhibit RBD-like behaviour and hyposmia: a prodromal Parkinson's disease model by Taguchi, Tomoyuki, Ikuno, Masashi, Hondo, Mari, Parajuli, Laxmi Kumar, Taguchi, Katsutoshi, Ueda, Jun, Sawamura, Masanori, Okuda, Shinya, Nakanishi, Etsuro, Hara, Junko, Uemura, Norihito, Hatanaka, Yusuke, Ayaki, Takashi, Matsuzawa, Shuichi, Tanaka, Masaki, El-Agnaf, Omar M A, Koike, Masato, Yanagisawa, Masashi, Uemura, Maiko T, Yamakado, Hodaka, Takahashi, Ryosuke

“… As subjects with α-synuclein gene (SNCA) multiplication as well as point mutations develop familial Parkinson's disease and a genome-wide association study in Parkinson's disease has identified SNCA as a risk gene for Parkinson's disease…”
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Mosaic RBD nanoparticles protect against challenge by diverse sarbecoviruses in animal models by Cohen, Alexander A, van Doremalen, Neeltje, Greaney, Allison J, Andersen, Hanne, Sharma, Ankur, Starr, Tyler N, Keeffe, Jennifer R, Fan, Chengcheng, Schulz, Jonathan E, Gnanapragasam, Priyanthi N P, Kakutani, Leesa M, West, Jr, Anthony P, Saturday, Greg, Lee, Yu E, Gao, Han, Jette, Claudia A, Lewis, Mark G, Tan, Tiong K, Townsend, Alain R, Bloom, Jesse D, Munster, Vincent J, Bjorkman, Pamela J

“…) threatening global health, we designed mosaic nanoparticles that present randomly arranged sarbecovirus spike receptor-binding domains (RBDs…”
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Immunogenicity and safety in pigs of PHH-1V, a SARS-CoV-2 RBD fusion heterodimer vaccine candidate by Moros, Alexandra, Prenafeta, Antoni, Barreiro, Antonio, Perozo, Eva, Fernández, Alex, Cañete, Manuel, González, Luis, Garriga, Carme, Pradenas, Edwards, Marfil, Silvia, Blanco, Julià, Cebollada Rica, Paula, Sisteré-Oró, Marta, Meyerhans, Andreas, Prat Cabañas, Teresa, March, Ricard, Ferrer, Laura

“… We have developed an adjuvanted vaccine candidate, PHH-1V, based on a protein comprising the receptor binding domain (RBD…”
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Brain imaging findings in idiopathic REM sleep behavior disorder (RBD) – A systematic review on potential biomarkers for neurodegeneration by Heller, Julia, Brcina, Nikolina, Dogan, Imis, Holtbernd, Florian, Romanzetti, Sandro, Schulz, Jörg B., Schiefer, Johannes, Reetz, Kathrin

“… Over the past years, a growing number of studies have sought to establish reliable neuroimaging markers to detect neurodegenerative brain changes in RBD subjects at the earliest possible stage…”
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Dissection of Antibody Responses of Gam-COVID-Vac-Vaccinated Subjects Suggests Involvement of Epitopes Outside RBD in SARS-CoV-2 Neutralization by Byazrova, Maria, Gattinger, Pia, Astakhova, Ekaterina, Hofer, Gerhard, Khaitov, Musa, Filatov, Alexander, Valenta, Rudolf

“… naïve and 10 coronavirus disease 2019 (COVID-19) convalescent subjects was obtained before and after two immunizations with Gam-COVID-Vac…”
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RBD-specific antibody responses after two doses of BBIBP-CorV (Sinopharm, Beijing CNBG) vaccine by Ferenci, Tamás, Sarkadi, Balázs

“… Methods RBD-specific antibody titres, as a rapidly available and highly predictive surrogate marker, were measured after two doses of the BBIBP-CorV vaccine in 450 subjects…”
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Vaccine based on folded RBD‐PreS fusion protein with potential to induce sterilizing immunity to SARS‐CoV‐2 variants by Gattinger, Pia, Kratzer, Bernhard, Tulaeva, Inna, Niespodziana, Katarzyna, Ohradanova‐Repic, Anna, Gebetsberger, Laura, Borochova, Kristina, Garner‐Spitzer, Erika, Trapin, Doris, Hofer, Gerhard, Keller, Walter, Baumgartner, Isabella, Tancevski, Ivan, Khaitov, Musa, Karaulov, Alexander, Stockinger, Hannes, Wiedermann, Ursula, Pickl, Winfried F., Valenta, Rudolf

“… of concern.PreS‐RBD‐specific antibodies of the immunized subject more potently inhibit the interaction of RBD with angiotensin converting enzyme 2 (ACE2), and their virus…”
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Reduced Intracortical Facilitation to TMS in Both Isolated REM Sleep Behavior Disorder (RBD) and Early Parkinson’s Disease with RBD by Lanza, Giuseppe, Cosentino, Filomena Irene Ilaria, Lanuzza, Bartolo, Tripodi, Mariangela, Aricò, Debora, Figorilli, Michela, Puligheddu, Monica, Fisicaro, Francesco, Bella, Rita, Ferri, Raffaele, Pennisi, Manuela

“…) measure largely mediated by glutamatergic neurotransmission, was observed in subjects affected by isolated REM sleep behavior disorder (iRBD…”
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Analytical and clinical performances of a SARS-CoV-2 S-RBD IgG assay: comparison with neutralization titers by Padoan, Andrea, Bonfante, Francesco, Cosma, Chiara, Di Chiara, Costanza, Sciacovelli, Laura, Pagliari, Matteo, Bortolami, Alessio, Costenaro, Paola, Musso, Giulia, Basso, Daniela, Giaquinto, Carlo, Plebani, Mario

