Search Results - "Proteins"

Regulation of sarcomagenesis by the empty spiracles homeobox genes EMX1 and EMX2 by Amancio Carnero, Manuel P. Jiménez-García, Daniel Otero-Albiol, Antonio Lucena-Cacace

“…The EMX (Empty Spiracles Homeobox) genes EMX1 and EMX2 are two homeodomain gene members of the EMX family of transcription factors involved in the regulation…”
Get full text

Endurance exercise training up-regulates lipolytic proteins and reduces triglyceride content in skeletal muscle of obese subjects by Louche, Katie, Badin, Pierre-Marie, Montastier, Emilie, Laurens, Claire, Bourlier, Virginie, de Glisezinski, Isabelle, Thalamas, Claire, Viguerie, Nathalie, Langin, Dominique, Moro, Cedric

“… The aim of the present study was to investigate the impact of 8 weeks of endurance exercise training on IMTG content and lipolytic proteins in obese male subjects…”
Get more information

Structural analysis of the GPI glycan by Nakano, Miyako, Sabido-Bozo, Susana, Okazaki, Kouta, Aguilera-Romero, Auxiliadora, Rodriguez-Gallardo, Sofia, Cortes-Gomez, Alejandro, Lopez, Sergio, Ikeda, Atsuko, Funato, Kouichi, Muñiz, Manuel

“…Glycosylphosphatidylinositol (GPI) anchoring of proteins is an essential post-translational modification in all eukaryotes that occurs at the endoplasmic reticulum (ER…”
Get full text

TDP-43 extracted from frontotemporal lobar degeneration subject brains displays distinct aggregate assemblies and neurotoxic effects reflecting disease progression rates by Laferrière, Florent, Maniecka, Zuzanna, Pérez-Berlanga, Manuela, Hruska-Plochan, Marian, Gilhespy, Larissa, Hock, Eva-Maria, Wagner, Ulrich, Afroz, Tariq, Boersema, Paul J, Barmettler, Gery, Foti, Sandrine C, Asi, Yasmine T, Isaacs, Adrian M, Al-Amoudi, Ashraf, Lewis, Amanda, Stahlberg, Henning, Ravits, John, De Giorgi, Francesca, Ichas, François, Bezard, Erwan, Picotti, Paola, Lashley, Tammaryn, Polymenidou, Magdalini

“… By combining SarkoSpin with mass spectrometry, we revealed proteins beyond TDP-43 that become abnormally insoluble in a disease subtype-specific manner…”
Get full text

Similar dietary regulation of IGF-1- and IGF-binding proteins by animal and plant protein in subjects with type 2 diabetes by Schüler, Rita, Markova, Mariya, Osterhoff, Martin A., Arafat, Ayman, Pivovarova, Olga, Machann, Jürgen, Hierholzer, Johannes, Hornemann, Silke, Rohn, Sascha, Pfeiffer, Andreas F. H.

“…Increased animal but not plant protein intake has been associated with increased mortality in epidemiological studies in humans and with reduced lifespan in animal species…”
Get full text

Interleukin-6 (IL-6) induces insulin resistance in 3T3-L1 adipocytes and is, like IL-8 and tumor necrosis factor-alpha, overexpressed in human fat cells from insulin-resistant subjects by Rotter, Victoria, Nagaev, Ivan, Smith, Ulf

“… This effect of IL-6 was accompanied by a marked reduction in IRS-1, but not IRS-2, protein expression, and insulin-stimulated tyrosine phosphorylation, whereas no inhibitory effect was seen…”
Get more information

Increased Toll-Like Receptor (TLR) Activation and TLR Ligands in Recently Diagnosed Type 2 Diabetic Subjects by Dasu, Mohan R, Devaraj, Sridevi, Park, Samuel, Jialal, Ishwarlal

“… RESEARCH DESIGN AND METHODS: TLR mRNA, protein expression, TLR ligands, and TLR signaling were measured in freshly isolated monocytes from healthy human control subjects (n = 23…”
Get full text

TOMM40 and APOE Gene Expression and Cognitive Decline in Japanese Alzheimer's Disease Subjects by Mise, Ayano, Yoshino, Yuta, Yamazaki, Kiyohiro, Ozaki, Yuki, Sao, Tomoko, Yoshida, Taku, Mori, Takaaki, Mori, Yoko, Ochi, Shinichiro, Iga, Jun-Ichi, Ueno, Shu-Ichi

“…), Parkin RBR E3 ubiquitin protein ligase (PARK2), and APOE mRNA expression in relation to the methylation rates of CpG sites in the upstream region of TOMM40exon 1 in peripheral leukocytes and TOMM40523 polyT genotypes in 60 AD and age- and sex…”
Get more information

Bioluminescence resonance energy transfer (BRET) imaging of protein-protein interactions within deep tissues of living subjects by Dragulescu-Andrasi, Anca, Chan, Carmel T, De, Abhijit, Massoud, Tarik F, Gambhir, Sanjiv S

“…Identifying protein-protein interactions (PPIs) is essential for understanding various disease mechanisms and developing new therapeutic approaches…”
Get more information

