Suchergebnisse - "Quintana, Francisco"
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1
The Role of Astrocytes in CNS Inflammation
ISSN: 1471-4906, 1471-4981, 1471-4981Veröffentlicht: England Elsevier Ltd 01.09.2020Veröffentlicht in Trends in immunology (01.09.2020)“… Astrocytes are the most abundant cell type in the central nervous system (CNS), performing complex functions in health and disease. It is now clear that …”
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The aryl hydrocarbon receptor: an environmental sensor integrating immune responses in health and disease
ISSN: 1474-1733, 1474-1741, 1474-1741Veröffentlicht: England Nature Publishing Group 01.03.2019Veröffentlicht in Nature reviews. Immunology (01.03.2019)“… The environment, diet, microbiota and body's metabolism shape complex biological processes in health and disease. However, our understanding of the molecular …”
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Astrocyte Crosstalk in CNS Inflammation
ISSN: 1097-4199, 1097-4199Veröffentlicht: United States 25.11.2020Veröffentlicht in Neuron (Cambridge, Mass.) (25.11.2020)“… Astrocytes control multiple processes in the nervous system in health and disease. It is now clear that specific astrocyte subsets or activation states are …”
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Regulation of the Immune Response by the Aryl Hydrocarbon Receptor
ISSN: 1097-4180, 1097-4180Veröffentlicht: United States 16.01.2018Veröffentlicht in Immunity (Cambridge, Mass.) (16.01.2018)“… The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that is activated by small molecules provided by the diet, microorganisms, …”
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Microglia and Central Nervous System-Associated Macrophages-From Origin to Disease Modulation
ISSN: 1545-3278, 1545-3278Veröffentlicht: United States 26.04.2021Veröffentlicht in Annual review of immunology (26.04.2021)“… The immune system of the central nervous system (CNS) consists primarily of innate immune cells. These are highly specialized macrophages found either in the …”
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Function and therapeutic value of astrocytes in neurological diseases
ISSN: 1474-1776, 1474-1784, 1474-1784Veröffentlicht: England Nature Publishing Group 01.05.2022Veröffentlicht in Nature reviews. Drug discovery (01.05.2022)“… Astrocytes are abundant glial cells in the central nervous system (CNS) that perform diverse functions in health and disease. Astrocyte dysfunction is found in …”
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The Gut–CNS Axis in Multiple Sclerosis
ISSN: 0166-2236, 1878-108X, 1878-108XVeröffentlicht: Elsevier Ltd 01.08.2020Veröffentlicht in Trends in neurosciences (Regular ed.) (01.08.2020)“… Multiple sclerosis (MS) is an autoimmune inflammatory disease of the CNS driven by the inflammatory activity of peripheral immune cells recruited to the CNS …”
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Repositioning TH cell polarization from single cytokines to complex help
ISSN: 1529-2908, 1529-2916, 1529-2916Veröffentlicht: New York Nature Publishing Group US 01.10.2021Veröffentlicht in Nature immunology (01.10.2021)“… When helper T (T H ) cell polarization was initially described three decades ago, the T H cell universe grew dramatically. New subsets were described based on …”
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Multiple sclerosis: Neuroimmune crosstalk and therapeutic targeting
ISSN: 1097-4172, 1097-4172Veröffentlicht: United States 30.03.2023Veröffentlicht in Cell (30.03.2023)“… Multiple sclerosis (MS) is a chronic inflammatory and degenerative disease of the central nervous system afflicting nearly three million individuals worldwide …”
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Digestion of Chromatin in Apoptotic Cell Microparticles Prevents Autoimmunity
ISSN: 1097-4172, 1097-4172Veröffentlicht: United States 30.06.2016Veröffentlicht in Cell (30.06.2016)“… Antibodies to DNA and chromatin drive autoimmunity in systemic lupus erythematosus (SLE). Null mutations and hypomorphic variants of the secreted …”
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Treg cells expressing the coinhibitory molecule TIGIT selectively inhibit proinflammatory Th1 and Th17 cell responses
ISSN: 1097-4180, 1097-4180Veröffentlicht: United States 17.04.2014Veröffentlicht in Immunity (Cambridge, Mass.) (17.04.2014)“… Foxp3(+) T regulatory (Treg) cells regulate immune responses and maintain self-tolerance. Recent work shows that Treg cells are comprised of many …”
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Astrocytes to the rescue! Glia limitans astrocytic endfeet control CNS inflammation
ISSN: 0021-9738, 1558-8238, 1558-8238Veröffentlicht: United States American Society for Clinical Investigation 01.08.2017Veröffentlicht in The Journal of clinical investigation (01.08.2017)“… The blood-brain barrier (BBB) and the glia limitans serve to prevent the migration of cells and other large molecules from the blood into the CNS …”
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Therapeutic induction of antigen-specific immune tolerance
ISSN: 1474-1733, 1474-1741, 1474-1741Veröffentlicht: England Nature Publishing Group 01.05.2024Veröffentlicht in Nature reviews. Immunology (01.05.2024)“… The development of therapeutic approaches for the induction of robust, long-lasting and antigen-specific immune tolerance remains an important unmet clinical …”
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Small Powers, International Organizations and the Role of Law: Jorge Castañeda’s Views from Mexico
ISSN: 0938-5428, 1464-3596Veröffentlicht: UK Oxford University Press 06.07.2023Veröffentlicht in European journal of international law (06.07.2023)“… Abstract This article examines the work of Mexican diplomat and jurist Jorge Castañeda as an insight into the trajectory of international legal thought in the …”
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The Immune Response in Multiple Sclerosis
ISSN: 1553-4014, 1553-4014Veröffentlicht: United States 24.01.2022Veröffentlicht in Annual review of pathology (24.01.2022)“… Multiple sclerosis (MS) is a chronic autoimmune, inflammatory, and neurodegenerative disease that affects the central nervous system (CNS). MS is characterized …”
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Neuroinflammation: An astrocyte perspective
ISSN: 1946-6242, 1946-6242Veröffentlicht: United States 08.11.2023Veröffentlicht in Science translational medicine (08.11.2023)“… Astrocytes are abundant glial cells in the central nervous system (CNS) that play active roles in health and disease. Recent technologies have uncovered the …”
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Regulation of the T Cell Response by CD39
ISSN: 1471-4906, 1471-4981, 1471-4981Veröffentlicht: England Elsevier Ltd 01.07.2016Veröffentlicht in Trends in immunology (01.07.2016)“… The ectonucleoside triphosphate diphosphohydrolase 1 (ENTPD1, or CD39) catalyzes the phosphohydrolysis of extracellular ATP (eATP) and ADP (eADP) released …”
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Functional immune cell-astrocyte interactions
ISSN: 1540-9538, 1540-9538Veröffentlicht: United States 06.09.2021Veröffentlicht in The Journal of experimental medicine (06.09.2021)“… Astrocytes are abundant glial cells in the central nervous system (CNS) that control multiple aspects of health and disease. Through their interactions with …”
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Aryl hydrocarbon receptor control of adaptive immunity
ISSN: 1521-0081, 1521-0081Veröffentlicht: United States 01.10.2013Veröffentlicht in Pharmacological reviews (01.10.2013)“… The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that belongs to the family of basic helix-loop-helix transcription factors …”
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Dollar dominance, de-dollarization, and international law
ISSN: 1369-3034, 1464-3758Veröffentlicht: Oxford University PressVeröffentlicht in Journal of international economic law“… Abstract Recent proposals to seize Russian Central Bank assets expose how little international lawyers have engaged with the intensifying competition over …”
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