“… We investigated the analytical and clinical performances of a SARS-CoV-2 RBD IgG assay, automated on a high throughput platform, and the correlation of the antibodies (Ab…”
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Evaluation of Anti-SARS-Cov-2 S-RBD IgG Antibodies after COVID-19 mRNA BNT162b2 Vaccine by Lo Sasso, Bruna, Giglio, Rosaria Vincenza, Vidali, Matteo, Scazzone, Concetta, Bivona, Giulia, Gambino, Caterina Maria, Ciaccio, Anna Maria, Agnello, Luisa, Ciaccio, Marcello

“…: Anti S-RBD IgG levels were lower in subjects with previous infection than vaccinated subjects, with or without previous infection (p < 0.001…”
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Olfactory dysfunction predicts early transition to a Lewy body disease in idiopathic RBD by Mahlknecht, Philipp, Iranzo, Alex, Högl, Birgit, Frauscher, Birgit, Müller, Christoph, Santamaría, Joan, Tolosa, Eduardo, Serradell, Monica, Mitterling, Thomas, Gschliesser, Viola, Goebel, Georg, Brugger, Florian, Scherfler, Christoph, Poewe, Werner, Seppi, Klaus

“…The aim of the present study was to determine the predictive value of olfactory dysfunction for the early development of a synuclein-mediated neurodegenerative disease in subjects with idiopathic REM…”
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COVID-19: S-Peptide RBD [sub.484–508] Induces IFN-γ T-Cell Response in Naïve-to-Infection and Unvaccinated Subjects with Close Contact with SARS-CoV-2-Positive Patients by Murdocca, Michela, Citro, Gennaro, Centanini, Eleonora, Giannini, Rosalinda, Latini, Andrea, Centofanti, Federica, Piano Mortari, Eva, Cocciadiferro, Dario, Novelli, Antonio, Bernardini, Sergio, Novelli, Giuseppe, Sangiuolo, Federica

“… In this study, we report on 28 naïve-to-SARS-Cov-2-infection and unvaccinated subjects, having reported a close and prolonged contact with COVID-19-positive patients…”
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Anti-SARS-CoV-2 RBD IgG responses in convalescent versus naïve BNT162b2 vaccine recipients by Azzi, Lorenzo, Focosi, Daniele, Dentali, Francesco, Baj, Andreina, Maggi, Fabrizio

“… and naïve subjects with the same schedule.•Most health systems are suffering shortages of vaccines…”
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High titre neutralizing antibodies in response to SARS–CoV–2 infection require RBD–specific CD4 T cells that include proliferative memory cells by Phetsouphanh, Chansavath, Khoo, Weng Hua, Jackson, Katherine, Klemm, Vera, Howe, Annett, Aggarwal, Anupriya, Akerman, Anouschka, Milogiannakis, Vanessa, Stella, Alberto Ospina, Rouet, Romain, Schofield, Peter, Faulks, Megan L., Law, Hannah, Danwilai, Thidarat, Starr, Mitchell, Munier, C. Mee Ling, Christ, Daniel, Singh, Mandeep, Croucher, Peter I., Brilot-Turville, Fabienne, Turville, Stuart, Phan, Tri Giang, Dore, Gregory J., Darley, David, Cunningham, Philip, Matthews, Gail V., Kelleher, Anthony D., Zaunders, John J.

“…)-specific memory CD4 T cells. These low antibody subjects had other, non-RBD, spike-specific CD4 T cells, but with more…”
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Robust specific RBD responses and neutralizing antibodies after ChAdOx1 nCoV-19 and CoronaVac vaccination in SARS-CoV-2– seropositive individuals by Fernandes, Edgar Ruz, Taminato, Monica, de Souza Apostolico, Juliana, Gabrielonni, Maria Cristina, Lunardelli, Victoria Alves Santos, Maricato, Juliana Terzi, Andersen, Monica Levy, Tufik, Sergio, Rosa, Daniela Santoro

“…The pandemic unleashed by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected more than 500 million people worldwide and caused more than…”
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A randomized, double-blind phase I clinical trial of two recombinant dimeric RBD COVID-19 vaccine candidates: Safety, reactogenicity and immunogenicity by Pérez-Rodríguez, Sonia, de la Caridad Rodríguez-González, Meiby, Ochoa-Azze, Rolando, Climent-Ruiz, Yanet, Alberto González-Delgado, Carlos, Paredes-Moreno, Beatriz, Valenzuela-Silva, Carmen, Rodríguez-Noda, Laura, Perez-Nicado, Rocmira, González-Mugica, Raúl, Martínez-Pérez, Marisel, Sánchez-Ramírez, Belinda, Hernández-García, Tays, Díaz-Machado, Alina, Tamayo-Rodríguez, Maura, Martín-Trujillo, Alis, Rubino-Moreno, Jorman, Suárez-Batista, Anamary, Dubed-Echevarría, Marta, Teresa Pérez-Guevara, María, Amoroto-Roig, Mayté, Chappi-Estévez, Yanet, Bergado-Báez, Gretchen, Pi-Estopiñán, Franciscary, Chen, Guang-Wu, Valdés-Balbín, Yury, García-Rivera, Dagmar, Verez-Bencomo, Vicente

“… Sixty Cuban volunteers aged 19–59 years were randomized into three groups (20 subjects each): 1) FINLAY-FR-1 (50 µg d-RBD plus outer membrane vesicles from N…”
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