Low‐calorie, high‐protein diets, regardless of protein source, improve glucose metabolism and cardiometabolic profiles in subjects with prediabetes or type 2 diabetes and overweight or obesity by Rodrigo‐Carbó, Carmen, Madinaveitia‐Nisarre, Loreto, Pérez‐Calahorra, Sofía, Gracia‐Rubio, Irene, Cebollada, Alberto, Galindo‐Lalana, Carlos, Mateo‐Gallego, Rocío, Lamiquiz‐Moneo, Itziar

“…Aim The aim was to study the effect of two low‐calorie, high‐protein (HP) diets, with most of the protein coming from animal or plant sources, on glycaemic…”
Get full text

Protein supplementation improves muscle mass and physical performance in undernourished prefrail and frail elderly subjects: a randomized, double-blind, placebo-controlled trial by Park, Yongsoon, Choi, Jeong-Eun, Hwang, Hwan-Sik

“…Age-related loss of muscle mass and function is a major component of frailty. Nutrition supplementation with exercise is an effective strategy to decrease frailty by preventing sarcopenia, but the effect of protein alone is controversial…”
Get more information

Altered expression of synapse and glutamate related genes in post-mortem hippocampus of depressed subjects by Duric, Vanja, Banasr, Mounira, Stockmeier, Craig A., Simen, Arthur A., Newton, Samuel S., Overholser, James C., Jurjus, George J., Dieter, Lesa, Duman, Ronald S.

“… In this study, we examined the genetic profile of micro-dissected subfields of post-mortem hippocampus from subjects diagnosed with MDD and comparison subjects matched for sex, race and age…”
Get full text

Analyses of asthma severity phenotypes and inflammatory proteins in subjects stratified by sputum granulocytes by Hastie, Annette T., Moore, Wendy C., Meyers, Deborah A., Vestal, Penny L., Li, Huashi, Peters, Stephen P., Bleecker, Eugene R.

“… We hypothesized that inflammatory granulocytes in sputum may identify specific asthma severity phenotypes and are associated with different patterns of inflammatory proteins in sputum supernatants…”
Get full text

Effects of Animal and Vegetable Proteins on Gut Microbiota in Subjects with Overweight or Obesity by Di Rosa, Claudia, Di Francesco, Ludovica, Spiezia, Chiara, Khazrai, Yeganeh Manon

“… in subjects with overweight and obesity. Several studies have shown that a higher intake of animal protein, as well as the Western…”
Get full text

Proteomic and histopathological characterisation of sicca subjects and primary Sjögren’s syndrome patients reveals promising tear, saliva and extracellular vesicle disease biomarkers by Aqrawi, Lara A., Galtung, Hilde Kanli, Guerreiro, Eduarda M., Øvstebø, Reidun, Thiede, Bernd, Utheim, Tor Paaske, Chen, Xiangjun, Utheim, Øygunn Aass, Palm, Øyvind, Skarstein, Kathrine, Jensen, Janicke Liaaen

“…). Non-SS sicca subjects, an underexplored group in relation to pSS, display similar sicca symptoms, with possible mild signs of inflammation in their salivary glands, yet with no serological detection…”
Get full text

European Biological Variation Study (EuBIVAS): Within- and Between-Subject Biological Variation Data for 15 Frequently Measured Proteins by Carobene, Anna, Aarsand, Aasne K, Guerra, Elena, Bartlett, William A, Coşkun, Abdurrahman, Díaz-Garzón, Jorge, Fernandez-Calle, Pilar, Jonker, Niels, Locatelli, Massimo, Sandberg, Sverre, Ceriotti, Ferruccio

“… -microglobulin, ceruloplasmin, complement component 3, complement component 4, C-reactive protein (CRP…”
Get full text

Assessing the whole-body protein synthetic response to feeding in vivo in human subjects by Trommelen, Jorn, van Loon, Luc J. C.

“… Due to the relative ease of sampling skeletal muscle tissue, basal muscle protein synthesis rates and the protein synthetic responses to various anabolic stimuli have been well defined in human subjects…”
Get full text

Interaction of amyloidogenic proteins in pancreatic β cells from subjects with synucleinopathies by Martinez-Valbuena, Ivan, Amat-Villegas, Irene, Valenti-Azcarate, Rafael, Carmona-Abellan, Maria del Mar, Marcilla, Irene, Tuñon, Maria-Teresa, Luquin, Maria-Rosario

“… Thus, we have investigated whether phosphorylated α-synuclein is deposited in pancreatic tissue of subjects with synucleinopathies…”
Get full text

Niacin Increases Atherogenic Proteins in High-Density Lipoprotein of Statin-Treated Subjects by Ronsein, Graziella E, Vaisar, Tomas, Davidson, W Sean, Bornfeldt, Karin E, Probstfield, Jeffrey L, O'Brien, Kevin D, Zhao, Xue-Qiao, Heinecke, Jay W

“…). APPROACH AND RESULTS: Using targeted proteomics, we quantified levels of 31 HDL proteins from 124 CPC subjects and 120 AIM-HIGH subjects…”
Get more information

Endosome and Golgi‐associated degradation (EGAD) of membrane proteins regulates sphingolipid metabolism by Schmidt, Oliver, Weyer, Yannick, Baumann, Verena, Widerin, Michael A, Eising, Sebastian, Angelova, Mihaela, Schleiffer, Alexander, Kremser, Leopold, Lindner, Herbert, Peter, Matthias, Fröhlich, Florian, Teis, David

“…Cellular homeostasis requires the ubiquitin‐dependent degradation of membrane proteins…”
Get full text